GB201717578D0 - Novel T-cell receptor - Google Patents

Novel T-cell receptor

Info

Publication number
GB201717578D0
GB201717578D0 GBGB1717578.7A GB201717578A GB201717578D0 GB 201717578 D0 GB201717578 D0 GB 201717578D0 GB 201717578 A GB201717578 A GB 201717578A GB 201717578 D0 GB201717578 D0 GB 201717578D0
Authority
GB
United Kingdom
Prior art keywords
novel
cell receptor
receptor
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1717578.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University College Cardiff Consultants Ltd
Original Assignee
University College Cardiff Consultants Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University College Cardiff Consultants Ltd filed Critical University College Cardiff Consultants Ltd
Priority to GBGB1717578.7A priority Critical patent/GB201717578D0/en
Publication of GB201717578D0 publication Critical patent/GB201717578D0/en
Priority to GBGB1806155.6A priority patent/GB201806155D0/en
Priority to ES18795783T priority patent/ES2907819T3/es
Priority to MX2020004334A priority patent/MX2020004334A/es
Priority to JP2020543406A priority patent/JP7289311B2/ja
Priority to SG11202002537WA priority patent/SG11202002537WA/en
Priority to EP21214567.6A priority patent/EP4039700A1/en
Priority to CA3077635A priority patent/CA3077635A1/en
Priority to CN201880069546.9A priority patent/CN111278855B/zh
Priority to KR1020207011102A priority patent/KR20200078497A/ko
Priority to EA202091015A priority patent/EA202091015A1/ru
Priority to PL18795783T priority patent/PL3700925T3/pl
Priority to PCT/GB2018/053045 priority patent/WO2019081902A1/en
Priority to AU2018356944A priority patent/AU2018356944A1/en
Priority to DK18795783.2T priority patent/DK3700925T3/da
Priority to EP18795783.2A priority patent/EP3700925B8/en
Priority to BR112020007880-8A priority patent/BR112020007880A2/pt
Priority to IL274025A priority patent/IL274025A/en
Priority to US16/858,082 priority patent/US11725039B2/en
Priority to US17/153,329 priority patent/US11078252B2/en
Priority to AU2024202735A priority patent/AU2024202735A1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32T-cell receptors [TCR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GBGB1717578.7A 2017-10-26 2017-10-26 Novel T-cell receptor Ceased GB201717578D0 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
GBGB1717578.7A GB201717578D0 (en) 2017-10-26 2017-10-26 Novel T-cell receptor
GBGB1806155.6A GB201806155D0 (en) 2017-10-26 2018-04-16 Novel t-cell receptor
BR112020007880-8A BR112020007880A2 (pt) 2017-10-26 2018-10-22 receptor de células t
EA202091015A EA202091015A1 (ru) 2017-10-26 2018-10-22 Новый т-клеточный рецептор
PL18795783T PL3700925T3 (pl) 2017-10-26 2018-10-22 Nowatorski receptor komórek t
JP2020543406A JP7289311B2 (ja) 2017-10-26 2018-10-22 新規t細胞受容体
SG11202002537WA SG11202002537WA (en) 2017-10-26 2018-10-22 Novel t-cell receptor
EP21214567.6A EP4039700A1 (en) 2017-10-26 2018-10-22 Novel t-cell receptor
CA3077635A CA3077635A1 (en) 2017-10-26 2018-10-22 Novel t-cell receptor
CN201880069546.9A CN111278855B (zh) 2017-10-26 2018-10-22 新的t细胞受体
KR1020207011102A KR20200078497A (ko) 2017-10-26 2018-10-22 신규의 t-세포 수용체
ES18795783T ES2907819T3 (es) 2017-10-26 2018-10-22 Receptor novedoso de linfocitos T
MX2020004334A MX2020004334A (es) 2017-10-26 2018-10-22 Receptor de celulas t novedoso.
PCT/GB2018/053045 WO2019081902A1 (en) 2017-10-26 2018-10-22 NEW LYMPHOCYTE RECEPTOR T
AU2018356944A AU2018356944A1 (en) 2017-10-26 2018-10-22 Novel T-cell receptor
DK18795783.2T DK3700925T3 (en) 2017-10-26 2018-10-22 Hidtil ukendt t-cellereceptor
EP18795783.2A EP3700925B8 (en) 2017-10-26 2018-10-22 Novel t-cell receptor
IL274025A IL274025A (en) 2017-10-26 2020-04-19 A new T-cell receptor
US16/858,082 US11725039B2 (en) 2017-10-26 2020-04-24 α/β t-cell receptor and methods of using it
US17/153,329 US11078252B2 (en) 2017-10-26 2021-01-20 T-cell receptor
AU2024202735A AU2024202735A1 (en) 2017-10-26 2024-04-26 Novel T-cell receptor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1717578.7A GB201717578D0 (en) 2017-10-26 2017-10-26 Novel T-cell receptor

Publications (1)

Publication Number Publication Date
GB201717578D0 true GB201717578D0 (en) 2017-12-13

Family

ID=60580240

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1717578.7A Ceased GB201717578D0 (en) 2017-10-26 2017-10-26 Novel T-cell receptor
GBGB1806155.6A Ceased GB201806155D0 (en) 2017-10-26 2018-04-16 Novel t-cell receptor

Family Applications After (1)

Application Number Title Priority Date Filing Date
GBGB1806155.6A Ceased GB201806155D0 (en) 2017-10-26 2018-04-16 Novel t-cell receptor

Country Status (17)

Country Link
US (2) US11725039B2 (https=)
EP (2) EP3700925B8 (https=)
JP (1) JP7289311B2 (https=)
KR (1) KR20200078497A (https=)
CN (1) CN111278855B (https=)
AU (2) AU2018356944A1 (https=)
BR (1) BR112020007880A2 (https=)
CA (1) CA3077635A1 (https=)
DK (1) DK3700925T3 (https=)
EA (1) EA202091015A1 (https=)
ES (1) ES2907819T3 (https=)
GB (2) GB201717578D0 (https=)
IL (1) IL274025A (https=)
MX (1) MX2020004334A (https=)
PL (1) PL3700925T3 (https=)
SG (1) SG11202002537WA (https=)
WO (1) WO2019081902A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201717578D0 (en) * 2017-10-26 2017-12-13 Univ College Cardiff Consultants Ltd Novel T-cell receptor
KR20220147583A (ko) * 2020-01-09 2022-11-03 바이오뮤넥스 파마슈티컬스 Mait 및 종양 세포 둘 모두에 결합하는 다중특이적 항체
AU2021208955A1 (en) * 2020-01-16 2022-07-21 Universität Basel MR1 ligands and pharmaceutical compositions for immunomodulation
US20240016837A1 (en) * 2020-06-10 2024-01-18 Eutilex Co., Ltd. T-cell receptor binding to mr1, and use thereof
JP2023549098A (ja) * 2020-11-04 2023-11-22 フェイト セラピューティクス,インコーポレイティド 固形腫瘍を標的とする多重操作されたiPSC及び免疫エフェクター細胞
WO2022118043A1 (en) 2020-12-03 2022-06-09 Enara Bio Limited Novel protein-ligand complex
JPWO2022244876A1 (https=) * 2021-05-20 2022-11-24
WO2022248881A1 (en) 2021-05-28 2022-12-01 Enara Bio Limited Novel protein-ligand complex
CA3225252A1 (en) 2021-07-14 2023-01-19 Jordan JARJOUR Engineered t cell receptors fused to binding domains from antibodies
WO2023002204A1 (en) 2021-07-21 2023-01-26 Enara Bio Limited T-cell receptor
KR20230088292A (ko) * 2021-12-10 2023-06-19 주식회사 유틸렉스 MR1 제한적 Panck T 세포 및 이의 제조방법
WO2023148494A1 (en) 2022-02-03 2023-08-10 University College Cardiff Consultants Limited Novel t-cell receptor
CN119546328A (zh) 2022-04-08 2025-02-28 再生元制药公司 多部分受体和信号传导复合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI775117B (zh) * 2013-08-05 2022-08-21 德商伊瑪提克斯生物科技有限公司 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(二)
CN106103711A (zh) * 2013-11-21 2016-11-09 组库创世纪株式会社 T细胞受体和b细胞受体库分析系统及其在治疗和诊断中的应用
WO2018162563A1 (en) * 2017-03-07 2018-09-13 Universität Basel Mr1 restricted t cell receptors for cancer immunotherapy
GB201717578D0 (en) * 2017-10-26 2017-12-13 Univ College Cardiff Consultants Ltd Novel T-cell receptor

Also Published As

Publication number Publication date
EP3700925A1 (en) 2020-09-02
AU2018356944A1 (en) 2020-04-16
US11725039B2 (en) 2023-08-15
US20210147506A1 (en) 2021-05-20
EP3700925B1 (en) 2021-12-29
KR20200078497A (ko) 2020-07-01
JP2021500406A (ja) 2021-01-07
EA202091015A1 (ru) 2020-07-17
CN111278855A (zh) 2020-06-12
WO2019081902A1 (en) 2019-05-02
CA3077635A1 (en) 2019-05-02
JP7289311B2 (ja) 2023-06-09
DK3700925T3 (en) 2022-04-04
MX2020004334A (es) 2020-08-03
GB201806155D0 (en) 2018-05-30
EP3700925B8 (en) 2022-02-16
US20200369742A1 (en) 2020-11-26
PL3700925T3 (pl) 2022-05-02
BR112020007880A2 (pt) 2020-10-27
CN111278855B (zh) 2024-04-02
IL274025A (en) 2020-06-30
ES2907819T3 (es) 2022-04-26
EP4039700A1 (en) 2022-08-10
AU2024202735A1 (en) 2024-05-30
SG11202002537WA (en) 2020-05-28
US11078252B2 (en) 2021-08-03

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)