GB2133002B - Process for preparing 4-amino-5-hexenoic acid - Google Patents

Process for preparing 4-amino-5-hexenoic acid

Info

Publication number
GB2133002B
GB2133002B GB08236998A GB8236998A GB2133002B GB 2133002 B GB2133002 B GB 2133002B GB 08236998 A GB08236998 A GB 08236998A GB 8236998 A GB8236998 A GB 8236998A GB 2133002 B GB2133002 B GB 2133002B
Authority
GB
United Kingdom
Prior art keywords
amino
preparing
hexenoic acid
hexenoic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08236998A
Other languages
English (en)
Other versions
GB2133002A (en
Inventor
Wolfgang Frieben
Fritz Gerhart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Priority to GB08236998A priority Critical patent/GB2133002B/en
Priority to US06/556,204 priority patent/US4621145A/en
Priority to JP58244367A priority patent/JPS59130863A/ja
Priority to IL8189883A priority patent/IL81898A/xx
Priority to IL70545A priority patent/IL70545A/xx
Priority to EP83440068A priority patent/EP0116257B1/fr
Priority to DE198383440068T priority patent/DE116257T1/de
Priority to DE8383440068T priority patent/DE3365732D1/de
Priority to CA000444331A priority patent/CA1208651A/fr
Priority to IE3078/83A priority patent/IE56543B1/en
Publication of GB2133002A publication Critical patent/GB2133002A/en
Priority to CA000497324A priority patent/CA1216299A/fr
Application granted granted Critical
Publication of GB2133002B publication Critical patent/GB2133002B/en
Priority to IL81898A priority patent/IL81898A0/xx
Priority to JP4129894A priority patent/JPH0629240B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08236998A 1982-12-30 1982-12-30 Process for preparing 4-amino-5-hexenoic acid Expired GB2133002B (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
GB08236998A GB2133002B (en) 1982-12-30 1982-12-30 Process for preparing 4-amino-5-hexenoic acid
US06/556,204 US4621145A (en) 1982-12-30 1983-11-29 Process for preparing 5-vinyl-2-pyrrolidinone and intermediates therefor
IL8189883A IL81898A (en) 1982-12-30 1983-12-26 Process for preparing 4-amino-5-hexenoic acid
IL70545A IL70545A (en) 1982-12-30 1983-12-26 Process for preparing 5-vinyl-2-pyrrolidinone and novel intermediate therefor
JP58244367A JPS59130863A (ja) 1982-12-30 1983-12-26 ５―ビニル―２―ピロリジノンの製法
DE198383440068T DE116257T1 (de) 1982-12-30 1983-12-27 Verfahren zur herstellung von 4-amino-5-hexensaeure.
EP83440068A EP0116257B1 (fr) 1982-12-30 1983-12-27 Procédé pour la préparation de l'acide 4-amino-5-hexénoique
DE8383440068T DE3365732D1 (en) 1982-12-30 1983-12-27 Process for preparing 4-amino-5-hexenoic acid
CA000444331A CA1208651A (fr) 1982-12-30 1983-12-28 Methode de preparation d'acide 4-amino-5-hexenoique
IE3078/83A IE56543B1 (en) 1982-12-30 1983-12-29 Process for preparing 4-amino-5-hexenoic acid
CA000497324A CA1216299A (fr) 1982-12-30 1985-12-10 Methode de preparation d'acide 4-amino-5-hexenoique
IL81898A IL81898A0 (en) 1982-12-30 1987-03-16 Process for preparing 4-amino-5-hexenoic acid
JP4129894A JPH0629240B2 (ja) 1982-12-30 1992-04-24 Ｎ，ｎ−ジメチル−２−〔５’−オキソ−２’−ピロリジン〕エチルアミン、そのｎ−オキシド及び製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08236998A GB2133002B (en) 1982-12-30 1982-12-30 Process for preparing 4-amino-5-hexenoic acid

Publications (2)

Publication Number Publication Date
GB2133002A GB2133002A (en) 1984-07-18
GB2133002B true GB2133002B (en) 1986-01-29

Family

ID=10535295

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08236998A Expired GB2133002B (en) 1982-12-30 1982-12-30 Process for preparing 4-amino-5-hexenoic acid

Country Status (8)

Country Link
US (1) US4621145A (fr)
EP (1) EP0116257B1 (fr)
JP (2) JPS59130863A (fr)
CA (1) CA1208651A (fr)
DE (2) DE116257T1 (fr)
GB (1) GB2133002B (fr)
IE (1) IE56543B1 (fr)
IL (1) IL70545A (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632994A (en) * 1983-11-04 1986-12-30 Gruppo Lepetit S.P.A. Process for decomposing N-oxide derivatives producing 5-vinyl-2-pyrrolidones
DE3718563A1 (de) * 1987-06-03 1988-12-15 Basf Ag Verfahren zur herstellung von substituierten lactamen
CA2028782C (fr) * 1989-11-07 2003-10-14 Christian T. Goralski Methode de production de vinyle-gaba
IL100360A (en) * 1990-12-17 1998-08-16 Merrell Dow Pharma HISTORY OF PYROLIDINONE USED AS SUBSTANCE (S) -Vinyl and Alanyl GABA
US5208345A (en) * 1990-12-17 1993-05-04 Merrell Dow Pharmaceuticals Inc. Process for the production of (S)-vinyl and allenyl gaba
EP0546230A1 (fr) * 1991-12-10 1993-06-16 Merrell Dow Pharmaceuticals Inc. Nouveau procédé pour la préparation de l'acide 4-amino 5-hexénoique
US5316944A (en) * 1992-07-17 1994-05-31 Merrell Dow Pharmaceuticals Enzymatic resolution of a racemic mixture of gamma-amino acids using penicillin acylase
DE4420751A1 (de) 1994-06-15 1995-12-21 Basf Ag Verfahren zur Herstellung von enantiomerenreinen Lactamen
US6057368A (en) * 1998-08-05 2000-05-02 Brookhaven Science Associates Llc Treatment of addiction and addiction-related behavior
US6541520B1 (en) 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
US6890951B2 (en) 1998-08-05 2005-05-10 Brookhaven Science Associates Llc Treatment of addiction and addiction-related behavior
CA2341400A1 (fr) * 1998-08-25 2000-03-02 Sepracor, Inc. Procedes et compositions employant le vigabatrin s(+) optiquement pur
DE19910504A1 (de) * 1999-03-10 2000-09-14 Basf Ag Verfahren zur Reinigung von N-substituierten Lactamen
US6395783B1 (en) 2000-10-23 2002-05-28 Brookhaven Science Associates, Llc Treatment of PCP addiction and PCP addiction-related behavior
EP2537827B1 (fr) 2011-06-24 2014-06-11 Targeon SAS Procédé pour la préparation d'acide 4-amino-5-hexénoïque du succinimide
WO2019180547A1 (fr) * 2018-03-20 2019-09-26 Aurobindo Pharma Limited Procédé de préparation de vigabatrine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1363712A (fr) * 1963-07-18 1964-06-12 Basf Ag Procédé pour la production d'acide omega-aminododécanoïque
US3959356A (en) * 1975-03-18 1976-05-25 Richardson-Merrell Inc. Acetylene derivatives of amino acids
US3960927A (en) * 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
US4178463A (en) * 1978-01-30 1979-12-11 Merrell Toraude Et Compagnie Process for making 4-aminohex-5-enoic acid

Also Published As

Publication number Publication date
DE3365732D1 (en) 1986-10-02
IL70545A (en) 1988-03-31
IE56543B1 (en) 1991-08-28
EP0116257A1 (fr) 1984-08-22
IL70545A0 (en) 1984-03-30
JPS59130863A (ja) 1984-07-27
JPH0463873B2 (fr) 1992-10-13
EP0116257B1 (fr) 1986-08-27
US4621145A (en) 1986-11-04
CA1208651A (fr) 1986-07-29
IE833078L (en) 1984-06-30
JPH0629240B2 (ja) 1994-04-20
JPH05320129A (ja) 1993-12-03
GB2133002A (en) 1984-07-18
DE116257T1 (de) 1985-02-28

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20021229