GB2018712A - Xenobiotic delivery vehicles, method of forming them and method of using them - Google Patents

Xenobiotic delivery vehicles, method of forming them and method of using them

Info

Publication number
GB2018712A
GB2018712A GB7913056A GB7913056A GB2018712A GB 2018712 A GB2018712 A GB 2018712A GB 7913056 A GB7913056 A GB 7913056A GB 7913056 A GB7913056 A GB 7913056A GB 2018712 A GB2018712 A GB 2018712A
Authority
GB
United Kingdom
Prior art keywords
xenobiotic
forming
delivery vehicles
phospholipid
constituent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7913056A
Other versions
GB2018712B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arthur D Little Inc
Original Assignee
Arthur D Little Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arthur D Little Inc filed Critical Arthur D Little Inc
Publication of GB2018712A publication Critical patent/GB2018712A/en
Application granted granted Critical
Publication of GB2018712B publication Critical patent/GB2018712B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A delivery vehicle, suitable for delivering and releasing a xenobiotic to a mammalian host, to beneficially alter the pharmacodynamics (e.g. plasma kinetics, chemotherapeutic effectiveness, toxicity, oral absorption, tissue distribution, metabolism and the like) of the xenobiotic, is in the form of microreservoirs formed of a phospholipid constituent and a phospholipid-immiscible constituent. Xenobiotic binding agents and release agents may be added.
GB7913056A 1978-04-14 1979-04-12 Xenobiotic delivery vehicles method of forming them and method of using them Expired GB2018712B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89631178A 1978-04-14 1978-04-14

Publications (2)

Publication Number Publication Date
GB2018712A true GB2018712A (en) 1979-10-24
GB2018712B GB2018712B (en) 1982-09-08

Family

ID=25405992

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7913056A Expired GB2018712B (en) 1978-04-14 1979-04-12 Xenobiotic delivery vehicles method of forming them and method of using them

Country Status (7)

Country Link
JP (1) JPS5513260A (en)
CA (1) CA1119955A (en)
CH (1) CH637825A5 (en)
DE (1) DE2915028A1 (en)
FR (1) FR2422396A1 (en)
GB (1) GB2018712B (en)
IT (1) IT1193471B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280394A1 (en) * 1987-01-27 1988-08-31 Vestar, Inc. Phospholipid delivery vehicle for aqueous-insoluble active ingredients
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
US20070248541A1 (en) * 2003-12-01 2007-10-25 Mitsubishi Pharma Corporation Liposome

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588887A5 (en) * 1974-07-19 1977-06-15 Battelle Memorial Institute

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280394A1 (en) * 1987-01-27 1988-08-31 Vestar, Inc. Phospholipid delivery vehicle for aqueous-insoluble active ingredients
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US6599527B1 (en) 1997-06-20 2003-07-29 Phares Pharmaceutical Research N.V. Preparation of pharmaceutical compositions

Also Published As

Publication number Publication date
IT7921861A0 (en) 1979-04-13
DE2915028A1 (en) 1979-12-13
GB2018712B (en) 1982-09-08
IT1193471B (en) 1988-07-08
FR2422396B1 (en) 1983-03-11
CH637825A5 (en) 1983-08-31
JPS5513260A (en) 1980-01-30
CA1119955A (en) 1982-03-16
FR2422396A1 (en) 1979-11-09

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee