GB2382921B - Mass spectrometer and methods of mass spectrometry - Google Patents

Mass spectrometer and methods of mass spectrometry

Info

Publication number
GB2382921B
GB2382921B GB0228092A GB0228092A GB2382921B GB 2382921 B GB2382921 B GB 2382921B GB 0228092 A GB0228092 A GB 0228092A GB 0228092 A GB0228092 A GB 0228092A GB 2382921 B GB2382921 B GB 2382921B
Authority
GB
United Kingdom
Prior art keywords
analyser
sensitivity mode
mass
methods
ions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB0228092A
Other versions
GB0228092D0 (en
GB2382921A (en
Inventor
Martin Green
Michael Jackson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0029040.3A external-priority patent/GB0029040D0/en
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of GB0228092D0 publication Critical patent/GB0228092D0/en
Publication of GB2382921A publication Critical patent/GB2382921A/en
Application granted granted Critical
Publication of GB2382921B publication Critical patent/GB2382921B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

A way of increasing the dynamic range of a mass spectrometer which incorporates a time to digital converter such as commonly used with a time of flight mass analyser 9 is disclosed. A z-lens 4 upstream of the analyser 9 can be switched between a high sensitivity mode wherein a beam of ions 2 passing therethrough is substantially focused on to the entrance slit 10 of the analyser 9, and a low sensitivity mode wherein the beam of ions 2 is defocused so that the diameter of the beam substantially exceeds that of the entrance slit 10 of the analyser 9. Obtaining data in the low sensitivity mode in combination with obtaining data in the high sensitivity mode enable an order of magnitude increase in the dynamic range to be obtained. <IMAGE>
GB0228092A 2000-11-29 2001-04-02 Mass spectrometer and methods of mass spectrometry Expired - Lifetime GB2382921B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0029040.3A GB0029040D0 (en) 2000-11-29 2000-11-29 Orthogonal time of flight mass spectrometer
GB0108187A GB2369721B (en) 2000-11-29 2001-04-02 Mass spectrometer and method of mass spectrometry

Publications (3)

Publication Number Publication Date
GB0228092D0 GB0228092D0 (en) 2003-01-08
GB2382921A GB2382921A (en) 2003-06-11
GB2382921B true GB2382921B (en) 2003-10-29

Family

ID=26245351

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0228092A Expired - Lifetime GB2382921B (en) 2000-11-29 2001-04-02 Mass spectrometer and methods of mass spectrometry

Country Status (5)

Country Link
EP (1) EP1215711B1 (en)
AT (2) ATE368937T1 (en)
CA (1) CA2343582C (en)
DE (2) DE60126048T2 (en)
GB (1) GB2382921B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0029040D0 (en) * 2000-11-29 2001-01-10 Micromass Ltd Orthogonal time of flight mass spectrometer
US7038197B2 (en) 2001-04-03 2006-05-02 Micromass Limited Mass spectrometer and method of mass spectrometry
US7095015B2 (en) 2001-10-22 2006-08-22 Micromass Uk Limited Mass spectrometer
GB2388704B (en) * 2002-05-17 2004-08-11 * Micromass Limited Mass spectrometer and method of mass spectrometry
EP1365437B1 (en) * 2002-05-17 2014-08-20 Micromass UK Limited Mass spectrometer and method of mass spectrometry
US20050080571A1 (en) * 2003-10-10 2005-04-14 Klee Matthew S. Mass spectrometry performance enhancement
GB2428876B (en) * 2004-04-05 2008-10-01 Micromass Ltd Mass spectrometer
EP1738396B1 (en) * 2004-04-05 2018-10-31 Micromass UK Limited Mass spectrometer
JP2006032109A (en) * 2004-07-15 2006-02-02 Jeol Ltd Orthogonal acceleration time-of-flight mass spectroscope
GB2467548B (en) 2009-02-04 2013-02-27 Nu Instr Ltd Detection arrangements in mass spectrometers
GB0918629D0 (en) 2009-10-23 2009-12-09 Thermo Fisher Scient Bremen Detection apparatus for detecting charged particles, methods for detecting charged particles and mass spectometer
GB0918630D0 (en) 2009-10-23 2009-12-09 Thermo Fisher Scient Bremen Detection apparatus for detecting charged particles, methods for detecting charged particles and mass spectrometer
GB2486484B (en) 2010-12-17 2013-02-20 Thermo Fisher Scient Bremen Ion detection system and method
CN109767971A (en) * 2019-03-08 2019-05-17 昆山禾信质谱技术有限公司 Two-dimensional beam deflection device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747800A (en) * 1995-12-13 1998-05-05 Hitachi, Ltd. Three-dimensional quadrupole mass spectrometer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300774A (en) * 1991-04-25 1994-04-05 Applied Biosystems, Inc. Time-of-flight mass spectrometer with an aperture enabling tradeoff of transmission efficiency and resolution

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747800A (en) * 1995-12-13 1998-05-05 Hitachi, Ltd. Three-dimensional quadrupole mass spectrometer

Also Published As

Publication number Publication date
DE60126048T2 (en) 2007-06-06
ATE352096T1 (en) 2007-02-15
DE60129751T2 (en) 2008-04-30
EP1215711A2 (en) 2002-06-19
CA2343582A1 (en) 2002-05-29
DE60126048D1 (en) 2007-03-08
GB0228092D0 (en) 2003-01-08
EP1215711B1 (en) 2007-01-17
DE60129751D1 (en) 2007-09-13
CA2343582C (en) 2010-06-15
GB2382921A (en) 2003-06-11
EP1215711A3 (en) 2004-04-28
ATE368937T1 (en) 2007-08-15

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Expiry date: 20210401