GB900572A - Funtumia alkaloids - Google Patents
Funtumia alkaloidsInfo
- Publication number
- GB900572A GB900572A GB30862/58A GB3086258A GB900572A GB 900572 A GB900572 A GB 900572A GB 30862/58 A GB30862/58 A GB 30862/58A GB 3086258 A GB3086258 A GB 3086258A GB 900572 A GB900572 A GB 900572A
- Authority
- GB
- United Kingdom
- Prior art keywords
- funtumine
- funtumidine
- acid
- amino
- plants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000983373 Funtumia Species 0.000 title abstract 3
- 229930013930 alkaloid Natural products 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 12
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 8
- POWBIOMTXFDIOP-UHFFFAOYSA-N Funtumin Natural products C1CC2CC(N)CCC2(C)C2C1C1CCC(C(=O)C)C1(C)CC2 POWBIOMTXFDIOP-UHFFFAOYSA-N 0.000 abstract 8
- POWBIOMTXFDIOP-SYBPFIFISA-N Funtumine Chemical compound C([C@@H]1CC2)[C@H](N)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)C)[C@@]2(C)CC1 POWBIOMTXFDIOP-SYBPFIFISA-N 0.000 abstract 8
- POWBIOMTXFDIOP-LHYDXMHHSA-N Funtumine Natural products O=C(C)[C@@H]1[C@]2(C)[C@H]([C@@H]3[C@@H]([C@]4(C)[C@H](C[C@H](N)CC4)CC3)CC2)CC1 POWBIOMTXFDIOP-LHYDXMHHSA-N 0.000 abstract 8
- VIQFMADXQMGZER-CGVINKDUSA-N (1s)-1-[(3r,5s,8r,9s,10s,13s,14s,17s)-3-amino-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]ethanol Chemical compound C([C@@H]1CC2)[C@H](N)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](O)C)[C@@]2(C)CC1 VIQFMADXQMGZER-CGVINKDUSA-N 0.000 abstract 7
- VIQFMADXQMGZER-UHFFFAOYSA-N (20S) 3alpha-amino-5alpha-pregnane-20-ol Natural products C1CC2CC(N)CCC2(C)C2C1C1CCC(C(O)C)C1(C)CC2 VIQFMADXQMGZER-UHFFFAOYSA-N 0.000 abstract 6
- WNTILTUNFXLYHC-UHFFFAOYSA-N (3alpha,5alpha,20R)-3-Aminopregnan-20-ol Natural products C1CC2C(O)C(O)CCC2(C)C2C1C1CCC(C(N)C)C1(C)CC2 WNTILTUNFXLYHC-UHFFFAOYSA-N 0.000 abstract 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 4
- 241000196324 Embryophyta Species 0.000 abstract 4
- 239000000243 solution Substances 0.000 abstract 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 230000001590 oxidative effect Effects 0.000 abstract 3
- 239000002904 solvent Substances 0.000 abstract 3
- 238000005406 washing Methods 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 241001411211 Funtumia africana Species 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000003513 alkali Substances 0.000 abstract 2
- KRVSOGSZCMJSLX-UHFFFAOYSA-L chromic acid Substances O[Cr](O)(=O)=O KRVSOGSZCMJSLX-UHFFFAOYSA-L 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- 238000001704 evaporation Methods 0.000 abstract 2
- AWJWCTOOIBYHON-UHFFFAOYSA-N furo[3,4-b]pyrazine-5,7-dione Chemical compound C1=CN=C2C(=O)OC(=O)C2=N1 AWJWCTOOIBYHON-UHFFFAOYSA-N 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- XMRPGKVKISIQBV-BJMCWZGWSA-N 5alpha-pregnane-3,20-dione Chemical compound C([C@@H]1CC2)C(=O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)C)[C@@]2(C)CC1 XMRPGKVKISIQBV-BJMCWZGWSA-N 0.000 abstract 1
- QDHHCQZDFGDHMP-UHFFFAOYSA-N Chloramine Chemical compound ClN QDHHCQZDFGDHMP-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 244000048879 Funtumia elastica Species 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- OHLUUHNLEMFGTQ-UHFFFAOYSA-N N-methylacetamide Chemical compound CNC(C)=O OHLUUHNLEMFGTQ-UHFFFAOYSA-N 0.000 abstract 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric Acid Chemical compound [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 230000000382 dechlorinating effect Effects 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- WQLVFSAGQJTQCK-UHFFFAOYSA-N diosgenin Natural products CC1C(C2(CCC3C4(C)CCC(O)CC4=CCC3C2C2)C)C2OC11CCC(C)CO1 WQLVFSAGQJTQCK-UHFFFAOYSA-N 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 150000004658 ketimines Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000004965 peroxy acids Chemical class 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910000105 potassium hydride Inorganic materials 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000009877 rendering Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- NWMIYTWHUDFRPL-UHFFFAOYSA-N sapogenin Natural products COC(=O)C1(CO)C(O)CCC2(C)C1CCC3(C)C2CC=C4C5C(C)(O)C(C)CCC5(CCC34C)C(=O)O NWMIYTWHUDFRPL-UHFFFAOYSA-N 0.000 abstract 1
- 150000003333 secondary alcohols Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000011975 tartaric acid Substances 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G5/00—Alkaloids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE443246 | 1957-09-27 | ||
| BE561173T | 1957-09-27 | ||
| LU35817 | 1958-02-22 | ||
| LU36147 | 1958-06-04 | ||
| DES60064A DE1185183B (de) | 1957-09-27 | 1958-09-27 | Verfahren zur Gewinnung und Herstellung von herzaktiven bzw. hormonal wirksamen Verbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB900572A true GB900572A (en) | 1962-07-11 |
Family
ID=27507596
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB30862/58A Expired GB900572A (en) | 1957-09-27 | 1958-09-26 | Funtumia alkaloids |
| GB5360/60A Expired GB948769A (en) | 1957-09-27 | 1960-02-15 | New alkaloids of the funtumia species and processes for obtaining same |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5360/60A Expired GB948769A (en) | 1957-09-27 | 1960-02-15 | New alkaloids of the funtumia species and processes for obtaining same |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE561173A (enrdf_load_stackoverflow) |
| CH (3) | CH405305A (enrdf_load_stackoverflow) |
| GB (2) | GB900572A (enrdf_load_stackoverflow) |
| LU (2) | LU36147A1 (enrdf_load_stackoverflow) |
| NL (1) | NL231702A (enrdf_load_stackoverflow) |
| OA (1) | OA01015A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011127465A3 (en) * | 2010-04-09 | 2012-03-15 | The Research Foundation Of The State University Of New York | Ship inhibitors and uses thereof |
| US10702538B2 (en) | 2014-06-17 | 2020-07-07 | The Research Foundation For The State University Of New York | Ship inhibition to induce activation of natural killer cells |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2494697A1 (fr) * | 1980-11-21 | 1982-05-28 | Roussel Uclaf | Nouveaux derives steroides 3-amines, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
| FR2494696A1 (fr) * | 1980-11-21 | 1982-05-28 | Roussel Uclaf | Nouveau procede de preparation de steroides 3-amines et leurs sels |
-
0
- NL NL231702D patent/NL231702A/xx unknown
- LU LU35817D patent/LU35817A1/xx unknown
- LU LU36147D patent/LU36147A1/xx unknown
-
1957
- 1957-09-27 BE BE561173D patent/BE561173A/xx unknown
-
1958
- 1958-09-25 CH CH1173361A patent/CH405305A/fr unknown
- 1958-09-25 CH CH6436458A patent/CH370773A/fr unknown
- 1958-09-25 CH CH1173261A patent/CH369756A/fr unknown
- 1958-09-26 GB GB30862/58A patent/GB900572A/en not_active Expired
-
1960
- 1960-02-15 GB GB5360/60A patent/GB948769A/en not_active Expired
-
1964
- 1964-12-29 OA OA51120A patent/OA01015A/xx unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011127465A3 (en) * | 2010-04-09 | 2012-03-15 | The Research Foundation Of The State University Of New York | Ship inhibitors and uses thereof |
| US9447139B2 (en) | 2010-04-09 | 2016-09-20 | The Research Foundation Of State University Of New York | Ship inhibitors and uses thereof |
| US11319336B2 (en) | 2010-04-09 | 2022-05-03 | The Research Foundation For The State University Of New York | Ship inhibitors and uses thereof |
| US10702538B2 (en) | 2014-06-17 | 2020-07-07 | The Research Foundation For The State University Of New York | Ship inhibition to induce activation of natural killer cells |
Also Published As
| Publication number | Publication date |
|---|---|
| BE561173A (enrdf_load_stackoverflow) | 1960-05-20 |
| CH370773A (fr) | 1963-07-31 |
| CH369756A (fr) | 1963-06-15 |
| LU36147A1 (enrdf_load_stackoverflow) | |
| GB948769A (en) | 1964-02-05 |
| NL231702A (enrdf_load_stackoverflow) | |
| OA01015A (fr) | 1968-08-07 |
| CH405305A (fr) | 1966-01-15 |
| LU35817A1 (enrdf_load_stackoverflow) |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Galbraith et al. | Moretenol and other triterpenes from Ficus macrophylla Desf | |
| GB900572A (en) | Funtumia alkaloids | |
| Guise et al. | Further constituents of Alphitonia species | |
| Doy et al. | Alkaloids of Ochrosia poweri Bailey. I. The Leaf-bases | |
| US2790793A (en) | Process for obtaining pur chestnutsaponin | |
| US2248241A (en) | Method of preparing alkaloids from koto-tsuzurafuji | |
| US2099550A (en) | Antirachitic vitamin | |
| Badger et al. | 85. The alkaloids of Kreysigia multiflora Reichb. Part I. Isolation | |
| US3244696A (en) | Extraction of alkaloids from plants of genus holarrhena | |
| FUKAMACHI et al. | On the photolytic formation of 6, 7-dimethylflavin-9-acetic acid from riboflavin | |
| US2062904A (en) | Process for purifying hormones | |
| US2866784A (en) | Process for obtaining voacanga alkaloids | |
| US3682883A (en) | Process for extraction of solanum alkaloids | |
| Dukes et al. | Taxine. Part V. The structure of taxicin-II | |
| GB948485A (en) | New alkaloids and other new compounds from holarrhena species and processes for obtaining the same | |
| GB1012318A (en) | Processes for obtaining alkaloids of the funtumia species | |
| GB702072A (en) | Improvements in or relating to the production of hecogenin from plant material | |
| US2974144A (en) | Alkaloid and process for its production | |
| US3846434A (en) | Process for obtaining a germine adduct from germine values | |
| Laville et al. | The homolytic nitration of quinoline with pernitrous acid | |
| GB785987A (en) | Improvements in or relating to oestrogenic substances | |
| GB649286A (en) | Manufacture of phenol | |
| GB967080A (en) | Novel steroid compounds and process for the preparation thereof | |
| US2887489A (en) | Process and intermediate for | |
| DE1134386B (de) | Verfahren zur Gewinnung der Rauwolfia-Gesamtalkaloide |