GB473064A - A process for the production of anti-anaemic preparations - Google Patents
A process for the production of anti-anaemic preparationsInfo
- Publication number
- GB473064A GB473064A GB671736A GB671736A GB473064A GB 473064 A GB473064 A GB 473064A GB 671736 A GB671736 A GB 671736A GB 671736 A GB671736 A GB 671736A GB 473064 A GB473064 A GB 473064A
- Authority
- GB
- United Kingdom
- Prior art keywords
- fuller
- preparations
- earth
- mixture
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Anti-anaemia preparations are obtained by treatment of crude aqueous or alcoholic extracts with an adsorbing agent in a neutral or slightly acid medium and separation of the active substance from the adsorbate by treatment with a dilute alkaline solution. Suitable adsorbents are fuller's earth, bentonite, silica gell, active charcoal. According to an example minced liver is extracted with water and 10 ccs. of concentrated hydrochloric acid and 40 grams of fuller's earth are added for each litre of filtrate. The adsorbent is separated, washed and suspended in a mixture of water, pyridine and methylalcohol. The mixture is filtered and concentrated at a low temperature, residual pyridine being removed by ether, and the extract-reconcentrated. Protein substances may be removed from the product by the addition of alcohol, filtering and reconcentrating.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB671736A GB473064A (en) | 1936-03-05 | 1936-03-05 | A process for the production of anti-anaemic preparations |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB671736A GB473064A (en) | 1936-03-05 | 1936-03-05 | A process for the production of anti-anaemic preparations |
Publications (1)
Publication Number | Publication Date |
---|---|
GB473064A true GB473064A (en) | 1937-10-05 |
Family
ID=9819495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB671736A Expired GB473064A (en) | 1936-03-05 | 1936-03-05 | A process for the production of anti-anaemic preparations |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB473064A (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE745383C (en) * | 1942-02-15 | 1944-12-01 | Schering Ag | Process for obtaining the antipernicious agent of the liver and a new activator of this agent |
US2573702A (en) * | 1948-04-09 | 1951-11-06 | Merck & Co Inc | Alumina chromatographic purification of liver extracts |
US2609325A (en) * | 1948-04-03 | 1952-09-02 | Merck & Co Inc | Recovery of vitamin b12 from liver |
US2626888A (en) * | 1950-09-07 | 1953-01-27 | Merck & Co Inc | Vitamin b12-active substance elution from monmorillonite absorbents |
US2643210A (en) * | 1950-09-07 | 1953-06-23 | Merck & Co Inc | Vitamin b12-active substance elution from montmorillonite absorbent |
US2678297A (en) * | 1951-02-16 | 1954-05-11 | American Cyanamid Co | Preparation of vitamin b12 concentrates |
US2695862A (en) * | 1949-08-04 | 1954-11-30 | Merck & Co Inc | Process for obtaining vitamin b12 |
-
1936
- 1936-03-05 GB GB671736A patent/GB473064A/en not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE745383C (en) * | 1942-02-15 | 1944-12-01 | Schering Ag | Process for obtaining the antipernicious agent of the liver and a new activator of this agent |
US2609325A (en) * | 1948-04-03 | 1952-09-02 | Merck & Co Inc | Recovery of vitamin b12 from liver |
US2573702A (en) * | 1948-04-09 | 1951-11-06 | Merck & Co Inc | Alumina chromatographic purification of liver extracts |
US2695862A (en) * | 1949-08-04 | 1954-11-30 | Merck & Co Inc | Process for obtaining vitamin b12 |
US2626888A (en) * | 1950-09-07 | 1953-01-27 | Merck & Co Inc | Vitamin b12-active substance elution from monmorillonite absorbents |
US2643210A (en) * | 1950-09-07 | 1953-06-23 | Merck & Co Inc | Vitamin b12-active substance elution from montmorillonite absorbent |
US2678297A (en) * | 1951-02-16 | 1954-05-11 | American Cyanamid Co | Preparation of vitamin b12 concentrates |
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