GB2066256A - Intermediate compounds for preparation of morphine derivatives - Google Patents

Intermediate compounds for preparation of morphine derivatives

Info

Publication number
GB2066256A
GB2066256A GB8107295A GB8107295A GB2066256A GB 2066256 A GB2066256 A GB 2066256A GB 8107295 A GB8107295 A GB 8107295A GB 8107295 A GB8107295 A GB 8107295A GB 2066256 A GB2066256 A GB 2066256A
Authority
GB
United Kingdom
Prior art keywords
preparation
intermediate compounds
morphine derivatives
hydroxynormorphones
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB8107295A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of GB2066256A publication Critical patent/GB2066256A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB8107295A 1979-08-09 1980-08-07 Intermediate compounds for preparation of morphine derivatives Withdrawn GB2066256A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6527579A 1979-08-09 1979-08-09

Publications (1)

Publication Number Publication Date
GB2066256A true GB2066256A (en) 1981-07-08

Family

ID=22061564

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8107295A Withdrawn GB2066256A (en) 1979-08-09 1980-08-07 Intermediate compounds for preparation of morphine derivatives

Country Status (16)

Country Link
JP (1) JPS56501010A (enExample)
AU (1) AU6116580A (enExample)
BE (1) BE884671A (enExample)
DD (1) DD154541A5 (enExample)
DK (1) DK151781A (enExample)
ES (1) ES494122A0 (enExample)
FI (1) FI802479A7 (enExample)
FR (1) FR2465735A1 (enExample)
GB (1) GB2066256A (enExample)
IL (1) IL60783A0 (enExample)
IT (1) IT8068267A0 (enExample)
NL (1) NL8020319A (enExample)
NO (1) NO802139L (enExample)
PL (1) PL226162A1 (enExample)
SE (1) SE8102214L (enExample)
WO (1) WO1981000409A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795813A (en) * 1981-08-17 1989-01-03 The Florida Board Of Regents On Behalf Of The Florida State University Synthesis of derivatives of codeine and other 3-O-alkylmorphines
US5668285A (en) * 1986-10-31 1997-09-16 The United States Of America As Represented By The Department Of Health And Human Services Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
CA2067200C (en) * 1989-10-16 1998-06-30 Kenner C. Rice Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA913077A (en) * 1972-10-24 J. Pachter Irwin Process of preparing n-substituted 14-hydroxydihydronormorphines
US3249616A (en) * 1966-05-03 Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof
US2772270A (en) * 1954-10-21 1956-11-27 M J Lewenstein 14-hydroxymorphinone and 8, 14-dihydroxydihydromorphinone
US2806033A (en) * 1955-08-03 1957-09-10 Lewenstein Morphine derivative
BE638369A (enExample) * 1962-10-10
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
NL7106612A (en) * 1971-05-13 1972-11-15 N-cycloalkylalkyl-14-hydroxy-dihydronormorphines - - by o-demethylation of 14-methoxy cpds
US3775414A (en) * 1972-05-10 1973-11-27 Bristol Myers Co Process for the preparation of 14-hydroxymorphinan derivatives
US4161597A (en) * 1976-12-20 1979-07-17 Research Corporation N-alkyl-14-hydroxymorphinans and derivatives

Also Published As

Publication number Publication date
JPS56501010A (enExample) 1981-07-23
NL8020319A (nl) 1981-07-01
BE884671A (fr) 1980-12-01
ES8104296A1 (es) 1981-04-16
WO1981000409A1 (en) 1981-02-19
PL226162A1 (enExample) 1981-04-24
AU6116580A (en) 1981-02-12
ES494122A0 (es) 1981-04-16
FR2465735A1 (fr) 1981-03-27
IT8068267A0 (it) 1980-08-07
DD154541A5 (de) 1982-03-31
DK151781A (da) 1981-04-03
SE8102214L (sv) 1981-04-07
FI802479A7 (fi) 1981-01-01
IL60783A0 (en) 1980-10-26
NO802139L (no) 1981-02-10

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)