GB8608020D0 - Compounds - Google Patents

Compounds

Info

Publication number
GB8608020D0
GB8608020D0 GB868608020A GB8608020A GB8608020D0 GB 8608020 D0 GB8608020 D0 GB 8608020D0 GB 868608020 A GB868608020 A GB 868608020A GB 8608020 A GB8608020 A GB 8608020A GB 8608020 D0 GB8608020 D0 GB 8608020D0
Authority
GB
United Kingdom
Prior art keywords
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB868608020A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB868608020A priority Critical patent/GB8608020D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of GB8608020D0 publication Critical patent/GB8608020D0/en
Priority to NZ219828A priority patent/NZ219828A/xx
Priority to ZA872334A priority patent/ZA872334B/xx
Priority to AU70905/87A priority patent/AU602681B2/en
Priority to PT84590A priority patent/PT84590B/pt
Priority to ES87302837T priority patent/ES2042553T3/es
Priority to DE8787302837T priority patent/DE3780199T2/de
Priority to DK165887A priority patent/DK165887A/da
Priority to EP87302837A priority patent/EP0241210B1/en
Priority to JP62080870A priority patent/JPS62289181A/ja
Priority to GR920401907T priority patent/GR3005571T3/el
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
GB868608020A 1986-04-02 1986-04-02 Compounds Pending GB8608020D0 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
GB868608020A GB8608020D0 (en) 1986-04-02 1986-04-02 Compounds
NZ219828A NZ219828A (en) 1986-04-02 1987-03-31 A t-pa modified by the addition of one or more finger domains
ZA872334A ZA872334B (en) 1986-04-02 1987-03-31 Modified enzyme
AU70905/87A AU602681B2 (en) 1986-04-02 1987-03-31 Modified plasminogen activators
PT84590A PT84590B (pt) 1986-04-02 1987-03-31 Processo para a preparacao de uma enzima fibrinolitica
ES87302837T ES2042553T3 (es) 1986-04-02 1987-04-01 Un proceso para la preparacion de un activador del plasminogeno fibrinoliticamente activo.
JP62080870A JPS62289181A (ja) 1986-04-02 1987-04-01 新規化合物、その製法およびそれを含む医薬組成物
DE8787302837T DE3780199T2 (de) 1986-04-02 1987-04-01 Modifiziertes enzym.
DK165887A DK165887A (da) 1986-04-02 1987-04-01 Modificeret fibrinolytisk enzym
EP87302837A EP0241210B1 (en) 1986-04-02 1987-04-01 Modified enzyme
GR920401907T GR3005571T3 (US07579456-20090825-P00002.png) 1986-04-02 1992-08-31

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868608020A GB8608020D0 (en) 1986-04-02 1986-04-02 Compounds

Publications (1)

Publication Number Publication Date
GB8608020D0 true GB8608020D0 (en) 1986-05-08

Family

ID=10595544

Family Applications (1)

Application Number Title Priority Date Filing Date
GB868608020A Pending GB8608020D0 (en) 1986-04-02 1986-04-02 Compounds

Country Status (11)

Country Link
EP (1) EP0241210B1 (US07579456-20090825-P00002.png)
JP (1) JPS62289181A (US07579456-20090825-P00002.png)
AU (1) AU602681B2 (US07579456-20090825-P00002.png)
DE (1) DE3780199T2 (US07579456-20090825-P00002.png)
DK (1) DK165887A (US07579456-20090825-P00002.png)
ES (1) ES2042553T3 (US07579456-20090825-P00002.png)
GB (1) GB8608020D0 (US07579456-20090825-P00002.png)
GR (1) GR3005571T3 (US07579456-20090825-P00002.png)
NZ (1) NZ219828A (US07579456-20090825-P00002.png)
PT (1) PT84590B (US07579456-20090825-P00002.png)
ZA (1) ZA872334B (US07579456-20090825-P00002.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1295088A (en) * 1987-01-30 1988-08-24 American Home Products Corporation Des-epidermal growth factor plasminogen activators
FI882407A (fi) * 1987-05-22 1988-11-23 Zymogenetics Inc Fibrinolytiska proteiner.
SE8702562L (sv) * 1987-06-18 1988-12-19 Kabigen Ab Nya fibrinolytiska enzymer
EP0340573A3 (de) * 1988-04-30 1990-05-30 BASF Aktiengesellschaft Neue Proteine, ihre Herstellung und Verwendung
DE3836200A1 (de) * 1988-10-24 1990-04-26 Boehringer Mannheim Gmbh Domaenenduplikations-muteine des gewebsplasminogen-aktivators (t-pa)
DE4123845A1 (de) * 1991-07-18 1993-01-21 Boehringer Mannheim Gmbh Pharmazeutische verpackungseinheit enthaltend plasminogenaktivatoren zur mehrfachbolusgabe
AT409379B (de) * 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
AU7090787A (en) * 1986-02-19 1987-10-08 Beecham Group Plc Tissue plasminogen activator
AU7090687A (en) * 1986-04-02 1987-10-08 Beecham Group Plc Modified tissue-type plasminogen activators
AU7090887A (en) * 1986-04-02 1987-10-08 Beecham Group Plc Plasminogen activators modified in first kringle domain

Also Published As

Publication number Publication date
JPS62289181A (ja) 1987-12-16
DE3780199T2 (de) 1993-01-21
NZ219828A (en) 1990-08-28
ZA872334B (en) 1987-12-30
AU7090587A (en) 1987-10-08
DE3780199D1 (de) 1992-08-13
DK165887D0 (da) 1987-04-01
PT84590A (en) 1987-04-01
EP0241210B1 (en) 1992-07-08
PT84590B (pt) 1989-11-30
EP0241210A1 (en) 1987-10-14
ES2042553T3 (es) 1993-12-16
DK165887A (da) 1987-10-02
AU602681B2 (en) 1990-10-25
GR3005571T3 (US07579456-20090825-P00002.png) 1993-06-07

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