GB201812650D0 - Molecular assessment of TRBC usage - Google Patents

Molecular assessment of TRBC usage

Info

Publication number
GB201812650D0
GB201812650D0 GBGB1812650.8A GB201812650A GB201812650D0 GB 201812650 D0 GB201812650 D0 GB 201812650D0 GB 201812650 A GB201812650 A GB 201812650A GB 201812650 D0 GB201812650 D0 GB 201812650D0
Authority
GB
United Kingdom
Prior art keywords
trbc
usage
molecular assessment
assessment
molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1812650.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Autolus Ltd
Original Assignee
Autolus Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Autolus Ltd filed Critical Autolus Ltd
Priority to GBGB1812650.8A priority Critical patent/GB201812650D0/en
Publication of GB201812650D0 publication Critical patent/GB201812650D0/en
Priority to PCT/GB2019/052011 priority patent/WO2020025928A1/en
Priority to EP19745224.6A priority patent/EP3830297A1/en
Priority to JP2021505668A priority patent/JP7606958B2/ja
Priority to AU2019312877A priority patent/AU2019312877B2/en
Priority to CN201980051847.3A priority patent/CN112534065B/zh
Priority to CA3108000A priority patent/CA3108000A1/en
Priority to US17/264,217 priority patent/US12241124B2/en
Priority to JP2023211088A priority patent/JP2024023671A/ja
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GBGB1812650.8A 2018-08-03 2018-08-03 Molecular assessment of TRBC usage Ceased GB201812650D0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GBGB1812650.8A GB201812650D0 (en) 2018-08-03 2018-08-03 Molecular assessment of TRBC usage
PCT/GB2019/052011 WO2020025928A1 (en) 2018-08-03 2019-07-18 Molecular assessment of trbc usage
EP19745224.6A EP3830297A1 (en) 2018-08-03 2019-07-18 Molecular assessment of trbc usage
JP2021505668A JP7606958B2 (ja) 2018-08-03 2019-07-18 Trbc使用の分子的評価
AU2019312877A AU2019312877B2 (en) 2018-08-03 2019-07-18 Molecular assessment of TRBC usage
CN201980051847.3A CN112534065B (zh) 2018-08-03 2019-07-18 Trbc使用的分子评估
CA3108000A CA3108000A1 (en) 2018-08-03 2019-07-18 Molecular assessment of trbc usage
US17/264,217 US12241124B2 (en) 2018-08-03 2019-07-18 Molecular assessment of TRBC usage
JP2023211088A JP2024023671A (ja) 2018-08-03 2023-12-14 Trbc使用の分子的評価

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1812650.8A GB201812650D0 (en) 2018-08-03 2018-08-03 Molecular assessment of TRBC usage

Publications (1)

Publication Number Publication Date
GB201812650D0 true GB201812650D0 (en) 2018-09-19

Family

ID=63518375

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1812650.8A Ceased GB201812650D0 (en) 2018-08-03 2018-08-03 Molecular assessment of TRBC usage

Country Status (8)

Country Link
US (1) US12241124B2 (https=)
EP (1) EP3830297A1 (https=)
JP (2) JP7606958B2 (https=)
CN (1) CN112534065B (https=)
AU (1) AU2019312877B2 (https=)
CA (1) CA3108000A1 (https=)
GB (1) GB201812650D0 (https=)
WO (1) WO2020025928A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11385233B2 (en) 2015-03-05 2022-07-12 Autolus Limited Methods of depleting malignant T-cells
US11982673B2 (en) 2014-03-05 2024-05-14 Autolus Limited Methods
GB201709203D0 (en) 2017-06-09 2017-07-26 Autolus Ltd Antigen-binding domain
US12247060B2 (en) 2018-01-09 2025-03-11 Marengo Therapeutics, Inc. Calreticulin binding constructs and engineered T cells for the treatment of diseases
EP3765517A1 (en) 2018-03-14 2021-01-20 Elstar Therapeutics, Inc. Multifunctional molecules that bind to calreticulin and uses thereof
CA3105448A1 (en) 2018-07-03 2020-01-09 Elstar Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof
GB201817172D0 (en) 2018-10-22 2018-12-05 Autolus Ltd Antibody
GB201817822D0 (en) 2018-10-31 2018-12-19 Autolus Ltd Binding domain
GB2599228B (en) 2019-02-21 2024-02-07 Marengo Therapeutics Inc Multifunctional molecules that bind to T cell related cancer cells and uses thereof
CN119039441A (zh) 2019-02-21 2024-11-29 马伦戈治疗公司 与nkp30结合的抗体分子及其用途
AU2020416273A1 (en) 2020-01-03 2022-07-28 Marengo Therapeutics, Inc. Anti-TCR antibody molecules and uses thereof
WO2023236189A1 (zh) * 2022-06-10 2023-12-14 刘宗霖 利用非完整重组的t细胞受体核苷酸序列诊断t细胞淋巴瘤的方法及试剂盒

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102443624B (zh) * 2010-10-11 2014-12-10 遵义医学院 一种高通量同时测序多样本cdr3受体库的方法
CN103205420B (zh) 2012-01-13 2015-04-01 深圳华大基因科技有限公司 用于扩增T细胞受体β链CDR3编码序列的引物组合物及其用途
US11385233B2 (en) 2015-03-05 2022-07-12 Autolus Limited Methods of depleting malignant T-cells
DK3241561T3 (da) 2014-03-05 2025-06-30 Autolus Ltd Konjugeret antistof eller bispecifik t-celle-engager, som selektivt binder enten tcr-beta konstant region 1 (trbc1) eller trbc2
WO2016051205A1 (en) 2014-10-03 2016-04-07 Isis Innovation Limited Analysis of t-cell monotypia
EP3211003A1 (en) * 2016-02-24 2017-08-30 Institut Pasteur T cell receptors from the hiv-specific repertoire, means for their production and therapeutic uses thereof
CN110168105B (zh) 2016-12-09 2024-05-24 瑞泽恩制药公司 用于对t细胞受体进行测序的系统和方法及其用途
GB201709203D0 (en) 2017-06-09 2017-07-26 Autolus Ltd Antigen-binding domain
GB201800298D0 (en) 2018-01-09 2018-02-21 Autolus Ltd Method
GB201817172D0 (en) 2018-10-22 2018-12-05 Autolus Ltd Antibody
GB201817822D0 (en) 2018-10-31 2018-12-19 Autolus Ltd Binding domain

Also Published As

Publication number Publication date
CA3108000A1 (en) 2020-02-06
US12241124B2 (en) 2025-03-04
JP7606958B2 (ja) 2024-12-26
JP2024023671A (ja) 2024-02-21
JP2021532792A (ja) 2021-12-02
CN112534065B (zh) 2025-08-26
CN112534065A (zh) 2021-03-19
US20220010377A1 (en) 2022-01-13
WO2020025928A1 (en) 2020-02-06
EP3830297A1 (en) 2021-06-09
AU2019312877B2 (en) 2025-12-18
AU2019312877A1 (en) 2021-01-28

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)