GB627280A - Improvements in and relating to the preparation of a new ketone having analgesic properties - Google Patents
Improvements in and relating to the preparation of a new ketone having analgesic propertiesInfo
- Publication number
- GB627280A GB627280A GB5704/47A GB570447A GB627280A GB 627280 A GB627280 A GB 627280A GB 5704/47 A GB5704/47 A GB 5704/47A GB 570447 A GB570447 A GB 570447A GB 627280 A GB627280 A GB 627280A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diphenyl
- morpholino
- valeronitrile
- ketone
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002576 ketones Chemical class 0.000 title abstract 5
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- 239000004305 biphenyl Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- NEBPTMCRLHKPOB-UHFFFAOYSA-N 2,2-diphenylacetonitrile Chemical class C=1C=CC=CC=1C(C#N)C1=CC=CC=C1 NEBPTMCRLHKPOB-UHFFFAOYSA-N 0.000 abstract 2
- CDKFWIMBZAUBRS-UHFFFAOYSA-M [I-].CC[Mg+] Chemical compound [I-].CC[Mg+] CDKFWIMBZAUBRS-UHFFFAOYSA-M 0.000 abstract 2
- 150000002825 nitriles Chemical class 0.000 abstract 2
- YMHXXJJTAGKFBA-UHFFFAOYSA-N 1-bromo-2-chloropropane Chemical compound CC(Cl)CBr YMHXXJJTAGKFBA-UHFFFAOYSA-N 0.000 abstract 1
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 abstract 1
- 238000003747 Grignard reaction Methods 0.000 abstract 1
- 239000007818 Grignard reagent Substances 0.000 abstract 1
- RFFFKMOABOFIDF-UHFFFAOYSA-N Pentanenitrile Chemical compound CCCCC#N RFFFKMOABOFIDF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010290 biphenyl Nutrition 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- -1 ethyl magnesium halide Chemical class 0.000 abstract 1
- 150000004795 grignard reagents Chemical class 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5704/47A GB627280A (en) | 1947-02-27 | 1947-02-27 | Improvements in and relating to the preparation of a new ketone having analgesic properties |
US8738A US2513173A (en) | 1947-02-27 | 1948-02-16 | 4, 4-diphenyl-6-morpholino-heptanone-3 and acid salts thereof |
BE480545D BE480545A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1947-02-27 | 1948-02-21 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5704/47A GB627280A (en) | 1947-02-27 | 1947-02-27 | Improvements in and relating to the preparation of a new ketone having analgesic properties |
Publications (1)
Publication Number | Publication Date |
---|---|
GB627280A true GB627280A (en) | 1949-08-04 |
Family
ID=9801066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5704/47A Expired GB627280A (en) | 1947-02-27 | 1947-02-27 | Improvements in and relating to the preparation of a new ketone having analgesic properties |
Country Status (3)
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2763657A (en) * | 1952-10-31 | 1956-09-18 | Eastman Kodak Co | Aminomethyl-substituted aroylresorcinols |
-
1947
- 1947-02-27 GB GB5704/47A patent/GB627280A/en not_active Expired
-
1948
- 1948-02-16 US US8738A patent/US2513173A/en not_active Expired - Lifetime
- 1948-02-21 BE BE480545D patent/BE480545A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
BE480545A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1948-03-15 |
US2513173A (en) | 1950-06-27 |
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