GB899992A - Anti-protozoal compositions comprising hydroxyquinoline and nitrothiazole derivatives - Google Patents
Anti-protozoal compositions comprising hydroxyquinoline and nitrothiazole derivativesInfo
- Publication number
- GB899992A GB899992A GB44471/60A GB4447160A GB899992A GB 899992 A GB899992 A GB 899992A GB 44471/60 A GB44471/60 A GB 44471/60A GB 4447160 A GB4447160 A GB 4447160A GB 899992 A GB899992 A GB 899992A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxyquinoline
- radical
- compositions
- protozoal
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 title abstract 2
- ALNUOSXDMYFQNQ-UHFFFAOYSA-N 2-nitro-1,3-thiazole Chemical class [O-][N+](=O)C1=NC=CS1 ALNUOSXDMYFQNQ-UHFFFAOYSA-N 0.000 title 1
- 230000000842 anti-protozoal effect Effects 0.000 title 1
- 239000003904 antiprotozoal agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000005725 8-Hydroxyquinoline Substances 0.000 abstract 1
- QCDFBFJGMNKBDO-UHFFFAOYSA-N Clioquinol Chemical compound C1=CN=C2C(O)=C(I)C=C(Cl)C2=C1 QCDFBFJGMNKBDO-UHFFFAOYSA-N 0.000 abstract 1
- RDXLYGJSWZYTFJ-UHFFFAOYSA-N Niridazole Chemical compound S1C([N+](=O)[O-])=CN=C1N1C(=O)NCC1 RDXLYGJSWZYTFJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000224527 Trichomonas vaginalis Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 235000015110 jellies Nutrition 0.000 abstract 1
- 229960005130 niridazole Drugs 0.000 abstract 1
- 229960003540 oxyquinoline Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229940044959 vaginal cream Drugs 0.000 abstract 1
- 239000000522 vaginal cream Substances 0.000 abstract 1
- 229940044950 vaginal gel Drugs 0.000 abstract 1
- 239000000286 vaginal jelly Substances 0.000 abstract 1
- 229940044977 vaginal tablet Drugs 0.000 abstract 1
- 239000000003 vaginal tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55149A US3070498A (en) | 1960-09-12 | 1960-09-12 | Nitrothiazole-hydroxyquinoline compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB899992A true GB899992A (en) | 1962-06-27 |
Family
ID=21995944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB44471/60A Expired GB899992A (en) | 1960-09-12 | 1960-12-28 | Anti-protozoal compositions comprising hydroxyquinoline and nitrothiazole derivatives |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US3070498A (enrdf_load_stackoverflow) |
| FR (1) | FR817M (enrdf_load_stackoverflow) |
| GB (1) | GB899992A (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1635847B1 (en) * | 2003-06-13 | 2019-07-31 | IDH Holding ApS | Treatment of symptoms associated with bacterial vaginosis |
| GB0507490D0 (en) * | 2005-04-14 | 2005-05-18 | Aq & Plc | Treatment of animal parasites |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA558019A (en) * | 1958-05-27 | Merck And Co. Inc. | Therapeutic composition containing 2-amino-5-nitrothiazole | |
| CA524353A (en) * | 1956-04-24 | The Wellcome Foundation Limited | Antitrichomonal pessary | |
| US2675389A (en) * | 1952-01-09 | 1954-04-13 | Geza S Delmar | Arsanilate salts of hydroxyquinolines |
-
1960
- 1960-09-12 US US55149A patent/US3070498A/en not_active Expired - Lifetime
- 1960-12-23 FR FR847895A patent/FR817M/fr active Active
- 1960-12-28 GB GB44471/60A patent/GB899992A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3070498A (en) | 1962-12-25 |
| FR817M (enrdf_load_stackoverflow) | 1961-09-18 |
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