GB2015534A - Antigens bonded to muramylpeptides - Google Patents

Antigens bonded to muramylpeptides

Info

Publication number
GB2015534A
GB2015534A GB7906649A GB7906649A GB2015534A GB 2015534 A GB2015534 A GB 2015534A GB 7906649 A GB7906649 A GB 7906649A GB 7906649 A GB7906649 A GB 7906649A GB 2015534 A GB2015534 A GB 2015534A
Authority
GB
United Kingdom
Prior art keywords
muramylpeptides
antigens bonded
antigens
bonded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7906649A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27173419&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB2015534(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB2015534A publication Critical patent/GB2015534A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6062—Muramyl peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
GB7906649A 1978-02-24 1979-02-26 Antigens bonded to muramylpeptides Withdrawn GB2015534A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH203578 1978-02-24
CH377778 1978-04-07
CH539478 1978-05-18

Publications (1)

Publication Number Publication Date
GB2015534A true GB2015534A (en) 1979-09-12

Family

ID=27173419

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7906649A Withdrawn GB2015534A (en) 1978-02-24 1979-02-26 Antigens bonded to muramylpeptides

Country Status (20)

Country Link
EP (1) EP0003833B2 (en)
JP (1) JPS54141718A (en)
AR (1) AR223833A1 (en)
AT (1) AT364718B (en)
AU (1) AU527549B2 (en)
CA (1) CA1138436A (en)
DD (1) DD141616A5 (en)
DK (1) DK161026C (en)
ES (2) ES477977A1 (en)
FI (1) FI66878C (en)
GB (1) GB2015534A (en)
GR (1) GR77615B (en)
HU (1) HU182011B (en)
IL (1) IL56724A (en)
NO (2) NO151201C (en)
NZ (1) NZ189756A (en)
PL (1) PL123315B1 (en)
PT (1) PT69281A (en)
SU (1) SU1055312A3 (en)
ZA (1) ZA79893B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0038153A2 (en) * 1980-04-15 1981-10-21 Beecham Group Plc Modified allergens
US4335111A (en) 1978-12-22 1982-06-15 Agence National De Valorisation De La Recherche (Anvar) Compounds associating peptidyl of aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds
US4406889A (en) 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4427659A (en) 1979-02-20 1984-01-24 Agence Nationale De Valorisation De La Recherche (Anvar) Muramyl peptide substituted on a peptide nitrogen and medicaments containing the same
US4461761A (en) * 1978-06-05 1984-07-24 Agence Nationale De Valorisation De La Recherche (Anvar) Oligomers of compounds of the muramyl-peptide type and medicaments containing them
US4693998A (en) * 1978-06-05 1987-09-15 Agence Nationale De Valorisation De La Rechersche Novel compounds of the muramyl peptide

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130516A (en) * 1978-03-31 1979-10-09 Yuuichi Yamamura Acyllnnacetylmuramylpeptide derivativeeantigen combination
FR2446292A1 (en) * 1979-01-12 1980-08-08 Anvar MURAMYL-PEPTIDES FIXED ON PEPTIDE POLYMERS AND MEDICAMENTS CONTAINING THEM
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
DK156252C (en) * 1979-07-31 1989-12-18 Fujisawa Pharmaceutical Co METHOD OF ANALOGUE FOR THE PREPARATION OF DI, TRIAL OR TETRAPEPTIDE DERIVATIVES OR SALTS THEREOF
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4497729A (en) * 1980-12-01 1985-02-05 Fujisawa Pharmaceutical Co., Ltd. Peptide, process for preparation thereof and use thereof
FR2522967B1 (en) * 1982-03-15 1986-03-07 Anvar CONJUGATES OF HAPTENES AND MURAMYL-PEPTIDES, WITH IMMUNOGENIC ACTIVITY AND COMPOSITIONS CONTAINING THEM
US4587046A (en) * 1982-05-18 1986-05-06 The Regents Of The University Of California Drug-carrier conjugates
FR2558165B1 (en) * 1984-01-17 1986-07-04 Anvar NOVEL CONJUGATES OF OLIGO-MURAMYLPEPTIDES AND BIOLOGICAL COMPOSITIONS CONTAINING THEM FOR THE ACTIVATION OF MACROPHAGES
FR2569984B1 (en) * 1984-09-12 1987-08-14 Anvar SYNTHETIC MOLECULE CONTAINING A PLURALITY OF SEPARATE EPITOPES, PROCESS FOR OBTAINING SAME AND APPLICATION TO THE PRODUCTION OF POLYVACCINES
EP4308105A1 (en) 2021-03-19 2024-01-24 Trained Therapeutix Discovery, Inc. Compounds for regulating trained immunity, and their methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH453269A4 (en) * 1968-03-29 1973-01-31
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
JPS52139018A (en) * 1976-03-10 1977-11-19 Anvar Immuno adjuvant and antiinfection adjuvant composed of mainly nnacetyll muramiccllalanyllddglutamic ester or nnacetyllmuramiccllalanylldd isoglutamic ester
FR2343482A1 (en) * 1976-03-10 1977-10-07 Anvar LA 2- (2-ACETAMIDO-2-DEOXY-3-O-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE AND MEDICINES CONTAINING IT

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4461761A (en) * 1978-06-05 1984-07-24 Agence Nationale De Valorisation De La Recherche (Anvar) Oligomers of compounds of the muramyl-peptide type and medicaments containing them
US4693998A (en) * 1978-06-05 1987-09-15 Agence Nationale De Valorisation De La Rechersche Novel compounds of the muramyl peptide
US4335111A (en) 1978-12-22 1982-06-15 Agence National De Valorisation De La Recherche (Anvar) Compounds associating peptidyl of aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds
US4427659A (en) 1979-02-20 1984-01-24 Agence Nationale De Valorisation De La Recherche (Anvar) Muramyl peptide substituted on a peptide nitrogen and medicaments containing the same
US4406889A (en) 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
EP0038153A2 (en) * 1980-04-15 1981-10-21 Beecham Group Plc Modified allergens
EP0038153A3 (en) * 1980-04-15 1982-12-22 Beecham Group Plc Modified allergens

Also Published As

Publication number Publication date
AU527549B2 (en) 1983-03-10
FI790584A (en) 1979-08-25
FI66878C (en) 1984-12-10
AT364718B (en) 1981-11-10
FI66878B (en) 1984-08-31
PL123315B1 (en) 1982-10-30
DD141616A5 (en) 1980-05-14
PT69281A (en) 1979-03-01
ES483558A1 (en) 1980-04-16
ES477977A1 (en) 1980-01-16
JPH0130809B2 (en) 1989-06-22
ATA142079A (en) 1981-04-15
EP0003833A2 (en) 1979-09-05
IL56724A (en) 1982-12-31
NO151088C (en) 1985-02-06
EP0003833B2 (en) 1990-12-19
NO151201C (en) 1985-02-27
AU4454679A (en) 1979-08-30
EP0003833A3 (en) 1980-02-06
NZ189756A (en) 1982-05-31
NO790626L (en) 1979-08-27
SU1055312A3 (en) 1983-11-15
ZA79893B (en) 1980-03-26
HU182011B (en) 1983-12-28
DK161026B (en) 1991-05-21
CA1138436A (en) 1982-12-28
IL56724A0 (en) 1979-05-31
AR223833A1 (en) 1981-09-30
JPS54141718A (en) 1979-11-05
DK161026C (en) 1991-10-28
NO151088B (en) 1984-10-29
NO793993L (en) 1979-08-27
PL213696A1 (en) 1980-07-14
EP0003833B1 (en) 1983-07-20
DK79779A (en) 1979-08-25
GR77615B (en) 1984-09-25
NO151201B (en) 1984-11-19

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)