GB2551597A - Method for reducing the body odor caused by perspiration by using special protein hydrolysates - Google Patents

Abstract

A cosmetic method for reducing the body odour caused by perspiration in which a cosmetic agent is applied to human skin and remains at the application site for at least an hour. The cosmetic agent comprises at least one protein hydrolysate selected from wheat protein hydrolysates, soy protein hydrolysates, rice protein hydrolysates, pea protein hydrolysates, hydrolysed keratin and protein hydrolysates from the seeds of Adansonia digitata or mixtures thereof and at least one active ingredient selected from deodorant active agents, antiperspirant aluminium salts, antiperspirant aluminium-zirconium salts and mixtures thereof. The protein hydrolysate may comprise 1.0-40% of the cosmetic agent. The deodorant active agent may be selected from silver and/or zinc salts, aromatic alcohols, 1,2-alkandediols with 5-12 carbon atoms, triethyl citrates, active ingredients against exoesterases, cationic phospholipids, odour absorbers, deodorant ion exchangers, antimicrobial agents, prebiotic components, chelating agents, sorbitan caprylate and/or glucono-delta-lactone and mixtures thereof and may comprise 0.0005-20% of the cosmetic agent. The antiperspirant aluminium salt or aluminium-zirconium salt may comprise 0.1-35% of the cosmetic agent. The cosmetic agent may comprise at least one hydrolysed starch.

Description

Method for reducing the body odor caused by perspiration by using special protein hydrolysates [0001] The present patent application relates to a method for reducing the body odor caused by perspiration by using a cosmetic agent containing at least one special protein hydrolysate as well as at least one deodorant active ingredient and/or an antiperspirant active ingredient. These methods have an excellent deodorant power which also persists for a long period of time.

[0002] In addition, the present invention relates to the use of special protein hydrolysates for reducing and/or preventing the body odor caused by perspiration. Both eccrine and apocrine sweat glands occur in the human axillary cavity. Whereas eccrine glands produce an aqueous secretion in response to heat, the apocrine glands produce a viscous secretion in response to stress. This apocrine perspiration is a complex mixture containing steroids, cholesterol and other fats, among other things, as well as approximately 10% proteins. Bacterial decomposition of the ingredients of apocrine perspiration causes formation of an unpleasant body odor in the underarm area from the initially odorless secretion. The decomposition products of apocrine perspiration which contribute significantly toward body odor in particular toward the axillary body odor can be divided into three classes: the first class is formed by short chain C4-C10 fatty acids which may be linear, branched, saturated and unsaturated (for example, isovaleric acid, 3-methyl-2-hexenoic acid, 3-hydroxy-3-methylhexanoic acid); the second class is formed by short-chain linear or branched sulfanyl alcohols, while the third class consists of various steroid hormones and their metabolites (for example, 5-a-androstenol and 5-a-androstenone).

[0003] Body odor may thus be combatted by preventing bacterial degradation of perspiration or by using perfume to mask the body odor. To prevent bacterial degradation of perspiration, antimicrobial substances, which reduce the number of bacteria that decompose perspiration on the skin by killing them or inhibit the growth of these bacteria, are used in the state of the art. In addition, active ingredients, which reduce or prevent the formation of decomposition products by blocking bacterial enzymes, are known. Furthermore, it is known that the volatile decomposition products can be absorbed and body odor can be prevented by physical and/or chemical interactions in this way. However, there is still a demand for methods that will lead to a high effect as well as a long-lasting deodorant effect against body odor.

[0004] The object of the present invention was therefore to reduce and/or prevent body odor in such a way as to have a good and long-lasting effect against body odor. In addition, the occurrence of skin rashes and/or skin irritation, during and/or after carrying out the method according to the invention, should be avoided.

[0005] It has surprisingly been found that the use of a combination of special protein hydrolysates with at least one deodorant active ingredient and/or an antiperspirant active ingredient results in a high and nevertheless unexpectedly long-lasting deodorant effect.

[0006] A first subject matter of the present patent application is therefore a cosmetic method for reducing the body odor caused by perspiration in which a cosmetic agent (M1) is applied to the human skin and remains at the site of application for at least one hour, wherein the antiperspirant cosmetic agent (M1) contains in a cosmetically tolerable vehicle: a) at least one protein hydrolysate selected from the group of wheat protein hydrolysates, soy protein hydrolysates, rice protein hydrolysates, pea protein hydrolysates, hydrolyzed keratin, protein hydrolysates from the seeds of Adansonia digitata as well as mixtures thereof, and b) at least one active ingredient selected from the group of deodorant active ingredients, antiperspirant aluminum salts, antiperspirant aluminum-zirconium salts and mixtures thereof.

[0007] An excellent reduction in body odor, in particular axillary body odor, is achieved without causing skin irritation by using cosmetic agents containing at least one special protein hydrolysate and at least one deodorant active ingredient and/or an antiperspirant active ingredient in the method according to the invention.

[0008] The term "antiperspirant" is understood according to the invention to refer to a reduction and/or diminution in the perspiration from the body's sudoriferous glands.

[0009] The term "protein hydrolysates" denotes according to the invention proteins which are produced by hydrolysis of naturally occurring wheat proteins, naturally occurring soy proteins, naturally occurring rice proteins, naturally occurring pea proteins, naturally occurring keratin and naturally occurring proteins from the seeds of Adansonia digitata, for example, by chemical in particular alkaline or acidic hydrolysis, by enzymatic hydrolysis and/or by a combination of the two types of hydrolysis. All hydrolytically active enzymes such as alkaline proteases, for example, are suitable for enzymatic degradation. Reviews of the production of protein hydrolysates have been published, for example, by G. Schuster and A. Domsch in Seifen Ole Fette Wachse 108 (1982), 177 and Cosm. Toil. 99 (1984), 63 by H. W. Steisslinger in Parf. Kosm. 72 (1991), 556 and F. Aurich et al. in Tens. Surf. Det. 29 (1992), 389. Mixtures of individual amino acids obtained only by mixing the pure substances of the amino acids as well as total hydrolysates consisting only of individual amino acids do not fall under the heading of "hydrolyzed proteins" and/or "protein hydrolysates" within the scope of the present invention.

[0010] In addition, within the scope of the present invention, the terms "aluminum salts and aluminum zirconium salts" are understood in particular to include chlorides, bromides and iodides of aluminum and/or zirconium as well as compounds of the formulas AI(OH)yX and Zr(OH)zX, where X in the aforementioned formulas stands fora halide ion.

[0011] In addition, the term "deodorant active ingredient" according to the invention is understood to refer to an active ingredient which reduces and/or prevents the development of body odor due to bacterial decomposition of perspiration, in particular axillary perspiration. However, this does not include the protein hydrolysates listed under feature a), or ethanol, which is optionally used as a component of the cosmetic vehicle.

[0012] Furthermore, the term "fatty acid" as used within the scope of the present invention is understood to refer to aliphatic carboxylic acids which have branched or unbranched carbon radicals with 4 to 40 carbon atoms. The fatty acids used within the scope of the present invention may be naturally occurring as well as synthetic fatty acids. In addition, the fatty acids may be mono-or polyunsaturated.

[0013] Finally, the term "fatty alcohol" used within the scope of the present invention is understood to refer to aliphatic, monovalent primary alcohols which have branched or unbranched hydrocarbon radicals with 4 to 40 carbon atoms. The fatty alcohols used within the scope of the invention may also be mono- or polyunsaturated.

[0014] The specification of percentage by weight, unless otherwise indicated, in the present case refers to the total weight of the cosmetic agent (M1) used according to the invention, wherein the total of all ingredients of the agents (M1) used according to the invention yields 100% by weight. In addition, the percentage amount by weight, unless otherwise indicated, refers to the amount of the respective component in the propellant-free cosmetic agent (M1) used so that the amount of propellant optionally present is not taken into account in the calculation of the total weight of the cosmetic agents (M1) used.

[0015] The cosmetic agent contains the ingredients a) and b) in a cosmetically tolerable vehicle, which preferably contains at least one component selected from water, a (^-04 alcohol, a cosmetic oil that is liquid under normal conditions as well as mixtures thereof. The cosmetic oils that are liquid under normal conditions are not miscible with water and are neither perfumes nor essential oils. "Normal conditions" in the sense of the present patent application refer to a temperature of 20°C and a pressure of 1.013 hPa.

[0016] Suitable cosmetic vehicles include, for example, aqueous or aqueous alcohol vehicles. These are understood to be vehicles containing more than 5.0% by weight water or more than 5% by weight water and at least one (^-04 alcohol, each based on the total weight of the propellant-free cosmetic agent. Aqueous vehicle preferably contains free water in a total amount of 10 to 96% by weight, preferably 15 to 80% by weight, more preferably 30 to 70% by weight, in particular 40 to 60% by weight, based on the total weight of the propellant-free cosmetic agent. Ethanol is preferably contained in the aqueous alcoholic vehicle in a total amount of 0.1 to 50% by weight, preferably 0.5 to 30% by weight, more preferably 1.0 to 20% by weight, in particular 1.0 to 9.0% by weight, based on the total weight of the propellant-free cosmetic agent.

[0017] The aqueous and aqueous alcoholic vehicles listed above may also contain at least one (C2-C6) alkyl alcohol with two or three hydroxyl groups, in particular 1,2-propylene glycol, 1,3-propylene glycol, glycerol and 1,3-butylene glycol.

[0018] However, it is also possible to provide that an anhydrous cosmetic vehicle is to be used. Anhydrous vehicles are understood according to the invention to be vehicles containing free water in an amount of less than 5.0% by weight, preferably less than 4.0% by weight, more preferably less than 3.0% by weight, in particular 0% by weight, based on the total weight of the propellant-free cosmetic agent. Free water in the sense of the present invention is understood to be water which is different from water of crystallization, hydration water or molecularly bonded water of the ingredients used. However, in calculating the total amount of free water, water of crystallization, hydration water or similarly molecular bound water of the ingredients used are not taken into account.

[0019] In this context, alcoholic media are used in particular as the cosmetically tolerable vehicles. The lower alcohols with 1 to 4 carbon atoms that are generally used as the alcohols for cosmetic purposes in particular, for example, ethanol and isopropanol may be present. Alcoholic vehicles preferably contain ethanol in a total amount of 20 to 95% by weight, preferably 25 to 65% by weight, in particular 25 to 60% by weight, based on the total weight of the propellant-free cosmetic agent. In addition, it is especially preferred in this context to use liquid cosmetic oils as the cosmetic vehicles. These cosmetic oils may be selected from the group of (i) volatile non-silicone oils, in particular liquid paraffin oils and isoparaffin oils such as isodecane, isoundecane, isododecane, isotridecane, isotetradecane, isopentadecane, isohexadecane and isoeicosane; (ii) non-volatile non-silicone oils, in particular the esters of linear or branched saturated or unsaturated C2.3o fatty alcohols with linear or branched saturated or unsaturated C2_30 fatty acids which may be hydroxylated, the C3-C22 fatty alcohol esters of monovalent or polyvalent C2-C7 hydroxycarboxylic acids, the triethyl citrates, the dicarboxylic acid esters of linear or branched C2-C-iq alkanols, the addition products of ethylene oxide and/or propylene oxide onto mono- or polyvalent C3.22 alkanols which may optionally be esterified, the symmetrical, asymmetrical or cyclic esters of carboxylic acid with fatty alcohols, the esters of dimers of unsaturated C12_22 fatty acids with monovalent linear, branches and cyclic C2_i3 alkanols or C2_6 alkanols, the benzoic acid esters of linear or branched C8. 22 alkanols, such as benzoic acid C12_15 alkyl esters and benzoic acid isostearyl esters and benzoic acid octyl dodecyl esters, the synthetic hydrocarbons, such as polyisobutene and polydecenes, the alicyclic hydrocarbons as well as (iii) mixtures thereof [0020] The term "volatile cosmetic oil" according to the invention denotes cosmetic oils which have a vapor pressure from 2.66 Pa to 40,000 Pa (0.02 to 300 mmHg), preferably from 10 to 12.000 Pa (0.1 to 90 mmHg), more preferably from 13 to 3000 Pa (0.1 to 23 mmHg) in particular from 15 to 500 Pa (0.1 to 4 mmHg) at 20°C and an ambient pressure of 1.013 hPa. In addition, the term "nonvolatile cosmetic oils" in the sense of the present invention is understood to include cosmetic oils which have a vapor pressure of less than 2.66 Pa (0.02 mmHg) at 20°C and an ambient pressure of 1.013 hPa.

[0021] Also preferred according to the invention is the use of mixtures of the cosmetic oils listed above, in particular volatile and nonvolatile cosmetic oils, because parameters such as skin feel, visibility of residue and stability of the cosmetic agent according to the invention can be adjusted in this way, and the agent can thus be adapted better to the needs of the consumers.

[0022] It is preferred within the scope of the present invention if the cosmetic oil, which is liquid at 20°C and 1.013 hPa, is used in a total amount of 1.0 to 98% by weight, preferably 2.0 to 95% by weight, more preferably 5.0 to 70% by weight, even more preferably from 10 to 60% by weight, in particular 15 to 50% by weight, based on the total weight of the propellant-free cosmetic agent.

[0023] The cosmetic agent (M1) used according to the invention contains as the first essential ingredient a) at least one protein hydrolysate selected from the group of wheat protein hydrolysates, soy protein hydrolysates, rice protein hydrolysates, pea protein hydrolysates, hydrolyzed keratin, protein hydrolysates from the seeds of Adansonia digitata as well as mixtures thereof.

[0024] It has proven advantageous within the scope of the present invention if the protein hydrolysates used in this cosmetic agents (M1) used according to the invention contain certain amounts of lysine, histidine and arginine. Preferred embodiments of the present invention are therefore characterized in that the cosmetic agent (M1) contains at least one wheat protein hydrolysate - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 1.0 to 1.4 mol%, histidine in an amount of 2.0 to 2.4 mol% and arginine in an amount of 1.8 to 2.2 mol%.

[0025] In addition, it has proven advantageous if the cosmetic agent (M1) contains at least one soy protein hydrolysate - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 5.8 to 6.2 mol%, histidine in an amount of 2.0 to 2.4 mol% and arginine in an amount of 5.4 to 6.0 mol%.

[0026] Furthermore, it is preferred within the scope of the present invention if the cosmetic agent (M1) contains the at least one protein hydrolysate from seeds of Adansonia digitata - based on the total weight of amino acids of the hydrolysate - lysine in a total amount of 4.8 to 5.2% by weight, histidine in a total amount of 2.0 to 2.4% by weight and arginine in a total amount of 7.8 to 8.2% by weight.

[0027] The amounts of amino acids listed above may be carried out by chromatographic determination using sulfonated polystyrene resins, for example (S. Moore et al.: "Chromatography of amino acids on sulfonated polystyrene resin," J. of Biological Chem., 1961, 192, pages 663 to 681). The use of protein hydrolysates containing the amounts of lysine, histidine and arginine listed above has proven to be particularly advantageous with respect to a reduction in body odor due to the methods according to the invention.

[0028] The at least one protein hydrolysate preferably has a certain average molecular weight Mw. The average molecular weight Mw can be determined, for example, by gel permeation chromatography (GPC) (P. Andrews: "Estimation of the Molecular Weights of Proteins by Sephadex Gel Filtration," Biochem. J., 1964, 91, pages 222 to 233). Preferred embodiments of the method according to the invention are therefore characterized in that the cosmetic agent (M1) contains at least one protein hydrolysate with an average molecular weight Mw of 150 to 100,000 Da, preferably of 180 to 50,000 Da, more preferably of 200 to 10,000 Da, even more preferably of 250 to 8000 Da, in particular of 300 to 5000 Da. The use of cosmetic agents (M1) in the methods according to the invention having the average molecular weights Mw listed above results in a particularly effective reduction in the body odor caused by perspiration.

[0029] It may also be advantageous within the scope of the present invention if the cosmetic agents (M1) used according to the invention contain protein hydrolysates with certain isoelectric points (hereinafter referred to as IP). The isoelectric points given below are based on the isoelectric points of the proteins in the protein hydrolysate. The protein hydrolysate therefore has peptides whose isoelectric points are within the ranges given below. It is therefore preferable within the scope of the present invention if the cosmetic agent (M1) contains at least one protein hydrolysate with an isoelectric point of pH 3.0 to pH 10.0, preferably of pH 3.0 to pH 9.5, in particular of pH 3.0 to pH 8.0. The isoelectric point may be determined, for example, by isoelectric focusing (IEF). The proteins in this process are separated as a function of their isoelectric point in a gel matrix, for example, a polyacrylamide or agarose gel using an electric field. The isoelectric point(s) of the respective peptide(s) in the peptide mixture can be determined by using marker proteins with defined isoelectric points.

[0030] According to a preferred embodiment of the present invention, the cosmetic agent contains at least one chemically modified protein hydrolysate, in particular a hydrophobically and/or cationically and/or ionically modified protein hydrolysate selected from the group of wheat protein hydrolysates, soy protein hydrolysates, rice protein hydrolysates, pea protein hydrolysates, hydrolyzed keratin, protein hydrolysates from the seeds of Adansonia digitata as well as mixtures thereof.

[0031] In addition, the term "chemically modified protein hydrolysate" is to be understood within the scope of the present invention as referring to protein hydrolysates obtained by chemical reaction of the reactive groups of the proteins, in particular the hydroxyl, amino, imidazole, guanidino and/or thiol groups of the side chains of the amino acids of the protein hydrolysates with hydrophobic and/or cationic and/or anionic compounds.

[0032] Within the scope of this embodiment, it is especially preferred if the at least one protein is selected from the group of chemically modified, in particular hydrophobically modified protein hydrolysates. In this context the hydrophobically modified protein hydrolysate has at least one C4_30 carbon chain, wherein the C4.30 hydrocarbon chains may be linear, cyclic, branched, unbranched, saturated, unsaturated and aromatic, and wherein the C4_30 hydrocarbon chains are bound by ether and/or ester and/or amine and/or amide bonds to the protein hydrolysate.

[0033] In addition, it is preferred within the scope of this embodiment if the at least one protein hydrolysate is cationically modified. The cationically modified protein hydrolysate preferably contains at least one radical of the formula R1-N+(CH3)2-CH2-CH(OH)-CH2-X-R in which R1 stands for an alkyl group with 1 to 30 carbon atoms, an alkenyl group with 1 to 30 carbon atoms, a hydroxyalkyl group with 1 to 30 carbon atoms, in particular a methyl group, a C10-18 alkyl or a C10-ie alkenyl group, X stands for Ο, N or S and R stands for the protein radical. Cationization of the protein hydrolysates with the radicals described above can be achieved by reacting the protein hydrolysates, in particular the reactive groups of the amino acids of the protein hydrolysates with the corresponding halides of the above formula, wherein the radicals described above may be bound to the protein hydrolysates by ether and/or ester and/or amide and/or amine bonds. Within the scope of the present invention, the term "protein radical" is to be understood to be the backbone of the corresponding protein hydrolysate formed by the linkage of amino acids, with the at least one cationic group being bound to this backbone via the aforementioned bonds.

[0034] The protein hydrolysate(s) is (are) preferably used in certain quantity ranges in the cosmetic agents (M1) used according to the invention. Preferred embodiments of the method according to the invention are therefore characterized in that the cosmetic agent (M1) contains -based on its total weight - the at least one protein hydrolysate, in particular wheat protein hydrolysates and/or soy protein hydrolysates and/or rice protein hydrolysates and/or pea protein hydrolysates and/or hydrolyzed keratin and/or protein hydrolysates from the seeds of Adansonia digitata in a total amount of 1.0 to 40% by weight, preferably 2.0 to 35% by weight, more preferably 2.0 to 30% by weight, in particular 2.0 to 20% by weight. If mixtures of the protein hydrolysates listed above are used, then the total amounts indicated above are based on the mixture of these protein hydrolysates. The use of the at least one protein hydrolysate in the aforementioned quantity ranges in combination with the at least one deodorant active ingredient and/or antiperspirant active ingredient, leads to a high inhibiting effect of odor causing microorganisms. In addition, the deodorizing effects achieved with these quantities persist for a long period of time. Furthermore, these quantities do not result in a negative interaction with other ingredients of the cosmetic agents (M1) used according to the invention, so that these agents have a high stability.

[0035] As the second essential ingredient b) the cosmetic agent (M1) used according to the invention contains at least one active ingredient selected from the group of deodorant active ingredients, antiperspirant aluminum salts, antiperspirant aluminum zirconium salts as well as mixtures thereof.

[0036] Cosmetic agents (M1) preferred for use here contain at least one certain deodorant active ingredient. It is therefore advantageous within the scope of the present invention if the cosmetic agent (M1) contains at least one deodorant active ingredient selected from the group of (i) silver and/or zinc salts, in particular silver lactate, zinc phenol sulfonate and zinc hydroxide carbonate; (ii) aromatic alcohols in particular 2-benzylheptan-1-ol and tropolone as well as mixtures of 2-benzylheptan-1-ol and phenoxyethanol; (iii) 1,2-alkanediols with 5 to 12 carbon atoms, in particular 3-(2-ethylhexyloxy)-1,2-propanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol as well as mixtures of 1,2-hexanediol and 1,2-octanediol; (iv) triethyl citrates; (v) active ingredients against exoesterases, in particular against aryl sulfatase, lipase, beta-glucuronidase and cystathione-β-lyase; (vi) cationic phospholipids, in particular cocamidopropyl PG-dimonium chloride phosphate; (vii) odor absorbers, in particular silicates such as montmorillonite, kaolinite, ilite, beidellite, nontronite, saponite, hectorite, bentonite, smectite and talc, zeolites, zinc ricinoleate, cyclodextrins, magnesium oxide; (viii) deodorant ion exchangers; (ix) antimicrobial agents, in particular cetyl pyridinium chloride, benzalkonium chloride, benzethonium chloride, tartaric acid, carnosic acid, polyglyceryl 2-caprate; (x) prebiotic components; (xi) chelating agents, in particular capryl hydroxamic acid; (xii) sorbitan caprylate and/or glucono-delta-lactone as well as (xi) mixtures thereof.

[0037] Preferred silver salts and/or silver complexes preferably include silver lactate, silver nitrate, silver acetate, silver sulfate and silver citrate as well as combinations thereof with layered silicates and/or talc. Zinc salts that are used preferably include zinc phenol sulfonate, zinc gluconate and zinc hydroxide carbonate.

[0038] It is preferable to use as the alkanediol with 5 to 12 carbon atoms, 2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol as well as mixtures thereof. A mixture of 1,2-hexanediol and 1,2-octanediol in a weight ratio of 5:1 to 1:5 is especially preferred here. In addition, it may be preferable to use a combination of at least one alkanediol with tropolone.

[0039] Silicates are used as odor absorbers, which at the same time can also advantageously support the rheological properties of the cosmetic agents according to the invention. Silicates that are particularly advantageous according to the invention include in particular layered silicates and, of these, in particular montmorillonite, kaolinite, ilite, beidellite, nontronite, saponite, hectorite, bentonite, smectite and talc. Additional advantageous odor absorbers include, for example, zeolites, zinc ricinoleate, cyclodextrins, certain metal oxides such as aluminum oxide and magnesium oxide as well as chlorophyll.

[0040] In addition, the deodorant active ingredient may be selected from the group of terpene alcohols such as farnesol, chlorophyllin copper complexes, α-monoalkyl glycerin ethers with a branched or linear saturated or unsaturated, optionally hydroxylated C6-C22 alkyl radical, especially preferably a-(2-ethylhexyl)glycerol ether, available commercially as Sensiva® SC 50 (from Schiilke & Mayr), carboxylic acid esters, in particular carboxylic acid monoesters of mono-, di- and triglycerol (in particular glycerol monolaurate, diglycerol monocaprinate, diglycerol monolaurate, triglycerol monolaurate and triglycerol monomyristate) as well as plant extracts (for example, green tea and components of lime blossom oil).

[0041] Additional preferred deodorant active ingredients are selected from so-called prebiotic components, which are understood according to the invention to include those components which inhibit only or at least predominately the odor-forming microbes of the microflora of skin but not the desired microbes, i.e., those that do not form odor. These include explicitly pine tree extracts in particular those of the group of Pinaceae and plant extracts from the group of Sapindaceae, Araliaceae, Lamiaceae and Saxifragaceae, in particular extracts of Picea spp., Paullinia sp., Panax sp. Lamium album or Ribes nigrum as well as mixtures of these substances.

[0042] Additional preferred deodorant active ingredients are selected from the antimicrobial perfume oils and the deodorant-safe perfume oils obtainable from the company Symrise, formerly Haarmann and Reimer.

[0043] The enzyme inhibitors include substances that inhibit the enzymes responsible for decomposition of perspiration, in particular aryl sulfatase, β-glucuronidase, aminoacylase, the ester-cleaving lipases and the lipoxygenase, for example, trialkylcitric acid esters, in particular triethyl citrate or zinc glycinate.

[0044] The deodorant active ingredients may be used individually or in mixtures. Especially preferred are a-(2-ethylhexyl)glycerol ethers, diglycerol monocaprinate, 2-methyl-4-phenylbutan--2-ol, mixtures of phenoxyethanol and a-(2-ethylhexyl) glycerol ether as well as mixtures of aryl alcohols in particular phenoxyethanol with a-(2-ethylhexyl) glycerol ethers and diglycerol monocaprinate.

[0045] The at least one deodorant active ingredient is advantageously used in certain quantity ranges in the cosmetic agents (M1) used according to the invention. Preferred cosmetic agents of the present invention are therefore characterized in that they contain - based on the total weight of the propellant-free cosmetic agents - 0.0005 to 20% by weight, preferably 0.1 to 15% by weight, more preferably 0.1 to 10% by weight, in particular 0.1 to 2.0% by weight of at least one deodorant active ingredient. If a mixture of deodorant active ingredients is used, then the quantity information cited above is based on the mixture of these active ingredients. Use of the quantities indicated above ensures an adequate deodorant power. In addition, these quantities do not have a negative effect on the deodorant effect of the at least one protein hydrolysate.

[0046] In addition to or in combination with the at least one deodorant active ingredient, the cosmetic agents (M1) used according to the invention may additionally contain at least one antiperspirant aluminum salt. It is therefore preferred within the scope of the present invention if the cosmetic agent (M1) contains at least one antiperspirant aluminum salt selected from the group of (i) water-soluble astringent inorganic salts of aluminum, in particular aluminum chlorohydrate, aluminum sesquichlorohydrate, aluminum dichlorohydrate, aluminum hydroxide, potassium aluminum sulfate, aluminum bromohydrate, aluminum chloride, aluminum sulfate; (ii) water-soluble astringent organic salts of aluminum, in particular aluminum chlorohydrex propylene glycol, aluminum chlorohydrex polyethylene glycol, aluminum propylene glycol complex, aluminum sesquichlorohydrex propylene glycol, aluminum sesquichlorohydrex polyethylene glycol, aluminum propylene glycol dichlorohydrex, aluminum polyethylene glycol dichlorohydrex, aluminum undecylenoyl collagen amino acid, sodium aluminum lactate, sodium aluminum chlorohydroxylactate, aluminum lipoamino acids, aluminum lactate, aluminum chlorohydroxy-allantoinate, sodium aluminum chlorohydroxylactate; as well as (iii) mixtures thereof.

[0047] In addition, the cosmetic agents (M1) used according to the invention may contain in addition to or in combination with the aforementioned deodorant active ingredients antiperspirant aluminum salts, at least one antiperspirant aluminum zirconium salt.

[0048] Preferred embodiments are therefore characterized in that the cosmetic agent (M1) contains at least one antiperspirant aluminum zirconium salt selected from the group of (i) water-soluble astringent inorganic aluminum zirconium salts, in particular aluminum zirconium trichlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium pentachlorohydrate, aluminum zirconium octachlorohydrate; (ii) water-soluble astringent organic aluminum zirconium salts, in particular aluminum zirconium propylene glycol complexes, aluminum zirconium trichlorohydrex glycine, aluminum zirconium tetrachlorohydrex glycine, aluminum zirconium pentachlorohydrex glycine, aluminum zirconium octachlorohydrex glycine; as well as (iii) mixtures thereof.

[0049] The terms "antiperspirant aluminum salts" and "antiperspirant aluminum zirconium salts" are not understood to include any aluminosilicates or zeolites according to the invention. In addition, water-soluble aluminum salts and/or water-soluble aluminum zirconium salts are understood according to the invention to include salts having a solubility of at least 3% by weight at 20°C, i.e., at least 3 g of the antiperspirant aluminum salt and/or aluminum zirconium salt will dissolve in 97 g water at 20°C.

[0050] Particularly preferred inorganic aluminum salts are selected from aluminum chlorohydrate, in particular aluminum chlorohydrate with the general formula [Al2(OH)5CI-1-6H20]n, preferably [Al2(0H)5CI-2-3H20]n, which may be present in unactivated (polymerized) form or in an activated (depolymerized) form as well as aluminum chlorohydrate with the general formula [AI2(0H)4Cl2-1-6H20]n, preferably [AI2(0H)4Cl2-2-3H20]n, which may be present in unactivated (polymerized) form or in an activated (depolymerized) form.

[0051] Especially preferred antiperspirant aluminum salts according to the invention are selected from so-called "activated" aluminum salts which are also known as antiperspirant active ingredients "with enhanced activity." Such active ingredients are known in the state of the art and are also available commercially. Activated aluminum salts are usually created by heat treatment of a dilute solution of the corresponding salt (e.g., a solution with 10% by weight salt) to increase its HPLC peak-4-to-peak-3 area ratio. The activated salt may then be dried to form a powder, in particular being spray dried. In addition to spray drying, roller drying, for example, is also suitable. Activated aluminum salts typically have an HPLC peak-4-to-peak-3 area ratio of at least 0.4, preferably at least 0.7, in particular at least 0.9, wherein at least 70% of the aluminum can be assigned to these HPLC peaks.

[0052] In this context, "activated" aluminum-zirconium salts, which have a high HPLC peak 5 aluminum content, in particular a peak 5 area of at least 33%, preferably at least 45%, based on the total area under the peaks 2 to 5, measured with HPLC of a 10% by weight aqueous solution of the active ingredient under condition at which the aluminum species in at least four successive peaks are dissolved (referred to as peaks 2 to 5). In addition, the activated aluminum zirconium salt mentioned above can additional be stabilized with a water-soluble strontium salt and/or with a water-soluble calcium salt.

[0053] It is also possible according to the invention to use antiperspirant aluminum salts as nonaqueous solutions or solubilizates of an activated antiperspirant aluminum or aluminum-zirconium salt. Such aluminum and/or aluminum-zirconium salts are stabilized against the loss of activation of the salt by adding an active amount of a polyvalent alcohol having 3 to 6 carbon atoms and 3 to 6 hydroxy groups, preferably propylene glycol, sorbitol and pentaerythritol.

[0054] Especially preferred are also complexes of activated antiperspirant aluminum and/or aluminum-zirconium salts with a polyvalent alcohol containing 20 to 50% by weight, preferably 20 to 42% by weight activated antiperspirant aluminum and/or aluminum-zirconium salt and 2 to 16% by weight molecularly bound water, wherein the remainder to a total of 100% by weight comprises at least one polyvalent alcohol with 3 to 6 carbon atoms and 3 to 6 hydroxyl groups. Propylene glycol, propylene glycol/sorbitol mixtures and propylene glycol/pentaerythritol mixtures are preferred examples of such alcohols.

[0055] Within the scope of the present invention it is also possible to use basic calcium aluminum salts as antiperspirant aluminum salts. These salts can be obtained by reacting calcium carbonate with aluminum chlorohydroxide or aluminum chloride and aluminum powder or by adding calcium chloride dihydrate to aluminum chlorohydroxide. However, it is also possible to use aluminum-zirconium complexes, which are buffered with salts of amino acids, in particular with alkali and alkaline earth glycinates.

[0056] Aluminum and/or aluminum zirconium salts may also be used as the preferred antiperspirant activated aluminum and aluminum zirconium salts according to the invention, these salts preferably being stabilized by amino acids, in particular glycine, hydroxyalkanoic acids, in particular glycolic acid and lactic acid or betaines.

[0057] Additional preferred activated aluminum salts include those of the general formula AI2(OH)6_aXa, where X stands for Cl, Br, I or N03 and "a" stands for a number from 0.3 to 5, preferably from 0.8 to 2.5, in particular from 1 to 2, so that the molar ratio of AI:X is 0.9:1 to 2.1:1. Aluminum chlorohydrate (i.e., X in the formula given above stands for Cl) and specifically 5/6-basic aluminum chlorohydrate, where "a" = 1, are especially preferred, so that the molar ratio of aluminum to chlorine is 1.9:1 to 2.1:1.

[0058] Preferred activated aluminum zirconium salts are those of the general formula ZrO(OH)2-pbYb wherein Y stands for Cl, Br, I, N03 orS04, b stands for a rational number from 0.8 to 2 and p stands for the valence of Y, so that the AI:Zr molar ratio is from 2 to 10 and the metal:(X +Y) ratio is from 0.73 to 2.1, preferably from 0.9 to 1.5. An especially preferred salt is aluminum zirconium chlorohydrate (i.e., X and Y stand for Cl), which has an AI:Zr ratio of 2 to 10 and a molar metal:CI ratio of 0.9 to 2.1.

[0059] Especially preferred antiperspirant aluminum salts according to the invention have a molar metal-to-chloride ratio of 1.9 to 2.1. The metal-to-chloride ratio of aluminum sesquichlorohydrates, which are also especially preferred within the scope of the invention, is 1.5:1 to 1.8:1. Preferred aluminum zirconium tetrachlorohydrates have a molar ratio of AI:Zr of 2 to 6 and a metal:chloride of 0.9 to 1.3, wherein salts with a molar metal-to-chloride ratio of 0.9 to 1.1, preferably of 0.9 to 1.0, are preferred in particular.

[0060] The at least one antiperspirant aluminum and/or aluminum zirconium salt is advantageously used in certain quantity ranges in the cosmetic agents (M1) according to the invention. Preferred methods of the present invention are therefore characterized in that the cosmetic agent (M1) contains the at least one antiperspirant aluminum salt and/or aluminum zirconium salt in a total amount of 0.1 to 35% by weight, preferably of 0.5 to 25% by weight, more preferably of 1.0 to 15% by weight, even more preferably of 1.5 to 10% by weight, in particular of 2.0 to 8.0% by weight - based on the total weight of the cosmetic agent (M1). If a mixture of different antiperspirant aluminum or aluminum zirconium salts and/or a mixture of different antiperspirant aluminum and aluminum zirconium salts is used, then the quantity amounts listed above are based on the mixture of these salts. The use of the amounts listed above ensures an adequate deodorant and antiperspirant power. In addition, these amounts do not have any negative influence on the deodorizing effect of the at least one protein hydrolysate.

[0061] The deodorant effect of the method according to the invention can be further enhanced by adding at least one hydrolyzed starch. Hydrolyzed starch is understood according to the invention to be starch, which has been split into starch fragments, i.e., degraded, by using enzymes or strong acids. Preferred methods according to the invention are therefore characterized in that the cosmetic agent (M1) additionally contains at least one hydrolyzed starch. Due to the use of the hydrolyzed starch in the cosmetic agents (M1) used according to the invention, the deodorant power of the method according to the invention is further enhanced. Furthermore, a prolonged deodorizing effect is achieved.

[0062] Within the scope of the present invention, it may be provided that the cosmetic agents (M1) used according to the invention contain additional active ingredients and other ingredients selected from the group of (i) waxes; (ii) emulsifiers and/or surfactants; (iii) hydrogel-forming agents; (iv) skin cooling active ingredients; (v) propellants; (vi) thickeners and (vii) mixtures thereof.

[0063] The cosmetic agents (M1) used according to the invention may additionally contain at least one wax. The term "waxes" is understood within the scope of the present invention to include substances which are kneadable or solid to friable and hard at 20°C, have a coarse to finely crystalline structure and are transparent to opaque in color but are not vitreous. In addition, these substances melt at temperatures above 25°C without decomposing, are readily liquid (low viscosity) at temperatures above the melting point, have a consistency and solubility that depend greatly on temperature and can be polished with a slight pressure. It is therefore advantageous according to the invention if the cosmetic agent (M1) additionally contains at least one wax selected from the group of (i) coconut fatty acid glycerol mono-, di- and triesters; (ii) Butyrospermum parkii (shea butter); (iii) esters of saturated monovalent C8_18 alcohols with saturated C12_16 monocarboxylic acids; (iv) linear primary C12-C24 alkanols; (v) esters of a saturated monovalent C18-C60 alkanol and a saturated C8-C36 monocarboxylic acid, in particular cetyl behenate, stearyl behenate and C20-C40 alkyl stearate; (vi) glycerol triesters of saturated linear C12-C30 carboxylic acids, which may be hydroxylated, in particular hydrogenated palm oil, hydrogenated coconut oil, hydrogenated castor oil, glyceryl tribehenate and glyceryl tri-12-hydroxystearate; (vii) natural vegetable waxes, in particular candellila wax, carnauba wax, Japan wax, sugar cane wax, ouricoury wax, cork wax, sunflower wax, fruit waxes; (viii) animal waxes, in particular beeswax, shellac wax and spermaceti; (ix) synthetic waxes, in particular montan ester waxes, hydrogenated jojoba waxes and sasol waxes, polyalkylene waxes and polyethylene glycol waxes, C20-C40 dialkyl esters of dimeric acids, C30-50 alkyl beeswax and alkyl and alkylaryl esters of dimer fatty acids, paraffin waxes; as well as (x) mixtures thereof. The cosmetic agent (M1) contains the at least one additional wax, preferably in a total amount from 0.01 to 40% by weight, more preferably from 3 to 30% by weight, more preferably from 5 to 18% by weight, in particular from 6 to 15% by weight, based on the total weight of the cosmetic agent (M1).

[0064] Suitable emulsifiers and surfactants that are preferred according to the invention are selected from anionic, cationic, nonionic, amphoteric, in particular ampholytic and zwitterionic emulsifiers and surfactants. Surfactants are amphiphilic (bifunctional) compounds consisting of at least one hydrophobic molecule product and at least one hydrophilic molecule part. The hydrophobic moiety is preferably a hydrocarbon chain with 8 to 28 carbon atoms, which may be saturated or unsaturated, linear or branched. This C8-C28 alkyl chain is especially preferably linear.

[0065] Anionic surfactants are understood to be surfactants with exclusively anionic charges. They contain, for example, carboxyl groups, sulfonic acid groups or sulfate groups. Especially preferred anionic surfactants are alkyl sulfates, alkyl ether sulfates, acyl glutamates and C8.24 carboxylic acids as well as their salts, the so-called soaps.

[0066] Cationic surfactants are understood to be surfactants with exclusively cationic charges. They contain, for example, quaternary ammonium groups. Preferred cationic surfactants are those of the type of quaternary ammonium compounds, ester quats and amidoamines. Preferred quaternary ammonium compounds include aluminum halides and the imidazolium compounds known by the INCI designations quaternium-27 and quaternium-83. Additional cationic surfactants that can be used according to the invention include the quaternized protein hydrolysates. Preferred ester quats are quaternized ester salts of fatty acids with triethanolamine, quaternized ester salts of fatty acids with diethanol alkylamines and quaternized ester salts of fatty acids with 1,2-dihydroxypropyldialkylamines.

[0067] The amphoteric surfactants are subdivided into ampholytic surfactants and zwitterionic surfactants. Ampholytic surfactants are understood to be surface-active compounds which have both acidic groups (for example, -COOH or-S03H groups) as well as basic hydrophilic groups (for example, amino groups and behave as acids or bases, depending on the conditions. Those skilled in the art understand zwitterionic surfactants to be surfactants having both a negative charge and a positive charge in the same molecule. Examples of preferred zwitterionic surfactants include the betaines, the N-alkyl-N,N-dimethylammonium glycinates, the N-acyl-aminopropyl-N,N-dimethyl-ammonium glycinates and the 2-alkyl-3-carboxymethyl-3-hydroxyethylimidazolines, each having 8 to 24 carbon atoms in the alkyl group. Examples of preferred ampholytic surfactants include N-alkylglycines, N-alkylaminopropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkyl-aminopropionic acids and alkylaminoacetic acids each having 8 to 24 carbon atoms in the alkyl group.

[0068] The cosmetic agents (M1) used according to the invention and formulated as an emulsion, in particular as an oil-in-water emulsion, preferably contain at least one nonionic oil-in-water emulsifier with an HLB value of more than 7 to 20. These include the emulsifiers that are generally known to those skilled in the art, such as those listed in Kirk-Othmer, Encyclopedia of Chemical Technology, 3rd edition 1979, vol. 8, pages 913-916. For ethoxylated product, the HLB value is calculated according to the formula HLB = (100 - L):5, where L is the amount by weight of the lipophilic groups, i.e., the fatty alkyl or fatty acyl groups in the ethylene oxide adducts, expressed as % by weight. In this context, it may be preferred according to the invention if a water-in-oil emulsifier with an HLB value greater than 1.0 and less than or equal to 7.0 is also used. Especially suitable nonionic surfactants include, for example, silicone copolyols with ethylene oxide units or with both ethylene oxide and propylene oxide units.

[0069] For thickening of the cosmetic agents (M1) used according to the invention, hydrogelforming substances preferably used are those selected from cellulose ethers, especially hydroxyalkyl celluloses, in particular hydroxypropyl cellulose, hydroxypropyl methylcellulose, hydroxyethyl cellulose, carboxymethyl cellulose, cetyl hydroxyethyl cellulose, hydroxybutyl methylcellulose, methyl hydroxyethyl cellulose, in addition, xanthan gum, sclerotium gum, succinoglucans, polygalactomannans, in particular guar gum and locust bean gum, in particular guar gum and locust bean gum per se, and the nonionic hydroxyalkyl guar derivatives and locust bean gum derivatives, such as hydroxypropyl guar, carboxymethyl hydroxypropyl guar, hydroxypropylmethyl guar, hydroxyethyl guar and carboxymethyl guar, also pectins, agar, carrageenan, gum tragacanth, gum arabic, karaya gum, tara gum, gellan, gelatin, casein, propylene glycol alginate, alginic acids and salts thereof, in particular sodium alginate, potassium alginate and calcium alginate, also polyvinyl pyrrolidones, polyvinyl alcohols, polyacrylamides. Especially preferred hydrogel-forming agents are selected from cellulose ethers, especially hydroxyalkyl celluloses, in particular hydroxypropyl cellulose, hydroxypropyl methylcellulose, hydroxyethyl cellulose, carboxymethylcellulose, cetyl hydroxyethyl cellulose, hydroxybutyl methylcellulose and methyl hydroxyethyl cellulose as well as mixtures thereof. However, a lipophilic thickener may also be used. Lipophilic thickeners preferred according to the invention are selected from hydrophobized clay minerals and pyrogenic silicic acids.

[0070] The cosmetic agents (M1) used according to the invention may additionally contain at least one skin-cooling active ingredient. Suitable skin-cooling active ingredients according to the invention include, for example, menthol, isopulegol as well as menthol derivatives, for example, menthyl lactate, menthyl glycolate, menthyl ethyl oxamate, menthyl pyrrolidone carboxylic acid, menthyl methyl ether, menthoxypropanediol, menthone glycerol acetal (9-methyl-6-(1-methylethyl)- 1,4-dioxaspiro(4.5)decan-2-methanol), monomenthyl succinate, 2-hydroxymethyl-3,5,5-trimethyl-cyclohexanol and 5-methyl-2-(1-methylethyl)cyclohexyl-N-ethyloxamate. Menthol, isopulegol, menthyl lactate, menthoxypropanediol menthylpyrrolidone carboxylic acid and 5-methyl-2-(l-methylethyl)cyclohexyl-N-ethyloxamate as well as mixtures of these substances are preferred as the skin-cooling active ingredients, in particular mixtures of menthol and menthyl lactate, menthol, menthol glycolate and menthyl lactate, menthol and menthoxypropanediol or menthol and isopulegol.

[0071] In addition, it may be provided that the cosmetic agents (M1) used according to the invention contain a propellant. In this case, they are preferably packaged as a propellant-driven aerosol. Preferred propellants (propellant gases) include propane, propene, n-butane, isobutane, isobutene, n-pentane, pentene, isopentane, isopentene, methane, ethane, dimethyl ether, nitrogen, air, oxygen, nitrous oxide, 1,1,1,3-tetrafluoroethane, heptafluoro-n-propane, perfluoroethane, monochlorodifluoromethane, 1,1-difluoroethane, tetrafluoropropenes, both individually and in mixtures. Hydrophilic propellant gases such as carbon dioxide, for example, may be used advantageously in the sense of the present invention if the amount of hydrophilic gases is selected to be low and a lipophilic propellant gas (e.g., propane/butane) is present in excess. Especially preferred are propane, n-butane, isobutane as well as mixtures of these propellant gases. It has been found that the use of n-butane as a single propellant gas may be especially preferred according to the invention. The total amount of propellants is 2.0 to 95% by weight, preferably 30 to 85% by weight, in particular 40 to 75% by weight, each based on the total weight of the cosmetic agent (M1) consisting of the components a) and b) described above as well as optionally the additional active ingredients and other ingredients plus the propellant.

[0072] The cosmetic agent (M1) used according to the invention may be applied by various methods. According to a first embodiment, the cosmetic agent (M1) is packaged as a spray application. The spray application is carried out by using a spray device, which contains a filling of the viscous liquid flowable suspension according to the invention or a powdered antiperspirant cosmetic agent into a container. The filling may be under the pressure of a propellant (compressed gas cans, compressed gas packagings, aerosol containers) or it may be a pump atomizer to be operated mechanically without a propellant gas (pump sprays/squeeze bottle). The containers have a dispensing device, preferably in the form of a valve, which enables the removal of the contents as a mist, smoke, foam, powder, paste or stream of liquid. Containers for the spray devices may include in particular cylindrical vessels made of metal (aluminum, tin can, max. capacity preferably 1000 ml_), protected, i.e., shatterproof glass or plastic (max. capacity preferably 220 mL) and/or shattering glass or plastic (capacity preferably 50 to 400 mL). Creamy, gelatinous, pasty and liquid agents may be packaged in pump, spray or squeeze dispenser, in particular also in multichamber pump, multichamber spray or multichamber squeeze dispensers. The packaging for the agents (M1) used according to the invention may be opaque, but it may also be transparent or translucent.

[0073] According to a second embodiment, the cosmetic agent (M1) used according to the invention may be finished in the form of a stick, soft solid, cream, roll-on, dibenzylidene alditol-based gel, loose or compact powder. The formulation of the cosmetic agents (M1) used according to the invention in a certain dosage form, such as, for example, an antiperspirant roll-on, an antiperspirant stick or an antiperspirant gel preferably depends on the requirements of the intended application. Depending on the intended application, the cosmetic agents (M1) used according to the invention may therefore be in solid, semisolid, liquid, dispersed, emulsified, suspended, gelatinous multiphase or powdered form. The concept of liquid also includes in the sense of the present invention any types of solid-state dispersions in liquids. In addition, multiphase cosmetic agents (M1) to be used according to the invention are also understood in the sense of the present invention to include those which have at least two different phases with a phase separation and in which the phases may be arranged horizontally, i.e., one above the other, or vertically, i.e., side by side.

[0074] The substance can be applied with a roller ball application, for example. Such roller balls have a ball mounted in a ball bed, so that the ball can be moved over a surface. In doing so, the ball picks up some of the cosmetic agent (M1) to be distributed according to the invention and conveys it to the surface to be treated. The packaging for these agents may be transparent, translucent or opaque, as indicated above.

[0075] In addition, it is also possible to apply the cosmetic agents (M1) used according to the invention by means of a solid stick in the form of a solid emulsion, a solid wax dispersion or a solid soap gel.

[0076] According to a third embodiment, the cosmetic agent (M1) used according to the invention may be present in and/or on a disposable substrate selected from the group of cloths, pads and sachets. Especially preferred are moist cloths, i.e., prepackaged moist cloths, preferably packaged individually for the user, such as those familiar from the field of cleaning glass or from the field of moist toilet paper, for example. Such moist cloths, which may advantageously also contain preservatives, are impregnated or treated with a cosmetic agent (M1) used according to the invention and are preferably packaged individually. They may be used as a deodorant cloth, for example, which is of particular interest for use in transit. Preferred substrate materials are selected from porous flat cloths. They may be made of a fibrous or cellular flexible material, which has adequate mechanical stability, while at the same time having softness for use on the skin. These cloths include cloths made of woven and nonwoven synthetic and natural fibers, felt, paper or foam, such as hydrophilic polyurethane foam. Preferred deodorant or antiperspirant substrates according to the invention can be obtained by soaking or impregnating or by melting the cosmetic agent (M1) used according to the invention on a substrate.

[0077] The following table shows especially preferred embodiments AF1 through AF356 of the cosmetic agents (M1) used according to the invention (all amounts are given in percent by weight and are based on the total weight of the propellant-free cosmetic agent (M1).

u selected from aqueous, aqueous-alcoholic and water-free carriers, 2) contains - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 1.0 to 1.4 mol%, histidine in an amount of 2.0 to 2.4 mol% and arginine in an amount of 1.8 to 2.2 mol%, 3) contains - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 5.8 to 6.2 mol%, histidine in an amount of 2.0 bis 2.4 mol% and arginine in an amount of 5.4 to 6.0 mol%, 4) contains - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 4.8 to 5.2 % by weight, histidine in an amount of 2.0 to 2.4 % by weight and arginine in an amount of 7.8 to 8.2 % by weight, 5) contains - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 1.0 to 1.4 mol%, histidine in an amount of 2.0 to 2.4 mol%, arginine in an amount of 1.8 to 2.2 mol% and has an average molecular weight Mw of 300 to 5,000 Da, 6) contains - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 5.8 to 6.2 mol%, histidine in an amount of 2.0 to 2.4 mol%, arginine in an amount of 5.4 to 6.0 mol% and has an average molecular weight Mw of 300 to 5,000 Da, 7) contains - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 4.8 to 5.2 % by weight, histidine in an amount of 2.0 to 2.4 % by weight, arginine in an amount of 7.8 to 8.2 % by weight and has an average molecular weight Mw of 300 to 5,000 Da, 8) hydrophobically and/or anionically and/or cationically modified rice protein hydrolysate, 9) hydrophobically and/or anionically and/or cationically modified pea protein hydrolysate, 10) hydrophobically and/or anionically and/or cationically modified hydrolyzed keratin, 11) hydrophobically and/or anionically and/or cationically modified wheat protein hydrolysate, 12) hydrophobically and/or anionically and/or cationically modified soy protein hydrolysate, 13) hydrophobically and/or anionically and/or cationically modified protein hydrolysate from seeds of Adansonia digitata [0078] Embodiments AF1 through AF356 preferably contain at least one compound selected from (i) triethyl citrate; (ii) 3-(2-ethylhexyloxy)-1,2-propanediol; (iii) mixtures of 2-benzylheptan-1-ol and phenoxyethanol; (iv) cocamidopropyl PG-dimonium chloride phosphate; (v) silver lactate; (vi) cetyl pyridinium chloride; (vii) benzalkonium chloride; (viii) benzethonium chloride; (ix) polyglyceryl-2-caprate; (x) capryl hydroxamic acid as well as (xi) mixtures thereof.

[0079] Use of embodiments 1 through 176 of the cosmetic agents (M1) listed above in the methods according to the invention leads to an excellent deodorant effect, which also lasts a long time.

[0080] A second subject matter of the present invention is the use of at least one protein hydrolysate selected from the group of wheat protein hydrolysates, soy protein hydrolysates, rice protein hydrolysates, pea protein hydrolysates, hydrolyzed keratin, protein hydrolysates from the seeds of Adansonia digitata as well as mixtures thereof for reducing the body odor triggered by perspiration.

[0081] With respect to additional preferred embodiments of the use according to the invention with respect to the protein hydrolysates in particular, what was said above about the method according to the invention, in particular about the cosmetic agents (M1) used there also applies, mutatis mutandis.

[0082] The following examples illustrate the present invention without limiting it to these examples. Examples 1. Odor-inhibiting effect [0083] A filter paper is placed in a glass with a screw-on lid (1 liter). 15 pl_ portions of a highly diluted solution of the odor-forming components are applied to the filter paper: - Sweat odor no. 45: volatile short-chain linear and/or branched, saturated and/or unsaturated fatty acid (including 3-methyl-2-hexenoic acid) - Sweat odor no. 50: volatile short-chain linear and/or branched, saturated and/or

unsaturated fatty acid (including 3-hyddroxy-3-methylhexanoic acid) - stored in glass at 37°C - Sweat odor no. 48: short-chain sulfanyl alcohols (including 3-sulfanyl-3-methylhexanol) [0084] Then one each of the compositions presented in the tables below (all amounts given in% by weight, unless otherwise indicated) is applied to the filter paper. After storing the samples for 24 hours at room temperature and/or at 37°C, the intensity of the odor is evaluated olfactorily by trained evaluators and ranked according to a scale from 0 to 4 (0 = no odor, 1 = weak odor, 2 = average odor intensity, 3 = intense odor, 4 = very intense odor).

υ Preferably selected from hydrolyzed wheat protein with an average molecular weight Mw of 300 to 5000 Da [0085] The following evaluations were obtained (average of all evaluations):

[0086] By using certain protein hydrolysates, a significant reduction in unpleasant body odors can be achieved with a roll-on formulation. 2. Cosmetic agents (M1) that can be used in the methods according to the invention: [0087] Sprayable translucent antiperspirant microemulsions (amounts in percent by weight, based on the total weight of the propellant-free emulsion)

[0088] The microemulsions 1.1 to 1.6 are used with a suitable spray system from a pressurized container (aerosol). Suitable propellants include air, nitrous oxide, nitrogen, C02 and other compressible gases.

[0089] Antiperspirant emulsion (O/W) (amounts in percent by weight, based on the total weight of the propellant-free emulsion)

[0090] Emulsions 2.1 to 2.3 are each used with a suitable spray system from a pressurized container (aerosol) using air, nitrous oxide, nitrogen, C02 and other compressible gases as the propellant.

[0091] Deodorant (amounts in percent by weight, based on the total weight of the propellant-free deodorant)

[0092] Deodorants 3.1 to 3.3 are each used with a suitable spray system from a pressurized container (aerosol). The propellants used include air, nitrous oxide, nitrogen, C02 and other compressible gases.

[0093] Water-in-oil emulsions used according to the invention (amounts given in% by weight, based on the total weight of the water-in-oil emulsions without propellant)

[0094] Emulsions 4.1 to 4.3 are each used with a suitable spray system from a pressurized container (aerosol), with 15, 20, 25 or 30% of the respective emulsions being jointly to the aerosol container to the aerosol container with 85%; 80%; 75% or 70% of a suitable propellant gas, for example, a propane/butane/isobutane mixture (1.6 to 3.8 bar pressure).

[0095] Emulsion according to the PIT method (based on the total weight of the propellant-free emulsion):

[0096] Emulsions 5.1 to 5.3 are each applied using a suitable spray system from a pressurized container (aerosol), using air, laughing gas, nitrogen, C02 and other compressible gases as propellants.

[0097] Antiperspirant sticks in the form of an oil-in-water emulsion used according to the invention (amounts in percent by weight)

[0098] Antiperspirant emulsion (O/W) (amounts in percent by weight) used according to the invention

[0100] Emulsions 7.1 to 7.3 were each poured into a roll-on applicator.

[0101] Anhydrous surfactant-containing antiperspirant sticks (amounts in percent by weight)

[0102] Anhydrous surfactant-containing antiperspirant sticks (amounts in percent by weight)

* Number-average particle size 3-20 pm [0103] Sprayable translucent antiperspirant microemulsions (amounts in percent by weight)

[0104] Soap-containing deodorant sticks (amounts in percent by weight)

[0105] Deodorant in pump atomizer (amounts in percent by weight)

[0106] Antiperspirant roll-on (amounts in percent by weight)

[0107] Water-in-oil emulsions used according to the invention (amounts in percent by weight)

[0108] Cloths (examples nos. 14.1-14.4) [0109] For the antiperspirant cloths used according to the invention, the single layer substrate of 100% viscose with a weight of 50 g/m2 was treated with 75 g of the exemplary emulsions 8.1 and/or 8.2 per square meter or with 75 g each of the exemplary compositions 13.1 and/or 13.2, cut into cloths of a suitable size and packaged in sachets.

[0110] Antiperspirant cosmetic agents used according to the invention in the form of a water-in-oil emulsion (amounts in percent by weight)

[0111] Antiperspirant cosmetic agents used according to the invention (amounts in percent by weight)

[0112] Emulsion according to the PIT method (amounts in percent by weight)

[0113] Antiperspirant roll-on (amounts in percent by weight)

[0114] Antiperspirant cream (amounts in percent by weight)

[0115] Anhydrous deodorant sprays (amounts in percent by weight)

[0116] Antiperspirant spray of the suspension type (amounts in percent by weight)

[0117] The following commercial products were used:

Claims (14)

1. Cosmetic method for reducing the body odor caused by perspiration in which a cosmetic agent (M1) is applied to human skin and remains at the application site for at least one hour, wherein the antiperspirant cosmetic agent (M1) contains, in a cosmetically tolerable vehicle: a) at least one protein hydrolysate selected from the group of wheat protein hydrolysates, soy protein hydrolysates, rice protein hydrolysates, pea protein hydrolysates, hydrolyzed keratin, protein hydrolysates from the seeds of Adansonia digitata as well as mixtures thereof, and b) at least one active ingredient selected from the group of deodorant active ingredients, antiperspirant aluminum salts, antiperspirant aluminum zirconium salts as well as mixtures thereof.

2. Method according to claim 1, characterized in that the cosmetic agent (M1) contains at least one wheat protein hydrolysate - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 1.0 to 1.4 mol%, histidine in an amount of 2.0 to 2.4 mol% and arginine in an amount of 1.8 to 2.2 mol%.

3. Method according to any one of claims 1 or 2, characterized in that the cosmetic agent (M1) contains at least one soy protein hydrolysate - based on the total amount of amino acids of the hydrolysate - lysine in an amount of 5.8 to 6.2 mol%, histidine in an amount of 2.0 to 2.4 mol% and arginine in an amount of 5.4 to 6.0 mol%.

4. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains the at least one protein hydrolysate from seeds of Adansonia digitata -based on the total weight of amino acids of the hydrolysate - lysine in a total amount of 4.8 to 5.2% by weight, histidine in a total amount of 2.0 to 2.4% by weight and arginine in a total amount of 7.8 to 8.2% by weight

5. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains at least one protein hydrolysate with an average molecular weight Mw of 150 to 100,000 Da, preferably 180 to 50,000 Da, more preferably 200 to 10,000 Da, even more preferably from 250 to 8000 Da, in particular from 300 to 5000 Da.

6. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains at least one protein hydrolysate with an isoelectric point of pH 3.0 to pH 10.0, preferably pH 3.0 to pH 9.5, in particular pH 3.0 to pH 8.0.

7. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains - based on its total weight - the at least one protein hydrolysate, in particular the wheat protein hydrolysate and/or soy protein hydrolysate and/or rice protein hydrolysate and/or pea protein hydrolysate and/or hydrolyzed keratin and/or protein hydrolysate from seeds of Adansonia digitata, in a total amount of 1.0 to 40% by weight, preferably of 2.0 to 35% by weight, more preferably of 2.0 to 30% by weight, in particular of 2.0 to 20% by weight.

8. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains at least one deodorant active ingredient selected from the group of (i) silver and/or zinc salts, in particular silver lactate, zinc phenol sulfonate and zinc hydroxide carbonate; (ii) aromatic alcohols in particular 2-benzylheptan-1-ol and tropolone as well as mixtures of 2-benzylheptan-1-ol and phenoxyethanol; (iii) 1,2-alkanediols with 5 to 12 carbon atoms, in particular 3-(2-ethylhexyloxy)-1,2-propanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol as well as mixtures of 1,2-hexanediol and 1,2-octanediol; (iv) triethyl citrates; (v) active ingredients against exoesterases, in particular against aryl sulfatase, lipase, beta-glucuronidase and cystathione-p-lyase; (vi) cationic phospholipids, in particular cocamidopropyl PG-dimonium chloride phosphate; (vii) odor absorbers, in particular silicates such as montmorillonite, kaolinite, ilite, beidellite, nontronite, saponite, hectorite, bentonite, smectite and talc, zeolites, zinc ricinoleate, cyclodextrins, magnesium oxide; (viii) deodorant ion exchangers; (ix) antimicrobial agents, in particular cetyl pyridinium chloride, benzalkonium chloride, benzethonium chloride, tartaric acid, carnosic acid, polyglyceryl 2-caprate; (x) prebiotic components; (xi) chelating agents, in particular capryl hydroxamic acid; (xii) sorbitan caprylate and/or glucono-delta-lactone as well as (xi) mixtures thereof.

9. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains at least one deodorant active ingredient - based on the total weight of the cosmetic agent (M1) - in a total amount of 0.0005 to 20% by weight, preferably 0.1 to 10% by weight, more preferably of 0.1 to 10% by weight, in particular 0.1 to 2.0% by weight.

10. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains at least one antiperspirant aluminum salt selected from the group of (i) water-soluble astringent inorganic salts of aluminum, in particular aluminum chlorohydrate, aluminum sesquichlorohydrate, aluminum dichlorohydrate, aluminum hydroxide, potassium aluminum sulfate, aluminum bromohydrate, aluminum chloride, aluminum sulfate; (ii) water-soluble astringent organic salts of aluminum, in particular aluminum chlorohydrex propylene glycol, aluminum chlorohydrex polyethylene glycol, aluminum propylene glycol complex, aluminum sesquichlorohydrex propylene glycol, aluminum sesquichlorohydrex polyethylene glycol, aluminum propylene glycol dichlorohydrex, aluminum polyethylene glycol dichlorohydrex, aluminum undecylenoyl collagen amino acid, sodium aluminum lactate, sodium aluminum chlorohydroxylactate, aluminum lipoamino acids, aluminum lactate, aluminum chlorohydroxyallantoinate, sodium aluminum chlorohydroxylactate; as well as (iii) mixtures thereof.

11. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains at least one antiperspirant aluminum zirconium salt selected from the group of (i) water-soluble astringent inorganic aluminum zirconium salts, in particular aluminum zirconium trichlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium pentachlorohydrate, aluminum zirconium octachlorohydrate; (ii) water-soluble astringent organic aluminum zirconium salts, in particular aluminum zirconium propylene glycol complexes, aluminum zirconium trichlorohydrex glycine, aluminum zirconium tetrachlorohydrex glycine, aluminum zirconium pentachlorohydrex glycine, aluminum zirconium octachlorohydrex glycine; as well as (iii) mixtures thereof.

12. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) contains the at least one antiperspirant aluminum salt and/or aluminum zirconium salt - based on the total weight of the cosmetic agent (M1) - in a total amount of 0.1 to 35% by weight, preferably of 0.5 to 25% by weight, more preferably of 1.0 to 15% by weight, even more preferably of 1.5 to 10% by weight, in particular of 2.0 to 8.0% by weight.

13. Method according to any one of the preceding claims, characterized in that the cosmetic agent (M1) additionally contains at least one hydrolyzed starch.

14. Use of at least one protein hydrolysate selected from the group of wheat protein hydrolysates, soy protein hydrolysates, rice protein hydrolysates, pea protein hydrolysates, hydrolyzed keratin, protein hydrolysates from the seeds of Adansonia digitata as well as mixtures thereof, for reducing the body odor caused by perspiration.