GB496801A - Process for the manufacture of ethers of 2-methyl-2-hydroxy-3-chloro-tetrahydrofurane - Google Patents

Process for the manufacture of ethers of 2-methyl-2-hydroxy-3-chloro-tetrahydrofurane

Info

Publication number
GB496801A
GB496801A GB14292/38A GB1429238A GB496801A GB 496801 A GB496801 A GB 496801A GB 14292/38 A GB14292/38 A GB 14292/38A GB 1429238 A GB1429238 A GB 1429238A GB 496801 A GB496801 A GB 496801A
Authority
GB
United Kingdom
Prior art keywords
methyl
hydroxy
ethers
tetrahydrofurane
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB14292/38A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB496801A publication Critical patent/GB496801A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Alkyl ethers of 2-methyl-2-hydroxy-3-chlorotetrahydrofurane are prepared by treating a -aceto-a -chlorobutyrolactone with sulphuric acid and a primary aliphatic alcohol at a moderate temperature, preferably at 40-50 DEG C. Examples are given in which the methyl, ethyl and butyl ethers of 2-methyl-2-hydroxy-3-chlorotetrahydrofurane are prepared by treating a -aceto-a -chlorobutyrolactone with sulphuric acid and methanol, ethanol and n-butanol, respectively.
GB14292/38A 1937-07-20 1938-05-13 Process for the manufacture of ethers of 2-methyl-2-hydroxy-3-chloro-tetrahydrofurane Expired GB496801A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH496801X 1937-07-20

Publications (1)

Publication Number Publication Date
GB496801A true GB496801A (en) 1938-12-06

Family

ID=4516770

Family Applications (1)

Application Number Title Priority Date Filing Date
GB14292/38A Expired GB496801A (en) 1937-07-20 1938-05-13 Process for the manufacture of ethers of 2-methyl-2-hydroxy-3-chloro-tetrahydrofurane

Country Status (1)

Country Link
GB (1) GB496801A (en)

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