GB713779A - Improvements in or relating to choline chloride compositions and feed compositions containing said choline chloride compositions - Google Patents
Improvements in or relating to choline chloride compositions and feed compositions containing said choline chloride compositionsInfo
- Publication number
- GB713779A GB713779A GB29592/51A GB2959251A GB713779A GB 713779 A GB713779 A GB 713779A GB 29592/51 A GB29592/51 A GB 29592/51A GB 2959251 A GB2959251 A GB 2959251A GB 713779 A GB713779 A GB 713779A
- Authority
- GB
- United Kingdom
- Prior art keywords
- choline
- choline chloride
- composition
- mols
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 title abstract 6
- 235000019743 Choline chloride Nutrition 0.000 title abstract 6
- 229960003178 choline chloride Drugs 0.000 title abstract 6
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 title abstract 6
- 229960001231 choline Drugs 0.000 abstract 5
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 abstract 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 3
- -1 ferrous metals Chemical class 0.000 abstract 3
- 229950004354 phosphorylcholine Drugs 0.000 abstract 3
- PYJNAPOPMIJKJZ-UHFFFAOYSA-N phosphorylcholine chloride Chemical compound [Cl-].C[N+](C)(C)CCOP(O)(O)=O PYJNAPOPMIJKJZ-UHFFFAOYSA-N 0.000 abstract 3
- CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Substances [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 238000002845 discoloration Methods 0.000 abstract 2
- 235000011167 hydrochloric acid Nutrition 0.000 abstract 2
- 229910052751 metal Inorganic materials 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 abstract 1
- 230000037213 diet Effects 0.000 abstract 1
- 235000005911 diet Nutrition 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 150000004712 monophosphates Chemical class 0.000 abstract 1
- 235000011007 phosphoric acid Nutrition 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A composition comprises choline chloride and an amount of choline phosphate sufficient to inhibit discoloration of the composition in contact with ferrous metals. There is described the preparation of a solution of the salts in the ratio 99-60 mols. of choline chloride to 1-40 mols. of choline phosphate calculated as the monophosphate by the treatment of an aqueous solution of choline with sufficient phosphoric and hydrochloric acid to provide pH 5.0-6.8 and then adjusting the pH to 7-8 by addition of sodium bicarbonate or carbonate.ALSO:A composition comprising choline chloride and an amount of choline phosphate sufficient to inhibit discoloration of the composition in contact with ferrous metals is incorporated into animal feed in quantity sufficient to provide 0.05-4 per cent of choline. A preparation which contains the salts in the ratio of 99-60 mols of choline chloride to 1-40 mols of choline monophosphate is obtained by treatment of an aqueous solution of choline with phosphoric and hydrochloric acids to produce pH 5.0-6.8, adjusting the solution to pH 7-8 by addition of sodium carbonate or bicarbonate, and concentrating at 40-65 DEG C. in vacuo to 70 per cent choline solids. An example is concerned with prevention of perosis in chicks by incorporation of such a preparation into a choline-free diet, the composition of which is set forth in detail.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US713779XA | 1950-12-29 | 1950-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB713779A true GB713779A (en) | 1954-08-18 |
Family
ID=22100918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB29592/51A Expired GB713779A (en) | 1950-12-29 | 1951-12-18 | Improvements in or relating to choline chloride compositions and feed compositions containing said choline chloride compositions |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB713779A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004000292A1 (en) * | 2002-06-21 | 2003-12-31 | Basf Aktiengesellschaft | Composition comprising stabilised choline ascorbate |
-
1951
- 1951-12-18 GB GB29592/51A patent/GB713779A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004000292A1 (en) * | 2002-06-21 | 2003-12-31 | Basf Aktiengesellschaft | Composition comprising stabilised choline ascorbate |
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