GB2185026B - Thiolated nucleic acid derivatives. - Google Patents

Thiolated nucleic acid derivatives.

Info

Publication number
GB2185026B
GB2185026B GB8700183A GB8700183A GB2185026B GB 2185026 B GB2185026 B GB 2185026B GB 8700183 A GB8700183 A GB 8700183A GB 8700183 A GB8700183 A GB 8700183A GB 2185026 B GB2185026 B GB 2185026B
Authority
GB
United Kingdom
Prior art keywords
nucleic acid
acid derivatives
thiolated nucleic
thiolated
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8700183A
Other versions
GB2185026A (en
GB8700183D0 (en
Inventor
Junichi Yano
Tadaaki Ohgi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of GB8700183D0 publication Critical patent/GB8700183D0/en
Publication of GB2185026A publication Critical patent/GB2185026A/en
Application granted granted Critical
Publication of GB2185026B publication Critical patent/GB2185026B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB8700183A 1986-01-06 1987-01-06 Thiolated nucleic acid derivatives. Expired - Fee Related GB2185026B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP107686 1986-01-06

Publications (3)

Publication Number Publication Date
GB8700183D0 GB8700183D0 (en) 1987-02-11
GB2185026A GB2185026A (en) 1987-07-08
GB2185026B true GB2185026B (en) 1990-08-08

Family

ID=11491410

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8700183A Expired - Fee Related GB2185026B (en) 1986-01-06 1987-01-06 Thiolated nucleic acid derivatives.

Country Status (11)

Country Link
JP (1) JPS62252798A (en)
KR (1) KR940004076B1 (en)
BE (1) BE906157A (en)
CA (1) CA1315717C (en)
CH (1) CH671960A5 (en)
DE (1) DE3700164A1 (en)
ES (1) ES2004038A6 (en)
FR (1) FR2596762B1 (en)
GB (1) GB2185026B (en)
NL (1) NL8700016A (en)
SE (1) SE469594B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999061032A1 (en) * 1998-05-25 1999-12-02 Nippon Shinyaku Co., Ltd. Process for producing composite preparation containing nucleic acid
WO2003023031A1 (en) * 2001-09-04 2003-03-20 Nippon Shinyaku Co., Ltd. Method of evaluating efficacy of nucleic acid therapy

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB906851A (en) * 1960-05-03 1962-09-26 Schwarz Bio Res Inc Thiolation of polymers
GB1348289A (en) * 1970-08-22 1974-03-13 Merck Patent Gmbh Thiopyrimidine nucleotide derivatives processes for their pre paration and compositions containing them
GB1364987A (en) * 1971-06-19 1974-08-29 Merck Patent Gmbh Biologically active two component complexes
GB2038628A (en) * 1978-11-14 1980-07-30 Searle & Co Physiological compositions comprising poly(4-thiouridylic acid) or copolymers thereof and the use thereof as anti-viral agents or serum cholesterol lowering agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB906851A (en) * 1960-05-03 1962-09-26 Schwarz Bio Res Inc Thiolation of polymers
GB1348289A (en) * 1970-08-22 1974-03-13 Merck Patent Gmbh Thiopyrimidine nucleotide derivatives processes for their pre paration and compositions containing them
GB1364987A (en) * 1971-06-19 1974-08-29 Merck Patent Gmbh Biologically active two component complexes
GB2038628A (en) * 1978-11-14 1980-07-30 Searle & Co Physiological compositions comprising poly(4-thiouridylic acid) or copolymers thereof and the use thereof as anti-viral agents or serum cholesterol lowering agents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Ann. N.Y. Acad. Sci. 1975, 255, 532-543 *
Ann. N.Y. Acad. Sci. 1977, 284, 444-462 *

Also Published As

Publication number Publication date
SE8605616L (en) 1987-07-07
FR2596762A1 (en) 1987-10-09
DE3700164C2 (en) 1993-02-25
NL8700016A (en) 1987-08-03
KR940004076B1 (en) 1994-05-11
JPS62252798A (en) 1987-11-04
GB2185026A (en) 1987-07-08
DE3700164A1 (en) 1987-07-09
SE469594B (en) 1993-08-02
CA1315717C (en) 1993-04-06
GB8700183D0 (en) 1987-02-11
KR870007198A (en) 1987-08-17
SE8605616D0 (en) 1986-12-30
ES2004038A6 (en) 1988-12-01
FR2596762B1 (en) 1993-10-08
CH671960A5 (en) 1989-10-13
BE906157A (en) 1987-07-01

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950106