GB2080310B - Tripeptide inhibitors of angiotensin-converting enzyme - Google Patents

Tripeptide inhibitors of angiotensin-converting enzyme

Info

Publication number
GB2080310B
GB2080310B GB8117919A GB8117919A GB2080310B GB 2080310 B GB2080310 B GB 2080310B GB 8117919 A GB8117919 A GB 8117919A GB 8117919 A GB8117919 A GB 8117919A GB 2080310 B GB2080310 B GB 2080310B
Authority
GB
United Kingdom
Prior art keywords
angiotensin
converting enzyme
tripeptide inhibitors
tripeptide
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8117919A
Other languages
English (en)
Other versions
GB2080310A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB2080310A publication Critical patent/GB2080310A/en
Application granted granted Critical
Publication of GB2080310B publication Critical patent/GB2080310B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
GB8117919A 1980-07-24 1981-06-11 Tripeptide inhibitors of angiotensin-converting enzyme Expired GB2080310B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/171,772 US4293481A (en) 1980-07-24 1980-07-24 Tripeptide inhibitors of angiotensin-converting enzyme

Publications (2)

Publication Number Publication Date
GB2080310A GB2080310A (en) 1982-02-03
GB2080310B true GB2080310B (en) 1983-11-16

Family

ID=22625069

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8117919A Expired GB2080310B (en) 1980-07-24 1981-06-11 Tripeptide inhibitors of angiotensin-converting enzyme

Country Status (7)

Country Link
US (1) US4293481A (cg-RX-API-DMAC7.html)
JP (1) JPS5753447A (cg-RX-API-DMAC7.html)
CA (1) CA1187870A (cg-RX-API-DMAC7.html)
DE (1) DE3129297A1 (cg-RX-API-DMAC7.html)
FR (1) FR2487341A1 (cg-RX-API-DMAC7.html)
GB (1) GB2080310B (cg-RX-API-DMAC7.html)
IT (1) IT1211069B (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356182A (en) * 1979-10-22 1982-10-26 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines
US4456761A (en) * 1981-02-02 1984-06-26 E. R. Squibb & Sons, Inc. 4-Substituted dehydroprolines
US4746676A (en) * 1984-09-12 1988-05-24 Rorer Pharmaceutical Corporation Carboxyalkyl dipeptide compounds
FR2578544A1 (en) * 1985-03-11 1986-09-12 Usv Pharma Corp Antihypertension spirocyclic compounds
FR2585709B1 (fr) * 1985-08-05 1987-10-02 Adir Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1874128A1 (en) * 2005-04-28 2008-01-09 Hindustan Unilever Limited Peptides having an ace inhibiting effect

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191753A (en) * 1978-11-06 1980-03-04 University Of Miami Anti-hypertensive peptide analogs

Also Published As

Publication number Publication date
JPS5753447A (en) 1982-03-30
IT8122566A0 (it) 1981-06-25
FR2487341B1 (cg-RX-API-DMAC7.html) 1984-08-17
DE3129297A1 (de) 1982-05-13
US4293481A (en) 1981-10-06
GB2080310A (en) 1982-02-03
IT1211069B (it) 1989-09-29
FR2487341A1 (fr) 1982-01-29
CA1187870A (en) 1985-05-28

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee