GB811688A - Method for purification of glutamic acid - Google Patents

Method for purification of glutamic acid

Info

Publication number
GB811688A
GB811688A GB9030/57A GB903057A GB811688A GB 811688 A GB811688 A GB 811688A GB 9030/57 A GB9030/57 A GB 9030/57A GB 903057 A GB903057 A GB 903057A GB 811688 A GB811688 A GB 811688A
Authority
GB
United Kingdom
Prior art keywords
glutamic acid
amberlite
resin
resins
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9030/57A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of GB811688A publication Critical patent/GB811688A/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00—Ion-exchange processes in general; Apparatus therefor
    • B01J47/014—Ion-exchange processes in general; Apparatus therefor in which the adsorbent properties of the ion-exchanger are involved, e.g. recovery of proteins or other high-molecular compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Glutamic acid is separated and concentrated from an aqueous liquid also containing other amino acids by passing the liquid through a column packed with a strongly acidic cation exchange resin and through a column packed with an anion exchange resin, treating the glutamic acid-rich fraction so obtained with a weakly basic anion exchange resin, and eluting the glutamic acid adsorbed on the resin with an acid solution. The first two resins may be used in any order, or together as a mixture; when the liquid contains a high proportion of glutamic acid as compared with other amino acids, it is preferable to pass it through a mixture of the first two resins. Suitable starting solutions are Steffen's waste and a fermented broth. Suitable strongly acidic cation exchange resins are "Amberlite" IR-120, Dowex 50, Chempro C-20, "Permutit" Q and Diaion SK 1; suitable anion exchange resins are "Amberlite" IRA-400, "Amberlite" IR-4B, "Amberlite" IR-45, Dowex 1, Duolite A-42 and Diaion SK 100; suitable weakly basic anion exchange resins are "Amberlite" IR-4B and "Amberlite" IR-45 ("Amberlite" and "Permutit" are Registered Trade Marks). The liquid is passed through the first resin to obtain a glutamic acid-rich fraction of the effluent, which is passed through the second resin to obtain a more concentrated glutamic acid-rich fraction (or the liquid is passed through the mixture of the first two resins to obtain a single concentrated fraction), and the latter passed through the third resin. The adsorbed glutamic acid may then be eluted with 1-5 n NCl, and crystallized out by adjusting the pH to 3.2. The overall concentration is about 10 : 1. Examples of the process are given.
GB9030/57A 1956-07-19 1957-03-19 Method for purification of glutamic acid Expired GB811688A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP359445X 1956-07-19

Publications (1)

Publication Number Publication Date
GB811688A true GB811688A (en) 1959-04-08

Family

ID=12456093

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9030/57A Expired GB811688A (en) 1956-07-19 1957-03-19 Method for purification of glutamic acid

Country Status (3)

Country Link
CH (1) CH359445A (en)
DE (1) DE1088975B (en)
GB (1) GB811688A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147259A (en) * 1996-01-22 2000-11-14 Amylum N.V. Process for producing glutamic acid

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1001068A (en) * 1961-07-14 1965-08-11 Nippon Kayaku Kk Method for producing methionine-methylsulfonium salts
US3336374A (en) * 1963-02-15 1967-08-15 Int Minerals & Chem Corp Recovery of l-glutamic acid
US3331828A (en) * 1964-09-30 1967-07-18 Merck & Co Inc Isolation of gamma-l-glutamyl dipeptides from glutamic acid fermentation broths by ion exchange

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528047A (en) * 1947-12-09 1950-10-31 Dorr Co Recovery of glutamic compounds from glutamine contained in an impure solution thereof
FR1063701A (en) * 1952-09-27 1954-05-05 Process for extracting glutamic acid from proteins containing a high proportion of starch
DE950556C (en) * 1953-01-30 1956-10-11 Centrale Suiker Mij Nv Process for the production of nitrogen compounds from molasses

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147259A (en) * 1996-01-22 2000-11-14 Amylum N.V. Process for producing glutamic acid

Also Published As

Publication number Publication date
DE1088975B (en) 1960-09-15
CH359445A (en) 1962-01-15

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