GB9213215D0 - Peptides - Google Patents
PeptidesInfo
- Publication number
- GB9213215D0 GB9213215D0 GB929213215A GB9213215A GB9213215D0 GB 9213215 D0 GB9213215 D0 GB 9213215D0 GB 929213215 A GB929213215 A GB 929213215A GB 9213215 A GB9213215 A GB 9213215A GB 9213215 D0 GB9213215 D0 GB 9213215D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- pct
- peptides
- sec
- date
- pub
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 101710151321 Melanostatin Proteins 0.000 abstract 1
- 102400000064 Neuropeptide Y Human genes 0.000 abstract 1
- 230000008485 antagonism Effects 0.000 abstract 1
- URPYMXQQVHTUDU-OFGSCBOVSA-N nucleopeptide y Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 URPYMXQQVHTUDU-OFGSCBOVSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57545—Neuropeptide Y
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929213215A GB9213215D0 (en) | 1992-06-20 | 1992-06-20 | Peptides |
| DE69326250T DE69326250D1 (de) | 1992-06-20 | 1993-06-18 | Neuropeptide y antagoniste |
| MX9303694A MX9303694A (es) | 1992-06-20 | 1993-06-18 | Peptidos. |
| US08/360,706 US5670482A (en) | 1992-06-20 | 1993-06-18 | Neuropeptide Y antagonists |
| IL10606093A IL106060A (en) | 1992-06-20 | 1993-06-18 | YPN neuropeptide Y antagonists and pharmaceutical preparations containing them |
| EP93913398A EP0672055B1 (en) | 1992-06-20 | 1993-06-18 | Neuropeptide y antagonists |
| PCT/GB1993/001297 WO1994000486A1 (en) | 1992-06-20 | 1993-06-18 | Neuropeptide y antagonists |
| JP6502136A JPH07508273A (ja) | 1992-06-20 | 1993-06-18 | 神経ペプチドｙ拮抗剤 |
| AT93913398T ATE184022T1 (de) | 1992-06-20 | 1993-06-18 | Neuropeptide y antagoniste |
| TW082104939A TW279166B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-06-20 | 1993-06-18 | |
| AU43488/93A AU4348893A (en) | 1992-06-20 | 1993-06-18 | Neuropeptide y antagonists |
| CA002138374A CA2138374A1 (en) | 1992-06-20 | 1993-06-18 | Neuropeptide y antagonists |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929213215A GB9213215D0 (en) | 1992-06-20 | 1992-06-20 | Peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9213215D0 true GB9213215D0 (en) | 1992-08-05 |
Family
ID=10717514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB929213215A Pending GB9213215D0 (en) | 1992-06-20 | 1992-06-20 | Peptides |
Country Status (12)
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5516653A (en) | 1993-12-28 | 1996-05-14 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof |
| US5545549A (en) | 1994-02-03 | 1996-08-13 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
| US5696093A (en) * | 1994-10-28 | 1997-12-09 | Crc For Biopharmaceutical Research Pty Limited | Method of treating nasal congestion using neuropeptide Y Y2 agonist peptides |
| US5989920A (en) | 1994-12-02 | 1999-11-23 | Synaptic Pharmaceutical Corporation | Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5 |
| US5602024A (en) | 1994-12-02 | 1997-02-11 | Synaptic Pharmaceutical Corporation | DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof |
| WO1997034873A1 (fr) * | 1996-03-21 | 1997-09-25 | Banyu Pharmaceutical Co., Ltd. | Derives d'aminopyridine |
| US6265215B1 (en) * | 1996-09-13 | 2001-07-24 | Ludwig Institute For Cancer Research | Isolated peptides which complex with HLA-Cw16 and uses thereof |
| FR2754709B1 (fr) | 1996-10-23 | 1999-03-05 | Sanofi Sa | Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition |
| WO1998040356A1 (fr) * | 1997-03-12 | 1998-09-17 | Banyu Pharmaceutical Co., Ltd. | Medicaments contenant des derives d'aminopyridine comme ingredient actif |
| US6713265B1 (en) | 1997-06-04 | 2004-03-30 | Synaptic Pharmaceutical Corporation | Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) |
| US6046167A (en) * | 1998-03-25 | 2000-04-04 | University Of Cincinnati | Peptide YY analogs |
| WO2000030674A1 (en) * | 1998-11-26 | 2000-06-02 | Ferring Bv | Neuropeptide y y4 agents in the treatment of reproductive disorders |
| WO2001053477A1 (en) * | 2000-01-20 | 2001-07-26 | Baylor College Of Medicine | Methods and compositions for control of bone formation via modulation of neuropeptide y activity |
| AU2002348131A1 (en) | 2001-12-05 | 2003-06-23 | Baylor College Of Medicine | Methods and compositions for control of bone formation via modulation of sympathetic tone |
| GB0130219D0 (en) * | 2001-12-18 | 2002-02-06 | Pfizer Ltd | Compounds for the treatment of sexual dysfunction |
| ATE462432T1 (de) | 2003-05-05 | 2010-04-15 | Probiodrug Ag | Glutaminylcyclase-hemmer |
| CA2544573A1 (en) | 2003-11-03 | 2005-06-02 | Probiodrug Ag | Combinations useful for the treatment of neuronal disorders |
| WO2005075436A2 (en) | 2004-02-05 | 2005-08-18 | Probiodrug Ag | Novel inhibitors of glutaminyl cyclase |
| US20090213731A1 (en) * | 2005-04-15 | 2009-08-27 | Regenertech Pty Limited | Use of neuropeptide y (npy) and agonists and antagonists thereof for tissue regeneration |
| WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
| DK2091948T3 (da) | 2006-11-30 | 2012-07-23 | Probiodrug Ag | Nye inhibitorer af glutaminylcyclase |
| KR20090115951A (ko) | 2007-03-01 | 2009-11-10 | 프로비오드룩 아게 | 글루타미닐 사이클라제 저해제의 신규 용도 |
| ES2533484T3 (es) | 2007-04-18 | 2015-04-10 | Probiodrug Ag | Derivados de tiourea como inhibidores de la glutaminil ciclasa |
| WO2009110510A1 (ja) | 2008-03-06 | 2009-09-11 | 萬有製薬株式会社 | アルキルアミノピリジン誘導体 |
| KR101755737B1 (ko) | 2009-09-11 | 2017-07-07 | 프로비오드룩 아게 | 글루타미닐 사이클라제의 억제제로서 헤테로사이클릭 유도체 |
| CA2789879A1 (en) * | 2009-10-28 | 2011-05-19 | Joyant Pharmaceuticals, Inc. | Dimeric smac mimetics |
| US9181233B2 (en) | 2010-03-03 | 2015-11-10 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| CA2789440C (en) | 2010-03-10 | 2020-03-24 | Probiodrug Ag | Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5) |
| JP5945532B2 (ja) | 2010-04-21 | 2016-07-05 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤としてのベンゾイミダゾール誘導体 |
| ES2570167T3 (es) | 2011-03-16 | 2016-05-17 | Probiodrug Ag | Derivados de benzimidazol como inhibidores de glutaminil ciclasa |
| EP3461819B1 (en) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4602019A (en) * | 1983-04-22 | 1986-07-22 | Warner-Lambert Company | Indeno[1,2-c]pyridazin-3-one derivatives useful as cardiotonic and antihypertensive agents |
| US5128332A (en) * | 1984-10-23 | 1992-07-07 | Perstorp Ab | Method of treating cardiovascular diseases using inositoltrisphosphate |
| US5330979A (en) * | 1984-10-23 | 1994-07-19 | Perstorp Ab | Method of treating renal disorders with inositoltriphosphate |
| US4891357A (en) * | 1985-02-11 | 1990-01-02 | University Of Florida | Methods and compositions for stimulation of appetite |
| US4897445A (en) * | 1986-06-27 | 1990-01-30 | The Administrators Of The Tulane Educational Fund | Method for synthesizing a peptide containing a non-peptide bond |
| JPS646294A (en) * | 1987-02-09 | 1989-01-10 | Ajinomoto Kk | Novel peptide derivative |
| US4839343A (en) * | 1987-03-13 | 1989-06-13 | Debiopharm, S.A. | Preparation containing hexatriacontapeptides and methods of use |
| US6255067B1 (en) * | 1987-09-15 | 2001-07-03 | The Johns Hopkins University | cDNA encoding peptidyl-glycine alpha-amidating monooxygenase (PAM) |
| DE3811193A1 (de) * | 1988-04-01 | 1989-10-19 | Boehringer Ingelheim Kg | Neue peptide, verfahren zu ihrer herstellung und diese peptide enthaltende pharmazeutische zusammensetzungen |
| DE3813592A1 (de) * | 1988-04-22 | 1989-11-02 | Hoechst Ag | Monoklonale antikoerper gegen das neuropeptid y, verfahren zu ihrer herstellung sowie ihre verwendung |
| US5328899A (en) * | 1988-07-15 | 1994-07-12 | The Salk Institute For Biological Studies | NPY peptide analogs |
| ZA896374B (en) * | 1988-08-26 | 1990-05-30 | Merrell Dow Pharma | Neuropeptide y antagonists |
| ZA896376B (en) * | 1988-08-26 | 1990-05-30 | Merrell Dow Pharma | Neuropeptide y agonists |
| SE9002278L (sv) * | 1990-06-28 | 1991-12-29 | Perstorp Ab | Anvaendning av inositoltrisfosfat foer framstaellning av ett laekemedel |
-
1992
- 1992-06-20 GB GB929213215A patent/GB9213215D0/en active Pending
-
1993
- 1993-06-18 TW TW082104939A patent/TW279166B/zh active
- 1993-06-18 AT AT93913398T patent/ATE184022T1/de not_active IP Right Cessation
- 1993-06-18 WO PCT/GB1993/001297 patent/WO1994000486A1/en active IP Right Grant
- 1993-06-18 AU AU43488/93A patent/AU4348893A/en not_active Abandoned
- 1993-06-18 JP JP6502136A patent/JPH07508273A/ja active Pending
- 1993-06-18 US US08/360,706 patent/US5670482A/en not_active Expired - Fee Related
- 1993-06-18 DE DE69326250T patent/DE69326250D1/de not_active Expired - Lifetime
- 1993-06-18 IL IL10606093A patent/IL106060A/en not_active IP Right Cessation
- 1993-06-18 EP EP93913398A patent/EP0672055B1/en not_active Expired - Lifetime
- 1993-06-18 CA CA002138374A patent/CA2138374A1/en not_active Abandoned
- 1993-06-18 MX MX9303694A patent/MX9303694A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9303694A (es) | 1994-05-31 |
| US5670482A (en) | 1997-09-23 |
| IL106060A (en) | 1998-10-30 |
| TW279166B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-06-21 |
| WO1994000486A1 (en) | 1994-01-06 |
| AU4348893A (en) | 1994-01-24 |
| EP0672055B1 (en) | 1999-09-01 |
| JPH07508273A (ja) | 1995-09-14 |
| DE69326250D1 (de) | 1999-10-07 |
| EP0672055A1 (en) | 1995-09-20 |
| IL106060A0 (en) | 1993-10-20 |
| CA2138374A1 (en) | 1994-01-06 |
| ATE184022T1 (de) | 1999-09-15 |
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