GB2209338A - Antiviral agents - Google Patents

Antiviral agents

Info

Publication number
GB2209338A
GB2209338A GB8821380A GB8821380A GB2209338A GB 2209338 A GB2209338 A GB 2209338A GB 8821380 A GB8821380 A GB 8821380A GB 8821380 A GB8821380 A GB 8821380A GB 2209338 A GB2209338 A GB 2209338A
Authority
GB
United Kingdom
Prior art keywords
compounds
formula
phosphonate
salts
azidomethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB8821380A
Other languages
English (en)
Other versions
GB8821380D0 (en
Inventor
Elmer Jospeh Reist
Priscilla A Sturm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SRI International Inc
Original Assignee
SRI International Inc
Stanford Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SRI International Inc, Stanford Research Institute filed Critical SRI International Inc
Publication of GB8821380D0 publication Critical patent/GB8821380D0/en
Publication of GB2209338A publication Critical patent/GB2209338A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8821380A 1987-01-20 1988-09-12 Antiviral agents Pending GB2209338A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US547187A 1987-01-20 1987-01-20
PCT/US1987/003446 WO1988005438A1 (en) 1987-01-20 1987-12-23 Antiviral agents

Publications (2)

Publication Number Publication Date
GB8821380D0 GB8821380D0 (en) 1988-11-02
GB2209338A true GB2209338A (en) 1989-05-10

Family

ID=21716038

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8821380A Pending GB2209338A (en) 1987-01-20 1988-09-12 Antiviral agents

Country Status (7)

Country Link
EP (1) EP0309491A1 (enExample)
JP (1) JPH01501864A (enExample)
DE (1) DE3790883T1 (enExample)
GB (1) GB2209338A (enExample)
NL (1) NL8720745A (enExample)
SE (1) SE8803309D0 (enExample)
WO (1) WO1988005438A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0335770B1 (en) * 1988-04-01 1997-01-15 Merrell Pharmaceuticals Inc. Novel fluorophosphonate nucleotide derivatives
US5208221A (en) * 1990-11-29 1993-05-04 Bristol-Myers Squibb Company Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives
AU2641192A (en) * 1991-09-24 1993-04-27 Wellcome Foundation Limited, The Therapeutic nucleosides
US5532225A (en) * 1992-07-31 1996-07-02 Sri International Acyclic purine phosphonate nucleotide analogs as antiviral agents, and related synthetic methods
JPH09506333A (ja) * 1993-09-17 1997-06-24 ギリアード サイエンシーズ，インコーポレイテッド 治療化合物の投薬方法
US5798340A (en) 1993-09-17 1998-08-25 Gilead Sciences, Inc. Nucleotide analogs
US5717095A (en) * 1995-12-29 1998-02-10 Gilead Sciences, Inc. Nucleotide analogs
US5877166A (en) * 1996-04-29 1999-03-02 Sri International Enantiomerically pure 2-aminopurine phosphonate nucleotide analogs as antiviral agents
US5922695A (en) * 1996-07-26 1999-07-13 Gilead Sciences, Inc. Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
US20040224917A1 (en) 2003-01-14 2004-11-11 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004748A1 (en) * 1983-05-24 1984-12-06 Stanford Res Inst Int Novel antiviral agents
EP0173624A2 (en) * 1984-08-24 1986-03-05 Merck & Co. Inc. 4-(guanin-9-yl) butanals and antiviral compositions containing them

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004748A1 (en) * 1983-05-24 1984-12-06 Stanford Res Inst Int Novel antiviral agents
EP0173624A2 (en) * 1984-08-24 1986-03-05 Merck & Co. Inc. 4-(guanin-9-yl) butanals and antiviral compositions containing them

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Antiviral Research, volu *
Journal of Medicinal Che *

Also Published As

Publication number Publication date
NL8720745A (nl) 1988-12-01
SE8803309L (sv) 1988-09-19
WO1988005438A1 (en) 1988-07-28
EP0309491A1 (en) 1989-04-05
JPH01501864A (ja) 1989-06-29
SE8803309D0 (sv) 1988-09-19
DE3790883T1 (enExample) 1988-12-08
GB8821380D0 (en) 1988-11-02

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