GB2084484A - System for bicarbonate dialysate - Google Patents

System for bicarbonate dialysate

Info

Publication number
GB2084484A
GB2084484A GB8131745A GB8131745A GB2084484A GB 2084484 A GB2084484 A GB 2084484A GB 8131745 A GB8131745 A GB 8131745A GB 8131745 A GB8131745 A GB 8131745A GB 2084484 A GB2084484 A GB 2084484A
Authority
GB
United Kingdom
Prior art keywords
molar
ion
concentration
acid
sodium carbonate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB8131745A
Other versions
GB2084484B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/209,742 external-priority patent/US4326955A/en
Application filed by Individual filed Critical Individual
Publication of GB2084484A publication Critical patent/GB2084484A/en
Application granted granted Critical
Publication of GB2084484B publication Critical patent/GB2084484B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1666—Apparatus for preparing dialysates by dissolving solids

Abstract

A dialysate solution containing bicarbonate ion in which the bicarbonate ion is generated in a flowing stream prior to dialysis by combining an aqueous sodium carbonate-containing stream produced from a bacteriostatic concentrate with an aqueous stream containing hydrochloric acid, acetic acid or a mixture of these acids in two stages with an excess of acid in the first stage. The bicarbonate ion can be generated using a proportioning system in which the conductivity as well as the hydrogen ion activity of the resulting bicarbonate-containing dialysate is monitored. The acid can be provided in a unit dosage form of aqueous concentrate additionally containing chloride ion in a concentration of about 3.5 Molar to about 4.7 Molar, sodium ion in a concentration of about 1.9 Molar to about 2.7 Molar, and dextrose in a concentration of about 0 Molar to about 0.4 Molar. Additionally, the acid concentrate may contain acetate group in a concentration of up to about 0.525 Molar, calcium ion in a concentration of up to about 0.125 Molar, potassium ion in a concentration of up to about 0.14 Molar, and magnesium ion in a concentration of up to about 0.09 Molar. The sodium carbonate containing stream can be generated by diluting an aqueous concentrate comprising at least about 20 grams of sodium carbonate, calculated as anhydrous sodium carbonate, per liter of solution.
GB8131745A 1980-05-09 1981-04-21 System for bicarbonate dialysate Expired GB2084484B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14820080A 1980-05-09 1980-05-09
US06/209,742 US4326955A (en) 1979-06-14 1980-11-24 Hemodialysis with sodium bicarbonate dialysate prepared in plural stages

Publications (2)

Publication Number Publication Date
GB2084484A true GB2084484A (en) 1982-04-15
GB2084484B GB2084484B (en) 1984-08-22

Family

ID=26845634

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8131745A Expired GB2084484B (en) 1980-05-09 1981-04-21 System for bicarbonate dialysate

Country Status (8)

Country Link
EP (1) EP0051659A4 (en)
JP (1) JPS57500565A (en)
AU (1) AU7176881A (en)
CA (1) CA1166966A (en)
GB (1) GB2084484B (en)
IT (1) IT1170954B (en)
SE (1) SE8200109L (en)
WO (1) WO1981003180A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743191B1 (en) 1999-04-26 2004-06-01 Edwards Lifesciences Ag Substitution infusion fluid and citrate anticoagulation
US7186420B2 (en) 1999-04-26 2007-03-06 Edwards Lifesciences Corporation Multi-part substitution infusion fluids and matching anticoagulants
US8105258B2 (en) 1999-04-26 2012-01-31 Baxter International Inc. Citrate anticoagulation system for extracorporeal blood treatments

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4489535A (en) * 1980-10-02 1984-12-25 Veltman Preston Leonard Materials and method for preparing dialysis solutions containing bicarbonate ions
US5092838A (en) * 1989-11-30 1992-03-03 Baxter International Inc. Histidine buffered peritoneal dialysis solution
AU627309B2 (en) † 1989-05-26 1992-08-20 Terumo Kabushiki Kaisha Preparation for blood dialysis and method for production thereof
DE4122754A1 (en) * 1991-07-10 1993-01-21 Martin Prof Dr Med Vlaho Substitute soln. for haemo-filtration in dialysing processes - contains sodium, potassium, calcium, magnesium, chloride ions, glucose, lactate and bi:carbonate, esp. for patients with weakened liver function
DE4211455C1 (en) * 1992-04-06 1993-12-16 Schael Wilfried Continuous prepn. of blod dialysis fluids - uses precise concns. of aq. concentrates tailored to patient's requirements
US5383324A (en) * 1993-04-23 1995-01-24 Baxter International Inc. Method for manufacturing and storing stable bicarbonate solutions
CA2211848C (en) * 1997-07-28 2002-06-11 Joseph E. Dadson Peritoneal dialysis apparatus
JP5803543B2 (en) * 2011-10-11 2015-11-04 ニプロ株式会社 Dialysis fluid preparation device diagnostic method and dialysis fluid preparation device
KR101458174B1 (en) 2012-08-31 2014-11-04 김영기 produce method to produce hemo dialysate
JP5840248B2 (en) * 2014-03-19 2016-01-06 株式会社日本トリム Dialysate production equipment
DE102016009442A1 (en) * 2016-08-03 2018-02-08 Fresenius Medical Care Deutschland Gmbh Method for monitoring the bicarbonate content and the sodium content of a dialysis solution
WO2023144901A1 (en) * 2022-01-26 2023-08-03 ニプロ株式会社 Method for adjusting dialysate
US11925703B1 (en) 2022-07-29 2024-03-12 Xellia Pharmaceuticals Aps Liquid composition comprising glucose

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3352779A (en) * 1965-10-23 1967-11-14 Sweden Freezer Mfg Co Hemodialysis system
US3962075A (en) * 1973-09-10 1976-06-08 Tri-Flo Research Laboratories, Ltd. Hemo dialyzer employing two dialysate solutions
US4202760A (en) * 1978-07-24 1980-05-13 Cordis Dow Corp. Apparatus and method for preparation of a hemodialysis solution optionally containing bicarbonate

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743191B1 (en) 1999-04-26 2004-06-01 Edwards Lifesciences Ag Substitution infusion fluid and citrate anticoagulation
US7186420B2 (en) 1999-04-26 2007-03-06 Edwards Lifesciences Corporation Multi-part substitution infusion fluids and matching anticoagulants
US7758900B2 (en) 1999-04-26 2010-07-20 Baxter International Inc. Multi-part substitution infusion fluids and matching anticoagulants
US8105258B2 (en) 1999-04-26 2012-01-31 Baxter International Inc. Citrate anticoagulation system for extracorporeal blood treatments
US8158157B2 (en) 1999-04-26 2012-04-17 Baxter International Inc. Multi-part substitution infusion fluids and matching anticoagulants
US8529486B2 (en) 1999-04-26 2013-09-10 Baxter International Inc. Citrate anticoagulation system for extracorporeal blood treatments
US8795517B2 (en) 1999-04-26 2014-08-05 Nikkiso Co., Ltd. Machine readable medium embodying instructions for citrate anticoagulation system for extracorporeal blood treatments

Also Published As

Publication number Publication date
EP0051659A1 (en) 1982-05-19
AU7176881A (en) 1981-11-26
GB2084484B (en) 1984-08-22
EP0051659A4 (en) 1982-11-08
CA1166966A (en) 1984-05-08
IT1170954B (en) 1987-06-03
IT8148421A0 (en) 1981-05-08
JPS57500565A (en) 1982-04-01
WO1981003180A1 (en) 1981-11-12
SE8200109L (en) 1982-01-11

Similar Documents

Publication Publication Date Title
GB2084484A (en) System for bicarbonate dialysate
ES8502873A1 (en) Dialysis solutions containing bicarbonate ions.
MY112428A (en) Peritoneal dialysis solutions containing maltodextrins and amino acids.
DE3063088D1 (en) Method of forming an aqueous dialysis solution
IL76119A (en) Device for initiating reperfusion treatment when heart attack symptoms are present
BR9506021A (en) Peritoneal dialysis solution and process to correct metabolic acidosis
DE19748290B8 (en) Solution for peritoneal dialysis
ES2149793T3 (en) PROCEDURE FOR THE PREPARATION OF BICARBONATED DIALYZING LIQUID FOR HEMODIALYSIS.
IL86859A (en) Aqueous cathartic solution containing inorganic salts
ATE279930T1 (en) AQUEOUS ALKALINE METAL BICARBONATE SOLUTIONS FOR THE TREATMENT OF OSTEOARTHROSIS
AU8111482A (en) Zinc insulin stabilized with calcium or magnesium salts
DE3464849D1 (en) Stable, aqueous, acidic solution of cis-platinum, suitable for injection
LV5660A3 (en) Satisfaction with the acquisition of an antiviral agent
GB1304595A (en)
ES8203850A1 (en) [(1-Benzyl-1H-indazol-3-yl)oxy] acetic acid salt with L. lysine
JPS5762218A (en) Ophthalmic solution
HK1034896A1 (en) Ionic aqueous composition containing levomenthol
AU7568298A (en) Purification of polyphosphazene polyacids
JPS5756422A (en) Dialytic solution for artificial kidney
JPS5780328A (en) Preparation of stable pharmaceutical preparation
JPS5448745A (en) Preparation of n-2-fluorenesulfonylamino acid
JPS5285061A (en) Removal of fluorine ions in solution containing conc. silicic acid
DE3788698T2 (en) Process for the preparation of salts of mercaptoethylsulfonic acid.
GB1171244A (en) Purification of Flavine Adenine Dinucleotide
SU911939A1 (en) SOLUTION FOR TREATMENT OF THE FORWARDING ZONE PLASTE

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee