GB202019165D0 - Replication-defective redcombinant H9N2 avian influenza virus expressing HA of H5 subtype - Google Patents

Replication-defective redcombinant H9N2 avian influenza virus expressing HA of H5 subtype

Info

Publication number
GB202019165D0
GB202019165D0 GBGB2019165.6A GB202019165A GB202019165D0 GB 202019165 D0 GB202019165 D0 GB 202019165D0 GB 202019165 A GB202019165 A GB 202019165A GB 202019165 D0 GB202019165 D0 GB 202019165D0
Authority
GB
United Kingdom
Prior art keywords
redcombinant
subtype
replication
defective
influenza virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GBGB2019165.6A
Other versions
GB2589230B (en
GB2589230A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qingdao Agricultural University
Original Assignee
Qingdao Agricultural University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qingdao Agricultural University filed Critical Qingdao Agricultural University
Publication of GB202019165D0 publication Critical patent/GB202019165D0/en
Publication of GB2589230A publication Critical patent/GB2589230A/en
Application granted granted Critical
Publication of GB2589230B publication Critical patent/GB2589230B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16061—Methods of inactivation or attenuation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB2019165.6A 2018-09-14 2018-11-07 Replication-defective recombinant H9N2 avian influenza virus expressing HA of H5 subtype Expired - Fee Related GB2589230B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201811076526.2A CN109136199B (en) 2018-09-14 2018-09-14 Replication-defective recombinant H9N2 avian influenza virus expressing H5 subtype HA
PCT/CN2018/114270 WO2020052035A1 (en) 2018-09-14 2018-11-07 Replication-defective recombinant h9n2 avian influenza virus expressing ha of h5 subtype

Publications (3)

Publication Number Publication Date
GB202019165D0 true GB202019165D0 (en) 2021-01-20
GB2589230A GB2589230A (en) 2021-05-26
GB2589230B GB2589230B (en) 2023-01-04

Family

ID=64825552

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2019165.6A Expired - Fee Related GB2589230B (en) 2018-09-14 2018-11-07 Replication-defective recombinant H9N2 avian influenza virus expressing HA of H5 subtype

Country Status (3)

Country Link
CN (1) CN109136199B (en)
GB (1) GB2589230B (en)
WO (1) WO2020052035A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109097341B (en) * 2018-08-28 2021-09-24 青岛农业大学 Replication-defective recombinant influenza virus capable of simultaneously expressing HA and HEF
CN114836390B (en) * 2022-06-13 2023-05-02 华南农业大学 H9N2 subtype avian influenza virus MDCK cell cold-adaptation attenuated live vaccine strain and application thereof
CN115998854A (en) * 2023-01-30 2023-04-25 南京市第二医院 Application of non-coding region of influenza virus genes in preparation of mRNA vaccine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8992939B2 (en) * 2003-07-11 2015-03-31 Novavax, Inc. Highly efficient influenza matrix (M1) proteins
CN101193655A (en) * 2005-04-11 2008-06-04 美国政府健康及人类服务部，疾病控制和预防中心 Vaccine against pandemic strains of influenza viruses
CN100467591C (en) * 2005-06-21 2009-03-11 中国农业科学院哈尔滨兽医研究所 Recombinant fowl influenza virus strain, its preparation method and the vaccine obtained therefrom
CN1313605C (en) * 2005-07-08 2007-05-02 扬州大学 Gene recombinant fowl influenza virus D3/F-R2/6 and its construction method
US9511134B2 (en) * 2006-05-18 2016-12-06 Epimmune Inc. Inducing immune responses to influenza virus using polypeptide and nucleic acid compositions
CN102526718B (en) * 2010-12-30 2013-12-18 华中农业大学 Recombinant H5N1 (Hemagglutinin 5 Neuraminidase 1) avian influenza virus cell vaccine and application thereof
CN103497967A (en) * 2013-08-26 2014-01-08 华中农业大学 Construction method and use of duck enteritis virus bacterial artificial chromosome
CN104404005A (en) * 2014-12-22 2015-03-11 天津瑞普生物技术股份有限公司 Preparation method of avian influenza virus HA gene recombinant adenovirus
CN107353328A (en) * 2017-08-23 2017-11-17 上海市动物疫病预防控制中心 A kind of H9N2 subtype avian influenza virus sample particles of restructuring and its production and use

Also Published As

Publication number Publication date
GB2589230B (en) 2023-01-04
GB2589230A (en) 2021-05-26
WO2020052035A1 (en) 2020-03-19
CN109136199A (en) 2019-01-04
CN109136199B (en) 2020-02-07

Similar Documents

Publication Publication Date Title
EP3609534A4 (en) Broad spectrum influenza virus vaccine
MA46904A (en) VIRAL ADMINISTRATION OF NEO-ANTIGENS
CL2016002413A1 (en) Hemagglutinin antibodies against influenza b virus and methods of use
EP3490531A4 (en) Adeno-associated virus virions with variant capsid and methods of use thereof
ZA201700165B (en) Influenza virus vaccines and uses thereof
EP3247389A4 (en) Influenza virus vaccination regimens
EP3471767A4 (en) Influenza virus hemagglutinin proteins and uses thereof
GB202019165D0 (en) Replication-defective redcombinant H9N2 avian influenza virus expressing HA of H5 subtype
IL266148A (en) Recombinant vectors expressing antigens of avian influenza virus and uses thereof
SG11201610443WA (en) Influenza virus vaccines and uses thereof
ZA202004538B (en) Influenza virus vaccines and uses thereof
MA40773A (en) INFLUENZA A VIRUS VARIANTS
IL279729A (en) Influenza virus hemagglutinin mutants
EP3699186A4 (en) Mutant of h3n2 subtype influenza virus hemagglutinin protein and use thereof
PT3866778T (en) Combinations of inhibitors of influenza virus replication
EP3353192A4 (en) Design and characterization of influenza vaccines
EP3672630A4 (en) Production of flu vaccine inmyceliophthora thermophila
SG11202006379UA (en) Human antibodies to influenza hemagglutinin
FI20155554A (en) Method for the preparation of a library of derivatives of the SH3 domain of recombinant nephrocystin (NPHP1)
IL255348B (en) Modified h7 hemagluttinin glycoprotein of the influenza a/shanghai/2/2013 h7 sequence
EP3876983A4 (en) Immunogenic composition against avian influenza virus h5 subtype
PL3800257T3 (en) Pan-genotypic agents against influenza virus and methods of using the same
KR101921384B9 (en) Antigen composition against orthomyxoviruses comprising influenza virus surface protein hemagglutinin monomer
ZA201904164B (en) Preparation method and application of recombinant oncolytic influenza virus
FI20146177A (en) Process for the preparation of catalytic nano coating

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20230404