Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB27980/57A
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BASF Schweiz AG
Original Assignee
Ciba AG
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Publication date
Application filed by Ciba AGfiledCriticalCiba AG
Publication of GB846030ApublicationCriticalpatent/GB846030A/en
C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
C07D209/44—Iso-indoles; Hydrogenated iso-indoles
C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07D—HETEROCYCLIC COMPOUNDS
C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
C07D209/44—Iso-indoles; Hydrogenated iso-indoles
C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
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Chemical & Material Sciences
(AREA)
Organic Chemistry
(AREA)
Indole Compounds
(AREA)
Abstract
Dimethochlorides of 2-tertiary amino-alkyl-tetrachloroisoindolines (wherein the alkyl residue has at most 3 carbon atoms and the tertiary amino group is a dialkylamino group wherein the alkyl radicals each contain at most 5 carbon atoms or a saturated nitrogen containing heterocyclic radial of 4 or 5 carbon atoms which may contain oxygen or additional nitrogen atoms as chain members) are prepared by treating a solution of a 2-tertiary amino-alkyl-tetrachloroisoindoline or its monomethochloride in formamide in a closed vessel with an excess of methyl chloride at about 50 to 200 DEG C. The excess of methyl chloride is desirably at least 50% and most preferably 250%. Examples describe the preparation of 4:5:6:7-tetrachloro-2-(21-dimethylamino-ethyl)-isoindoline dimethochloride and the corresponding diethylamino compound.
GB27980/57A1956-09-041957-09-04Preparation of bis-quaternary ammonium compounds
ExpiredGB846030A
(en)
A method of conservation of a material normally subjected to the attack of fungi and bacteria (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of new derivatives of heterocyclic hydrazines and their salts (Machine-translation by Google Translate, not legally binding)
Improvements introduced in patent number 232318, procedure for the obtaining of new amidas of alpha - amino - beta - oxicarboxylic acids (Machine-translation by Google Translate, not legally binding)
Procedure for preparing derivatives of 9-10-dihydro-4h-benzo (4,5) ciclohepta (2,1-b) thiophene. (Machine-translation by Google Translate, not legally binding)