GB473064A - A process for the production of anti-anaemic preparations - Google Patents

A process for the production of anti-anaemic preparations

Info

Publication number
GB473064A
GB473064A GB671736A GB671736A GB473064A GB 473064 A GB473064 A GB 473064A GB 671736 A GB671736 A GB 671736A GB 671736 A GB671736 A GB 671736A GB 473064 A GB473064 A GB 473064A
Authority
GB
United Kingdom
Prior art keywords
fuller
preparations
earth
mixture
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB671736A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB671736A priority Critical patent/GB473064A/en
Publication of GB473064A publication Critical patent/GB473064A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Anti-anaemia preparations are obtained by treatment of crude aqueous or alcoholic extracts with an adsorbing agent in a neutral or slightly acid medium and separation of the active substance from the adsorbate by treatment with a dilute alkaline solution. Suitable adsorbents are fuller's earth, bentonite, silica gell, active charcoal. According to an example minced liver is extracted with water and 10 ccs. of concentrated hydrochloric acid and 40 grams of fuller's earth are added for each litre of filtrate. The adsorbent is separated, washed and suspended in a mixture of water, pyridine and methylalcohol. The mixture is filtered and concentrated at a low temperature, residual pyridine being removed by ether, and the extract-reconcentrated. Protein substances may be removed from the product by the addition of alcohol, filtering and reconcentrating.
GB671736A 1936-03-05 1936-03-05 A process for the production of anti-anaemic preparations Expired GB473064A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB671736A GB473064A (en) 1936-03-05 1936-03-05 A process for the production of anti-anaemic preparations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB671736A GB473064A (en) 1936-03-05 1936-03-05 A process for the production of anti-anaemic preparations

Publications (1)

Publication Number Publication Date
GB473064A true GB473064A (en) 1937-10-05

Family

ID=9819495

Family Applications (1)

Application Number Title Priority Date Filing Date
GB671736A Expired GB473064A (en) 1936-03-05 1936-03-05 A process for the production of anti-anaemic preparations

Country Status (1)

Country Link
GB (1) GB473064A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE745383C (en) * 1942-02-15 1944-12-01 Schering Ag Process for obtaining the antipernicious agent of the liver and a new activator of this agent
US2573702A (en) * 1948-04-09 1951-11-06 Merck & Co Inc Alumina chromatographic purification of liver extracts
US2609325A (en) * 1948-04-03 1952-09-02 Merck & Co Inc Recovery of vitamin b12 from liver
US2626888A (en) * 1950-09-07 1953-01-27 Merck & Co Inc Vitamin b12-active substance elution from monmorillonite absorbents
US2643210A (en) * 1950-09-07 1953-06-23 Merck & Co Inc Vitamin b12-active substance elution from montmorillonite absorbent
US2678297A (en) * 1951-02-16 1954-05-11 American Cyanamid Co Preparation of vitamin b12 concentrates
US2695862A (en) * 1949-08-04 1954-11-30 Merck & Co Inc Process for obtaining vitamin b12

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE745383C (en) * 1942-02-15 1944-12-01 Schering Ag Process for obtaining the antipernicious agent of the liver and a new activator of this agent
US2609325A (en) * 1948-04-03 1952-09-02 Merck & Co Inc Recovery of vitamin b12 from liver
US2573702A (en) * 1948-04-09 1951-11-06 Merck & Co Inc Alumina chromatographic purification of liver extracts
US2695862A (en) * 1949-08-04 1954-11-30 Merck & Co Inc Process for obtaining vitamin b12
US2626888A (en) * 1950-09-07 1953-01-27 Merck & Co Inc Vitamin b12-active substance elution from monmorillonite absorbents
US2643210A (en) * 1950-09-07 1953-06-23 Merck & Co Inc Vitamin b12-active substance elution from montmorillonite absorbent
US2678297A (en) * 1951-02-16 1954-05-11 American Cyanamid Co Preparation of vitamin b12 concentrates

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