GB668494A - Water-soluble derivatives of stilboestrol and process for the manufacture thereof - Google Patents

Water-soluble derivatives of stilboestrol and process for the manufacture thereof

Info

Publication number
GB668494A
GB668494A GB2851/50A GB285150A GB668494A GB 668494 A GB668494 A GB 668494A GB 2851/50 A GB2851/50 A GB 2851/50A GB 285150 A GB285150 A GB 285150A GB 668494 A GB668494 A GB 668494A
Authority
GB
United Kingdom
Prior art keywords
stilboestrol
water
soluble derivatives
diethylstilboestrol
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2851/50A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Products Ltd
Original Assignee
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Products Ltd filed Critical Roche Products Ltd
Publication of GB668494A publication Critical patent/GB668494A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/17Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing carboxyl groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Water - soluble derivatives of diethylstilboestrol are obtained by reacting sulpho-acetyl chloride with diethylstilboestrol in the presence of pyridine and, if necessary, treating the dipyridinium salt of the diethyl stilboestrol-di-(sulphoacetate) so formed with an alkali-metal or organic base so as to produce a salt of the said diethylstilboestrol-di-(sulphoacetate) with said base. As alkali metal base sodium hydroxide may be used. Specification 577,666 is referred to.
GB2851/50A 1949-02-04 1950-02-03 Water-soluble derivatives of stilboestrol and process for the manufacture thereof Expired GB668494A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH668494X 1949-02-04

Publications (1)

Publication Number Publication Date
GB668494A true GB668494A (en) 1952-03-19

Family

ID=4527473

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2851/50A Expired GB668494A (en) 1949-02-04 1950-02-03 Water-soluble derivatives of stilboestrol and process for the manufacture thereof

Country Status (1)

Country Link
GB (1) GB668494A (en)

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