GB202013057D0 - Method of making recombinant aavs - Google Patents

Method of making recombinant aavs

Info

Publication number
GB202013057D0
GB202013057D0 GBGB2013057.1A GB202013057A GB202013057D0 GB 202013057 D0 GB202013057 D0 GB 202013057D0 GB 202013057 A GB202013057 A GB 202013057A GB 202013057 D0 GB202013057 D0 GB 202013057D0
Authority
GB
United Kingdom
Prior art keywords
making recombinant
recombinant aavs
aavs
making
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2013057.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Oxford Genetics Ltd
Original Assignee
Oxford University Innovation Ltd
Oxford Genetics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd, Oxford Genetics Ltd filed Critical Oxford University Innovation Ltd
Priority to GBGB2013057.1A priority Critical patent/GB202013057D0/en
Publication of GB202013057D0 publication Critical patent/GB202013057D0/en
Priority to US18/021,675 priority patent/US20240026378A1/en
Priority to CA3189844A priority patent/CA3189844A1/en
Priority to EP21759123.9A priority patent/EP4200428B1/en
Priority to PCT/GB2021/052162 priority patent/WO2022038369A1/en
Priority to MX2023001936A priority patent/MX2023001936A/es
Priority to JP2023512464A priority patent/JP7853958B2/ja
Priority to AU2021327855A priority patent/AU2021327855A1/en
Priority to KR1020237009622A priority patent/KR20230074485A/ko
Priority to CN202180067893.XA priority patent/CN116419974A/zh
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10044—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10344—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/005—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB
    • C12N2830/006—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB tet repressible

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GBGB2013057.1A 2020-08-21 2020-08-21 Method of making recombinant aavs Ceased GB202013057D0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
GBGB2013057.1A GB202013057D0 (en) 2020-08-21 2020-08-21 Method of making recombinant aavs
CN202180067893.XA CN116419974A (zh) 2020-08-21 2021-08-20 重组aav的制备方法
PCT/GB2021/052162 WO2022038369A1 (en) 2020-08-21 2021-08-20 Method of making recombinant aavs
CA3189844A CA3189844A1 (en) 2020-08-21 2021-08-20 Method of making recombinant aavs
EP21759123.9A EP4200428B1 (en) 2020-08-21 2021-08-20 Method of making recombinant aavs
US18/021,675 US20240026378A1 (en) 2020-08-21 2021-08-20 Method of making recombinant aavs
MX2023001936A MX2023001936A (es) 2020-08-21 2021-08-20 Método de elaboración de aav recombinantes.
JP2023512464A JP7853958B2 (ja) 2020-08-21 2021-08-20 組み換えａａｖの作製方法
AU2021327855A AU2021327855A1 (en) 2020-08-21 2021-08-20 Method of making recombinant aavs
KR1020237009622A KR20230074485A (ko) 2020-08-21 2021-08-20 재조합 aav의 제조 방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2013057.1A GB202013057D0 (en) 2020-08-21 2020-08-21 Method of making recombinant aavs

Publications (1)

Publication Number Publication Date
GB202013057D0 true GB202013057D0 (en) 2020-10-07

Family

ID=72660685

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2013057.1A Ceased GB202013057D0 (en) 2020-08-21 2020-08-21 Method of making recombinant aavs

Country Status (10)

Country Link
US (1) US20240026378A1 (https=)
EP (1) EP4200428B1 (https=)
JP (1) JP7853958B2 (https=)
KR (1) KR20230074485A (https=)
CN (1) CN116419974A (https=)
AU (1) AU2021327855A1 (https=)
CA (1) CA3189844A1 (https=)
GB (1) GB202013057D0 (https=)
MX (1) MX2023001936A (https=)
WO (1) WO2022038369A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110892064A (zh) 2017-07-25 2020-03-17 牛津遗传学有限公司 腺病毒载体
GB201901571D0 (en) 2019-02-05 2019-03-27 Oxford Genetics Ltd Inducible AAV sysyem
US12054738B2 (en) 2020-07-30 2024-08-06 Shape Therapeutics Inc. Stable cell lines for inducible production of rAAV virions
TW202323529A (zh) 2021-10-18 2023-06-16 美商再生元醫藥公司 包括腺病毒相關病毒聚核苷酸的真核細胞

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019020992A1 (en) 2017-07-25 2019-01-31 Oxford Genetics Limited ADENOVIRAL VECTOR
WO2019020922A1 (fr) 2017-07-27 2019-01-31 Safran Procede et dispositif de recherche d'un defaut susceptible d'affecter un dispositif mecanique tournant de transmission de puissance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2453405A1 (en) 2001-07-13 2003-01-23 University Of Iowa Research Foundation Pseudotyped adeno-associated viruses and uses thereof
AU2003274397A1 (en) 2002-06-05 2003-12-22 University Of Florida Production of pseudotyped recombinant aav virions
AU2003265855A1 (en) 2002-08-28 2004-03-19 University Of Florida Modified aav
WO2009137006A2 (en) * 2008-04-30 2009-11-12 The University Of North Carolina At Chapel Hill Directed evolution and in vivo panning of virus vectors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019020992A1 (en) 2017-07-25 2019-01-31 Oxford Genetics Limited ADENOVIRAL VECTOR
WO2019020922A1 (fr) 2017-07-27 2019-01-31 Safran Procede et dispositif de recherche d'un defaut susceptible d'affecter un dispositif mecanique tournant de transmission de puissance

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ALTSCHUL ET AL., NUCLEIC ACIDS RES, vol. 25, 1997, pages 3389
ALTSCHUL ET AL.: "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", NUCLEIC ACIDS RES, vol. 25, 1997, pages 3389 - 3402, XP002905950, Retrieved from the Internet <URL:http://www.ncbi.nlm.nih.gov/BLAST> DOI: 10.1093/nar/25.17.3389
GREEN, MRSAMBROOK, J.: "Molecular Cloning: A Laboratory Manual", 2014
MA ET AL., BIOINFORMATICS, vol. 18, no. 3, March 2002 (2002-03-01), pages 440 - 5

Also Published As

Publication number Publication date
AU2021327855A1 (en) 2023-05-04
CA3189844A1 (en) 2022-02-24
EP4200428B1 (en) 2025-02-19
JP2023538409A (ja) 2023-09-07
US20240026378A1 (en) 2024-01-25
AU2021327855A9 (en) 2023-07-13
MX2023001936A (es) 2023-04-10
CN116419974A (zh) 2023-07-11
WO2022038369A1 (en) 2022-02-24
EP4200428A1 (en) 2023-06-28
KR20230074485A (ko) 2023-05-30
JP7853958B2 (ja) 2026-04-30

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)