GB770263A - Process for the manufacture of acetoacetamides - Google Patents
Process for the manufacture of acetoacetamidesInfo
- Publication number
- GB770263A GB770263A GB17632/55A GB1763255A GB770263A GB 770263 A GB770263 A GB 770263A GB 17632/55 A GB17632/55 A GB 17632/55A GB 1763255 A GB1763255 A GB 1763255A GB 770263 A GB770263 A GB 770263A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aniline
- diketene
- solution
- water
- reacted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Aryl acetoacetamides are prepared by reacting water-insoluble aromatic primary amines with diketene at ordinary or moderately raised temperatures, the amino-compound being used in the form of a salt thereof with an organic or inorganic acid, the salt being dissolved in water, if desired. The reaction may be carried out by adding diketone gradually to an aqueous solution of amine salt or to a solution of the amine in a liquid acid such as acetic acid. The acetoacetamide separates during the reaction and may be removed by filtration, the mother liquor being re-used, if desired. Specified amines are aniline, o-toluidine, and o-chloroaniline. Specified acids are acetic, hydrochloric and sulphuric acids. In examples: (1) diketene is added slowly to a solution of aniline in aqueous acetic acid, the temperature being maintained at about 45 DEG C., the solution is cooled and the crystalline acetoacetanilide removed by filtration; (2) part of a batch of aniline is dissolved in a slight excess of acetic acid diluted with water and reacted with diketene as in (1), further aniline is added to the reaction mixture and reacted with diketene, the process being continued until the whole batch of aniline has been reacted; (3) as in (2) but not adding water.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE770263X | 1954-06-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB770263A true GB770263A (en) | 1957-03-20 |
Family
ID=6674897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB17632/55A Expired GB770263A (en) | 1954-06-19 | 1955-06-17 | Process for the manufacture of acetoacetamides |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB770263A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2518922A1 (en) * | 1975-04-29 | 1976-11-18 | Hoechst Ag | PROCESS FOR THE PREPARATION OF 5-ACETOACETYLAMINOBENZIMIDAZOLONE |
| DE2612391A1 (en) * | 1976-03-24 | 1977-10-06 | Hoechst Ag | PROCESS FOR THE PREPARATION OF 5-ACETOACETYLAMINOBENZIMIDAZOLONE |
-
1955
- 1955-06-17 GB GB17632/55A patent/GB770263A/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2518922A1 (en) * | 1975-04-29 | 1976-11-18 | Hoechst Ag | PROCESS FOR THE PREPARATION OF 5-ACETOACETYLAMINOBENZIMIDAZOLONE |
| US4087610A (en) * | 1975-04-29 | 1978-05-02 | Hoechst Aktiengesellschaft | Process for the preparation of 5-acetoacetylamino-benzimidazolone |
| DE2612391A1 (en) * | 1976-03-24 | 1977-10-06 | Hoechst Ag | PROCESS FOR THE PREPARATION OF 5-ACETOACETYLAMINOBENZIMIDAZOLONE |
| US4153798A (en) * | 1976-03-24 | 1979-05-08 | Hoechst Aktiengesellschaft | Process for the manufacture of 5-acetoacetylamino-benzimidazolone |
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