GB2348808B - Methods and compositions for desensitisation - Google Patents

Methods and compositions for desensitisation

Info

Publication number
GB2348808B
GB2348808B GB0016438A GB0016438A GB2348808B GB 2348808 B GB2348808 B GB 2348808B GB 0016438 A GB0016438 A GB 0016438A GB 0016438 A GB0016438 A GB 0016438A GB 2348808 B GB2348808 B GB 2348808B
Authority
GB
United Kingdom
Prior art keywords
desensitisation
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0016438A
Other languages
English (en)
Other versions
GB0016438D0 (en
GB2348808A (en
Inventor
Mark Larche
Anthony Barrington Kay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Niox Healthcare Ltd
Original Assignee
Circassia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9800445.0A external-priority patent/GB9800445D0/en
Priority claimed from GBGB9820474.6A external-priority patent/GB9820474D0/en
Application filed by Circassia Ltd filed Critical Circassia Ltd
Publication of GB0016438D0 publication Critical patent/GB0016438D0/en
Publication of GB2348808A publication Critical patent/GB2348808A/en
Application granted granted Critical
Publication of GB2348808B publication Critical patent/GB2348808B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0003—Invertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB0016438A 1998-01-09 1999-01-11 Methods and compositions for desensitisation Expired - Fee Related GB2348808B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9800445.0A GB9800445D0 (en) 1998-01-09 1998-01-09 Method for desensitisation
GBGB9820474.6A GB9820474D0 (en) 1998-09-21 1998-09-21 Method for desensitisation
PCT/GB1999/000080 WO1999034826A1 (en) 1998-01-09 1999-01-11 Methods and compositions for desensitisation

Publications (3)

Publication Number Publication Date
GB0016438D0 GB0016438D0 (en) 2000-08-23
GB2348808A GB2348808A (en) 2000-10-18
GB2348808B true GB2348808B (en) 2003-03-19

Family

ID=26312916

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0016438A Expired - Fee Related GB2348808B (en) 1998-01-09 1999-01-11 Methods and compositions for desensitisation

Country Status (7)

Country Link
US (1) US20040265342A1 (cg-RX-API-DMAC7.html)
EP (1) EP1044019A1 (cg-RX-API-DMAC7.html)
JP (1) JP2002500198A (cg-RX-API-DMAC7.html)
AU (1) AU2064899A (cg-RX-API-DMAC7.html)
CA (1) CA2317724A1 (cg-RX-API-DMAC7.html)
GB (1) GB2348808B (cg-RX-API-DMAC7.html)
WO (1) WO1999034826A1 (cg-RX-API-DMAC7.html)

Families Citing this family (34)

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DE69940805D1 (de) 1998-01-31 2009-06-10 Sinai School Medicine Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie
AUPQ884500A0 (en) * 2000-07-18 2000-08-10 National University Of Singapore, The Novel therapeutic molecules and uses therefor - III
US6572859B1 (en) 1999-10-29 2003-06-03 Pharmacia Diagnostics Ab Non-anaphylactic forms of grass pollen Phl p 6 allergen and their use
EP2258852A1 (en) * 2000-04-28 2010-12-08 Novozymes A/S Lipolytic enzyme variant
IT1318690B1 (it) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti dell'allergene maggiore par j 2 di parietaria judaica.
FR2824326B1 (fr) * 2001-05-04 2004-03-19 Commissariat Energie Atomique Melange de peptides issus des proteines e6 et/ou e7 de papillomavirus et leurs applications
AUPR779201A0 (en) * 2001-09-20 2001-10-11 University Of Melbourne, The Immunotherapeutic and immunoprophylactic reagents
DE60229979D1 (cg-RX-API-DMAC7.html) * 2001-12-05 2009-01-02 Circassia Ltd
SE0200946D0 (sv) * 2002-03-27 2002-03-27 Pharmacia Diagnostics Ab Novel Allergen
CN100509844C (zh) * 2002-08-19 2009-07-08 默克专利股份公司 来自梯牧草的主要过敏原Phl p1的变异体
EP1403280B1 (en) * 2002-09-27 2005-08-31 BIOMAY Produktions- und Handels- Aktiengesellschaft Hypoallergenic allergy vaccines based on the timothy grass pollen allergen Phl p 7
US7923209B2 (en) 2003-03-14 2011-04-12 Anergis, S.A. Allergen peptide fragments and use thereof
EP2001515A2 (en) * 2006-03-30 2008-12-17 The Regents of the University of California Ige directed dna vaccination
EP1958645A1 (en) * 2007-02-13 2008-08-20 Biomay AG Peptides derived from the major allergen of ragweed (Ambrosia artemisiifolia) and uses thereof
AU2013202871B2 (en) * 2007-06-01 2015-10-22 Circassia Limited Vaccine peptide combinations against cat allergy
GB0710529D0 (en) * 2007-06-01 2007-07-11 Circassia Ltd Vaccine
WO2009022155A2 (en) 2007-08-15 2009-02-19 Circassia Limited Peptide with reduced dimer formation
US20110124683A1 (en) * 2007-11-13 2011-05-26 Oxagen Limited Use of CRTH2 Antagonist Compounds
DK2153841T4 (en) 2008-08-15 2016-02-15 Circassia Ltd Vaccine comprising Amb a 1 peptides for use in the treatment of ambrosieallergi
US8821887B2 (en) 2008-08-15 2014-09-02 Circassia Limited T-cell antigen peptide from allergen for stimulation of IL-10 production
AU2015227499B2 (en) * 2008-11-28 2017-06-22 Circassia Limited Compositions with reduced dimer formation
GB0821806D0 (en) * 2008-11-28 2009-01-07 Circassia Ltd Compositions with reduced dimer formation
BRPI1008802A2 (pt) 2009-02-05 2016-03-08 Circassia Ltd composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição
WO2011085783A1 (de) * 2010-01-14 2011-07-21 Merck Patent Gmbh VARIANTEN DER GRUPPE 5-ALLERGENE DER SÜßGRÄSER MIT REDUZIERTER ALLERGENITÄT DURCH MUTAGENESE VON PROLINRESTEN
GB201002559D0 (en) 2010-02-15 2010-03-31 Circassia Ltd Birch peptides for vaccine
CN118078979A (zh) 2011-04-29 2024-05-28 西莱克塔生物科技公司 用于降低针对治疗性蛋白的免疫应答的致耐受性合成纳米载体
US11421006B2 (en) 2012-05-03 2022-08-23 La Jolla Institute For Allergy And Immunology T cell epitopes from Cockroach and methods of making and using same
DK2914286T3 (da) 2012-10-30 2021-11-08 Aravax Pty Ltd Hidtil ukendte immunterapeutiske molekyler og anvendelser deraf
US10434088B2 (en) 2013-05-03 2019-10-08 Selecta Biosciences, Inc. Methods related to administering immunosuppressants and therapeutic macromolecules at a reduced pharmacodynamically effective dose
JP7007534B2 (ja) 2013-09-25 2022-01-24 アラヴァックス ピーティーワイ リミテッド 新規免疫療法組成物およびその使用
WO2016037165A1 (en) 2014-09-07 2016-03-10 Selecta Biosciences, Inc. Methods and compositions for attenuating exon skipping anti-viral transfer vector immune responses
CN108265057B (zh) * 2016-12-31 2019-10-18 江苏众红生物工程创药研究院有限公司 一种重组户尘螨2类变应原蛋白及其制备方法和应用
CN108265059B (zh) * 2016-12-31 2021-01-05 江苏众红生物工程创药研究院有限公司 一种重组粉尘螨2类变应原蛋白及其制备方法与应用
CA3055936A1 (en) 2017-03-11 2018-09-20 Selecta Biosciences, Inc. Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992011859A1 (en) * 1991-01-08 1992-07-23 Immulogic Pharmaceutical Corporation Peptide-mediated hyposensitization of the human t cell response to dermatophagoides spp. (house dust mite)
WO1995026980A2 (en) * 1994-04-01 1995-10-12 Immulogic Pharmaceutical Corporation Haptenated peptides and uses thereof
US5547669A (en) * 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
WO1997032600A1 (fr) * 1996-03-10 1997-09-12 Meiji Milk Products Co., Ltd. Agent immunotherapeutique a base peptidique pour le traitement des allergies
WO1997033910A1 (en) * 1996-03-11 1997-09-18 The Rockefeller University Immunomodulatory peptides of vespid antigen 5

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4163778A (en) * 1978-05-04 1979-08-07 The Foundation for the Study of Asthma and Related Diseases Asthma immunotherapy
US4338297A (en) * 1980-02-19 1982-07-06 Michael Jacob G Polypeptide active pollen immunosuppressant fraction
US6180368B1 (en) * 1988-03-23 2001-01-30 University Of Melbourne Ryegrass pollen allergen
US6019972A (en) * 1989-11-03 2000-02-01 Immulogic Pharmaceutical Corporation Peptides of human T cell reactive feline protein (TRFP)
FR2715538B1 (fr) * 1994-02-01 1996-04-26 Roquette Freres Composition de chewing-gum présentant une qualité organoleptique améliorée et procédé permettant de préparer un tel chewing-gum.

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547669A (en) * 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
WO1992011859A1 (en) * 1991-01-08 1992-07-23 Immulogic Pharmaceutical Corporation Peptide-mediated hyposensitization of the human t cell response to dermatophagoides spp. (house dust mite)
WO1995026980A2 (en) * 1994-04-01 1995-10-12 Immulogic Pharmaceutical Corporation Haptenated peptides and uses thereof
WO1997032600A1 (fr) * 1996-03-10 1997-09-12 Meiji Milk Products Co., Ltd. Agent immunotherapeutique a base peptidique pour le traitement des allergies
EP0923940A1 (en) * 1996-03-10 1999-06-23 Meiji Milk Products Company Limited Peptide-base immunotherapeutic agent for allergic diseases
WO1997033910A1 (en) * 1996-03-11 1997-09-18 The Rockefeller University Immunomodulatory peptides of vespid antigen 5

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Am. J. of Respiratory & Critical Care Med. Vol 154(6), (1996), Norman et al, "Treatment of cat allergy with T-Cell...", pgs 1623-1628 *
Journal of Immunology Vol 152, (1994), Van Neerven et al, "Characterisation of cat dander-specific...", pgs 4203-4210 *

Also Published As

Publication number Publication date
EP1044019A1 (en) 2000-10-18
AU2064899A (en) 1999-07-26
GB0016438D0 (en) 2000-08-23
JP2002500198A (ja) 2002-01-08
WO1999034826A1 (en) 1999-07-15
GB2348808A (en) 2000-10-18
CA2317724A1 (en) 1999-07-15
US20040265342A1 (en) 2004-12-30

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20170111