GB2021102A - Glycol compounds for lowering the lipid content - Google Patents

Glycol compounds for lowering the lipid content

Info

Publication number
GB2021102A
GB2021102A GB7914395A GB7914395A GB2021102A GB 2021102 A GB2021102 A GB 2021102A GB 7914395 A GB7914395 A GB 7914395A GB 7914395 A GB7914395 A GB 7914395A GB 2021102 A GB2021102 A GB 2021102A
Authority
GB
United Kingdom
Prior art keywords
formula
hydrogen
rest
alkyl
glycol compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7914395A
Other versions
GB2021102B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siegfried AG
Original Assignee
Siegfried AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siegfried AG filed Critical Siegfried AG
Publication of GB2021102A publication Critical patent/GB2021102A/en
Application granted granted Critical
Publication of GB2021102B publication Critical patent/GB2021102B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

New glycol compounds of formula (1). (FORMULA) wherein, R<s1>s is hydrogen, alkyl with 1 to 4 atoms of C or aryl R<s2>s is hydrogen or alkyl with 1 to 4 atoms of C R<s3>s is hydrogen or a group of formula (FORMULA) where Z is an alkyl rest, an aryl rest eventually sustituted or a heterocyclic rest, R<s4>s is a rest of formula (FORMULA) where R<s5>s is hydrogen or a chlorine atom or a methyl group, have a significant lowering action on the blood grade of cholesterol and of triglycerides. The preparation of these new compounds is described either by reduction of the corresponding acids, or by reaction of a phenol of formula (FORMULA) with an alcohol of formula (FORMULA) possibly followed by an esterification.
GB7914395A 1977-08-29 1978-08-28 Glycol compounds for lowering the lipid content Expired GB2021102B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1049877A CH630879A5 (en) 1977-08-29 1977-08-29 METHOD FOR PRODUCING LIPID-REDUCING ALKYLENE GLYCOLE DERIVATIVES.

Publications (2)

Publication Number Publication Date
GB2021102A true GB2021102A (en) 1979-11-28
GB2021102B GB2021102B (en) 1982-04-07

Family

ID=4363862

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7914395A Expired GB2021102B (en) 1977-08-29 1978-08-28 Glycol compounds for lowering the lipid content

Country Status (7)

Country Link
EP (1) EP0007347B1 (en)
JP (1) JPS5446755A (en)
CH (2) CH630879A5 (en)
DE (1) DE2856994D2 (en)
GB (1) GB2021102B (en)
IT (1) IT1210459B (en)
WO (1) WO1979000116A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17096A (en) * 1980-02-07 1984-05-29 Richardson Merrell Inc Anti-rhinovirus agents
JPS57102866A (en) * 1980-12-19 1982-06-26 Kyorin Pharmaceut Co Ltd Nicotinic acid derivative and its preparation
DE4327365A1 (en) * 1993-08-14 1995-02-16 Boehringer Mannheim Gmbh Use of phenols and phenol derivatives as drugs with a fibrinogen-lowering effect

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1481862A (en) * 1974-01-23 1977-08-03 Ciba Geigy Ag Dyeing of hydrophobic fibres

Also Published As

Publication number Publication date
GB2021102B (en) 1982-04-07
CH630879A5 (en) 1982-07-15
IT7868953A0 (en) 1978-08-23
CH635055A5 (en) 1983-03-15
EP0007347B1 (en) 1981-12-30
EP0007347A1 (en) 1980-02-06
JPS5446755A (en) 1979-04-12
DE2856994D2 (en) 1980-11-20
IT1210459B (en) 1989-09-14
WO1979000116A1 (en) 1979-03-08

Similar Documents

Publication Publication Date Title
IE801684L (en) Triiodo-isophthalic acid derivatives
YU224679A (en) Process for obtaining 9-hydroxyalkyl hypoxanthine
JPS5278848A (en) Preparation of novel propionic acid ester derivatives
DE3062452D1 (en) Branched fatty acid cholesterol ester and a cosmetic composition containing the same
ATE38979T1 (en) PRODUCTION PROCESS OF FLUORINATED ALKYL(METHYL)ACRYLATES.
FR2452483A1 (en) ALCENYLPHENYLMALEIMIDES DERIVATIVES, THEIR LINEAR DIMERES AND THEIR PREPARATION PROCESS
IE43627L (en) Phenoxyalkylcarboxylic acids and esters
IE43637L (en) Phenoxyalkylcarboxylic acid derivatives
GB2021102A (en) Glycol compounds for lowering the lipid content
IE780778L (en) 3-pyridazinones.
KR830001292A (en) Preparation of 3-Exomethylene Cepam Sulfoxides
KR830007693A (en) Improved method for preparing 7-amino cefem compound
ES486377A1 (en) Process for the preparation of 5-mercapto-1,2,3-triazoles
SE8004622L (en) ACYLAMINOBENSOESYRADERIVAT
DE3060945D1 (en) Silyl-benzimidazole-carbamic acid esters, process for their preparation and their use as fungicides
GB2001974A (en) Vincinic acid derivatives and process for the preparation thereof
GB1521458A (en) Hypolipidemic rho-aminobenzoic acids
FR2485000B1 (en)
ES459954A1 (en) Derivatives of cyclopropane
JPS5782381A (en) Beta-benzoylglycidic acid derivative
IE800978L (en) Esters of 2-(6-methoxy-2-naphthyl)-1-propanol
ES465758A1 (en) Procedure for obtaining monoester from p-chlorophenoxy-isobutirico acid with 2,6-pyridindimethanol, new pharmacy with hypocolesteramient action. (Machine-translation by Google Translate, not legally binding)
ES479710A1 (en) Manufacture of chromonee22carboxyic acid
JPS52133960A (en) 2-cyano-3-methyl-3-(6-methoxy-2-naphthyl)-glycidic acid and method of preparing the same
JPS52102274A (en) 8-azaprostanic acid derivatives

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee