GB2132890A - Oral veterinary drug - Google Patents

Oral veterinary drug Download PDF

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Publication number
GB2132890A
GB2132890A GB08400180A GB8400180A GB2132890A GB 2132890 A GB2132890 A GB 2132890A GB 08400180 A GB08400180 A GB 08400180A GB 8400180 A GB8400180 A GB 8400180A GB 2132890 A GB2132890 A GB 2132890A
Authority
GB
United Kingdom
Prior art keywords
drug
granules
tablet
veterinary
flavoured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB08400180A
Other versions
GB8400180D0 (en
GB2132890B (en
Inventor
Andrew Macarthy Reynolds
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838300317A external-priority patent/GB8300317D0/en
Application filed by Individual filed Critical Individual
Priority to GB08400180A priority Critical patent/GB2132890B/en
Publication of GB8400180D0 publication Critical patent/GB8400180D0/en
Publication of GB2132890A publication Critical patent/GB2132890A/en
Application granted granted Critical
Publication of GB2132890B publication Critical patent/GB2132890B/en
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)

Abstract

A drug formulation has small individually flavoured granules to alleviate any objectionable taste associated with the drug. The individual granules can be coated or impregnated with flavour and then formed into tablets. The tablets may be further coated with flavour. Suitable flavours are aniseed, chocolate, liver, sugar, rabbit, beef, chicken or a neutral flavour such as gelatin.

Description

SPECIFICATION Veterinary drug for oral administration This invention relates to veterinary drugs. When an animal is treated by a veterinary surgeon, the surgeon may administer a drug intravenously.
However, when an animal such as a cat or dog is to be given a drug at home without a vet being present, it is not usually possible for a drug to be administered intravenously because most people lack either the necessary skill and/or the inclination to give injections.
The obvious solution is to provide veterinary drugs for oral adminstration, and indeed such drugs are currently available. However, it has been found that it is difficult to persuade animals to take the currently available drugs because of the objectionable flavour and/or odour of many drugs. It would be possible to provide a pleasantly flavoured coating for a veterinary tablet and this would help to some extent. However, in general animals chew all food thoroughly, and so an animal would soon chew through to the unpleasantly flavoured interior of the tablet and would spit it out.
Owners of pets may be familiar with the problem described above and may have expended considerable time and effort in trying in cajole or trick an animal into taking a tablet by hiding the tablet in food. Such efforts are frequently unsuccessful.
An aim of this invention is to provide a veterinary drug for oral adminstration which will overcome or alleviate the problems described above.
According to one aspect of this invention, a veterinary drug for oral administration can take the form of small drug granules (which may be similar in size to the small sweets commonly known as hundred and thousands) each individual granule being coated and/or impregnated with a suitable flavouring material.
The individual granules can subsequently be formed into tablets with the use of a binder and/or by compression, and if desired the tablet thus formed can again be provided with a coating of a suitable flavouring material.
As an alternative, the drug can remain in granular form, and if desired can be sprinkled on an animal food.
Suitable flavours for the flavouring material are aniseed, chocolate, liver, sugar, rabbit, beef and chicken. The invention also includesthe use of "neutral" flavours such as gelatin.
Where the flavouring material is to be applied as a coating, then it may be in the form of a paste or liquid which sets, and where the flavouring material is to impregnate the interior of the granules, it may be in the form of a liquidm paste, or powder. In the latter case, the flavouring material may be intimately mixed with the basic ingredients of the drug before the granules are formed. The basic ingredients of the drug will be conventional.
The precise size of the granules is not critical, and any size between 0.001 inches and 1/t' inch in diameter may be suitable, for example between 0.005 inches and .08 inches.
The material forming each granule may originally be in powder form and may be held together by a conventional binder.
An animal, for example a pet, will find a drug acording to the invention to be more acceptable than a normal coated tablet because the normal flavour of the drug is well masked by forming the drug in small flavoured granules.
1. A veterinary drug for oral administration comprising granules which are each flavoured.
2. A veterinary drug for oral adminstration comprising granules of drug material which are individually impregnated and/or coated with a flavouring material.
3. A drug according to claim 2, in which the granules are of the same size as the well known small sweets called "hundreds and thousands".
4. A drug according to claim 2, in which the granules are between 0.001 inches and 1/8 inch in diameter.
5. A drug according to claim 4, in which the granules are between 0.005 inches and .08 inches in diameter.
6. A drug according to any preceding claim, in which the flavour of the flavouring material is selected from aniseed, chocolate, liver, sugar, rabbit, beef, chicken and gelatin.
7. A drug according to any preceding claim, in which the drug is supplied in the form of granules which may, if desired, be sprinkled onto an animals food.
8. A drug according to any of claims 1 to 6, in which the flavoured granules are formed into a tablet.
9. A tablet according to claim 8 in which the tablet is itself coated with a flavoured coating.
**WARNING** end of DESC field may overlap start of CLMS **.

Claims (9)

**WARNING** start of CLMS field may overlap end of DESC **. SPECIFICATION Veterinary drug for oral administration This invention relates to veterinary drugs. When an animal is treated by a veterinary surgeon, the surgeon may administer a drug intravenously. However, when an animal such as a cat or dog is to be given a drug at home without a vet being present, it is not usually possible for a drug to be administered intravenously because most people lack either the necessary skill and/or the inclination to give injections. The obvious solution is to provide veterinary drugs for oral adminstration, and indeed such drugs are currently available. However, it has been found that it is difficult to persuade animals to take the currently available drugs because of the objectionable flavour and/or odour of many drugs. It would be possible to provide a pleasantly flavoured coating for a veterinary tablet and this would help to some extent. However, in general animals chew all food thoroughly, and so an animal would soon chew through to the unpleasantly flavoured interior of the tablet and would spit it out. Owners of pets may be familiar with the problem described above and may have expended considerable time and effort in trying in cajole or trick an animal into taking a tablet by hiding the tablet in food. Such efforts are frequently unsuccessful. An aim of this invention is to provide a veterinary drug for oral adminstration which will overcome or alleviate the problems described above. According to one aspect of this invention, a veterinary drug for oral administration can take the form of small drug granules (which may be similar in size to the small sweets commonly known as hundred and thousands) each individual granule being coated and/or impregnated with a suitable flavouring material. The individual granules can subsequently be formed into tablets with the use of a binder and/or by compression, and if desired the tablet thus formed can again be provided with a coating of a suitable flavouring material. As an alternative, the drug can remain in granular form, and if desired can be sprinkled on an animal food. Suitable flavours for the flavouring material are aniseed, chocolate, liver, sugar, rabbit, beef and chicken. The invention also includesthe use of "neutral" flavours such as gelatin. Where the flavouring material is to be applied as a coating, then it may be in the form of a paste or liquid which sets, and where the flavouring material is to impregnate the interior of the granules, it may be in the form of a liquidm paste, or powder. In the latter case, the flavouring material may be intimately mixed with the basic ingredients of the drug before the granules are formed. The basic ingredients of the drug will be conventional. The precise size of the granules is not critical, and any size between 0.001 inches and 1/t' inch in diameter may be suitable, for example between 0.005 inches and .08 inches. The material forming each granule may originally be in powder form and may be held together by a conventional binder. An animal, for example a pet, will find a drug acording to the invention to be more acceptable than a normal coated tablet because the normal flavour of the drug is well masked by forming the drug in small flavoured granules. CLAIMS
1. A veterinary drug for oral administration comprising granules which are each flavoured.
2. A veterinary drug for oral adminstration comprising granules of drug material which are individually impregnated and/or coated with a flavouring material.
3. A drug according to claim 2, in which the granules are of the same size as the well known small sweets called "hundreds and thousands".
4. A drug according to claim 2, in which the granules are between 0.001 inches and 1/8 inch in diameter.
5. A drug according to claim 4, in which the granules are between 0.005 inches and .08 inches in diameter.
6. A drug according to any preceding claim, in which the flavour of the flavouring material is selected from aniseed, chocolate, liver, sugar, rabbit, beef, chicken and gelatin.
7. A drug according to any preceding claim, in which the drug is supplied in the form of granules which may, if desired, be sprinkled onto an animals food.
8. A drug according to any of claims 1 to 6, in which the flavoured granules are formed into a tablet.
9. A tablet according to claim 8 in which the tablet is itself coated with a flavoured coating.
GB08400180A 1983-01-06 1984-01-05 Oral veterinary drug Expired GB2132890B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB08400180A GB2132890B (en) 1983-01-06 1984-01-05 Oral veterinary drug

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838300317A GB8300317D0 (en) 1983-01-06 1983-01-06 Veterinary drugs
GB08400180A GB2132890B (en) 1983-01-06 1984-01-05 Oral veterinary drug

Publications (3)

Publication Number Publication Date
GB8400180D0 GB8400180D0 (en) 1984-02-08
GB2132890A true GB2132890A (en) 1984-07-18
GB2132890B GB2132890B (en) 1986-12-03

Family

ID=26284847

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08400180A Expired GB2132890B (en) 1983-01-06 1984-01-05 Oral veterinary drug

Country Status (1)

Country Link
GB (1) GB2132890B (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB835932A (en) * 1956-03-27 1960-05-25 Ciba Ltd Process for the manufacture of therapeutic tablet granulations
GB844772A (en) * 1956-04-19 1960-08-17 Pfizer & Co C Granular pharmaceutical compositions and process for preparing same
GB1200906A (en) * 1966-12-01 1970-08-05 Ferrosan As Vitamin compositions
GB1296944A (en) * 1970-02-23 1972-11-22
GB1458431A (en) * 1973-03-16 1976-12-15 Meiji Seika Co Preparation of granules
GB1564687A (en) * 1977-02-17 1980-04-10 Merck Patent Gmbh Ascorbic acid-containing granulates

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB835932A (en) * 1956-03-27 1960-05-25 Ciba Ltd Process for the manufacture of therapeutic tablet granulations
GB844772A (en) * 1956-04-19 1960-08-17 Pfizer & Co C Granular pharmaceutical compositions and process for preparing same
GB1200906A (en) * 1966-12-01 1970-08-05 Ferrosan As Vitamin compositions
GB1296944A (en) * 1970-02-23 1972-11-22
GB1458431A (en) * 1973-03-16 1976-12-15 Meiji Seika Co Preparation of granules
GB1564687A (en) * 1977-02-17 1980-04-10 Merck Patent Gmbh Ascorbic acid-containing granulates

Also Published As

Publication number Publication date
GB8400180D0 (en) 1984-02-08
GB2132890B (en) 1986-12-03

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950105