GB2110089A - Device for sterilizing articles and environment - Google Patents
Device for sterilizing articles and environment Download PDFInfo
- Publication number
- GB2110089A GB2110089A GB08203683A GB8203683A GB2110089A GB 2110089 A GB2110089 A GB 2110089A GB 08203683 A GB08203683 A GB 08203683A GB 8203683 A GB8203683 A GB 8203683A GB 2110089 A GB2110089 A GB 2110089A
- Authority
- GB
- United Kingdom
- Prior art keywords
- probiocide
- article
- disinfecting
- controlling
- micro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000001954 sterilising effect Effects 0.000 title description 11
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims abstract description 18
- 244000005700 microbiome Species 0.000 claims abstract description 16
- 229920000642 polymer Polymers 0.000 claims abstract description 15
- 230000003115 biocidal effect Effects 0.000 claims abstract description 14
- 239000003139 biocide Substances 0.000 claims abstract description 12
- 239000004094 surface-active agent Substances 0.000 claims abstract description 11
- 239000001569 carbon dioxide Substances 0.000 claims abstract description 9
- 229910002092 carbon dioxide Inorganic materials 0.000 claims abstract description 9
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims description 60
- -1 alkali metal bicarbonate Chemical class 0.000 claims description 19
- 238000004519 manufacturing process Methods 0.000 claims description 15
- 229930040373 Paraformaldehyde Natural products 0.000 claims description 13
- 229920002866 paraformaldehyde Polymers 0.000 claims description 11
- 230000000249 desinfective effect Effects 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 8
- VKYKSIONXSXAKP-UHFFFAOYSA-N hexamethylenetetramine Chemical group C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 235000010299 hexamethylene tetramine Nutrition 0.000 claims description 6
- 229960004011 methenamine Drugs 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 6
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 229910052783 alkali metal Inorganic materials 0.000 claims description 4
- 229910000288 alkali metal carbonate Inorganic materials 0.000 claims description 3
- 150000008041 alkali metal carbonates Chemical class 0.000 claims description 3
- 125000005704 oxymethylene group Chemical group [H]C([H])([*:2])O[*:1] 0.000 claims description 3
- 150000007524 organic acids Chemical class 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 2
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 abstract description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 15
- 235000019256 formaldehyde Nutrition 0.000 description 15
- 239000000203 mixture Substances 0.000 description 13
- 229920001577 copolymer Polymers 0.000 description 8
- 239000008098 formaldehyde solution Substances 0.000 description 8
- 239000000243 solution Substances 0.000 description 7
- 230000001276 controlling effect Effects 0.000 description 5
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000011159 matrix material Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
- 125000003118 aryl group Chemical group 0.000 description 3
- 239000000645 desinfectant Substances 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- 239000000194 fatty acid Substances 0.000 description 3
- 229930195729 fatty acid Natural products 0.000 description 3
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- 239000012530 fluid Substances 0.000 description 3
- 229920000570 polyether Polymers 0.000 description 3
- 229920002554 vinyl polymer Polymers 0.000 description 3
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 2
- MSJLMQTXVKCUCD-UHFFFAOYSA-M 2-dodecylisoquinolin-2-ium;bromide Chemical compound [Br-].C1=CC=CC2=C[N+](CCCCCCCCCCCC)=CC=C21 MSJLMQTXVKCUCD-UHFFFAOYSA-M 0.000 description 2
- XZIIFPSPUDAGJM-UHFFFAOYSA-N 6-chloro-2-n,2-n-diethylpyrimidine-2,4-diamine Chemical compound CCN(CC)C1=NC(N)=CC(Cl)=N1 XZIIFPSPUDAGJM-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 2
- 239000004721 Polyphenylene oxide Substances 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 2
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 2
- 150000001241 acetals Chemical class 0.000 description 2
- 150000001336 alkenes Chemical class 0.000 description 2
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000005038 ethylene vinyl acetate Substances 0.000 description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 2
- UXNFIJPHRQEWRQ-UHFFFAOYSA-N hexamethylenetetramine mandelate salt Chemical compound C1N(C2)CN3CN1CN2C3.OC(=O)C(O)C1=CC=CC=C1 UXNFIJPHRQEWRQ-UHFFFAOYSA-N 0.000 description 2
- 229960002786 methenamine mandelate Drugs 0.000 description 2
- 238000003801 milling Methods 0.000 description 2
- 235000016337 monopotassium tartrate Nutrition 0.000 description 2
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 2
- 230000037081 physical activity Effects 0.000 description 2
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 2
- 229920006324 polyoxymethylene Polymers 0.000 description 2
- KYKNRZGSIGMXFH-ZVGUSBNCSA-M potassium bitartrate Chemical compound [K+].OC(=O)[C@H](O)[C@@H](O)C([O-])=O KYKNRZGSIGMXFH-ZVGUSBNCSA-M 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 230000000979 retarding effect Effects 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 229940035044 sorbitan monolaurate Drugs 0.000 description 2
- 239000001593 sorbitan monooleate Substances 0.000 description 2
- 235000011069 sorbitan monooleate Nutrition 0.000 description 2
- 229940035049 sorbitan monooleate Drugs 0.000 description 2
- 229920003048 styrene butadiene rubber Polymers 0.000 description 2
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 description 1
- QLZJUIZVJLSNDD-UHFFFAOYSA-N 2-(2-methylidenebutanoyloxy)ethyl 2-methylidenebutanoate Chemical compound CCC(=C)C(=O)OCCOC(=O)C(=C)CC QLZJUIZVJLSNDD-UHFFFAOYSA-N 0.000 description 1
- WJYAJBDKANFOID-UHFFFAOYSA-N 2-(dodecylamino)propanoic acid Chemical compound CCCCCCCCCCCCNC(C)C(O)=O WJYAJBDKANFOID-UHFFFAOYSA-N 0.000 description 1
- HPKFFZSXDWPVLX-UHFFFAOYSA-N 2-[(2-pyridin-1-ium-1-ylacetyl)amino]ethyl dodecanoate;chloride Chemical compound [Cl-].CCCCCCCCCCCC(=O)OCCNC(=O)C[N+]1=CC=CC=C1 HPKFFZSXDWPVLX-UHFFFAOYSA-N 0.000 description 1
- ZQHIJEMEJWVSEZ-UHFFFAOYSA-M 2-ethoxyethyl-dimethyl-[[1-(2-methylpropyl)cyclohexa-2,4-dien-1-yl]oxy-[4-(2-methylpropyl)phenyl]methyl]azanium chloride Chemical compound [Cl-].C(C(C)C)C1(OC(C2=CC=C(C=C2)CC(C)C)[N+](C)(C)CCOCC)CC=CC=C1 ZQHIJEMEJWVSEZ-UHFFFAOYSA-M 0.000 description 1
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 description 1
- 241000228197 Aspergillus flavus Species 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 241000222290 Cladosporium Species 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 241000588914 Enterobacter Species 0.000 description 1
- 241000194032 Enterococcus faecalis Species 0.000 description 1
- 241001480036 Epidermophyton floccosum Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 description 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000228402 Histoplasma Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 241000588748 Klebsiella Species 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229930183781 Mycobactin Natural products 0.000 description 1
- IGFHQQFPSIBGKE-UHFFFAOYSA-N Nonylphenol Natural products CCCCCCCCCC1=CC=C(O)C=C1 IGFHQQFPSIBGKE-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 241000588767 Proteus vulgaris Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000235546 Rhizopus stolonifer Species 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 241001045770 Trichophyton mentagrophytes Species 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical class OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 229920002433 Vinyl chloride-vinyl acetate copolymer Polymers 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- LUXUAZKGQZPOBZ-SAXJAHGMSA-N [(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (Z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O LUXUAZKGQZPOBZ-SAXJAHGMSA-N 0.000 description 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
- 239000003377 acid catalyst Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 229920006243 acrylic copolymer Polymers 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 150000008055 alkyl aryl sulfonates Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 125000002947 alkylene group Chemical group 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000001099 ammonium carbonate Substances 0.000 description 1
- 235000012501 ammonium carbonate Nutrition 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- JXLHNMVSKXFWAO-UHFFFAOYSA-N azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid Chemical compound N.OS(=O)(=O)C1=CC=C(F)C2=NON=C12 JXLHNMVSKXFWAO-UHFFFAOYSA-N 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 150000007514 bases Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- JBIROUFYLSSYDX-UHFFFAOYSA-M benzododecinium chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 JBIROUFYLSSYDX-UHFFFAOYSA-M 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 239000007859 condensation product Substances 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- KSDGSKVLUHKDAL-UHFFFAOYSA-L disodium;3-[2-carboxylatoethyl(dodecyl)amino]propanoate Chemical compound [Na+].[Na+].CCCCCCCCCCCCN(CCC([O-])=O)CCC([O-])=O KSDGSKVLUHKDAL-UHFFFAOYSA-L 0.000 description 1
- FXPVUWKFNGVHIZ-UHFFFAOYSA-L disodium;dodecyl sulfate Chemical compound [Na+].[Na+].CCCCCCCCCCCCOS([O-])(=O)=O.CCCCCCCCCCCCOS([O-])(=O)=O FXPVUWKFNGVHIZ-UHFFFAOYSA-L 0.000 description 1
- MOTZDAYCYVMXPC-UHFFFAOYSA-N dodecyl hydrogen sulfate Chemical compound CCCCCCCCCCCCOS(O)(=O)=O MOTZDAYCYVMXPC-UHFFFAOYSA-N 0.000 description 1
- 125000002573 ethenylidene group Chemical group [*]=C=C([H])[H] 0.000 description 1
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 description 1
- VUFOSBDICLTFMS-UHFFFAOYSA-M ethyl-hexadecyl-dimethylazanium;bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)CC VUFOSBDICLTFMS-UHFFFAOYSA-M 0.000 description 1
- 229920006244 ethylene-ethyl acrylate Polymers 0.000 description 1
- 239000005042 ethylene-ethyl acrylate Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 150000002462 imidazolines Chemical class 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- DXPBGQWPULFACQ-UHFFFAOYSA-N methenamine salicylate Chemical compound C1N(C2)CN3CN1CN2C3.OC(=O)C1=CC=CC=C1O DXPBGQWPULFACQ-UHFFFAOYSA-N 0.000 description 1
- 229960003412 methenamine sulfosalicylate Drugs 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- HWPKGOGLCKPRLZ-UHFFFAOYSA-M monosodium citrate Chemical compound [Na+].OC(=O)CC(O)(C([O-])=O)CC(O)=O HWPKGOGLCKPRLZ-UHFFFAOYSA-M 0.000 description 1
- 235000018342 monosodium citrate Nutrition 0.000 description 1
- 239000002524 monosodium citrate Substances 0.000 description 1
- XZGYBQIQSLSHDH-COEJQBHMSA-N mycobactin Chemical compound C1CCCN(O)C(=O)C1NC(=O)C(C)C(CC)OC(=O)C(CCCCN(O)C(=O)\C=C/CCCCCCCCCCCCCCC)NC(=O)C(N=1)COC=1C1=C(C)C=CC=C1O XZGYBQIQSLSHDH-COEJQBHMSA-N 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- 229940083254 peripheral vasodilators imidazoline derivative Drugs 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
- 229920002037 poly(vinyl butyral) polymer Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920001748 polybutylene Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000151 polyglycol Polymers 0.000 description 1
- 239000010695 polyglycol Substances 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920000259 polyoxyethylene lauryl ether Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229940081543 potassium bitartrate Drugs 0.000 description 1
- 235000011181 potassium carbonates Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 150000003334 secondary amides Chemical class 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Substances [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
- 235000011182 sodium carbonates Nutrition 0.000 description 1
- JVBXVOWTABLYPX-UHFFFAOYSA-L sodium dithionite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])=O JVBXVOWTABLYPX-UHFFFAOYSA-L 0.000 description 1
- RTVVXRKGQRRXFJ-UHFFFAOYSA-N sodium;2-sulfobutanedioic acid Chemical compound [Na].OC(=O)CC(C(O)=O)S(O)(=O)=O RTVVXRKGQRRXFJ-UHFFFAOYSA-N 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- SFVFIFLLYFPGHH-UHFFFAOYSA-M stearalkonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 SFVFIFLLYFPGHH-UHFFFAOYSA-M 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- PCWIMOMJMPZZMW-UHFFFAOYSA-M trimethyl-[(2-methylphenyl)methyl]azanium;chloride Chemical compound [Cl-].CC1=CC=CC=C1C[N+](C)(C)C PCWIMOMJMPZZMW-UHFFFAOYSA-M 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- AFOTXNKRSJVXBS-UHFFFAOYSA-N uropurat Chemical compound C1N(C2)CN3CN1CN2C3.OC(=O)C1=CC(S(O)(=O)=O)=CC=C1O AFOTXNKRSJVXBS-UHFFFAOYSA-N 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Chemical & Material Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
A device for controlling the presence of unwanted microorganisms comprising a polymer comprising a probiocide that produces the biocide formaldehyde, an effervescent couple for evolving carbon dioxide, and optionally a surfactant.
Description
SPECIFICATION
Device for sterilizing articles and enviroment
Field of the Invention
This invention pertains to a device useful for sterilizing medical, surgical, dental, laboratory and other articles of manufacture, and for sterilizing selected environments for use. The device comprises (1) a polymer that houses (2) a probiocide that produces the biocide formaldehyde, (3) an effervescent couple, and (4) optionally a surfactant.
Background of the Invention
It is frequently recognized that it is very advantageous to sterilize and substantially maintain certain articles of manufacture substantially free of unwanted micro-organisms, and also to control the presence to unwanted micro-organisms in preselected enviroments of use. One agent that is widely used for these purposes is formaldehyde solution, also known as formalin. Formaldehyde solution consists of about 37% by weight of formaldehyde gas in water, and it usually has methanol added thereto for preventing polymerization. This solution is full strength, and it is also known as formalin 100% or formalin 40.
This latter designation indicates that it contains 40 grams of formaldehyde within 100 milliliters of the solution.
While formaldehyde solution is used by the medical and dental professions for sterilizing medical, surgical and dental instruments, and by research and commercial users for sterilizing other instruments and applicances, and also for disinfecting certain areas, there are disadvantages associated with the use of formaldehyde solution. For example, formaldehyde solution commonly is used as a previously prepared stock solution, and this has the inherent disadvantage that formaldehyde vapors can continuously escape from the solution, and thereby make it iess effective for its intended purpose. Another disadvantage is that formaldehyde solution is heavy and expensive to ship which increases the cost of using it for sterilizing and disinfecting articles and enviroments.Also, formaldehyde solution is bulky and it requires cumbersome packaging, that is often damaged and leaks during transport.
In view of the above presentation, it will be appreciated that because of the disadvantages associated with already prepared formaldehyde solutions, a critical need exists for a device that can supply on request a formaldehyde solution useful for producing the intended results of sterilizing and controlling the presence of of unwanted micro-organisms.
Brief Description of Drawing
In the drawing, which is not drawn to scale, but it set forth to illustrate an embodiment of the invention, the figure is as follows:
Figure 1 is a perspective view, with a part broken away, for illustrating the structure of a device provided by the invention.
Detailed Description of the Invention
The expression "controlling the presence of micro-organisms" as used herein denotes in the context of this invention killing, preventing and/or retarding the presence, or the propagation of micro-organisms in a preselected "environment of use". The phrase "environment of use" includes using the device provided by this invention for controlling the presence of unwanted micro-organisms in selected areas such as hospital rooms, operating rooms, military room, laboratories, dwellings, ships, railroad cars, stagnant water, animal dips, and the like.
The terms "biocide", "sterilizing", and disinfectant", as used herein refer to the ability of the device of the invention to furnish formaldehyde for killing, cleansing, preventing, and/or retarding the presence, or the propagation of harmful unwanted micro-organisms on instruments and other articles of manufacture. The term "instruments" includes medical, surgical, dental, laboratory and barber instruments. The phrase "articles of manufacture" includes garbage cans, germfree boxes, containers, contact lens receptacles, urine receptacles and the like.
The phrase "unwanted micro-organism" as used herein includes bacteria, spirochettes, viruses, spores, fungi, mycobactin, and the like. The micro-organismd include Aspergillus niger, Aspergillus flavus, Rhizopus nigricans,
Cladosporium herbarium, Epidermophyton floccosum, Trichophyton mentagrophytes, Histoplasma capsulation, and the like. The phrase also includes antibacterial activity against
Pseudomonas aeruginosa, Escherichia coli,
Proteus vulgaris, Staphylococcus aureus,
Streptococcus faecalis, Klebsiella, Enterobacter areogenes, Proteus micabilis, and the like.
The term also embraces yeast such as Saccharomyces cerevisiae, Candida albicans, and the like.
The device of the invention as exemplified by Fig. 1, and identified by the numeral 10 has at least one or more surfaces for dispensing the active agent, and it has a body 11 adapted, shaped and sized for placing in an enviroment of use or for sterilizing an article for manufacute. Device 10 can embrace any shape such as square, round, rectangle, triangle, crescent and the like. Device 10 can be manufactured as a sheet, strip, envelope, rod, matrix, sponge, prism of various cross-section such as cruciform or hexagonal, and the like.
In the embodiment illustrated in Fig. 1, device 10 is container shaped and it has a lead end 12 and a trailing end 13. Device 10 is seen in opened section 1 4 and it comprises a polymer 1 5 having dispersed therein a probiocide 16, an effervescent couple 17, and optionally a surfactant 1 8. Device 10 optionally is sized to fit the need and it can have various dimensions. For example, device 10 when manufactured as a matrix can have a length of 5 millimeters to 20 centimeters or more, a width of 5 millimeters to 10 centimeters or more, and a thickness of 1 millimeter to 5 millimeters or more. Device 10 also can be designed and manufactured for immediate use, or for use over a prolonge period of time, such as 5 to 40 days, or longer.
Representative of polymers 1 5 used for manufacturing device 10 include polymers that permit the passage of fluid, mainly water.
The polymers are exemplified by acrylic polymers and copolymers of methacrylate, ethylacrylate, ethylmethacrylate and methacrylate; homopolymers and copolymers of vinyl chloride including vinyl chloride-vinyl acetate copolymers; chlorinated vinyl chloride; polyethylene; polyproplylene; ethylene-propylene copolymer; chlorinated polyethyelene; ethylenevinyl acetate copolymer; styrene-butadiene copolymer; acrylonitrite-styrene-butadiene copolymer; polyvinylidene chloride; vinyl chloride-vinylidene chloride copolymers; vinylidene chloride-acrylonitrite copolymer; vinylidene chloride-acrylate ester copolymer; polybutylene terphthalate; vinyl chloride-acrylate ester copolymer; polyvinyl acetals such as polyvinyl formal, polyvinyl acetal and polyvinyl butyral; polyethers; polyesters; polyurethanes; halogenated-sulfonated polyolefins; polyisoprene; silicone, and the like.
The probiocide useful for the present purpose are materials, which in the presence of moisture generate the biocide formaldehyde.
One probiocide suitable for this purpose is paraformaldehyde. The paraformaldehyde is a member selected from the group consisting of the cyclic tripolymer of the general formula (CH2O)n wherein n is 3, and the linear polymer of the general formula HO(CH2O)rnH wherein m is 3 to 200. These polymers in the presence of moisture that enters the device undergo depolymerization to yield the water soluble biocide and disinfectant formaldehyde.
The amount of paraformaldehyde, cyclic or linear, in a device generally is about 2% to 80% by weight based on the total weight of the deivce, and more preferably about 30 to 60% of the device.
Another probiocide useful for producing the biocide that can be incorporated into the device is methenamine, its acid addition and quarternary salts. The biocide activity of a methenamine salt stems from the hydrolysis of methenamine to formaldehyde and the biocidal activity of the acid moiety of the salt.
Exemplary compounds include methenamine mandelate, methenamine salicylate, methenamine sulfosalicylate and methenamine tetraiodide. The amount of methenamine salt in a device is generally about 2% to 80% by weight based on the total weight of the device, and more preferably about 30% to 60% of the device. The device can also house both paraformaldehyde and methenamine in a total amount of about 40 to 80% of the device.
The device also can contain polyoxymethylene esters and polyoxymethylene diesters such as polyoxymethylene diacetate and mixtures thereof that have recurring oxymethylene groups, which esters release formaldehyde n the presence of moisture and the effervescent couple. The effervescent couple comprises an acid member, which member acts as an acid catalyst on the compounds with recurring oxymethylene groups leading to the production of formaldehyde.
The effervescent couple useful for the purpose of this invention is a gas generating means for producing physical activity by vigorously generating carbon dioxide gas. The couple, in the presence of the probicide and an aqueous medium that enters the device, produces gaseous activity for assisting formaldehyde generated in the device to the exterior of the device. The gas generated by the couple also provides physical activity for mixing the formaldehyde throughout a solution or an enviroment for carrying out its biocidal activities. The effervescent couple comprises at least one preferably solid acidic material and a preferably solid basic material that dissolve and react in the presence of an aqueous fluid that enters the device, or they react in the presence of an aqueous fluid after the diffuse from the device to produce carbon dioxide effervescence.The couple is mixed with the probiocide in powder, crystalline or granular form and the formed composition formulated into a polymeric matrix. The acid member of the couple includs organic acid such as malic, fumaric, tartaric, itaconic, maleic, citric, adipic, succinic and mesaconic, and mixtures thereof. Also inorganic acids and acid salts such as monosodium citrate, potassium acid tartrate and potassium bitartrate can be use in the device. The basic compounds include metal carbonates and biocarbonates, such as alkali metal carbonates and bicarbonates, or alkaline earth carbonates and bicarbontes, and mixtures thereof. Exemplary materials include the alkali metals lithuim, sodium and potassium carbonates and bicarbonates, and the alkaline earth compounds magnesium and calcium carbonate or bicarbonate.
Also useful are ammonium carbonate, ammonuium sesquecarbonate. The combination of certain of these acids and bases results in a more rapid gas production or effervescence when contacted by water; in particular, either citric acid or a mixture of citric acid and tartaric acid and sodium bicarbonate give a rapid gaseous reaction that is useful for dispensing the probiocide for its intended results.
The effervescent couple is mixed with the probiocide in any an hydros or dry state preferable in substantially stoichiometrically balance to produce a combination that generates carbon dioxide. The amount of effervescent couple is about 1% to 40% of the device, more preferably 5% to 20% of the device.
The sufactants useful for the purpose of the invention include those having wetting, solubilizing and mixing properties that aid in increasing the probiocide and the generated carbon dioxide gas in effecting their beneficial results. The surfactants can be cationic, anionic or nonionic, Exemplary cationic surfactants include lauryldimethylbenzylammonium chloride, p-diisobutylphenoxy-ethoxyethyl-di- methylbenzylammonium chloride, alkyldimethylbenzylammonium chloride, laurylisoquinolinium bromide, cetylethyl-dimethylammonium bromide, stearyldimethylbenzylammonium chloride, N-soya-N-ethylmorpholinium-ethosulphate, N(acyl-colaminoformyl-methyl) pyridinium chloride, a mixture comprising alkyl (CgH19 to C,5H3,) to tolylmethyltrimethylammonium chloride and laurylisoquinolinium bromide, coamidoalkyl betaine, and N-lauryl -aminopropionic acid.Exemplary anionic surfactants include linear alkylaryl sulfonates prepared by Friedel-Crafts reaction of an olefin and benzene wherein the olefin has from 10 to 1 8 atoms, and the alkali metal salts thereof, and other anonic surfacants such as alkyllauryl sulphonate, capryl imidazoline derivatives, dioctylester of sodium sulphosuccinic acid, sodium lauryl sulphate sodium salt of alkylated aryl polyether sulpahte, triethanolmaine salt of lauryl sulphate, triethanolamine salt of alkylaryl sulphonate, and mixtures thereof.Exemplary nonionic surfactants include alkylated aryl polyether alcohol, polyethylene glycol tertdodecylthioether, fatty acid amide condensates, aromatic polyglycol ether condensates, secondary amide or lauric acid, fatty acid alkanolamine condensates, sorbitan monolaurate, sorbitan monolaurate polyoxyethylene, sorbitan mono-oleate, sorbitan monooleate polyoxyethylene derivative, mannide mono-oleate polyoxyethylene laurylether, polyoxyethylene esters of mixed resins and fatty acids, and mixtures thereof, and surfactants generically including the condensation product of a linear aliphatic alcohol having from 8 to 22 carbon atoms in its aliphatic portion and an alkylene oxide wherein the oxide constitutes from about 55 to 80% by weight of the surfactant molecule.Examples of surfactants identified by trademarks include IgepalX CO-170 a nonionic consisting essentially of nonyl phenol condensed with 10 to 11 mols of ethylene oxide; PluronicX P-65 a nonionic consisting essentially of hydrophilic polyoxyethylene groups and a hydrophobic polyoxypropylene group having an average molecular weight of 3,500 with 50% ethylene oxides; Pluronic(E) P-1 23 a nonionic with a molecular weight of about 5,650 with 30% ethylene oxide groups; DeriphatX 1 60 an ampholytic disodium N-lauryl-ss-imino-dipropionate; and the like.The amount of active surfactant agent used is an amount sufficient to achieve the intended results, usually, the amount will range from 0.01% to about 5% by weight, based on the total weight of all the components in the device.
The following examples will serve to further illustrate the present invention, but the invention is not intended to be limited thereto.
Example 1
A device is made as follows: first, 85 grams of powdered, white solid polymeric paraformaldehyde, 5 grams of citric acid and 10 grams of sodium bicarbonate are blended at a room temperature of 21"C in a dry, moisturefree enviroment for 30 minutes to yield a homogenous blend. Next, 40 grams of the blend is fed over a 5 to 1 5 minute period to a two-roll mill previously charged with ethylenevinyl acetate copolymer having a vinyl acetate content of 40%, and the milling continued for 5 to 10 minutes for thoroughly blending the blend throughout the copolymer. Then, the milled product is passed through a four-roll calendar to form a film. The film is then cut into a square shape for use in a preselected environment.
Example 2
A device is made by blending in an anhydrous enviroment 10% citric acid, 19% sodium bicarbonate, 1% Igepal surfactant and 70% paraformaldehyde to yield a homogenous blend, which is mixed with the commerically available poly(olefin), poly(ethylene) by compounding on a Barbender Plastograph with gentle heat for 7 to 14 minutes. Then, the blended mass is removed from the machine and pressed at 15,000 psi into a rectangle shaped matrix useful for controlling the presence to unwanted organisms. The device is stored in a dry package to prevent premature contact with moisture The package is comprised of two sheets of aluminum foil in faced position, defining an internal space, with the sheets joined around their peripheries in moisture proof arrangements.
Example 3
A dispensing system is prepared by mixing according to the example described above 40 grams of paraformaldehyde, 40 grams of methenamine mandelate, 5 grams of citric acid and 1 5 grams of potassium bicarboate, which is slowly added over a period of 5 to minutes with continuous milling, to a heated two-roll mill previously charged with copolymeric ethylene-ethyl acrylate. The milled formulation is removed from the mill and then extruded into a solid rod shaped system useful for sterilizing articles of manufacture.
In one embodiment, the process for control ling the presence of unwanted micro-organisms on an article of manufacture such as a barber's scissors, is carried out by submerging the article in a solution freshly formed by adding a dispensing system comprising paraformaldehyde, an efferevescant couple in a polymer support, and water. In the presence of water, the dispensing system releases paraformaldehyde that generates formaldehyde, and releases the couple that generates carbon dioxide gas which mixes the formaldehyde throughout the solution for producing the intended results.
It will be understood by those versed in the disinfectant art, that in the light of the present specification and the accompanying claims, many embodiments of the invention can be made without departing from the spirit of the invention.
Claims (14)
1. In a process for disinfecting an article of manufacture, the process comprising placing the article in the presence of a polymer containing a probiocide and an effervescent couple which probiocide on its release from the polyner produces the biocide formaldehyde and the effervescent couple generates carbon dioxide for mixing the biocide with the liquid, thereby contacting the article with the biocide for disinfecting shame.
2. The process for disinfecting the article of manufacture according to claim 1, wherein the liquid is water.
3. The process for disinfecting the article of manufacture according to claim 1, wherein the probiocide is paraformaldehyde.
4. The process for disinfecting the article of manufacturing according to claim 1, wherein the probiocide is methenamine and its salts.
5. The process for disinfecting the article of manufacture according to claim 1 wherein the polymer additionally contains a surfactant.
6. The process for disinfecting the article of manufacture according to claim 1 wherein the effervescent couple comprises an inorganic or an organic acid, and a compound capable of evolving carbon dioxide in the presence of the acid and liquid, which compound is an alkali metal carbonate, an alkali metal bicarbonate, alkaline earth carbonate or alkaline earth bicarbonate.
7. A device for controlling the presence of micro-organisms, the device comprising a polymer containing a probiocide and an effervescent couple, which probiocide on its release from the polymer produces the biocide formaldehyde and the effervescent couple on its release from the polymer is capable of evolving carbon dioxide for contacting the biocide with the organisms thereby controlling the presence of same.
8. The device for controlling the presence of micro-organisms according to claim 7 wherein the probiocide is paraformaldehyde.
9. The device for controlling the presence of micro-organisms according to claim 7 wherein the probiocide has recurring oxymethylene groups.
1 0. The device for controlling the presence of micro-organisms according to claim 7 wheren the probiocide is methenamine and its salts.
11. The device for controlling the presence of micro-organisms according to claim 7 wherein the polymer additionally contains a surfactant.
1 2. The device for controlling the presence of micro-organisms according to claim 7 wherein the effervescent couple comprises an acid and an alkali metal carbonate, an alkali metal bicarbonate, an alkaline earth carbonate or an alkaline earth bicarbonate.
1 3. A process as claimed in claim 1 and substantially as herein described with reference to and as iluustrated in the accompanying drawings and/or as described in any one of the specific examples hereinbefore set forth.
14. A device as claimed in claim 7 and substantially as herein described with reference to and as illustrated in the accompanying drawing.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26631881A | 1981-05-22 | 1981-05-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB2110089A true GB2110089A (en) | 1983-06-15 |
Family
ID=23014087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB08203683A Withdrawn GB2110089A (en) | 1981-05-22 | 1982-02-09 | Device for sterilizing articles and environment |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS57195462A (en) |
| DE (1) | DE3211280A1 (en) |
| FR (1) | FR2506159A1 (en) |
| GB (1) | GB2110089A (en) |
| IT (1) | IT1155525B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0830865A2 (en) * | 1996-09-24 | 1998-03-25 | Tomey Technology Corporation | Device and method for cleaning and disinfecting contact lens using water-absorbing solid soft material carrying disinfectant |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3503848A1 (en) * | 1985-02-05 | 1986-08-07 | Fresenius AG, 6380 Bad Homburg | Disinfectants |
| JP5924972B2 (en) * | 2012-02-16 | 2016-05-25 | 顕二 小栗 | Disinfectant |
-
1982
- 1982-02-09 GB GB08203683A patent/GB2110089A/en not_active Withdrawn
- 1982-03-25 JP JP57048086A patent/JPS57195462A/en active Pending
- 1982-03-26 DE DE19823211280 patent/DE3211280A1/en not_active Withdrawn
- 1982-04-13 IT IT67490/82A patent/IT1155525B/en active
- 1982-05-10 FR FR8208047A patent/FR2506159A1/fr not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0830865A2 (en) * | 1996-09-24 | 1998-03-25 | Tomey Technology Corporation | Device and method for cleaning and disinfecting contact lens using water-absorbing solid soft material carrying disinfectant |
| EP0830865A3 (en) * | 1996-09-24 | 2000-05-03 | Tomey Technology Corporation | Device and method for cleaning and disinfecting contact lens using water-absorbing solid soft material carrying disinfectant |
Also Published As
| Publication number | Publication date |
|---|---|
| IT1155525B (en) | 1987-01-28 |
| FR2506159A1 (en) | 1982-11-26 |
| DE3211280A1 (en) | 1982-12-09 |
| IT8267490A0 (en) | 1982-04-13 |
| JPS57195462A (en) | 1982-12-01 |
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| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |