GB9013345D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
GB9013345D0
GB9013345D0 GB909013345A GB9013345A GB9013345D0 GB 9013345 D0 GB9013345 D0 GB 9013345D0 GB 909013345 A GB909013345 A GB 909013345A GB 9013345 A GB9013345 A GB 9013345A GB 9013345 D0 GB9013345 D0 GB 9013345D0
Authority
GB
United Kingdom
Prior art keywords
novel compounds
novel
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB909013345A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB909013345A priority Critical patent/GB9013345D0/en
Publication of GB9013345D0 publication Critical patent/GB9013345D0/en
Priority to NZ238506A priority patent/NZ238506A/xx
Priority to PCT/GB1991/000945 priority patent/WO1991019793A2/en
Priority to EP91910869A priority patent/EP0535037A1/en
Priority to CA002085224A priority patent/CA2085224A1/en
Priority to KR1019920703217A priority patent/KR930701607A/ko
Priority to IE199991A priority patent/IE911999A1/en
Priority to AU80681/91A priority patent/AU648567B2/en
Priority to ZA914520A priority patent/ZA914520B/xx
Priority to JP91510746A priority patent/JPH05506363A/ja
Priority to IL98478A priority patent/IL98478A0/xx
Priority to PT97983A priority patent/PT97983A/pt
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fixing For Electrophotography (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB909013345A 1990-06-14 1990-06-14 Novel compounds Pending GB9013345D0 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
GB909013345A GB9013345D0 (en) 1990-06-14 1990-06-14 Novel compounds
JP91510746A JPH05506363A (ja) 1990-06-14 1991-06-12 新規化合物
CA002085224A CA2085224A1 (en) 1990-06-14 1991-06-12 Hybrid plasminogen activators
PCT/GB1991/000945 WO1991019793A2 (en) 1990-06-14 1991-06-12 Hybrid plasminogen activators
EP91910869A EP0535037A1 (en) 1990-06-14 1991-06-12 Hybrid plasminogen activators
NZ238506A NZ238506A (en) 1990-06-14 1991-06-12 4-methoxybenzoyl plasminogen 1-541/t-pa 262-527, variants, its production and use
KR1019920703217A KR930701607A (ko) 1990-06-14 1991-06-12 하이브리드 플라스미노겐 활성제
IE199991A IE911999A1 (en) 1990-06-14 1991-06-12 Novel compounds
AU80681/91A AU648567B2 (en) 1990-06-14 1991-06-12 Hybrid plasminogen activators
ZA914520A ZA914520B (en) 1990-06-14 1991-06-12 Hybrid plasminogen activators
IL98478A IL98478A0 (en) 1990-06-14 1991-06-13 Hybrid fibrinolytic enzyme,its preparation and pharmaceutical compositions containing it
PT97983A PT97983A (pt) 1990-06-14 1991-06-14 Processo para a preparacao de um enzima fibrinolitico hibrido, nomeadamente um derivado de plaminogenio

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909013345A GB9013345D0 (en) 1990-06-14 1990-06-14 Novel compounds

Publications (1)

Publication Number Publication Date
GB9013345D0 true GB9013345D0 (en) 1990-08-08

Family

ID=10677652

Family Applications (1)

Application Number Title Priority Date Filing Date
GB909013345A Pending GB9013345D0 (en) 1990-06-14 1990-06-14 Novel compounds

Country Status (12)

Country Link
EP (1) EP0535037A1 (xx)
JP (1) JPH05506363A (xx)
KR (1) KR930701607A (xx)
AU (1) AU648567B2 (xx)
CA (1) CA2085224A1 (xx)
GB (1) GB9013345D0 (xx)
IE (1) IE911999A1 (xx)
IL (1) IL98478A0 (xx)
NZ (1) NZ238506A (xx)
PT (1) PT97983A (xx)
WO (1) WO1991019793A2 (xx)
ZA (1) ZA914520B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1135475A1 (en) * 1998-12-02 2001-09-26 Oklahoma Medical Research Foundation Human plasminogen activator

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions
GB8334498D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Compounds
EP0297882B1 (en) * 1987-07-01 1993-08-25 Beecham Group Plc Hybrid plasminogen activators
GB9019120D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
IE911999A1 (en) 1991-12-18
AU8068191A (en) 1992-01-07
IL98478A0 (en) 1992-07-15
AU648567B2 (en) 1994-04-28
KR930701607A (ko) 1993-06-12
ZA914520B (en) 1992-12-30
CA2085224A1 (en) 1991-12-15
PT97983A (pt) 1992-04-30
EP0535037A1 (en) 1993-04-07
NZ238506A (en) 1993-07-27
WO1991019793A3 (en) 1992-01-23
JPH05506363A (ja) 1993-09-22
WO1991019793A2 (en) 1991-12-26

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