GB820268A - Preparation of lysine - Google Patents

Preparation of lysine

Info

Publication number
GB820268A
GB820268A GB16456/58A GB1645658A GB820268A GB 820268 A GB820268 A GB 820268A GB 16456/58 A GB16456/58 A GB 16456/58A GB 1645658 A GB1645658 A GB 1645658A GB 820268 A GB820268 A GB 820268A
Authority
GB
United Kingdom
Prior art keywords
lysine
diaminopimelic acid
enzyme
prepared
aerobacter aerogenes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB16456/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB820268A publication Critical patent/GB820268A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Lysine is prepared by contacting diaminopimelic acid with the enzyme diaminopimelic acid decarboxylase produced by Aerobacter aerogenes or a strain of Escherichia coli which does not require lysine for its growth and which lacks lysine decarboxylase. A suitable microorganism is Aerobacter aerogenes ATCC 12,409. Suitably the reaction mixture is maintained at about 28 DEG C. at about a neutral pH for approximately 24 hours. The enzyme may be liberated from the organism cells by standard methods, preferably by treatment with toluene, which need not be removed before the contact with diaminopimelic acid. The latter may be present in a fermented broth, such as is prepared in Specification 820,267.
GB16456/58A 1955-12-09 1956-10-26 Preparation of lysine Expired GB820268A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US820268XA 1955-12-09 1955-12-09

Publications (1)

Publication Number Publication Date
GB820268A true GB820268A (en) 1959-09-16

Family

ID=22168572

Family Applications (1)

Application Number Title Priority Date Filing Date
GB16456/58A Expired GB820268A (en) 1955-12-09 1956-10-26 Preparation of lysine

Country Status (1)

Country Link
GB (1) GB820268A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0796912A1 (en) * 1994-12-09 1997-09-24 Ajinomoto Co., Inc. Novel lysine decarboxylase gene and process for producing l-lysine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0796912A1 (en) * 1994-12-09 1997-09-24 Ajinomoto Co., Inc. Novel lysine decarboxylase gene and process for producing l-lysine
EP0796912A4 (en) * 1994-12-09 2001-03-21 Ajinomoto Kk Novel lysine decarboxylase gene and process for producing l-lysine

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