GB202018503D0 - Analyte detection method employing concatamers - Google Patents

Analyte detection method employing concatamers

Info

Publication number
GB202018503D0
GB202018503D0 GBGB2018503.9A GB202018503A GB202018503D0 GB 202018503 D0 GB202018503 D0 GB 202018503D0 GB 202018503 A GB202018503 A GB 202018503A GB 202018503 D0 GB202018503 D0 GB 202018503D0
Authority
GB
United Kingdom
Prior art keywords
concatamers
detection method
analyte detection
method employing
employing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2018503.9A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olink Proteomics AB
Original Assignee
Olink Proteomics AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olink Proteomics AB filed Critical Olink Proteomics AB
Priority to GBGB2018503.9A priority Critical patent/GB202018503D0/en
Publication of GB202018503D0 publication Critical patent/GB202018503D0/en
Priority to AU2021388789A priority patent/AU2021388789A1/en
Priority to CA3199169A priority patent/CA3199169A1/en
Priority to EP21814800.5A priority patent/EP4251762A1/en
Priority to US17/534,548 priority patent/US20220162589A1/en
Priority to KR1020237018806A priority patent/KR20230112647A/ko
Priority to JP2023554083A priority patent/JP2023550568A/ja
Priority to IL303093A priority patent/IL303093A/en
Priority to PCT/EP2021/082775 priority patent/WO2022112300A1/en
Priority to CN202180087675.2A priority patent/CN116745433A/zh
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/151—Modifications characterised by repeat or repeated sequences, e.g. VNTR, microsatellite, concatemer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/191—Modifications characterised by incorporating an adaptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/122—Massive parallel sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
GBGB2018503.9A 2020-11-25 2020-11-25 Analyte detection method employing concatamers Ceased GB202018503D0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
GBGB2018503.9A GB202018503D0 (en) 2020-11-25 2020-11-25 Analyte detection method employing concatamers
CN202180087675.2A CN116745433A (zh) 2020-11-25 2021-11-24 采用多联体的分析物检测方法
US17/534,548 US20220162589A1 (en) 2020-11-25 2021-11-24 Analyte Detection Method Employing Concatemers
CA3199169A CA3199169A1 (en) 2020-11-25 2021-11-24 Analyte detection method employing concatemers
EP21814800.5A EP4251762A1 (en) 2020-11-25 2021-11-24 Analyte detection method employing concatemers
AU2021388789A AU2021388789A1 (en) 2020-11-25 2021-11-24 Analyte detection method employing concatemers
KR1020237018806A KR20230112647A (ko) 2020-11-25 2021-11-24 콘카티머를 사용한 분석물 검출 방법
JP2023554083A JP2023550568A (ja) 2020-11-25 2021-11-24 コンカテマーを用いた分析物検出方法
IL303093A IL303093A (en) 2020-11-25 2021-11-24 Analyte detection method employing concatemers
PCT/EP2021/082775 WO2022112300A1 (en) 2020-11-25 2021-11-24 Analyte detection method employing concatemers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2018503.9A GB202018503D0 (en) 2020-11-25 2020-11-25 Analyte detection method employing concatamers

Publications (1)

Publication Number Publication Date
GB202018503D0 true GB202018503D0 (en) 2021-01-06

Family

ID=74046815

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2018503.9A Ceased GB202018503D0 (en) 2020-11-25 2020-11-25 Analyte detection method employing concatamers

Country Status (10)

Country Link
US (1) US20220162589A1 (https=)
EP (1) EP4251762A1 (https=)
JP (1) JP2023550568A (https=)
KR (1) KR20230112647A (https=)
CN (1) CN116745433A (https=)
AU (1) AU2021388789A1 (https=)
CA (1) CA3199169A1 (https=)
GB (1) GB202018503D0 (https=)
IL (1) IL303093A (https=)
WO (1) WO2022112300A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4615996A1 (en) 2022-11-11 2025-09-17 Olink Proteomics AB Library of proximity probes and method of use
WO2025012398A1 (en) 2023-07-11 2025-01-16 Olink Proteomics Ab Dried reagents
WO2025012226A1 (en) 2023-07-12 2025-01-16 Olink Proteomics Ab Method, components and software for detecting a systematic error in a protein detection system
WO2025031642A1 (en) 2023-08-07 2025-02-13 Olink Proteomics Ab A method for determining run errors for an analysis-method for quantifying a plurality of analytes in a plurality of biological samples
WO2025252658A1 (en) 2024-06-03 2025-12-11 Olink Proteomics Ab New product and method
WO2025262178A1 (en) 2024-06-18 2025-12-26 Olink Proteomics Ab System and method for detecting analytes in a sample

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001061037A1 (en) 2000-02-18 2001-08-23 Ulf Landegren Methods and kits for proximity probing
WO2003044231A1 (en) 2001-11-23 2003-05-30 Simon Fredriksson Method and kit for proximity probing with multivalent proximity probes
WO2004094456A2 (en) 2003-04-18 2004-11-04 Becton, Dickinson And Company Immuno-amplification
WO2005123963A2 (en) 2004-06-14 2005-12-29 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for use in analyte detection using proximity probes
WO2006137932A2 (en) 2004-11-03 2006-12-28 Leucadia Technologies, Inc. Homogeneous analyte detection
WO2007107743A1 (en) 2006-03-20 2007-09-27 Olink Ab Method for analyte detection using proximity probes
WO2013113699A2 (en) 2012-01-30 2013-08-08 Olink Ab Hyperthermophilic polymerase enabled proximity extension assay
WO2017068116A1 (en) 2015-10-21 2017-04-27 Olink Proteomics Ab Method for generating proximity probes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005225057A1 (en) * 1999-03-26 2005-12-01 Bp Corporation North America Inc. Synthetic ligation reassembly in directed evolution
WO2005079357A2 (en) * 2004-02-17 2005-09-01 Dana Farber Cancer Institute Nucleic acid representations utilizing type iib restriction endonuclease cleavage products
GB201101621D0 (en) 2011-01-31 2011-03-16 Olink Ab Method and product
US11898141B2 (en) * 2014-05-27 2024-02-13 The Broad Institute, Inc. High-throughput assembly of genetic elements
CN109844133A (zh) * 2016-08-15 2019-06-04 安可济控股有限公司 检测罕见序列变体的组合物和方法
WO2018108328A1 (en) * 2016-12-16 2018-06-21 F. Hoffmann-La Roche Ag Method for increasing throughput of single molecule sequencing by concatenating short dna fragments

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001061037A1 (en) 2000-02-18 2001-08-23 Ulf Landegren Methods and kits for proximity probing
WO2003044231A1 (en) 2001-11-23 2003-05-30 Simon Fredriksson Method and kit for proximity probing with multivalent proximity probes
WO2004094456A2 (en) 2003-04-18 2004-11-04 Becton, Dickinson And Company Immuno-amplification
WO2005123963A2 (en) 2004-06-14 2005-12-29 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for use in analyte detection using proximity probes
WO2006137932A2 (en) 2004-11-03 2006-12-28 Leucadia Technologies, Inc. Homogeneous analyte detection
WO2007107743A1 (en) 2006-03-20 2007-09-27 Olink Ab Method for analyte detection using proximity probes
WO2013113699A2 (en) 2012-01-30 2013-08-08 Olink Ab Hyperthermophilic polymerase enabled proximity extension assay
WO2017068116A1 (en) 2015-10-21 2017-04-27 Olink Proteomics Ab Method for generating proximity probes

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GEU-FLORES ET AL., NUCLEIC ACIDS RESEARCH, vol. 35, no. 7, 2007, pages e55
GIBSON ET AL., NATURE METHODS, vol. 6, 2009, pages 343 - 345
GIBSON ET AL., SCIENCE, vol. 329, 2010, pages 52 - 56
LUND ET AL., PLOS ONE, vol. 9, no. 5, 2014, pages e96693
SCHLECHT ET AL., SCIENTIFIC REPORTS, vol. 7, 2017, pages 5252

Also Published As

Publication number Publication date
JP2023550568A (ja) 2023-12-01
CN116745433A (zh) 2023-09-12
WO2022112300A1 (en) 2022-06-02
CA3199169A1 (en) 2022-06-02
US20220162589A1 (en) 2022-05-26
KR20230112647A (ko) 2023-07-27
AU2021388789A9 (en) 2025-03-27
IL303093A (en) 2023-07-01
EP4251762A1 (en) 2023-10-04
AU2021388789A1 (en) 2023-06-08

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Legal Events

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AT Applications terminated before publication under section 16(1)