GB2046734B - 7-(-oximino-pyrazolyl(-acetamido)-cephen derivatives - Google Patents

7-(-oximino-pyrazolyl(-acetamido)-cephen derivatives

Info

Publication number
GB2046734B
GB2046734B GB8004696A GB8004696A GB2046734B GB 2046734 B GB2046734 B GB 2046734B GB 8004696 A GB8004696 A GB 8004696A GB 8004696 A GB8004696 A GB 8004696A GB 2046734 B GB2046734 B GB 2046734B
Authority
GB
United Kingdom
Prior art keywords
cephen
oximino
acetamido
pyrazolyl
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8004696A
Other languages
English (en)
Other versions
GB2046734A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH154579A external-priority patent/CH641810A5/de
Priority claimed from CH17480A external-priority patent/CH645378A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB2046734A publication Critical patent/GB2046734A/en
Application granted granted Critical
Publication of GB2046734B publication Critical patent/GB2046734B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • C07D231/40Acylated on said nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB8004696A 1979-02-16 1980-02-12 7-(-oximino-pyrazolyl(-acetamido)-cephen derivatives Expired GB2046734B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH154579A CH641810A5 (en) 1979-02-16 1979-02-16 Acetamidocephalosporanic acid derivatives, process for their preparation and pharmaceutical forms which contain them
CH17480A CH645378A5 (en) 1980-01-10 1980-01-10 Acetamidocephalosporanic acid derivatives, process for their preparation and pharmaceutical forms which contain them

Publications (2)

Publication Number Publication Date
GB2046734A GB2046734A (en) 1980-11-19
GB2046734B true GB2046734B (en) 1983-09-01

Family

ID=25683752

Family Applications (2)

Application Number Title Priority Date Filing Date
GB8004696A Expired GB2046734B (en) 1979-02-16 1980-02-12 7-(-oximino-pyrazolyl(-acetamido)-cephen derivatives
GB08309730A Expired GB2117774B (en) 1979-02-16 1983-04-11 Oximinoacetic acid derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB08309730A Expired GB2117774B (en) 1979-02-16 1983-04-11 Oximinoacetic acid derivatives

Country Status (19)

Country Link
US (1) US4477448A (enExample)
AT (1) AT374806B (enExample)
CA (1) CA1161032A (enExample)
DE (1) DE3005012A1 (enExample)
DK (1) DK53780A (enExample)
ES (2) ES8102134A1 (enExample)
FI (1) FI800381A7 (enExample)
FR (1) FR2449093A1 (enExample)
GB (2) GB2046734B (enExample)
IE (1) IE49395B1 (enExample)
IL (1) IL59391A (enExample)
IT (1) IT8047922A0 (enExample)
MY (1) MY8500128A (enExample)
NL (1) NL8000894A (enExample)
NZ (1) NZ192873A (enExample)
PH (1) PH17926A (enExample)
PT (1) PT70834A (enExample)
SE (2) SE8000982L (enExample)
YU (1) YU40280A (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0037380B1 (en) * 1980-03-28 1984-09-12 BIOCHEMIE Gesellschaft m.b.H. New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
CH648038A5 (de) * 1981-01-19 1985-02-28 Sandoz Ag 7-((carboxymethoxyimino)-1h-pyrazol-3-yl-acetyl)amino-3-desacetoxy-3-(1-methyl-1h-tetrazol-5-yl-thio)cephalosporansaeure und salze, verfahren zur herstellung und verwendung.
GB2125033B (en) * 1982-07-23 1985-08-29 Servipharm Ltd Cephalosporins
US4698338A (en) * 1986-02-19 1987-10-06 Eli Lilly And Company 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins
US5688964A (en) * 1996-02-13 1997-11-18 Eastman Kodak Company Process for preparing a acylhyrazino pyrazole derivative
KR100770419B1 (ko) * 1999-09-24 2007-10-26 니혼노야쿠가부시키가이샤 살충, 살진드기제
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白(rap)-缀合物对肝病症的治疗
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024137A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins

Also Published As

Publication number Publication date
ES488651A0 (es) 1980-12-16
IE49395B1 (en) 1985-10-02
GB2117774B (en) 1984-03-21
GB2046734A (en) 1980-11-19
YU40280A (en) 1983-06-30
SE8500589D0 (sv) 1985-02-08
IL59391A (en) 1983-05-15
MY8500128A (en) 1985-12-31
FR2449093A1 (fr) 1980-09-12
ES497002A0 (es) 1982-04-01
FI800381A7 (fi) 1981-01-01
ES8102134A1 (es) 1980-12-16
DK53780A (da) 1980-08-17
GB2117774A (en) 1983-10-19
SE8000982L (sv) 1980-08-17
PH17926A (en) 1985-01-31
GB8309730D0 (en) 1983-05-18
ATA78780A (de) 1983-10-15
DE3005012A1 (de) 1980-11-27
FR2449093B1 (enExample) 1983-07-29
ES8203848A1 (es) 1982-04-01
IE800284L (en) 1980-08-16
NZ192873A (en) 1984-07-31
AT374806B (de) 1984-06-12
PT70834A (en) 1980-03-01
IL59391A0 (en) 1980-05-30
US4477448A (en) 1984-10-16
CA1161032A (en) 1984-01-24
IT8047922A0 (it) 1980-02-15
NL8000894A (nl) 1980-08-19

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee