GB871757A - Basically substituted diphenyl-carbinol-esters and a process for their manufacture - Google Patents
Basically substituted diphenyl-carbinol-esters and a process for their manufactureInfo
- Publication number
- GB871757A GB871757A GB23190/58A GB2319058A GB871757A GB 871757 A GB871757 A GB 871757A GB 23190/58 A GB23190/58 A GB 23190/58A GB 2319058 A GB2319058 A GB 2319058A GB 871757 A GB871757 A GB 871757A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- general formula
- methyl
- nitro
- acid addition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Natural products C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
- SLAMLWHELXOEJZ-UHFFFAOYSA-N 2-nitrobenzoic acid Chemical compound OC(=O)C1=CC=CC=C1[N+]([O-])=O SLAMLWHELXOEJZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- KRIOVPPHQSLHCZ-UHFFFAOYSA-N propiophenone Chemical class CCC(=O)C1=CC=CC=C1 KRIOVPPHQSLHCZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000007818 Grignard reagent Substances 0.000 abstract 1
- OKJIRPAQVSHGFK-UHFFFAOYSA-N N-acetylglycine Chemical class CC(=O)NCC(O)=O OKJIRPAQVSHGFK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- QILSFLSDHQAZET-UHFFFAOYSA-N diphenylmethanol Chemical class C=1C=CC=CC=1C(O)C1=CC=CC=C1 QILSFLSDHQAZET-UHFFFAOYSA-N 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000006196 drop Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004795 grignard reagents Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003151 propanoic acid esters Chemical class 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/02—Laboratory benches or tables; Fittings therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF23511A DE1111208B (de) | 1957-07-18 | 1957-07-18 | Verfahren zur Herstellung von hustenreizstillend wirkenden, basisch substituierten Diphenylcarbinolestern |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB871757A true GB871757A (en) | 1961-06-28 |
Family
ID=7090870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB23190/58A Expired GB871757A (en) | 1957-07-18 | 1958-07-18 | Basically substituted diphenyl-carbinol-esters and a process for their manufacture |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US2989533A (en, 2012) |
| BE (1) | BE569579A (en, 2012) |
| CH (1) | CH373058A (en, 2012) |
| DE (1) | DE1111208B (en, 2012) |
| FR (2) | FR1200359A (en, 2012) |
| GB (1) | GB871757A (en, 2012) |
| NL (1) | NL100012C (en, 2012) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB993525A (en) * | 1961-05-19 | 1965-05-26 | Smith Kline French Lab | Substituted propanolamines and process for preparing the same |
| AT255400B (de) * | 1965-03-22 | 1967-07-10 | Chemie Linz Ag | Verfahren zur Herstellung von neuen basischen Äthern |
| US3506670A (en) * | 1966-09-26 | 1970-04-14 | Upjohn Co | 2-hetero-amino-alpha,alpha-diaryl-cycloalkone-methanols and esters thereof |
| GB1237352A (en) * | 1969-01-03 | 1971-06-30 | Ct Europ De Rech S Mauvernay | Substituted propylamines |
| US3976653A (en) * | 1973-08-08 | 1976-08-24 | Sterling Drug Inc. | 3-Piperidine-methanols |
| US4022792A (en) * | 1974-12-16 | 1977-05-10 | Sterling Drug Inc. | Methylidenepiperidines |
| US4069256A (en) * | 1975-01-20 | 1978-01-17 | Sterling Drug Inc. | Anti-inflammatory phenyl-lower-alkylamines |
| US4031101A (en) * | 1976-04-15 | 1977-06-21 | Parke, Davis & Company | Cis-2,6-dimethyl-α,α-diphenyl-1-piperidinebutanol compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB683950A (en) * | 1949-07-18 | 1952-12-10 | Wellcome Found | Improvements in and relating to the manufacture of amino carbinols and alkenes |
| NL93401C (en, 2012) * | 1954-10-23 |
-
1957
- 1957-07-18 DE DEF23511A patent/DE1111208B/de active Pending
-
1958
- 1958-04-24 FR FR1200359D patent/FR1200359A/fr not_active Expired
- 1958-07-15 US US748585A patent/US2989533A/en not_active Expired - Lifetime
- 1958-07-16 CH CH6182858A patent/CH373058A/de unknown
- 1958-07-18 GB GB23190/58A patent/GB871757A/en not_active Expired
- 1958-07-18 NL NL229715A patent/NL100012C/xx active
- 1958-07-18 BE BE569579A patent/BE569579A/xx unknown
- 1958-07-18 FR FR1200539D patent/FR1200539A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1111208B (de) | 1961-07-20 |
| FR1200539A (fr) | 1959-12-22 |
| FR1200359A (fr) | 1959-12-21 |
| US2989533A (en) | 1961-06-20 |
| NL100012C (en, 2012) | 1961-12-15 |
| CH373058A (de) | 1963-11-15 |
| BE569579A (en, 2012) | 1959-01-19 |
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