GB876465A - New tertiary amines - Google Patents

New tertiary amines

Info

Publication number
GB876465A
GB876465A GB10947/60A GB1094760A GB876465A GB 876465 A GB876465 A GB 876465A GB 10947/60 A GB10947/60 A GB 10947/60A GB 1094760 A GB1094760 A GB 1094760A GB 876465 A GB876465 A GB 876465A
Authority
GB
United Kingdom
Prior art keywords
rch2c
butyl
prepared
ester
2nhch3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10947/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB876465A publication Critical patent/GB876465A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises amines of the general formula <FORM:0876465/IV (b)/1> and acid addition salts thereof wherein R is hydrogen or an alkyl radical containing 1-3 carbon atoms and R1 is a straight or branched alkyl radical containing at least 2 carbon atoms which may be substituted by hydroxyl radicals and/or phenyl radicals, together with the preparation thereof by reductive methylation of amines of the formula RCH2C(CH3)2NHR1. The compounds may also be prepared by alkylation of RCH2C(CH3)2NHCH3 with a reactive ester of R1OH or formation of the acyl or thioacyl derivative followed by reduction or methylation of RCH2C(CH3)2NHCH3 with a reactive methanol ester or formation of the formyl derivative followed by reduction. N.-t-Butylisopropylamine, N-tertbutylethylamine, and N-t-butyl-2-amino-pentane are prepared by reacting t-butyl-amine with isopropyl iodide, ethyl iodide or sec-amyl bromide. N-t-Butyl-2-aminopropanol is prepared by reacting a -bromopropionic acid ethyl ester with t-butylamine and reducing the a -(N-t-butylamine)-propionic acid ethyl ester so produced. Specification 873,780 is referred to.
GB10947/60A 1959-03-28 1960-03-28 New tertiary amines Expired GB876465A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE876465X 1959-03-28

Publications (1)

Publication Number Publication Date
GB876465A true GB876465A (en) 1961-09-06

Family

ID=6817706

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10947/60A Expired GB876465A (en) 1959-03-28 1960-03-28 New tertiary amines

Country Status (1)

Country Link
GB (1) GB876465A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3198705A (en) * 1963-01-14 1965-08-03 American Cyanamid Co Method of inducing hypotensive and ganglionic blocking activity
US3366688A (en) * 1962-10-22 1968-01-30 Lilly Co Eli Process for the preparation of alpha, alpha-disubstituted-gema-hydroxyamines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3366688A (en) * 1962-10-22 1968-01-30 Lilly Co Eli Process for the preparation of alpha, alpha-disubstituted-gema-hydroxyamines
US3198705A (en) * 1963-01-14 1965-08-03 American Cyanamid Co Method of inducing hypotensive and ganglionic blocking activity

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