GB899596A - Sulphamyl-anilines and process for their manufacture - Google Patents

Sulphamyl-anilines and process for their manufacture

Info

Publication number
GB899596A
GB899596A GB4137059A GB4137059A GB899596A GB 899596 A GB899596 A GB 899596A GB 4137059 A GB4137059 A GB 4137059A GB 4137059 A GB4137059 A GB 4137059A GB 899596 A GB899596 A GB 899596A
Authority
GB
United Kingdom
Prior art keywords
halogen atom
lower alkyl
compounds
reacting
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4137059A
Inventor
George De Stevens
Lincoln Harvey Werner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Priority to GB4137059A priority Critical patent/GB899596A/en
Publication of GB899596A publication Critical patent/GB899596A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Abstract

The invention comprises compounds of the general formula <FORM:0899596/IV (b)/1> (wherein R1 represents a phenyl-lower alkyl radical, in which the phenyl group is unsubstituted or carries one or more lower alkyl, lower alkoxy, methylenedioxy or halogen substituents, R2 represents a halogen atom or a lower alkyl or trifluoromethyl group, X represents a halogen atom or an NH2 group, and the term "lower" denotes the presence of 1-3 carbon atoms) and the alkali metal salts of the compounds in which X is NH2, and the preparation of these compounds by reacting an aniline-2,4-disulphonyl halide of the general formula <FORM:0899596/IV (b)/2> (wherein Hal represents a halogen atom) with an approximately equimolecular proportion of an amine R1NH2 in the presence of an acidbinding condensing agent, and, if desired, reacting the product with ammonia, and further, if desired, converting a resulting free compound into an alkali metal salt or vice versa. The products in which X is NH2 have diuretic and sodiuretic properties.
GB4137059A 1959-12-04 1959-12-04 Sulphamyl-anilines and process for their manufacture Expired GB899596A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB4137059A GB899596A (en) 1959-12-04 1959-12-04 Sulphamyl-anilines and process for their manufacture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4137059A GB899596A (en) 1959-12-04 1959-12-04 Sulphamyl-anilines and process for their manufacture

Publications (1)

Publication Number Publication Date
GB899596A true GB899596A (en) 1962-06-27

Family

ID=10419372

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4137059A Expired GB899596A (en) 1959-12-04 1959-12-04 Sulphamyl-anilines and process for their manufacture

Country Status (1)

Country Link
GB (1) GB899596A (en)

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