GB2377634A - Preparation of spirillicide - Google Patents

Preparation of spirillicide Download PDF

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Publication number
GB2377634A
GB2377634A GB0117474A GB0117474A GB2377634A GB 2377634 A GB2377634 A GB 2377634A GB 0117474 A GB0117474 A GB 0117474A GB 0117474 A GB0117474 A GB 0117474A GB 2377634 A GB2377634 A GB 2377634A
Authority
GB
United Kingdom
Prior art keywords
particles
pills
pork
spirillicide
fried
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0117474A
Other versions
GB0117474D0 (en
GB2377634B (en
Inventor
Shian Shyang Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB0117474A priority Critical patent/GB2377634B/en
Publication of GB0117474D0 publication Critical patent/GB0117474D0/en
Publication of GB2377634A publication Critical patent/GB2377634A/en
Application granted granted Critical
Publication of GB2377634B publication Critical patent/GB2377634B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1664Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats

Abstract

A method for making spirillicide includes mixing a chloride hydrargyrum (Hg<SB>2</SB>Cl<SB>2</SB>) material and a gypsum material and pork into particles, and the particles are then fried into pills. The chloride hydrargyrum (Hg<SB>2</SB>Cl<SB>2</SB>) material and the gypsum material are preferably ground into a mixed powder material before mixing with the pork, and may be fried with the sesame oil, or the peanut oil, or the soybean oil. The fried particles may be cooled into the room temperature under the room temperature, and may be refrigerated into the pills.

Description

<Desc/Clms Page number 1>
METHOD FOR MAKING SPIRILLICIDE The invention relates to a method for making spirillicide.
Various kinds of typical diseases, such as the syphilis, are constituted or formed by spirilla which may decompose the human tissue, such as the skin of people, and which may infect the other people. Various kinds of medicines have been developed as spirillicide.
However, actually, the so-called spirillicide may be used for restraining the growing of the spirilla only and may not be used for actually killing the spirilla.
It is accordingly an object of the present invention to provide a method for making spirillicide that may be used for killing spirilla.
SUMMARY OF THE INVENTION According to the present invention there is provided a method for making spirillicide, the method comprising:
Cl,)) material a) mixing a chloride hydrargyrum (HgCl) material and a gypsum material and pork into particles, and b) frying the particles into pills.
A grinding process is further provided for
grinding the chloride hydrargyrum (Hg2C12) material and en M2- the gypsum material into a mixed powder material.
The mixed powder material are then mixed with the pork and formed into the particles.
The frying process includes frying the particles C-1-e
<Desc/Clms Page number 2>
with sesame oil, or with the peanut oil, or with the soybean oil.
It is preferable that each of the pills includes 90% of pork, about 0.09g ; 5% of sesame oil, about 0. 005g ; 3.5% of chloride hydrargyrum material, about 0. 0035g ; and 1.5% of gypsum material, about 0. 0015g ; such that each of the pills preferably includes a weight of about O. lg.
A cooling process is further provided for cooling the fried particles, and a refrigerating process may further be provided for refrigerating the fried particles into the pills.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a block diagram showing a method for making spirillicide; FIG. 2 is a chart illustrating the effect derived from different oils used; and FIG. 3 is a chart illustrating the spirilla killing effect of the spirillicide made by the method of the invention.
DESCRIPTION OF THE PREFERRED EMBODIMENT As shown in FIG. 1, a method for making spirillicide comprises preparing (1) a chloride hydrargyrum (HgCI) powder, and preparing (2) a gypsum material, and grinding (3) the chloride hydrargyrum
(HgCl) powder and the gypsum material into mixed 112 2) powder material. and mixing (4) the mixed powder
<Desc/Clms Page number 3>
material with pork, particularly the raw pork, and formed into pills or particles manually or by machines.
The particles are then fried (5) in an oil, such as, as shown in FIG. 2, the sesame oil, the peanut oil, the soybean oil, or the like, until the pork is well cooked. The fried particles may include a slightly fried yellow color. The fried particles are then cooled (6) under such as the room temperature, for about one hour, until the fried particles have been cooled to the room temperature. The cooled particles are then refrigerated (7) so as to form the final particles or the pills (8).
It is preferable that the pills (8) each weights about O. lg. One example of the proportion of the materials included in each of the particles or pills 8 is as follows: (1) 90% of pork, about 0. 09g ; (2) 5% of sesame oil, about 0.005g ; (3) 3.5% of chloride hydrargyrum (HgCl), about 0. 0035g ; and (4) 1.5% of gypsum, about 0. 0015g.
The total of the four materials of the above example will then be 100%, about O. lg. for each of the pills 8.
Referring next to FIG. 3, when a patient consumes five (5) pills 8 a day, the spirilla may be completely killed in two and a half (2. 5) years. As shown in FIG.
<Desc/Clms Page number 4>
2, the sesame oil includes a great proportion of sesame phenols which may promote or increase the killing effect against the spirilla which may be discharged out of the patient via the urine, the droppings, or the like. Accordingly, the sesame oil may include a better killing effect against the spirilla than the other oils (FIG. 2).
The chloride hydrargyrum (Hg2C12) powder may be become a solvable hydrargyrum material which may stimulate the stomach of the patient, and may cause or promote the wriggling of the stomach and may promote the internal secretion, after the spirilla have been killed by the spirillicide. The grease or the oil of the pork may protect the stomach for preventing the stomach from being damaged or over-stimulated by the solvable hydrargyrum material of the chloride hydrargyrum (HgCl) powder. The gypsum may be used for heat dissipating purposes for the patients for decreasing or for removing the heat generated in the patients.

Claims (9)

  1. CLAIMS :- 1. A method for making spirillicide, said method c : l comprising : mixing a chloride hydrargyrum material and a 0 gypsum material and pork into particles, and frying said particles into pills.
  2. 2. The method as claimed in claim 1 further comprising grinding said chloride hydrargyrum material and said gypsum material into a mixed powder material.
  3. 3. The method as claimed in claim 2 further comprising mixing said mixed powder material with said pork and forming into said particles.
  4. 4. The method as claimed in claim 1, wherein said frying process includes frying said particles with sesame oil.
  5. 5. The method as claimed in claim 4, wherein the pills each includes 90% of pork, 5% of sesame oil. 3.5% of chloride hydrargyrum material, and 1.5% of gypsum material.
  6. 6. The method as claimed in claim 1 further comprising cooling said fried particles.
  7. 7. The method as claimed in claim 1 further comprising refrigerating said fried particles into said pills.
  8. 8. The method substantially as herein described with reference to the accompanying drawings.
  9. 9. A spirillicide made by the method claimed in any one of the preceding claims.
    9. A spirillicide made by the method claimed in any one of the preceding claims.
    <Desc/Clms Page number 6>
    Claims :-
    1. A method of making a spirillicide which comprises mixing mercurous chloride, gypsum and pork so as to form pills or particles, and frying the formed pills or particles.
    2. A method as claimed in Claim 1, which includes grinding together the mercurous chloride and the gypsum to produce a mixed powder material.
    3. A method as claimed in Claim 2, which includes mixing the mixed powder material and the pork and then forming the pills or particles from the mixture thus produced.
    4. A method as claimed in any one of the preceding claims, in which the formed pills or particles are fried in sesame oil.
    5. A method as claimed in Claim 4, in which the pills or particles include 90% by weight pork, 5% by weight sesame oil, 3.5% by weight mercurous chloride, and 1. 5% by weight gypsum.
    6. A method as claimed in any one of the preceding claims, which includes cooling the fried pills or particles.
    7. A method as claimed in Claim 6, which includes refrigerating the cooled, fried pills or particles.
    <Desc/Clms Page number 7>
    8. A method of making a spirillicide substantially as hereinbefore described with reference to the accompanying drawings.
GB0117474A 2001-07-18 2001-07-18 Method of making a spirillicide Expired - Fee Related GB2377634B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0117474A GB2377634B (en) 2001-07-18 2001-07-18 Method of making a spirillicide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0117474A GB2377634B (en) 2001-07-18 2001-07-18 Method of making a spirillicide

Publications (3)

Publication Number Publication Date
GB0117474D0 GB0117474D0 (en) 2001-09-12
GB2377634A true GB2377634A (en) 2003-01-22
GB2377634B GB2377634B (en) 2003-06-25

Family

ID=9918703

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0117474A Expired - Fee Related GB2377634B (en) 2001-07-18 2001-07-18 Method of making a spirillicide

Country Status (1)

Country Link
GB (1) GB2377634B (en)

Also Published As

Publication number Publication date
GB0117474D0 (en) 2001-09-12
GB2377634B (en) 2003-06-25

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Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20050718