GB2551230A

GB2551230A - Cosmetic agent comprising a combination of two mutually different active agents

Info

Publication number: GB2551230A
Application number: GB1621418.1A
Authority: GB
Inventors: Banowski Bernhard; Simmering Rainer; Doring Thomas; Breuer Imme; Rauschenberg Melanie
Original assignee: Henkel AG and Co KGaA
Current assignee: Henkel AG and Co KGaA
Priority date: 2015-12-18
Filing date: 2016-12-16
Publication date: 2017-12-13
Also published as: FR3045340A1; GB201621418D0; DE102015225958A1

Abstract

A cosmetic agent comprises a combination of at least one active substance (A) and an active substance (B). Substance (A) is selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, phosphates, alkanediols with 6 to 10 carbon atoms (such as 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol), tropolone, silver salts, alkaline earth oxides (such as magnesium oxide), aluminium salts (such as aluminium chlorohydrate), aluminium/zirconium salts (such as aluminium-zirconium tetrachlorohydrex glycine), as well as mixtures thereof. Substance (B) is selected from the group of quaternary ammonium compounds (such as cetylpyridinium chloride, benzalkonium chloride, or benzethonium chloride), zinc salts (such as zinc hydroxide carbonate or zinc phenolsulphonate), polyglycerol esters (such as polyglyceryl-2-caprate), sorbitan esters (such as sorbitan caprylate), octenidine, carnosic acid, tartaric acid, and mixtures thereof. The agent may also comprise also at least one deodorant agent (C). The combination may be used in the prevention of body odour and also as an antiperspirant.

Description

“Cosmetic agent comprising a combination of two mutually different active agents” [0001] The present application relates to cosmetic agents containing a combination of at least two active substances. These cosmetic agents have an outstanding deodorizing and/or antiperspirant effect that also persists over a long period of time.

[0002] Moreover, the present invention relates to a method for reducing and/or preventing body odor triggered by perspiration and/or body perspiration perse, in which a cosmetic agent according to the invention is applied to the skin and remains there for at least one hour.

[0003] Finally, the present invention relates to the use of a cosmetic agent according to the invention to reduce and/or prevent body odor triggered by perspiration and/or the body perspiration per se.

[0004] Eccrine and apocrine sweat glands are present in the human armpit. While the eccrine glands produce an aqueous secretion in response to heat, the apocrine glands can produce a viscous secretion in response to stress. This apocrine sweat represents a complex mixture containing, among other things, steroids, cholesterol and other fats as well as about 10% proteins. Through the bacterial decomposition of the ingredients of the apocrine sweat, an unpleasant body odor develops under the armpit from the initially odorless secretion.

[0005] The decomposition products of the apocrine sweat, which make a substantial contribution to body odor, particularly to axillary body odor, can be divided up into three classes: the first class is formed by short-chain C4-C10 fatty acids, which can be linear, branched, saturated or unsaturated (for example, isovaleric acid, 3-methyl-2-hexenoic acid, 3-hydroxy-3-methylhexanoic acid); the second class is formed by short-chain linear or branched sulfanyl alcohols; and the third class consists of various steroid hormones and metabolic products thereof (for example, 5-a-androstenol and 5-a-androstenone).

[0006] Body odor can thus be combated by preventing bacterial build-up in the sweat or by using perfume to mask the body odor. To prevent bacterial build-up in the sweat, antimicrobial substances are used in the prior art that reduce the number of sweat-decomposing bacteria on the skin by killing them or inhibiting the growth of these bacteria. Moreover, active substances are known which reduce and/or prevent the creation of decomposition products by blocking bacterial enzymes. In addition, it is also known to absorb the volatile decomposition products through physical and/or chemical interaction, thereby preventing unpleasant body odor. Furthermore, the occurrence of body perspiration can also be reduced through the use of antiperspirant agents, so that fewer or no decomposition products can be formed by the sweat-decomposing bacteria.

However, there continues to be a need for cosmetic agents having both a high-level and long-lasting deodorizing and/or antiperspirant effect.

[0007] It was therefore the object of the present invention to provide cosmetic agents that result in a good and long-lasting effect against body odor and perspiration. Moreover, the occurrence of skin inflammation and/or irritation during and/or after use of the cosmetic agent according to the invention is to be avoided. In addition, the cosmetic agents are to have a high level of storage stability as well as good cosmetic characteristics.

[0008] Surprisingly, it was found that, through the use of a combination of at least two active substances, it is possible not only to specifically combat the odor-causing bacteria and achieve an outstanding antiperspirant effect, but rather also to achieve an unexpectedly long deodorizing and/or antiperspirant effect. Through the synergistic effect of the two abovementioned components of the cosmetic agents according to the invention, the quantity of active substances can be reduced without having a negative impact on the deodorizing and/or antiperspirant effect. Due to the reduced quantity of active substances, the cosmetic agents according to the invention are low-irritant and low-sensitizing. Moreover, the use of the combination of active substances does not have a negative impact on the storage stability of the cosmetic agents according to the invention, so these agents have outstanding storage stability. Finally, these agents have good cosmetic characteristics.

[0009] An object of the present application is therefore a cosmetic agent containing, in a cosmetically acceptable carrier, a) at least one active substance (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, phosphates, alkanediols with 6 to 10 carbon atoms, tropolone, silver salts, alkaline earth oxides, aluminum salts, aluminum/zirconium salts, as well as mixtures thereof, and b) at least one second active substance (B), selected from the group of quaternary ammonium compounds, zinc salts, polyglycerol esters, sorbitan esters, octenidine, carnosic acid, tartaric acid, as well as mixtures thereof.

[0010] Through the use of a combination of at least one first active substance (A) and at least one second active substance (B), the outstanding reduction of the body odor triggered by perspiration, particularly of the body odor under the axilla, and/or of the body perspiration, particularly under the axilla, is achieved. In addition, it was found that the previously mentioned combination of the two components a) and b) of the cosmetic agents according to the invention results in a synergistic increase in the deodorizing and/or antiperspirant performance, so that the quantity of active substances can be reduced without negatively impacting the deodorizing and/or antiperspirant effect. Due to the reduced quantity of active substances, the cosmetic agents according to the invention have improved skin tolerance. What is more, through the use of the previously mentioned combination of active substances, the cosmetic characteristics of the cosmetic agents according to the invention can be improved. Finally, the use of components a) and b) does not have a negative impact on the storage stability of the cosmetic agents according to the invention.

[0011] According to the invention, the term “antiperspirant” is understood as the diminishing or reduction of the transpiration of the body’s sweat glands.

[0012] Moreover, the term “aluminum salts and aluminum/zirconium salts” are understood in relation to the present invention particularly as being chlorides, bromides and iodides of aluminum and/or of zirconium as well as compounds of the formulas AI(OH)yX and Zr(OH)zX, with X standing for a halogenide ion in the aforementioned formulas.

[0013] In addition, the term “fatty acid” as it is used in relation to the present invention refers to aliphatic carboxylic acids having unbranched or branched carbon groups with 4 to 40 carbon atoms. The fatty acids used in relation to the present invention can be both naturally occurring and synthetically manufactured fatty acids. Moreover, the fatty acids can be mono- or polyunsaturated.

[0014] Finally, in relation to the present invention, the term “fatty alcohol” is to be understood as aliphatic, monovalent, primary alcohols having unbranched or branched hydrocarbon groups with 4 to 40 carbon atoms. The fatty alcohols used in the context of the invention can also be mono- or polyunsaturated.

[0015] Unless indicated otherwise, the signifier wt% refers herein to the total weight of the cosmetic agents according to the invention, with the sum of all ingredients of the agents according to the invention yielding 100 wt%. Furthermore, the signifier wt%, unless indicated otherwise, refers to the quantity of the respective component in the propellant-free cosmetic agent, so that the quantity of any propellant that is present is not considered in the calculation of the total weight of the cosmetic agents.

[0016] The cosmetic agent contains components a) and b) in a cosmetically acceptable carrier. The carrier preferably contains at least one component selected from water, a (^-04 alcohol, a cosmetic oil that is a liquid under normal conditions, and mixtures thereof. The cosmetic oils that are liquid under normal conditions are not miscible with water and are neither odorants nor essential oils. In terms of the present application, “normal conditions” are a temperature of 20°C and a pressure of 1,013 hPa.

[0017] Examples of suitable cosmetic carriers are aqueous or aqueous-alcoholic carriers. These refer to carriers that contain greater than 5.0 wt% water or greater than 5.0 wt% water as well as at least one CrC+alcohol, each with respect to the total weight of the cosmetic agent. Aqueous carriers preferably contain free water in a total quantity of 10 to 96 wt%, preferably 15 to 80 wt%, more preferably 30 to 70 wt%, particularly 40 to 60 wt% with respect to the total weight of the cosmetic agent. Aqueous-alcoholic carriers preferably contain ethanol in a total quantity of 0.1 to 50 wt%, preferably 0.5 to 30 wt%, more preferably 1.0 to 20 wt%, particularly 1.0 to 9.0 wt% with respect to the total weight of the cosmetic agent.

[0018] The previously mentioned aqueous and aqueous-alcoholic carriers can also contain at least one (C2-C6)-alkyl alcohol with 2 or 3 hydroxy groups, particularly 1,2-propylene glycol, 1,3-propylene glycol, glycerin and 1,3-butylene glycol.

[0019] However, a provision can also be made to use a water-free cosmetic carrier. According to the invention, water-free carriers are understood as carriers containing less than 5.0 wt%, preferably less than 4.0 wt%, more preferably less than 3.0 wt%, particularly 0 wt% free water with respect to the total weight of the cosmetic agent. In terms of the present invention, free water is understood as water that is different from water of crystallization, hydration water, or similar molecularly bound water of the components used. However, water of crystallization, hydration water or similar molecularly bound water of the components is not considered in the calculation of the total quantity of free water.

[0020] In this context, alcoholic media in particular are used as cosmetically acceptable carriers. The lower alcohols with 1 to 4 carbon atoms that are usually used for cosmetic purposes, such as ethanol and isopropyl, for example, can be particularly used as alcohols. Alcoholic carriers preferably contain ethanol in a total quantity of 20 to 95 wt%, more preferably 25 to 65 wt%, particularly 25 to 60 wt% with respect to the total weight of the cosmetic agent.

[0021] Furthermore, it is especially preferred in this context that liquid cosmetic oils be used as cosmetic carriers. These cosmetic oils can be selected from the group of (i) volatile non-silicone oils, particularly liquid paraffin oils and isoparaffin oils, such as isodecane, isoundecane, isododecane, isotridecane, isotetradecane, isopentadecane, isohexadecane and isoeicosane; (ii) nonvolatile non-silicone oils, particularly the esters of linear or branched saturated or unsaturated C2-30 fatty alcohols with linear or branched saturated or unsaturated C2.30 fatty acids, which can be hydroxylated, the C8-C22 fatty alcohol esters of mono- or polyvalent C2-C7 hydroxycarboxylic acids, the dicarboxylic acid esters of linear or branched C2-C10 alkanols, the addition products of ethylene oxide and/or propylene oxide on mono- or polyvalent C3.22 alkanols, which can be optionally esterified, the symmetrical, asymmetrical or cyclic esters of carbonic acid with fatty alcohols, the esters of dimers of unsaturated C12.22 fatty acids with monovalent, linear, branched and cyclic C2_i8 alkanols or C2.6 alkanols, the benzoic acid esters of linear or branched C8_22 alkanols, such as benzoic acid C1215 alkyl ester and benzoic acid isostearyl esters and benzoic acid octyldodecyl ester, the synthetic hydrocarbons, such as polyisobutene and polydecene, the alicyclic hydrocarbons; and (iii) mixtures thereof.

[0022] According to the invention, the term “volatile cosmetic oil” refers to cosmetic oils which, at 20°C and an ambient pressure of 1,013 hPa, have a vapor pressure from 2.66 to 40,000 Pa (0.02 to 300 mm Hg), preferably from 10 to 12,000 Pa (0.1 to 90 mm Hg), more preferably from 13 to 3,000 Pa (0.1 to 23 mm Hg), particularly from 15 to 500 Pa (0.1 to 4 mm Hg). Moreover, in terms of the present invention, the term “nonvolatile cosmetic oils” is understood as referring to cosmetic oils which, at 20°C and an ambient pressure of 1,013 hPa, have a vapor pressure of less than 2.66 Pa (0.02 mm Hg).

[0023] The use of mixtures of the abovementioned cosmetic oils is also preferred according to the invention, particularly nonvolatile and volatile cosmetic oils, since they enable parameters such as feel on the skin, visibility of the residue and stability of the cosmetic agent according to the invention to be adjusted, thereby better adapting the agent to consumers’ needs.

[0024] In relation to the present invention, it is preferred if the cosmetic oil, which is liquid at 20°C and 1.013 hPa, is used in a total quantity of 1.0 to 98 wt%, preferably 2.0 to 95 wt%, more preferably 5.0 to 70 wt%, even more preferably 10 to 60 wt%, particularly 15 to 50wt%, with respect to the total weight of the cosmetic agent.

[0025] As the first essential component a), the cosmetic agent according to the invention contains at least one active substance (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, phosphates, alkanediols with 6 to 10 carbon atoms, tropolone, silver salts, alkaline earth oxides, aluminum salts, aluminum/zirconium salts, as well as mixtures thereof.

[0026] The cosmetic agents according to the invention can contain certain aluminum salts. It is therefore preferred in relation to the present invention if the cosmetic agent contains at least one aluminum salt selected from the group of (i) water-soluble inorganic salts of aluminum, particularly aluminum chlorohydrate, aluminum sesquichlorohydrate, aluminum dichlorohydrate, aluminum hydroxide, potassium aluminum sulfate, aluminum bromohydrate, aluminum chloride, aluminum sulfate; (ii) water-soluble organic salts of aluminum, particularly aluminum chlorohydrex propylene glycol, aluminum chlorohydrex polyethylene glycol, aluminum propylene glycol complexes, aluminum sesquichlorohydrex propylene glycol, aluminum sesquichlorohydrex polyethylene glycol, aluminum propylene glycol dichlorohydrex, aluminum polyethylene glycol dichlorohydrex, aluminum undecylenoyl collagen amino acid, sodium aluminum lactate, sodium aluminum chlorohydroxy lactate, aluminum lipoamino acids, aluminum lactate, aluminum chlorohydroxy allantoinate, sodium aluminum chlorohydroxy lactate; and (iii) mixtures thereof.

[0027] Moreover, the cosmetic agents according to the invention can contain special aluminum-zirconium salts. Preferred embodiments are therefore characterized in that the cosmetic agent contains at least one aluminum-zirconium salt selected from the group of (i) water-soluble inorganic aluminum-zirconium salts, particularly aluminum zirconium trichlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium pentachlorohydrate, aluminum zirconium octachlorohydrate; (ii) water-soluble organic aluminum-zirconium salts, particularly aluminum zirconium propylene glycol complexes, aluminum zirconium trichlorohydrex glycine, aluminum zirconium tetrachlorohydrex glycine, aluminum zirconium pentachlorohydrex glycine, aluminum zirconium octachlorohydrex glycine; and (iii) mixtures thereof.

[0028] According to the invention, the terms “aluminum salts” and “aluminum-zirconium salts” are not understood as referring to any aluminosilicates and zeolites. Furthermore, water-soluble aluminum salts and water-soluble aluminum-zirconium salts are understood as being such salts which have a solubility of at least 3 wt% at 20°C, that is, at least 3 g of the antiperspirant aluminum salt or aluminum-zirconium salt dissolve in 97 g water at 20°C.

[0029] Especially preferred inorganic aluminum salts are selected from among aluminum ch loro hydrate, particularly aluminum chlorohydrate with the general formula [AI2(OH)5CI · 1-6 H20]n, preferably [AI2(OH)5CI 2-3 H20]n, which can be present in non-activated (polymerized) or in activated (depolymerized) form, as well as aluminum chlorohydrate with the general formula [AI2(OH)4CI2 1-6 H20]n, preferably [AI2(OH)4CI2 · 2-3 H20]n, which can be present in non-activated (polymerized) or in activated (depolymerized) form.

[0030] Antiperspirant aluminum salts that are especially preferred according to the invention are selected from so-called “activated” aluminum salts, which are also referred to as antiperspirant agents “with enhanced activity.” Such active substances are known in the prior art and also commercially available. Activated aluminum salts are generally produced by heat-treating a diluted solution of the corresponding salt (e.g., a solution with 10 wt% salt) in order to enlarge its HPLC peak 4 to peak 3 area ratio. The activated salt can then be dried, particularly spray-dried, into a powder. Besides spray-drying, roller-drying is also suitable, for example. Activated aluminum salts typically have an HPLC peak 4 to peak 3 area ratio of at least 0.4, preferably at 0.7, particularly at least 0.9, with at least 70% of the aluminum being attributable to these HPLC peaks.

[0031] In this connection, “activated” aluminum-zirconium salts are also known which have a high HPLC peak 5 aluminum content, particularly a peak 5 area of at least 33%, preferably at least 45%, with respect to the entire area under peaks 2 to 5, measured with HPLC on a 10 wt% aqueous solution of the active substance under conditions in which the aluminum species are resolved in at least 4 successive peaks (designated as peaks 2 to 5). Moreover, the abovementioned activated aluminum-zirconium salts can be additionally stabilized with a water-soluble strontium salt and/or with a water-soluble calcium salt.

[0032] It is also possible according to the invention to use antiperspirant aluminum salts as nonaqueous solutions or solubilizates of an activated antiperspirant aluminum or aluminum-zirconium salt. Such aluminum or aluminum-zirconium salts are stabilized against the loss of the activation of the salt through the addition of an effective quantity of a polyvalent alcohol having 3 to 6 carbon atoms and 3 to 6 hydroxyl groups, preferably propylene glycol, sorbitol and pentaerythritol.

[0033] Complexes of activated antiperspirant aluminum or aluminum-zirconium salts with a polyvalent alcohol are especially preferred which contain 20 to 50 wt%, preferably 20 to 42 wt%, activated antiperspirant aluminum or aluminum-zirconium salt and 2 to 16 wt% molecularly bound water, with the remainder to 100 wt% being at least one polyvalent alcohol with 3 to 6 carbon atoms and 3 to 6 hydroxyl groups. Propylene glycol, propylene glycol/sorbitol mixtures and propylene glycol/pentaerythritol mixtures are preferred such alcohols.

[0034] In the framework of the present invention, it is also possible to use basic calcium-aluminum salts as antiperspirant aluminum salts. These salts can be obtained through the conversion of calcium carbonate with aluminum chlorhydroxide or aluminum chloride and aluminum powder or through the addition of calcium chloride dihydrate to aluminum chlorhydroxide. However, it is also possible to use aluminum-zirconium complexes that are buffered with salts of amino acids, particularly with alkaline and alkaline earth glycinates.

[0035] According to the invention, activated aluminum or aluminum-zirconium salts that are preferably stabilized by amino acids, particularly glycine, hydroxyalkanoic acids, particularly glycolic acid and lactic acid, or betaines, can also be used as preferred antiperspirant activated aluminum or aluminum-zirconium salts.

[0036] Other preferred activated aluminum salts are those of the general formula AI2(OH)6-aXa, where X stands for Cl, Br, I or N03 and "a" stands for a number from 0.3 to 5, preferably from 0.8 to 2.5, particularly from 1 to 2, so that the molar ratio of AI:X is 0.9:1 to 2.1:1. Aluminum chlorohydrate (i.e., X stands for Cl in the above formula) is especially preferred, particularly 5/6-basic aluminum chlorohydrate where "a" = 1, so that the molar ratio of aluminum to chlorine is 1.9:1 to 2.1:1.

[0037] Preferred activated aluminum-zirconium salts are those of the general formula ZrO(OH)2. pbYb, where Y stands for Cl, Br, I, N03 or S04, b stands for a rational number from 0.8 to 2, and p stands for the valence of Y, so that the AI:Zr molar ratio is from 2 to 10 and the metal:(X+Y) ratio is from 0.73 to 2.1, preferably from 0.9 to 1.5. One especially preferred salt is aluminum zirconium chlorohydrate (i.e., X and Y stand for Cl), which has an AI:Zr ratio of 2 to 10 and a molar metal:CI ratio of 0.9 to 2.1.

[0038] Antiperspirant aluminum salts that are especially preferred according to the invention have a molar metal-to-chloride ratio of 1.9 to 2.1. The metal-to-chloride ratio of aluminum sesquichlorohydrates that are also especially preferred in the context of the invention is 1.5:1 to 1.8:1. Preferred aluminum zirconium tetrachlorohydrates have a molar ratio of AI:Zr from 2 to 6 and of metal:chloride from 0.9 to 1.3, with salts with a molar metal-to-chloride ratio of 0.9 to 1.1, preferably 0.9 to 1.0 being particularly preferred.

[0039] In relation to the present invention, it is preferred if certain active substances (A) are used. Preferred embodiments of the present invention are therefore characterized in that the cosmetic agent contains at least one first active substance (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum chlorohydrate, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. The use of these active substances (A) has proven to be especially advantageous in combination with the second active substance (B) in terms of deodorizing and/or antiperspirant performance. In particular, a synergistic increase in the deodorizing and/or antiperspirant performance is achieved. Moreover, through the use of these active substances (A), both the skin tolerance and the cosmetic characteristics of the agents according to the invention can be further increased. These compounds have the following chemical names and CAS numbers:

[0040] The deodorizing and/or antiperspirant effect can be further increased if the cosmetic agents contain more than one of the active substances (A) listed above. Preferred cosmetic agents are therefore characterized in that they contain at least two active substances (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum chlorohydrate, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof.

[0041] Other preferred cosmetic agents according to the invention are characterized in that they contain at least three active substances (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum chlorohydrate, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof.

[0042] The cosmetic agents according to the invention preferably contain the first active substance (A) in certain quantity ranges. Preferred cosmetic agents according to the invention are therefore characterized in that they contain—with respect to their total weight—0.0005 to 35 wt%, preferably 0.005 to 25 wt%, more preferably 0.01 to 10 wt%, particularly 0.05 to 8.0 wt%, of at least one first active substance (A). The use of such quantities of the at least one first active substance (A) in combination with the second active substance (B) results in a synergistic increase in the deodorizing and/or antiperspirant performance. In this way, the quantity of active substances used can be reduced without negatively impacting the deodorizing and/or antiperspirant performance. The cosmetic agents according to the invention are therefore especially skin-friendly. In addition, the use of the abovementioned quantities of the first active substance (A) results in improved cosmetic characteristics of the agents according to the invention. Finally, the storage stability of the agents is not negatively influenced by these quantities.

[0043] As the second essential component b), the cosmetic agent according to the invention contains at least one second active substance (B), selected from the group of cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0044] In relation to the present invention, it is preferred if certain active substances (B) are used. Preferred embodiments of the present invention are therefore characterized in that the cosmetic agent according to the invention contains at least one second active substance (B), selected from the group of cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof. The use of these active substances (B) has proven to be especially advantageous in combination with the first active substance (A) in terms of deodorizing and/or antiperspirant performance. In particular, a synergistic increase in the deodorizing and/or antiperspirant performance is achieved. Moreover, through the use of these active substances (B), both the skin tolerance and the cosmetic characteristics of the agents according to the invention can be further increased. These compounds have the following chemical names and CAS numbers:

[0045] The deodorizing and/or antiperspirant effect can be further increased if the cosmetic agents contain more than one of the active substances (B) listed above. Preferred cosmetic agents are therefore characterized in that they contain at least two active substances (B), selected from the group of cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0046] Preferred cosmetic agents according to the invention are characterized in that they contain at least three active substances (B), selected from the group of cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0047] The cosmetic agents according to the invention preferably contain the second active substance (B) in certain quantity ranges. Preferred cosmetic agents according to the invention are therefore characterized in that they contain—with respect to their total weight—0.001 to 20 wt%, preferably 0.005 to 15 wt%, more preferably 0.01 to 10 wt%, particularly 0.05 to 2.0 wt%, of at least one second active substance (B). The use of such quantities of the at least one active substance (B) in combination with the first active substance (A) results in a synergistic increase in the deodorizing and/or antiperspirant performance. In this way, the quantity of active substances used can be reduced without negatively impacting the deodorizing and/or antiperspirant performance. The cosmetic agents according to the invention are therefore especially skin-friendly. In addition, the use of the abovementioned quantities of the second active substance (B) results in improved cosmetic characteristics of the agents according to the invention. Finally, the storage stability of the agents is not negatively influenced by these quantities.

[0048] Moreover, the cosmetic agents according to the invention can contain additional deodorant agents (C). However, the additional deodorant agent (C) is different from the first active substance (A) and the second active substance (B).

[0049] In the context of the present invention, it can be preferred if the cosmetic agent additionally contains a deodorant agent (C). Preferred agents are therefore characterized in that they additionally contain at least one deodorant agent (C) selected from the group of (i) active substances against exoesterases, particularly against arylsulfatase, lipase, beta-glucuronidase and cystathion-p-lyase; (ii) odor absorbers, particularly silicates, such as montmorillonite, kaolinite, illite, beidellite, nontronite, saponite, hectorite, bentonite, smectite and talcum, zeolites, zinc ricinoleate, cyclodextrins; (iii) deodorizing ion exchangers; (iv) germ-inhibiting agents; (v) prebiotically active components; as well as (vi) mixtures thereof.

[0050] Silicates act as odor absorbers which can simultaneously also advantageously support the rheological characteristics of the cosmetic agents according to the invention. The silicates that are especially advantageous according to the invention include, above all, layered silicates and, among those, particularly montmorillonite, kaolinite, illite, beidellite, nontronite, saponite, hectorite, bentonite, smectite and talcum. Examples of additional advantageous odor absorbers are zeolites, zinc ricinoleate, cyclodextrin, certain metal oxides, such as aluminum oxide, for example, as well as chlorophyll.

[0051] Moreover, the deodorant agent can be selected from the group of terpene alcohols such as farnesol, chlorophyllin copper complexes, carboxylic acid esters, particularly carboxylic acid monoesters of the mono-, di- and triglycerins (particularly glycerin monolaurate, diglycerin monocaprinate, diglycerin monolaurate, triglycerin monolaurate and triglycerin monomyristate) as well as plant extracts (e.g., green tea and components of lime blossom oil).

[0052] Additional preferred deodorant agents are selected from so-called prebiotically active components, which, according to the invention, are to be understood as such components which are only or at least predominantly the odor-producing germs of the skin microflora, but not the desired, that is, the non-odor-producing germs. Explicitly included here are the conifer extracts, particularly from the group of the Pinaceae, and plant extracts from the group of the Sapindaceae, Araliaceae, Lamiaceae and Saxifragaceae, particularly extracts from Picea spp., Paullinia sp., Panax sp., Lamium album or Ribes nigrum, as well as mixtures of these substances.

[0053] Other preferred deodorant agents are selected from the germ-inhibiting perfume oils and the Deosafe perfume oils that are available from the company Symrise, formerly Haarmann und Reimer.

[0054] The enzyme inhibitors include substances that inhibit the enzymes responsible for the decomposition of sweat, particularly arylsulfatase, β-glucuronidase, aminoacylase, the estercleaving lipases and lipoxigenase, for example zinc glycinate.

[0055] The at least one other deodorant agent (C) is preferably used in the cosmetic agents according to the invention in certain quantity ranges. It is therefore preferred in this context if they contain—with respect to their total weight—0.005 to 20 wt%, preferably 0.1 to 15 wt%, more preferably 0.1 to 13wt%, particularly 0.1 to 10 wt%, of at least one deodorant agent (C). If a mixture of deodorant agents is used, the abovementioned indicated quantities refer to the mixture of these active substances. In combination with active substances (A) and (B), the abovementioned quantities result in a greater increase in the deodorizing and/or antiperspirant performance as well as to a prolongation of this performance. Furthermore, these quantities result in improved cosmetic characteristics in the agents according to the invention. Finally, these quantities also do not have a negative impact on the storage stability of the cosmetic agents according to the invention.

[0056] In relation to the present invention, a provision can be made that, in addition to the previously mentioned additional deodorant agents, the cosmetic agents according to the invention contain other ingredients, selected from the group of (i) waxes; (ii) emulsifiers and/or surfactants; (iii) hydrogel formers; (iv) skin-cooling agents; (v) propellants; (vi) thickeners, and (vii) mixtures thereof.

[0057] The cosmetic agents according to the invention can also contain at least one wax. The term “wax” is understood in the context of the present invention as a substance that is kneadable or solid to brittle and hard at 20°C, have a coarse to fine crystalline structure, and whose color is translucent to opaque but not glassy. Moreover, these substances melt above 25°C without decomposing, are slightly fluid a little above the melting point (low viscosity), have a strongly temperature-dependent consistency and solubility and can be polished under slight pressure. It is therefore advantageous according to the invention if the cosmetic agent additionally contains at least one wax, the wax being selected from the group of (i) coconut fatty acid glycerin mono-, di-and triesters; (ii) Butyrospermum parkii (Shea butter); (iii) esters of saturated, monovalent C8.18 alcohols with saturated C12-is monocarboxylic acids; (iv) linear, primary C12-C24 alkanols; (v) esters from a saturated, monovalent C16-C60 alkanol and a saturated C8-C36 monocarboxylic acid, particularly cetyl behenate, stearyl behenate and C20-C40 alkyl stearate; (vi) glycerin triesters of saturated linear C12-C30 carboxylic acids, which can be hydroxylated, particularly hydrated palm oil, hydrated coconut oil, hydrated castor oil, glycerin tribehenate and glyceryltri-12-hydroxystearate; (vii) natural vegetable waxes, particularly candelilla wax, carnauba wax, Japan wax, sugar cane wax, ouricoury wax, cork wax, sunflower wax, fruit waxes; (viii) animal waxes, particularly beeswax, shellac wax and spermaceti; (ix) synthetic waxes, particularly montan ester waxes, hydrated jojoba waxes and sasol waxes, polyalkylene waxes and polyethylene glycol waxes, C20-C40 dialkyl esters of dimeric acids, C30-C50 alkyl beeswax, and alkyl and alkylaryl esters of dimerized fatty acids, paraffin waxes; as well as (x) mixtures thereof. The cosmetic agent preferably contains the additional at least one wax in a total quantity of 0.01 to 20 wt%, more preferably 3 to 20 wt%, even more preferably 5 to 18 wt%, particularly 6 to 15 wt% with respect to the total weight of the cosmetic agent.

[0058] Emulsifiers and surfactants that are preferably suitable according to the invention are selected from anionic, cationic, nonionic, amphoteric, particularly ampholytic and zwitterionic emulsifiers and surfactants. Surfactants are amphiphilic (bifunctional) compounds that consists of at least one hydrophobic and at least one hydrophilic moiety. The hydrophobic group is preferably a hydrocarbon chain with 8 to 28 carbon atoms, which can be saturated or unsaturated, linear or branched. Especially preferably, this C8-C28 alkyl chain is linear.

[0059] Anionic surfactants are understood as being surfactants with exclusively anionic charges; they contain carboxyl groups, sulfonic acid groups or sulfate groups, for example. Especially preferred anionic surfactants are alkyl sulfates, alkyl ether sulfates, acyl glutamates and C8.24 carboxylic acid as well as salts thereof, the so-called soaps.

[0060] Cationic surfactants are understood as being surfactants with exclusively cationic charges; they contain quaternary ammonium groups, for example. Cationic surfactants of the type of the quaternary ammonium compounds, the esterquats, and the amidoamines are preferred, for example. Preferred quaternary ammonium compounds are ammonium halogenides as well as the imidazole compounds known under the INCI designations quaternium-27 and quaternium-83. The quaternized protein hydrolysates represent other cationic surfactants that can be used according to the invention. Preferred esterquats are quaternized ester salts of fatty acids with triethanolamine, quaternized ester salts of fatty acids with diethanolalkylamines and quaternized ester salts of fatty acids with 1,2-dihydroxypropyldialkylamines.

[0061] The amphoteric surfactants are divided into ampholytic surfactants and zwitterionic surfactants. Ampholytic surfactants are understood as being such surface-active compounds which possess both acidic (for example, -COOH or -S03H groups) and basic hydrophilic groups (for example, amino groups) and therefore act acidically or basically depending on the condition. A person skilled in the art understands zwitterionic surfactants as being surfactants which carry both a negative and positive charge in the same molecule. Examples of preferred zwitterionic surfactants are the betaines, the N-alkyl-N,N-dimethylammonium glycinates, the N-acyl-aminopropyl-N,N-dimethylammonium glycinates, and the 2-alkyl-3-carboxymethyl-3-hydroxyethyl imidazolines, each with 8 to 24 carbon atoms in the alkyl group. Examples of preferred ampholytic surfactants are N-alkylglycine, N-alkylaminopropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropyl glycines, N-alkyl taurines, N-alkyl sarcosines, 2-alkylaminopropionic acids and alkylamino acetic acids, each with 8 to 24 carbon atoms in the alkyl group.

[0062] The cosmetic agents according to the invention, which are formulated as emulsions, particularly as oil-in-water emulsions, preferably contain at least one nonionic oil-in-water emulsifier with an HLB value of greater than 7 to 20. These are emulsifiers that are generally known to a person skilled in the art, such as those listed in Kirk-Othmer, “Encyclopedia of Chemical Technology,” 3rd edition, 1979, volume 8, pages 913-916. For ethoxylated products, the HLB value is calculated according to the formula HLB = (100 - L):5, where L is the proportion by weight of the lipophilic groups, that is, of the fatty alkyl or fatty acyl groups, in the ethylene oxide adducts, expressed in percent by weight. In this connection, it can be preferred according to the invention if a water-in-oil emulsifier with an HLB value of greater than 1.0 and less than or equal to 7.0 is still used. Nonionic oil-in-water emulsifiers and nonionic water-in-oil emulsifiers which are suitable in the context of the present invention are described, for example, in German published patent application DE 10 2006 004 957 A1.

[0063] To thicken the cosmetic agents according to the inventions, hydrogel-forming substances are preferably used which are selected from among cellulose ethers, above all hydroxyalkyl celluloses, particularly hydroxypropyl cellulose, hydroxypropylmethyl cellulose, hydroxyethyl cellulose, carboxymethyl cellulose, cetylhydroxyethyl cellulose, hydroxybutylmethyl cellulose, methylhydroxyethyl cellulose, as well as xanthan gum, sclerotium gum, succinoglycans, polygalactomannans, particularly guar gums and locust bean gum, particularly guar gum and locust bean gum themselves, and the nonionic hydroxyalkyl guar derivatives and locust bean gum derivatives, such as hydroxypropyl guar, carboxymethylhydroxypropyl guar, hydroxypropylmethyl guar, hydroxyethyl guar and carboxymethyl guar, as well as pectins, agar, carragheen (carrageenan), traganth, gum arabic, karaya gum, tara gum, gellan, gelatins, caseine, propylene glycol alginate, alginic acids and salts thereof, particularly sodium alginate, potassium alginate and calcium alginate, as well as polyvinyl pyrrolidones, polyvinyl alcohols, polyacrylamides. Especially preferred hydrogel formers are selected from among cellulose ethers, especially from hydroxyalkyl celluloses, particularly from hydroxypropyl celluloses, hydroxypropylmethyl celluloses, hydroxyethyl celluloses, carboxymethyl celluloses, cetylhydroxyethyl celluloses, hydroxybutylmethyl cellulosed and methylhydroxyethyl celluloses, as well as mixtures thereof. However, a lipophilic thickener can also be used. Lipophilic thickeners which are preferred according to the invention are selected from hydrophobized clay materials and pyrogenic silicic acids.

[0064] The cosmetic agents according to the invention can additionally contain at least one skincooling agent. Examples of skin-cooling agents which are suitable according to the invention are menthol, isopulegol and menthol derivatives, e.g., menthyl lactate, menthyl glycolate, menthyl ethyl oxamate, menthyl pyrrolidone carboxylic acid, menthyl methyl ether, menthoxy propanediol, menthone glycerin acetal (9-methyl-6-(1-methylethyl)-1,4-dioxaspiro (4.5)decan-2-methanol), monomenthyl succinate, 2-hydroxymethyl-3,5,5-trimethylcyclohexanol and 5-methyl-2-(1-methylethyl)cyclohexyl-N-ethyl oxamate. Preferred skin-cooling agents are menthol, isopulegol, menthyl lactate, menthoxy propanediol, menthylpyrrolidone carboxylic acid and 5-methyl-2-(1-methylethyl)cyclohexyl-N-ethyl oxamate, as well as mixtures of these substances, particularly mixtures of menthol and menthyl lactate, menthol, menthol glycolate and menthyl lactate, menthol and menthoxy propanediol or menthol and isopulegol.

[0065] Moreover, a provision can be made that the cosmetic agents according to the invention contain a propellant. In this case, they are packaged as propellant gas-driven aerosols. Preferred propellants (propellant gases) are propane, propene, n-butane, iso-butane, iso-butene, n-pentane, pentene, iso-pentane, iso-pentene, methane, ethane, dimethylether, nitrogen, air, oxygen, nitrous oxide, 1,1,1,3-tetrafluorethane, heptafluoro-n-propane, perfluorethane, monochlorodifluoromethane, 1,1-difluorethane, and tetrafluoropropene, both individually and in mixtures. Hydrophilic propellant gases such as carbon dioxide, for example, can be used advantageously in terms of the present invention if the proportion of hydrophilic gases is selected so as to be low and lipophilic propellant gas (e.g., propane/butane) is present in excess. Propane, n-butane, iso-butane and mixtures of these propellant gases are especially preferred. It was found that the use of n-butane as the sole propellant gas can be especially preferred according to the invention. The total quantity of propellants is 20 to 95 wt%, preferably 30 to 85 wt%, particularly 40 to 75 wt%, each with respect to the total weight of the cosmetic agent, consisting of the previously described components a) and b), as well as, optionally, the additional active substances and ingredients and the propellant.

[0066] The application of the cosmetic agent according to the invention can be achieved using different methods. According to a first embodiment, the cosmetic agent is packaged as a spray application. The spray application is performed using a spraying device containing a charge of the liquid, viscous/flowable, suspension-like or powdered antiperspirant cosmetic agent according to the invention in a container. The charge can be under the pressure of a propellant (pressurized gas cans, pressurized gas packaging, aerosol packaging), or a mechanically operated pump atomizer without propellant gas (pump sprays/squeezy bottle). The containers have a removal mechanism, preferably in the form of valves, which enable the removal of the contents as a mist, smoke, foam, powder, paste or liquid jet. Meriting consideration for the spraying devices are, above all, cylindrical vessels made of metal (aluminum, tinplate, capacity preferably no more than 1,000 ml_), protected or shatterproof glass or plastic (capacity preferably no more than 220 mL) or shattering glass or plastic (capacity preferably 50 to 400 mL). Creamy, gel-type, pasty and liquid agents from be packaged in pump, spray or squeeze dispensers, for example, particularly in multichamber pump, multichamber spray or multichamber squeeze dispensers. The packaging for the agents according to the invention can be opaque, but it can also be transparent or translucent.

[0067] According to a second embodiment, the cosmetic agent according to the invention can be packaged as a stick, soft solid, cream, roll-on, dibenzylidene alditol-based gel, or loose or compact powder. The formulation of the cosmetic agents according to the invention in a specific dosage form, such as a roll-on antiperspirant, antiperspirant stick or an antiperspirant gel, is preferably oriented around the requirements of the intended use. Depending on the intended use, the cosmetic agents according to the invention can therefore be present in solid, semisolid, liquid, dispersed, emulsified, suspended, gel-like, multiphase or powdered form. In terms of the present invention, the term “liquid” includes any type of solid dispersions in liquids. Moreover, in terms of the present invention, multiphase cosmetic agents according to the invention are understood as being agents having at least 2 different phases with a phase separation and in which the phases can be arranged horizontally, that is, over one another, or vertically, that is, next to one another.

[0068] They can be applied using a roll-on applicator, for example. Such rollers have a ball supported in a ball bed that can be moved through movement over a surface. The ball takes up some of the cosmetic agent according to the invention to be distributed and conveys it to the surface to be treated. As pointed out previously, the packaging for these agents can be opaque, transparent or translucent.

[0069] Moreover, it is also possible to apply the cosmetic agents according to the invention by means of a solid stick in the form of a solid emulsion.

[0070] According to a third embodiment, the cosmetic agent according to the invention can be contained on and/or in a disposable substrate, selected from the group of cloths, pads and wads. Wet wipes—that is, moist towelettes that are prefabricated for the used and preferably packaged individually, such as those which are well known from the area of glass cleaning or from the area of moist toilet papers—are especially preferred. Such wet wipes, which can advantageously also contain preservatives, are impregnated or loaded with a cosmetic agent according to the invention and preferably packaged individually. They can be used as deodorant wipes, for example, which is especially attractive for use while traveling. Preferred substrate materials are selected from porous flat cloths. They can be made of a fibrous or cellular, flexible material that has sufficient mechanical stability and simultaneously softness for use on the skin. These wipes include cloths made of woven and nonwoven (fleece), synthetic and natural fibers, felt, paper or foam, such as hydrophilic polyurethane foam. Deodorizing or antiperspirant substrates that are preferred according to the invention can be obtained by soaking or impregnation, or even by melting a cosmetic agent according to the invention onto a substrate.

[0071] Especially preferred embodiments AF1 to AF2619 of the cosmetic agents according to the invention are listed in the following table (all information is in wt% and refers to the total weight of the cosmetic agents). Here, W-A stands for the active substance (A); W-B stands for the active substance (B); t stands for triethyl citrate, eh stands for 3-[(2-Ethylhexyl)oxy]-1,2-propanediol; bh stands for 2-benzyl heptanol; p stands for phenoxyethanol, co stands for cocamidopropyl PG-dimonium chloride phosphate, hd stands for 1,2-hexanediol; od stands for 1,2-octanediol; dd stands for 1,2-decanediol; tp stands for tropolone; s stands for silver lactate; m stands for magnesium oxide; ach stands for aluminum chlorohydrate; azg stands for aluminum-zirconium tetrachlorohydrex glycine; c stands for cetylpyridinium chloride; be stands for benzalkonium chloride; bz stands for benzethonium chloride; zh stands for zinc hydroxide carbonate; zp stands for zinc phenolsulfonate; pc stands for polyglyceryl-2-caprate; so stands for sorbitan caprylate; oc stands for octenidine; ch stands for charnesolic acid, and w stands for tartaric acid. In the table, the signifier t+eh thus stands for a mixture of triethyl citrate and 3-[(2-ethylhexyl)oxy]-1,2-propanediol.

1) selected form the group of aqueous or aqueous-alcoholic or water-free carriers.

[0072] The abovementioned embodiments AF1 to AF2619 can additionally contain at least one deodorant agent (C), particularly from the group of the odor absorbers.

[0073] Through the synergistic effect of the combination of active substance (A) and active substance (B) in the abovementioned embodiments AF1 to AF2619, the quantity of active substances can be reduced without having a negative impact on the deodorizing and/or antiperspirant effect. Due to the reduced quantity of active substances, the abovementioned embodiments AF1 to AF2619 of the cosmetic agents according to the invention are low-irritant and low-sensitizing. Moreover, the use of this combination does not have a negative impact on the storage stability of the cosmetic agents according to the invention, so these agents have outstanding storage stability. Furthermore, the cosmetic characteristics can be improved through the combination of active substance (A) with active substance (B).

[0074] A second object of the present invention is a non-therapeutic cosmetic method for preventing and/or reducing body odor triggered by perspiration and or body perspiration per se in which a cosmetic agent according to the invention is applied to the skin, particularly to the skin of the armpits, and remains on the skin for at least 1 hour, preferably for at least 2 hours, more preferably for at least 4 hours, particularly for at least 6 hours.

[0075] The remarks made above in relation to the cosmetic agents according to the invention apply mutatis mutandis with respect to other preferred embodiments of the method according to the invention, particularly with respect to the cosmetic agents used.

[0076] Finally, another object of the present invention relates to the use of a cosmetic agent according to the invention to prevent and/or reduce the body odor triggered by perspiration and/or body perspiration per se.

[0077] The remarks made above in relation to the cosmetic agents according to the invention and method according to the invention apply mutatis mutandis with respect to other preferred embodiments of the use according to the invention, particularly with respect to the cosmetic agents used.

[0078] The following examples explain the present invention without limiting it:

Examples: 1. Formulations: [0080] Sprayable, translucent antiperspirant microemulsions (information in wt%, with respect to the propellant-free emulsion) u Mixture of active substance (A) and active

substance (B) is selected from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3) Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0081] Microemulsions 1.1 to 1.6 are each applied from a pressurized container (aerosol) using a suitable spraying system. Air, laughing gas, nitrogen, C02, and other compressible gases are used as propellants.

[0082] Antiperspirant emulsion (O/W) (information in wt%, with respect to the propellant-free emulsion) u Mixture of active substance (A) and active

[0083] Emulsions 2.1 to 2.3 are each applied from a pressurized container (aerosol) using a suitable spraying system. Air, laughing gas, nitrogen, C02, and other compressible gases are used as propellants.

[0084] Deodorant (information in wt%, with respect to the propellant-free deodorant)

υ Mixture of active substance (A) and active

[0085] Deodorant 3.1 to 3.3 is respectively applied from a pressurized container (aerosol) using a suitable spraying system. Air, laughing gas, nitrogen, C02, and other compressible gases are used as propellants.

[0086] Water-in-oil emulsions according to the invention (information in wt%, with respect to the total weight of the water-in-oil emulsion without propellant)

u Mixture of active substance (A) and active substance (B) is selected from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3) Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0087] Emulsions 4.1 to 4.3 are each applied from a pressurized container (aerosol) using a suitable spraying system. 15, 20, 25 or 30% of the respective emulsion is filled together with 85, 80, 75 or 70% of a suitable propellant gas, e.g., propane /butane /isobutane mixture (pressure 1.6 to 3.8 bar), into the aerosol container.

[0088] Emulsion according to the PIT method (information in wt%, with respect to the propellant-free emulsion):

Mixture of active substance (A) and active

[0089] Emulsions 5.1 to 5.3 are each applied from a pressurized container (aerosol) using a suitable spraying system. Air, laughing gas, nitrogen, C02, and other compressible gases are used as propellants.

[0090] Antiperspirant sticks according to the invention in the form of an oil-in-water emulsion (information in wt%)

[0100] Antiperspirant emulsion according to the invention (O/W) (information in wt%)

u Mixture of active substance (A) and active

[0101] The emulsions 7.1 to 7.3 were each filled into a roll-on applicator.

[0102] Water-free surfactant-containing antiperspirant sticks (information in wt%)

υ Mixture of active substance (A) and active substance (B) is selected from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3) Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0103] Water-free surfactant-containing antiperspirant sticks (information in wt%)

Mixture of active substance (A) and active substance (B) is selected from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3) Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0104] ‘Number-average particle size 3-20 pm [0105] Sprayable, translucent antiperspirant microemulsions (information in wt%)

[0106] Soap-containing deodorant sticks (information in wt%)

[0107] Deodorant in pump atomizer (information in wt%)

^ Mixture of active substance (A) and active

[0108] Antiperspirant roll-on (information in wt%)

[0109] Water-in-oil emulsions according to the invention (information in wt%)

Wipes (example nos. 14.1-14.4) [0110] For the embodiment according to the invention as an antiperspirant wipe, a single-layer substrate made of 100% viscose with a weight per unit area of 50 g/m2 with 75 g of exemplary emulsion 8.1 or 8.2 per square meter, or with 75 g of exemplary composition 12.1 or 12.2, cut into wipes of a suitable size, and packaged in sachets.

[0111] Antiperspirant cosmetic agents according to the invention in the form of a water-in-oil emulsion (information in wt%)

[0112] Antiperspirant cosmetic agents used according to the invention (information in wt%) u Mixture of active substance (A) and active

substance (B) is selected from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2- octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3) Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0113] Emulsion according to the PIT method (information in wt%):

Mixture of active substance (A) and active substance (B) is selected from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2- octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3) Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0114] Antiperspirant roll-on (information in wt%)

1J Mixture of active substance (A) and active substance (B) is selected from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2- octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3) Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0115] Antiperspirant cream (information in wt%)

υ Mixture of active substance (A) and active substance (B) is selected from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2- octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3) Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0116] Water-free deodorant sprays (information in wt%)

u Mixture of active substance (A) and active substance (B) is seeded from one of the abovementioned embodiments AF1 to AF2619. 2) Selected from among triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof. 3> Selected from among cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.

[0117] Suspension-type antiperspirant spray (information in wt%)

υ Mixture of active substance (A) and active

[0118] The following commercial products were used:

Claims

Claims 1) A cosmetic agent, containing, in a cosmetically acceptable carrier, a) at least one active substance (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, phosphates, alkanediols with 6 to 10 carbon atoms, tropolone, silver salts, alkaline earth oxides, aluminum salts, aluminum/zirconium salts, as well as mixtures thereof, and b) at least one second active substance (B), selected from the group of quaternary ammonium compounds, zinc salts, polyglycerol esters, sorbitan esters, octenidine, carnosic acid, tartaric acid, as well as mixtures thereof.
2) The cosmetic agent as set forth in claim 1, characterized in that the aluminum salt is selected from the group of (i) water-soluble astringent inorganic salts of aluminum, particularly aluminum ch loro hydrate, aluminum sesquichlorohydrate, aluminum dichlorohydrate, aluminum hydroxide, potassium aluminum sulfate, aluminum bromohydrate, aluminum chloride, aluminum sulfate; (ii) water-soluble astringent organic salts of aluminum, particularly aluminum chlorohydrex propylene glycol, aluminum chlorohydrex polyethylene glycol, aluminum propylene glycol complexes, aluminum sesquichlorohydrex propylene glycol, aluminum sesquichlorohydrex polyethylene glycol, aluminum propylene glycol dichlorohydrex, aluminum polyethylene glycol dichlorohydrex, aluminum undecylenoyl collagen amino acid, sodium aluminum lactate, sodium aluminum chlorohydroxy lactate, aluminum lipoamino acids, aluminum lactate, aluminum chlorohydroxy allantoinate, sodium aluminum chlorohydroxy lactate; and (iii) mixtures thereof.
3) The cosmetic agent as set forth in any one of claims 1 or 2, characterized in that the aluminum-zirconium salt is selected from the group of (i) water-soluble astringent inorganic aluminum-zirconium salts, particularly aluminum zirconium trichlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium pentachlorohydrate, aluminum zirconium octachlorohydrate; (ii) water-soluble astringent organic aluminum-zirconium salts, particularly aluminum zirconium propylene glycol complexes, aluminum zirconium trichlorohydrex glycine, aluminum zirconium tetrachlorohydrex glycine, aluminum zirconium pentachlorohydrex glycine, aluminum zirconium octachlorohydrex glycine; and (iii) mixtures thereof.
4) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it contains at least one first active substance (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG-dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum chlorohydrate, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof.
5) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it contains at least two active substances (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG- dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum chlorohydrate, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof.
6) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it contains at least three active substances (A), selected from the group of triethyl citrate, 3-[(2-ethylhexyl)oxy]-1,2-propanediol, 2-benzyl heptanol, phenoxyethanol, cocamidopropyl PG- dimonium chloride phosphate, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, tropolone, silver lactate, magnesium oxide, aluminum chlorohydrate, aluminum-zirconium tetrachlorohydrex glycine, as well as mixtures thereof.
7) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it contains—with respect to its total weight—0.0005 to 35 wt%, preferably 0.005 to 25 wt%, more preferably 0.01 to 10 wt%, particularly 0.05 to 8.0 wt%, of a first active substance (A).
8) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it contains at least one second active substance (B), selected from the group of cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.
9) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it contains at least two active substances (B), selected from the group of cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.
10) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it contains at least three active substances (B), selected from the group of cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, zinc hydroxide carbonate, zinc phenolsulfonate, polyglyceryl-2-caprate, sorbitan caprylate, octenidine, charnesolic acid, tartaric acid, as well as mixtures thereof.
11) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it contains—with respect to its total weight—0.001 to 20 wt%, preferably 0.005 to 15 wt%, more preferably 0.01 to 10 wt%, particularly 0.05 to 2.0 wt%, of at least one second active substance (B).
12) The cosmetic agent as set forth in any one of the preceding claims, characterized in that it additionally contains at least one deodorant agent (C) selected from the group of (i) active substances against exoesterases, particularly against arylsulfatase, lipase, beta-glucuronidase and cystathion-p-lyase; (ii) odor absorbers, particularly silicates, such as montmorillonite, kaolinite, illite, beidellite, nontronite, saponite, hectorite, bentonite, smectite and talcum, zeolites, zinc ricinoleate, cyclodextrins; (iii) deodorizing ion exchangers; (iv) germ-inhibiting agents; (v) prebiotically active components; as well as (vi) mixtures thereof.
13) The cosmetic agent as set forth in claim 12, characterized in that it contains—with respect to its total weight—0.005 to 20 wt%, preferably 0.1 to 15 wt%, more preferably 0.1 to 13 wt%, particularly 0.1 to 10 wt%, of at least one deodorant agent (C).
14) A non-therapeutic cosmetic method for preventing and/or reducing body odor triggered by perspiration and or body perspiration per se, in which a cosmetic agent as set forth in any one of claims 1 to 13 is applied to the skin, particularly to the skin of the armpits, and remains on the skin for at least 1 hour, preferably for at least 2 hours, more preferably for at least 4 hours, particularly for at least 6 hours.
15) A use of a cosmetic agent as set forth in any one of claims 1 to 13 for preventing and/or reducing body odor triggered by perspiration and/or body perspiration perse.