GB743160A - Steroids - Google Patents
SteroidsInfo
- Publication number
- GB743160A GB743160A GB29101/53A GB2910153A GB743160A GB 743160 A GB743160 A GB 743160A GB 29101/53 A GB29101/53 A GB 29101/53A GB 2910153 A GB2910153 A GB 2910153A GB 743160 A GB743160 A GB 743160A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroid
- acid
- dione
- hydroxy
- pregnane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises a steroid-lacto-enol acylate having at carbon atom 17 of the steroid nucleus the substituent represented by the following formula: <FORM:0743160/IV(a)/1> wherein Ac represents the acyl radical of a hydrocarbon carboxylic acid having from one to eight carbon atoms, inclusive, and the preparation thereof by reacting a steroid having at position 17 the structure <FORM:0743160/IV(a)/2> with an acylating agent, e.g. organic carboxylic acid anhydrides, formic acid, ketene or isopropenyl acylate. The reaction may be effected between 20 degrees centigrade and the boiling point of the reaction mixture. Examples utilize as starting materials 3(a or b )-hydroxy-pregnane - 11,20 - dione - 21 - glyoxalic acid, 3a , 11(a or b )-dihydroxy pregnane-20-one-21-glyoxalic acid, 11(a or b )-hydroxy- or 11-keto-progesterone and 11(a or b )-hydroxypregnane-3,20 - dione - 21 - glyoxalic acid. Specifications 724,163, 733,448, 733,449 and 738,445 are referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US743160XA | 1952-10-24 | 1952-10-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB743160A true GB743160A (en) | 1956-01-11 |
Family
ID=22118925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB29101/53A Expired GB743160A (en) | 1952-10-24 | 1953-10-21 | Steroids |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB743160A (en) |
-
1953
- 1953-10-21 GB GB29101/53A patent/GB743160A/en not_active Expired
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