GB2499197A - Sunless tan remover comprising fulvic acid and water - Google Patents
Sunless tan remover comprising fulvic acid and water Download PDFInfo
- Publication number
- GB2499197A GB2499197A GB1202073.1A GB201202073A GB2499197A GB 2499197 A GB2499197 A GB 2499197A GB 201202073 A GB201202073 A GB 201202073A GB 2499197 A GB2499197 A GB 2499197A
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- tan
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- 239000002509 fulvic acid Substances 0.000 title abstract description 17
- PUKLDDOGISCFCP-JSQCKWNTSA-N 21-Deoxycortisone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(O)[C@@]1(C)CC2=O PUKLDDOGISCFCP-JSQCKWNTSA-N 0.000 title abstract description 13
- FCYKAQOGGFGCMD-UHFFFAOYSA-N Fulvic acid Natural products O1C2=CC(O)=C(O)C(C(O)=O)=C2C(=O)C2=C1CC(C)(O)OC2 FCYKAQOGGFGCMD-UHFFFAOYSA-N 0.000 title abstract description 13
- 229940095100 fulvic acid Drugs 0.000 title abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract description 3
- 239000010866 blackwater Substances 0.000 claims 1
- RXKJFZQQPQGTFL-UHFFFAOYSA-N dihydroxyacetone Chemical compound OCC(=O)CO RXKJFZQQPQGTFL-UHFFFAOYSA-N 0.000 description 26
- 229940120503 dihydroxyacetone Drugs 0.000 description 13
- 239000004021 humic acid Substances 0.000 description 11
- 210000003491 skin Anatomy 0.000 description 6
- 239000007921 spray Substances 0.000 description 6
- QJZYHAIUNVAGQP-UHFFFAOYSA-N 3-nitrobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid Chemical compound C1C2C=CC1C(C(=O)O)C2(C(O)=O)[N+]([O-])=O QJZYHAIUNVAGQP-UHFFFAOYSA-N 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- YQUVCSBJEUQKSH-UHFFFAOYSA-N 3,4-dihydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C(O)=C1 YQUVCSBJEUQKSH-UHFFFAOYSA-N 0.000 description 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 3
- 239000006210 lotion Substances 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000003415 peat Substances 0.000 description 3
- 235000013824 polyphenols Nutrition 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- UQPHVQVXLPRNCX-UHFFFAOYSA-N erythrulose Chemical compound OCC(O)C(=O)CO UQPHVQVXLPRNCX-UHFFFAOYSA-N 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 125000000524 functional group Chemical group 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 229910021645 metal ion Inorganic materials 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 150000002989 phenols Chemical class 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 150000004053 quinones Chemical class 0.000 description 2
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 description 2
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 description 1
- CGWXNFVBSPIYLA-UHFFFAOYSA-N 1,3-dihydropyrano[4,3-b]chromene-9-carboxylic acid Chemical compound C1OCC=C2OC3=C(C=C21)C(=CC=C3)C(=O)O CGWXNFVBSPIYLA-UHFFFAOYSA-N 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- 241000195940 Bryophyta Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 206010012442 Dermatitis contact Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000270322 Lepidosauria Species 0.000 description 1
- 230000010637 Metal Chelating Activity Effects 0.000 description 1
- 208000012641 Pigmentation disease Diseases 0.000 description 1
- 208000000453 Skin Neoplasms Diseases 0.000 description 1
- 206010047642 Vitiligo Diseases 0.000 description 1
- 230000021736 acetylation Effects 0.000 description 1
- 238000006640 acetylation reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 230000000536 complexating effect Effects 0.000 description 1
- 208000010247 contact dermatitis Diseases 0.000 description 1
- -1 cyclic polyphenols Chemical class 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 description 1
- 229940114124 ferulic acid Drugs 0.000 description 1
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 description 1
- 235000001785 ferulic acid Nutrition 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 150000002337 glycosamines Chemical class 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 230000011987 methylation Effects 0.000 description 1
- 238000007069 methylation reaction Methods 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000011929 mousse Nutrition 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- QHGUCRYDKWKLMG-UHFFFAOYSA-N octopamine Chemical compound NCC(O)C1=CC=C(O)C=C1 QHGUCRYDKWKLMG-UHFFFAOYSA-N 0.000 description 1
- 229960001576 octopamine Drugs 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- WKOLLVMJNQIZCI-UHFFFAOYSA-N vanillic acid Chemical compound COC1=CC(C(O)=O)=CC=C1O WKOLLVMJNQIZCI-UHFFFAOYSA-N 0.000 description 1
- TUUBOHWZSQXCSW-UHFFFAOYSA-N vanillic acid Natural products COC1=CC(O)=CC(C(O)=O)=C1 TUUBOHWZSQXCSW-UHFFFAOYSA-N 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
A formula consisting of fulvic acid and water for the removal of an artificial tan.
Description
Sunless Tan Remover
The use of Sunless Tanning Lotions (also known as artificial tanning, UV-free tanning, fake tanning) refers to the application of chemicals to the skin to produce an effect similar in appearance to a suntan The popularity of sunless tanning has risen since the 1960s after links were made by health authorities between exposure to the sun, and other sun tanning methods, such as sun beds or tanning beds and the incidence of skin cancer.
The most effective sunless tanning involves the use of lotions and sprays that contain dihydroxyacetone (DHA) as the active ingredient. DHA is not a dye, stain or paint, but causes a chemical reaction with the amino acids in the dead layer on the skin surface. This is similar to the Maillard reaction, a process well known to food chemists, that causes the browning that occurs during food manufacturing and storage. It does not involve skin pigmentation nor does it require exposure to ultraviolet light to initiate the color change. The effect is temporary and fades gradually over 3 to 10 days.
These products are available as gels, lotions, mousses, sprays and wipes, some of which also use erythrulose which works identically to DHA, but develops more slowly. Both DHA and erythrulose have been known to cause contact dermatitis. Professional spraytan applications are available from spas, salons and gymnasiums by both hand-held sprayers and in the form of sunless or UV-Free spray booths.The enclosed booth, which resembles an enclosed shower stall, sprays the tanning solution over the entire body. The U.S. Food and Drug Administration (FDA) states when using DHA-containing products as an all-over spray or mist in a commercial spray "tanning" booth, it may be difficult to avoid exposure in a manner for which DHA is not approved, including the area of the eyes, lips, or mucous membrane, or even internally. DHA is not approved by the FDA for inhalation. DHA has been approved for cosmetic use by the FDA. Because DHA does not use the skin's melanocytes to make the skin a tan color, it is recommended as a cosmetic disguising cover for vitiligo patients.
There are many versions of the sunless tan product for the consumer, most varying in concentrations of DHA. The general rule of thumb being that the higher the concentration of DHA, the longer the sunless tan lasts.
A particular characteristic of DHA based sunless tans is the deterioration in 'quality' of the tan as the lifecycle of the particular sunless tan nears its end. Sunless tans at this stage become unattractive, with scaley and lizard like characteristics. Despite numerous attempts there has been limited success in creating formula for the removal of sunless tan for 24+ hours after its application.
We first discovered that peat had reasonable success at removing sunless tan, but the consistency of the peat testing results was unsatisfactory. As a result we did further research and testing and discovered that the key component that was removing the sunless tan was a Humic Substance contained in peat called Fulvic Acid.
Our invention incorporates a formula consisting of Fulvic Acid mixed with Aqua. We found through extensive testing that the optimum ratio of Fulvic Acid to Water is 99.85% aqua to 0.15% concentrated Fulvic Acid. This ratio is not final and is solely reliant on the strength/concentration of Fulvic Acid source.
Our method for sunless tan removal is to apply our formula to the skin and to gently rub into the skin using cotton wool. This process removes the sunless tan.
Fulvic Acid Description
Humic and fulvic acids are multi-substituted polyaromatic heterocyclic macromolecules that incorporate protocatechuic acid, vanillic acid, vanillin, resorcinol, ferulic acid, benzoic acid, and other cyclic polyphenols resulting from the degradation of the lignin in plant cell walls. Humic and fulvic acids are rich in carboxyl, hydroxyl, and carbonyl groups as well as in phenols, quinones and semiquinones (Bruneton, 1995; Bravo, 1998; Yoshino, 1998). Within each macromolecule, aromatic groups are linked by amino acids, amino sugars, peptides and other aliphatic carbon chains (Buffle, 1977).
Humic substances are negatively-charged metal complexing ligands. There are a number of sites where metal ions may bind to aromatic and aliphatic carboxyl and phenolic hydroxyl groups within the humic acid complex, allowing humic substances to act as an ion exchanger, releasing metal ions of low atomic mass and chelating heavier metals (Aiken etal., 1985; Norden and Dabek-Zlotorynska, 1997; Wershaw, 1989; Gramss etal., 1999). These properties are abolished by ether methylation or acetylation of reactive sites (Frimmel and Christman, 1988).
The hypothetical structure provided by the petitioner for a humic acid is shown in Figure 1.
Chem/IUPAC Name / Description:
1H,3H-Pyrano[4,3-b][1]benzopyran-9-carboxylic acid, 4,10-dihydro-3,7,8-trihydroxy-3-methyl-10-oxo
HC=0
COCH COCH
Model structure of humic acid (Stevenson 1982)
I
C=0 NH-
I
(peptide)
Figure 1. Structural formula of a humic acid (taken from Stevenson, 1982).
Due to the variable molecular composition of humic acids, a wide range of dissociation constants exists for the metals that are chelated by humic acids.
Fulvic acids are generally known to be more oxygen-rich and carbon-poor than humic acids, reflected by relatively higher number of carboxyl and phenolic functional groups. Similar to its humic acid counterpart, fulvic acid contains many reactive functional groups, including carbonyls, hydroxyls, phenols, quinones and semiquinones. These reactive groups make fulvic acid a candidate for both metal chelating and antioxidant activity. The molecular weights of fulvic acids are thought to be lower than those of humic acids. Figure 2 presents an example of a molecular structure of fulvic acid as provided by the petitioner.
HOOC
HOOC
COOH OH
CH2—COOH
CHOH XCH2— XC0OH
0
Model structure of fulvic acid by Buffie
Figure 2. Structural formula of fulvic acid (taken from Buffie, 1977).
Claims (1)
- Claims1. A Sunless Tan (artificial tan, UV-free tan, fake tan) remover formula.•.'????.• INTELLECTUAL*.*. .V PROPERTY OFFICE4Application No: GB 1202073.1 Examiner: Mr Gareth ProtheroClaims searched: 1 Date of search: 2 May 2012Patents Act 1977: Search Report under Section 17Documents considered to be relevant:CategoryRelevant to claimsIdentity of document and passage or figure of particular relevanceX1CN102178630 A(XUEPING) See EPODOC and WPI abstracts.X1US2007/258917 A1(HANSENNE et al.) See whole document, for instance paragraphs [0050] and [0051],X1US2004/131575 Al(SERRUYS) See in particular paragraphs [0007] to [0012].X1W02007/102813 Al(ADVANTAGE) See for instance Example 26 at page 21.X1Blackwater drink, taken from the Internet at http://www.blackwaterdrink.com/products/blackwater-drink/ [date accessed 2 May 2012].Categories:XDocument indicating lack of novelty or inventiveADocument indicating technological background and/or statestepof the art.YDocument indicating lack of inventive step ifPDocument published on or after the declared priority date butcombined with one or more other documents ofbefore the filing date of this invention.same category.&Member of the same patent familyEPatent document published on or after, but with priority dateearlier than, the filing date of this application.Field of Search:Search of GB, EP, WO & US patent documents classified in the following areas of the UKC :Intellectual Property Office is an operating name of the Patent Office www.ipo.gov.uk•.'????.• INTELLECTUAL*.*. .V PROPERTY OFFICE5International Classification:SubclassSubgroupValid FromA61Q0019/0001/01/2006A61K0008/36201/01/2006Intellectual Property Office is an operating name of the Patent Office www.ipo.gov.uk
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1202073.1A GB2499197A (en) | 2012-02-07 | 2012-02-07 | Sunless tan remover comprising fulvic acid and water |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1202073.1A GB2499197A (en) | 2012-02-07 | 2012-02-07 | Sunless tan remover comprising fulvic acid and water |
Publications (2)
Publication Number | Publication Date |
---|---|
GB201202073D0 GB201202073D0 (en) | 2012-03-21 |
GB2499197A true GB2499197A (en) | 2013-08-14 |
Family
ID=45896721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1202073.1A Withdrawn GB2499197A (en) | 2012-02-07 | 2012-02-07 | Sunless tan remover comprising fulvic acid and water |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2499197A (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040131575A1 (en) * | 2002-12-20 | 2004-07-08 | Kari Serruys | Stain removing composition |
WO2007102813A1 (en) * | 2006-03-07 | 2007-09-13 | Advantage Marketing, Inc. | Compositions and methods for human use containing fulvic acid |
US20070258917A1 (en) * | 2006-05-03 | 2007-11-08 | L'oreal | Process for removing or lightening stains caused by skin coloring agents |
CN102178630A (en) * | 2011-04-26 | 2011-09-14 | 李雪萍 | Cosmetic application method of biological acid and cosmetic preparation of biological acid |
-
2012
- 2012-02-07 GB GB1202073.1A patent/GB2499197A/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040131575A1 (en) * | 2002-12-20 | 2004-07-08 | Kari Serruys | Stain removing composition |
WO2007102813A1 (en) * | 2006-03-07 | 2007-09-13 | Advantage Marketing, Inc. | Compositions and methods for human use containing fulvic acid |
US20070258917A1 (en) * | 2006-05-03 | 2007-11-08 | L'oreal | Process for removing or lightening stains caused by skin coloring agents |
CN102178630A (en) * | 2011-04-26 | 2011-09-14 | 李雪萍 | Cosmetic application method of biological acid and cosmetic preparation of biological acid |
Non-Patent Citations (1)
Title |
---|
Blackwater drink, taken from the Internet at http://www.blackwaterdrink.com/products/blackwater-drink/ [date accessed 2 May 2012]. * |
Also Published As
Publication number | Publication date |
---|---|
GB201202073D0 (en) | 2012-03-21 |
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Legal Events
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---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |