GB2594094A - Method for diagnosing stroke caused by large vessel occlusion - Google Patents

Method for diagnosing stroke caused by large vessel occlusion Download PDF

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Publication number
GB2594094A
GB2594094A GB2005632.1A GB202005632A GB2594094A GB 2594094 A GB2594094 A GB 2594094A GB 202005632 A GB202005632 A GB 202005632A GB 2594094 A GB2594094 A GB 2594094A
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GB
United Kingdom
Prior art keywords
stroke
biomarker
lvo
individual
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB2005632.1A
Other languages
English (en)
Other versions
GB202005632D0 (en
Inventor
Gaude Edoardo
Ladreda Mochales Gonzalo
Ladreda Mochales Marcos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pockit Diagnostics Ltd
Original Assignee
Pockit Diagnostics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pockit Diagnostics Ltd filed Critical Pockit Diagnostics Ltd
Priority to GB2005632.1A priority Critical patent/GB2594094A/en
Publication of GB202005632D0 publication Critical patent/GB202005632D0/en
Priority to JP2022563013A priority patent/JP7711092B2/ja
Priority to EP20838261.4A priority patent/EP4136458A1/en
Priority to GB2200967.4A priority patent/GB2600844B/en
Priority to PCT/GB2020/053340 priority patent/WO2021209732A1/en
Priority to KR1020227039385A priority patent/KR20230004594A/ko
Priority to GB2407291.0A priority patent/GB2627388B/en
Publication of GB2594094A publication Critical patent/GB2594094A/en
Priority to US17/934,454 priority patent/US11726100B2/en
Priority to US18/327,243 priority patent/US12584925B2/en
Withdrawn legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/08—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point
    • B05B7/0807—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point to form intersecting jets
    • B05B7/0815—Spray pistols; Apparatus for discharge with separate outlet orifices, e.g. to form parallel jets, i.e. the axis of the jets being parallel, to form intersecting jets, i.e. the axis of the jets converging but not necessarily intersecting at a point to form intersecting jets with at least one gas jet intersecting a jet constituted by a liquid or a mixture containing a liquid for controlling the shape of the latter
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B05B7/02—Spray pistols; Apparatus for discharge
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    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
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    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
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    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
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    • G01N2333/75—Fibrin; Fibrinogen
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Textile Engineering (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB2005632.1A 2020-04-17 2020-04-17 Method for diagnosing stroke caused by large vessel occlusion Withdrawn GB2594094A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GB2005632.1A GB2594094A (en) 2020-04-17 2020-04-17 Method for diagnosing stroke caused by large vessel occlusion
GB2407291.0A GB2627388B (en) 2020-04-17 2020-12-22 Method for diagnosing stroke caused by large vessel occlusion
PCT/GB2020/053340 WO2021209732A1 (en) 2020-04-17 2020-12-22 D-dimer, glial fibrillary acidic protein (gfap), osteoprotegerin (opg) and osteopontin (opn) as biomarkers for stroke caused by large vessel occlusion
EP20838261.4A EP4136458A1 (en) 2020-04-17 2020-12-22 D-dimer, glial fibrillary acidic protein (gfap), osteoprotegerin (opg) and osteopontin (opn) as biomarkers for stroke caused by large vessel occlusion
GB2200967.4A GB2600844B (en) 2020-04-17 2020-12-22 Method for diagnosing stroke caused by large vessel occlusion
JP2022563013A JP7711092B2 (ja) 2020-04-17 2020-12-22 大血管閉塞により引き起こされる卒中についてのバイオマーカーとしてのｄ－ダイマー、グリア線維酸性タンパク質（ｇｆａｐ）、オステオプロテジェリン（ｏｐｇ）及びオステオポンチン（ｏｐｎ）
KR1020227039385A KR20230004594A (ko) 2020-04-17 2020-12-22 대혈관 폐색으로 인한 뇌졸중 진단 방법
US17/934,454 US11726100B2 (en) 2020-04-17 2022-09-22 Method of treating large vessel occlusion stroke
US18/327,243 US12584925B2 (en) 2020-04-17 2023-06-01 Method of treating large vessel occlusion stroke

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2005632.1A GB2594094A (en) 2020-04-17 2020-04-17 Method for diagnosing stroke caused by large vessel occlusion

Publications (2)

Publication Number Publication Date
GB202005632D0 GB202005632D0 (en) 2020-06-03
GB2594094A true GB2594094A (en) 2021-10-20

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ID=70860060

Family Applications (3)

Application Number Title Priority Date Filing Date
GB2005632.1A Withdrawn GB2594094A (en) 2020-04-17 2020-04-17 Method for diagnosing stroke caused by large vessel occlusion
GB2407291.0A Active GB2627388B (en) 2020-04-17 2020-12-22 Method for diagnosing stroke caused by large vessel occlusion
GB2200967.4A Active GB2600844B (en) 2020-04-17 2020-12-22 Method for diagnosing stroke caused by large vessel occlusion

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Application Number Title Priority Date Filing Date
GB2407291.0A Active GB2627388B (en) 2020-04-17 2020-12-22 Method for diagnosing stroke caused by large vessel occlusion
GB2200967.4A Active GB2600844B (en) 2020-04-17 2020-12-22 Method for diagnosing stroke caused by large vessel occlusion

Country Status (6)

Country Link
US (2) US11726100B2 (cg-RX-API-DMAC7.html)
EP (1) EP4136458A1 (cg-RX-API-DMAC7.html)
JP (1) JP7711092B2 (cg-RX-API-DMAC7.html)
KR (1) KR20230004594A (cg-RX-API-DMAC7.html)
GB (3) GB2594094A (cg-RX-API-DMAC7.html)
WO (1) WO2021209732A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220381794A1 (en) * 2019-05-16 2022-12-01 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Method for selecting a patient for a reperfusion therapy
GB2594094A (en) * 2020-04-17 2021-10-20 Pockit Diagnostics Ltd Method for diagnosing stroke caused by large vessel occlusion
US20240192231A1 (en) * 2021-04-15 2024-06-13 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Markers for the diagnosis of large vessel occlusion
KR20250004423A (ko) * 2023-06-29 2025-01-08 프리시젼바이오 주식회사 허혈성 뇌졸증 진단용 분석장치

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042607A1 (en) * 1998-02-24 1999-08-26 The University Of Notre Dame Du Lac Use of succinate as a diagnostic tool
WO2012009567A2 (en) * 2010-07-15 2012-01-19 The Regents Of The University Of California Biomarkers for diagnosis of stroke and its causes
WO2016087611A1 (en) * 2014-12-03 2016-06-09 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Methods for differentiating ischemic stroke from hemorrhagic stroke

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US5707796A (en) 1990-06-11 1998-01-13 Nexstar Pharmaceuticals, Inc. Method for selecting nucleic acids on the basis of structure
US5567588A (en) 1990-06-11 1996-10-22 University Research Corporation Systematic evolution of ligands by exponential enrichment: Solution SELEX
US5496938A (en) 1990-06-11 1996-03-05 Nexstar Pharmaceuticals, Inc. Nucleic acid ligands to HIV-RT and HIV-1 rev
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US5683867A (en) 1990-06-11 1997-11-04 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: blended SELEX
US5637459A (en) 1990-06-11 1997-06-10 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chimeric selex
ES2259800T3 (es) 1990-06-11 2006-10-16 Gilead Sciences, Inc. Procedimientos de uso de ligandos de acido nucleico.
US7392140B2 (en) 2003-09-23 2008-06-24 Prediction Sciences, Llc Cellular fibronectin as a diagnostic marker in stroke and methods of use thereof
CN106011233A (zh) * 2010-08-13 2016-10-12 莫尔豪斯医学院 中风的生物标记
GB201309928D0 (en) 2013-06-04 2013-07-17 Randox Lab Ltd Method
US11774457B2 (en) * 2018-07-09 2023-10-03 Wright State University Identification and analysis of protein biomarkers
US20220381794A1 (en) * 2019-05-16 2022-12-01 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Method for selecting a patient for a reperfusion therapy
GB2594094A (en) 2020-04-17 2021-10-20 Pockit Diagnostics Ltd Method for diagnosing stroke caused by large vessel occlusion

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042607A1 (en) * 1998-02-24 1999-08-26 The University Of Notre Dame Du Lac Use of succinate as a diagnostic tool
WO2012009567A2 (en) * 2010-07-15 2012-01-19 The Regents Of The University Of California Biomarkers for diagnosis of stroke and its causes
WO2016087611A1 (en) * 2014-12-03 2016-06-09 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Methods for differentiating ischemic stroke from hemorrhagic stroke

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Biochimica et Biophysica Acta - Molecular Basis of Disease, vol. 1863, no.9, 2017, Wu et al., "Succinate-induced neuronal mitochondrial fission and hexokinase II malfunction in ischemic stroke: Therapeutical effects of kaempferol", pages 2307-2318. *
Nature, vol 515, 2014, Couchani et al, "Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.", pages 431-435. *

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