GB2612617A - Demineralisation of organic tissue - Google Patents
Demineralisation of organic tissue Download PDFInfo
- Publication number
- GB2612617A GB2612617A GB2115923.1A GB202115923A GB2612617A GB 2612617 A GB2612617 A GB 2612617A GB 202115923 A GB202115923 A GB 202115923A GB 2612617 A GB2612617 A GB 2612617A
- Authority
- GB
- United Kingdom
- Prior art keywords
- drum
- mineralised
- tissue remnants
- remnants
- reaction vessel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000005115 demineralization Methods 0.000 title claims description 92
- 238000006243 chemical reaction Methods 0.000 claims abstract description 181
- 238000000034 method Methods 0.000 claims abstract description 173
- 239000002253 acid Substances 0.000 claims abstract description 129
- 238000012545 processing Methods 0.000 claims abstract description 107
- 238000006460 hydrolysis reaction Methods 0.000 claims abstract description 103
- 238000002156 mixing Methods 0.000 claims abstract description 102
- 230000007062 hydrolysis Effects 0.000 claims abstract description 97
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 claims abstract description 74
- 230000007071 enzymatic hydrolysis Effects 0.000 claims abstract description 72
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 70
- 239000011707 mineral Substances 0.000 claims abstract description 70
- 239000000463 material Substances 0.000 claims description 146
- 102000004169 proteins and genes Human genes 0.000 claims description 111
- 108090000623 proteins and genes Proteins 0.000 claims description 111
- 230000008569 process Effects 0.000 claims description 102
- 239000012530 fluid Substances 0.000 claims description 80
- 239000013049 sediment Substances 0.000 claims description 62
- 239000012223 aqueous fraction Substances 0.000 claims description 59
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 58
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 56
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 53
- 150000001413 amino acids Chemical class 0.000 claims description 38
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 31
- 229920001184 polypeptide Polymers 0.000 claims description 24
- 239000002002 slurry Substances 0.000 claims description 18
- 239000007921 spray Substances 0.000 claims description 18
- 238000001035 drying Methods 0.000 claims description 16
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 13
- 230000004323 axial length Effects 0.000 claims description 8
- KWYUFKZDYYNOTN-UHFFFAOYSA-M potassium hydroxide Substances [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 5
- 238000004064 recycling Methods 0.000 claims description 5
- 238000010924 continuous production Methods 0.000 claims description 4
- 230000000750 progressive effect Effects 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 2
- 238000000227 grinding Methods 0.000 claims description 2
- 230000003472 neutralizing effect Effects 0.000 claims description 2
- 210000001519 tissue Anatomy 0.000 description 283
- 235000018102 proteins Nutrition 0.000 description 104
- 239000007787 solid Substances 0.000 description 59
- 239000000243 solution Substances 0.000 description 59
- 210000000988 bone and bone Anatomy 0.000 description 58
- 241000196324 Embryophyta Species 0.000 description 48
- 229940024606 amino acid Drugs 0.000 description 36
- 235000001014 amino acid Nutrition 0.000 description 36
- 102000004190 Enzymes Human genes 0.000 description 35
- 108090000790 Enzymes Proteins 0.000 description 35
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 33
- 239000007788 liquid Substances 0.000 description 32
- 239000000047 product Substances 0.000 description 29
- 239000002994 raw material Substances 0.000 description 29
- 239000000376 reactant Substances 0.000 description 29
- 241000972773 Aulopiformes Species 0.000 description 23
- 235000019515 salmon Nutrition 0.000 description 23
- 239000000203 mixture Substances 0.000 description 20
- 239000002245 particle Substances 0.000 description 18
- 102000008186 Collagen Human genes 0.000 description 17
- 108010035532 Collagen Proteins 0.000 description 17
- 229920001436 collagen Polymers 0.000 description 17
- 239000012071 phase Substances 0.000 description 17
- 239000000843 powder Substances 0.000 description 16
- 238000000926 separation method Methods 0.000 description 16
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- 239000000839 emulsion Substances 0.000 description 10
- 238000004458 analytical method Methods 0.000 description 9
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- 238000010438 heat treatment Methods 0.000 description 9
- 241000251468 Actinopterygii Species 0.000 description 8
- 108091005804 Peptidases Proteins 0.000 description 8
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 8
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 8
- 239000003153 chemical reaction reagent Substances 0.000 description 8
- 235000019688 fish Nutrition 0.000 description 8
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- 239000004365 Protease Substances 0.000 description 7
- 150000007513 acids Chemical class 0.000 description 7
- 230000008901 benefit Effects 0.000 description 7
- 239000007858 starting material Substances 0.000 description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 6
- 239000007789 gas Substances 0.000 description 6
- 150000002632 lipids Chemical class 0.000 description 6
- 239000002699 waste material Substances 0.000 description 6
- 235000019750 Crude protein Nutrition 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 5
- 230000004888 barrier function Effects 0.000 description 5
- 238000006911 enzymatic reaction Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 244000144977 poultry Species 0.000 description 5
- 238000011084 recovery Methods 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- 230000000717 retained effect Effects 0.000 description 5
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 4
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 4
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 4
- 239000001506 calcium phosphate Substances 0.000 description 4
- 229910000389 calcium phosphate Inorganic materials 0.000 description 4
- 235000011010 calcium phosphates Nutrition 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 230000002255 enzymatic effect Effects 0.000 description 4
- 238000001704 evaporation Methods 0.000 description 4
- 210000000003 hoof Anatomy 0.000 description 4
- 239000011159 matrix material Substances 0.000 description 4
- 229910017604 nitric acid Inorganic materials 0.000 description 4
- 235000011007 phosphoric acid Nutrition 0.000 description 4
- 229960002429 proline Drugs 0.000 description 4
- 235000013930 proline Nutrition 0.000 description 4
- 239000011541 reaction mixture Substances 0.000 description 4
- 239000008399 tap water Substances 0.000 description 4
- 235000020679 tap water Nutrition 0.000 description 4
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 4
- 230000002378 acidificating effect Effects 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 238000013459 approach Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000012423 maintenance Methods 0.000 description 3
- 235000013372 meat Nutrition 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 241000238421 Arthropoda Species 0.000 description 2
- 241000698776 Duma Species 0.000 description 2
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 2
- 241000238631 Hexapoda Species 0.000 description 2
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 description 2
- 241000237852 Mollusca Species 0.000 description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 2
- 238000010923 batch production Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000000845 cartilage Anatomy 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 230000005574 cross-species transmission Effects 0.000 description 2
- 210000003298 dental enamel Anatomy 0.000 description 2
- 210000004268 dentin Anatomy 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 235000015872 dietary supplement Nutrition 0.000 description 2
- 238000010494 dissociation reaction Methods 0.000 description 2
- 230000005593 dissociations Effects 0.000 description 2
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 235000019197 fats Nutrition 0.000 description 2
- 239000012065 filter cake Substances 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 229960002591 hydroxyproline Drugs 0.000 description 2
- 230000002779 inactivation Effects 0.000 description 2
- 238000006386 neutralization reaction Methods 0.000 description 2
- 239000011368 organic material Substances 0.000 description 2
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 2
- 230000002250 progressing effect Effects 0.000 description 2
- 238000007873 sieving Methods 0.000 description 2
- 239000007790 solid phase Substances 0.000 description 2
- 239000001117 sulphuric acid Substances 0.000 description 2
- 210000002435 tendon Anatomy 0.000 description 2
- 210000000515 tooth Anatomy 0.000 description 2
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 238000003828 vacuum filtration Methods 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 208000035404 Autolysis Diseases 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 206010057248 Cell death Diseases 0.000 description 1
- 102100033067 Growth factor receptor-bound protein 2 Human genes 0.000 description 1
- 108091009389 Growth factor receptor-bound protein 2 Proteins 0.000 description 1
- 238000007696 Kjeldahl method Methods 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000011260 aqueous acid Substances 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000009838 combustion analysis Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 235000019784 crude fat Nutrition 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000008240 homogeneous mixture Substances 0.000 description 1
- 239000000413 hydrolysate Substances 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000000415 inactivating effect Effects 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 235000019725 meat derivatives Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000007065 protein hydrolysis Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000028043 self proteolysis Effects 0.000 description 1
- 235000015170 shellfish Nutrition 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/001—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from waste materials, e.g. kitchen waste
- A23J1/002—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from waste materials, e.g. kitchen waste from animal waste materials
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/10—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from hair, feathers, horn, skins, leather, bones, or the like
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/04—Animal proteins
- A23J3/06—Gelatine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
- A23J3/342—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of collagen; of gelatin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/28—Moving reactors, e.g. rotary drums
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/10—Rotating vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M43/00—Combinations of bioreactors or fermenters with other apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Processing Of Solid Wastes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Extraction Or Liquid Replacement (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Meat, Egg Or Seafood Products (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2115923.1A GB2612617A (en) | 2021-11-05 | 2021-11-05 | Demineralisation of organic tissue |
| CN202280077923.XA CN118382690A (zh) | 2021-11-05 | 2022-11-04 | 有机组织的去矿化 |
| CA3237470A CA3237470A1 (en) | 2021-11-05 | 2022-11-04 | Demineralisation of organic tissue |
| AU2022381538A AU2022381538A1 (en) | 2021-11-05 | 2022-11-04 | Demineralisation of organic tissue |
| EP22800306.7A EP4426809A1 (en) | 2021-11-05 | 2022-11-04 | Demineralisation of organic tissue |
| PCT/EP2022/080863 WO2023079104A1 (en) | 2021-11-05 | 2022-11-04 | Demineralisation of organic tissue |
| KR1020247017863A KR20240095314A (ko) | 2021-11-05 | 2022-11-04 | 유기 조직의 탈무기질화 |
| JP2024527081A JP2024540401A (ja) | 2021-11-05 | 2022-11-04 | 有機組織の脱灰 |
| PE2024001000A PE20241290A1 (es) | 2021-11-05 | 2022-11-04 | Desmineralizacion de tejido organico |
| ZA2024/03118A ZA202403118B (en) | 2021-11-05 | 2024-04-22 | Demineralisation of organic tissue |
| CL2024001352A CL2024001352A1 (es) | 2021-11-05 | 2024-05-03 | Desmineralización de tejido orgánico |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2115923.1A GB2612617A (en) | 2021-11-05 | 2021-11-05 | Demineralisation of organic tissue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB2612617A true GB2612617A (en) | 2023-05-10 |
Family
ID=84245750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2115923.1A Pending GB2612617A (en) | 2021-11-05 | 2021-11-05 | Demineralisation of organic tissue |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP4426809A1 (https=) |
| JP (1) | JP2024540401A (https=) |
| KR (1) | KR20240095314A (https=) |
| CN (1) | CN118382690A (https=) |
| AU (1) | AU2022381538A1 (https=) |
| CA (1) | CA3237470A1 (https=) |
| CL (1) | CL2024001352A1 (https=) |
| GB (1) | GB2612617A (https=) |
| PE (1) | PE20241290A1 (https=) |
| WO (1) | WO2023079104A1 (https=) |
| ZA (1) | ZA202403118B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT202300021591A1 (it) * | 2023-10-17 | 2025-04-17 | Italia Alimentari S P A | Metodi e sistemi per la simultanea produzione di osseina-idrossiapatite e di collagene e/o gelati-ne e /o relativi peptidi con minori residui da contaminanti antinutrizionali quali anidride sol-forosa, perossido d’idrogeno, metalli pesanti, con bassa carica batterica aerobia, muffe e lie-viti, come materia prima o in forma di prodotto finito, idonei per l’uso umano |
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| EP0050431A1 (en) * | 1980-10-07 | 1982-04-28 | Nordjyske Andelsslagteriers Fabrikker Andelsselskab | Protein production |
| JPH03139291A (ja) * | 1989-10-23 | 1991-06-13 | Daisan Kasei Kk | 酵素を用いる甲殼類の甲殼の処理方法 |
| US5459241A (en) * | 1987-12-30 | 1995-10-17 | Systems Bio Industries | Continuous process for the preparation of gelatin from powdered bone, and gelatin obtained |
| US20070254040A1 (en) * | 2006-05-01 | 2007-11-01 | James Scaffidi | Nutritional supplement and use thereof |
| CN103755834A (zh) * | 2014-01-26 | 2014-04-30 | 扬州日兴生物科技股份有限公司 | 一种从虾蟹副产物制备活性肽粉和甲壳素的方法 |
| US20160231056A1 (en) * | 2015-02-09 | 2016-08-11 | Warsaw Orthopedic, Inc. | Methods for treating tissue materials |
| GB2548386A (en) * | 2016-03-17 | 2017-09-20 | Alkymar As | Mixing and processing apparatus |
| CN111647097A (zh) * | 2020-05-29 | 2020-09-11 | 江苏美鑫食品科技有限公司 | 一种从废弃虾壳中提取甲壳素的方法 |
| WO2021146240A1 (en) * | 2020-01-13 | 2021-07-22 | Cargill, Incorporated | Turkey collagen hydrolysates and methods of making |
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| DK164252C (da) * | 1986-11-11 | 1995-10-30 | Slagteriernes Forskningsinst | Fremgangsmåde ved fremstilling af proteinprodukter ud fra benholdigt, animalsk materiale |
| GB0902018D0 (en) * | 2009-02-09 | 2009-03-11 | Fugeia | Method for making pentoses and pentose-based oligosaccharides from cereals |
| WO2016204596A1 (es) * | 2015-06-16 | 2016-12-22 | Industrias Vepinsa, S.A. de C.V. | Proceso hibrido biotecnologico-quimico para la obtencion de quitina de alta pureza a partir de exoesqueletos de desechos de origen biologico |
-
2021
- 2021-11-05 GB GB2115923.1A patent/GB2612617A/en active Pending
-
2022
- 2022-11-04 CA CA3237470A patent/CA3237470A1/en active Pending
- 2022-11-04 CN CN202280077923.XA patent/CN118382690A/zh active Pending
- 2022-11-04 PE PE2024001000A patent/PE20241290A1/es unknown
- 2022-11-04 KR KR1020247017863A patent/KR20240095314A/ko active Pending
- 2022-11-04 JP JP2024527081A patent/JP2024540401A/ja active Pending
- 2022-11-04 WO PCT/EP2022/080863 patent/WO2023079104A1/en not_active Ceased
- 2022-11-04 EP EP22800306.7A patent/EP4426809A1/en active Pending
- 2022-11-04 AU AU2022381538A patent/AU2022381538A1/en active Pending
-
2024
- 2024-04-22 ZA ZA2024/03118A patent/ZA202403118B/en unknown
- 2024-05-03 CL CL2024001352A patent/CL2024001352A1/es unknown
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0050431A1 (en) * | 1980-10-07 | 1982-04-28 | Nordjyske Andelsslagteriers Fabrikker Andelsselskab | Protein production |
| US5459241A (en) * | 1987-12-30 | 1995-10-17 | Systems Bio Industries | Continuous process for the preparation of gelatin from powdered bone, and gelatin obtained |
| JPH03139291A (ja) * | 1989-10-23 | 1991-06-13 | Daisan Kasei Kk | 酵素を用いる甲殼類の甲殼の処理方法 |
| US20070254040A1 (en) * | 2006-05-01 | 2007-11-01 | James Scaffidi | Nutritional supplement and use thereof |
| CN103755834A (zh) * | 2014-01-26 | 2014-04-30 | 扬州日兴生物科技股份有限公司 | 一种从虾蟹副产物制备活性肽粉和甲壳素的方法 |
| US20160231056A1 (en) * | 2015-02-09 | 2016-08-11 | Warsaw Orthopedic, Inc. | Methods for treating tissue materials |
| GB2548386A (en) * | 2016-03-17 | 2017-09-20 | Alkymar As | Mixing and processing apparatus |
| WO2021146240A1 (en) * | 2020-01-13 | 2021-07-22 | Cargill, Incorporated | Turkey collagen hydrolysates and methods of making |
| CN111647097A (zh) * | 2020-05-29 | 2020-09-11 | 江苏美鑫食品科技有限公司 | 一种从废弃虾壳中提取甲壳素的方法 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT202300021591A1 (it) * | 2023-10-17 | 2025-04-17 | Italia Alimentari S P A | Metodi e sistemi per la simultanea produzione di osseina-idrossiapatite e di collagene e/o gelati-ne e /o relativi peptidi con minori residui da contaminanti antinutrizionali quali anidride sol-forosa, perossido d’idrogeno, metalli pesanti, con bassa carica batterica aerobia, muffe e lie-viti, come materia prima o in forma di prodotto finito, idonei per l’uso umano |
Also Published As
| Publication number | Publication date |
|---|---|
| PE20241290A1 (es) | 2024-06-21 |
| CL2024001352A1 (es) | 2024-10-11 |
| JP2024540401A (ja) | 2024-10-31 |
| CN118382690A (zh) | 2024-07-23 |
| CA3237470A1 (en) | 2023-05-11 |
| WO2023079104A1 (en) | 2023-05-11 |
| AU2022381538A1 (en) | 2024-06-13 |
| EP4426809A1 (en) | 2024-09-11 |
| ZA202403118B (en) | 2025-08-27 |
| KR20240095314A (ko) | 2024-06-25 |
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