GB731706A - Preparation of vitamin b-12 - Google Patents
Preparation of vitamin b-12Info
- Publication number
- GB731706A GB731706A GB28009/52A GB2800952A GB731706A GB 731706 A GB731706 A GB 731706A GB 28009/52 A GB28009/52 A GB 28009/52A GB 2800952 A GB2800952 A GB 2800952A GB 731706 A GB731706 A GB 731706A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vitamin
- atcc
- carbon
- fermentation
- fat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/42—Cobalamins, i.e. vitamin B12, LLD factor
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Vitamin B12 is obtained by growing a microorganism of the class consisting of Actinomycete ATCC No. 11071 and Mutant ATCC No. 11072, in a suitable sterile, aqueous, nutrient medium containing assimilable sources of carbon, nitrogen and cobalt, whereby fermentation results with the production of Vitamin B12 which is recovered. Prior to the recovery of Vitamin B12 the broth is subjected to cell rupture, e.g. by treatment with sonic waves. The fermentation may be carried out in the temperature range 30 DEG C. to 37 DEG C. and the yield of cobalamine enhanced by the addition of cyanide ion or nitrile. The carbon source consists, at least in part, of (1) a fat or (2) a fat acid having more than 14 carbon atoms in the molecule.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US731706XA | 1951-11-07 | 1951-11-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB731706A true GB731706A (en) | 1955-06-15 |
Family
ID=22112148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28009/52A Expired GB731706A (en) | 1951-11-07 | 1952-11-06 | Preparation of vitamin b-12 |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB731706A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2971891A (en) * | 1959-04-08 | 1961-02-14 | Olin Mathieson | Preparation of cyanocobalamins |
-
1952
- 1952-11-06 GB GB28009/52A patent/GB731706A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2971891A (en) * | 1959-04-08 | 1961-02-14 | Olin Mathieson | Preparation of cyanocobalamins |
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