FR2343482A1 - LA 2- (2-ACETAMIDO-2-DEOXY-3-O-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE AND MEDICINES CONTAINING IT - Google Patents

LA 2- (2-ACETAMIDO-2-DEOXY-3-O-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE AND MEDICINES CONTAINING IT

Info

Publication number
FR2343482A1
FR2343482A1 FR7606819A FR7606819A FR2343482A1 FR 2343482 A1 FR2343482 A1 FR 2343482A1 FR 7606819 A FR7606819 A FR 7606819A FR 7606819 A FR7606819 A FR 7606819A FR 2343482 A1 FR2343482 A1 FR 2343482A1
Authority
FR
France
Prior art keywords
isoglutamine
seryl
glucopyranosyl
acetamido
deoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7606819A
Other languages
French (fr)
Other versions
FR2343482B1 (en
Inventor
Francoise Audibert
Louis Chedid
Pierre Lefrancier
Jean Choay
Edgar Lederer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Priority to FR7606819A priority Critical patent/FR2343482A1/en
Priority to US05/775,215 priority patent/US4153684A/en
Priority to CA273,415A priority patent/CA1107722A/en
Priority to GB10111/77A priority patent/GB1584791A/en
Priority to JP2553077A priority patent/JPS52116416A/en
Priority to NL7702580A priority patent/NL7702580A/en
Priority to DE19772710457 priority patent/DE2710457A1/en
Priority to BE175700A priority patent/BE852348A/en
Priority to CH305377A priority patent/CH619470A5/en
Publication of FR2343482A1 publication Critical patent/FR2343482A1/en
Application granted granted Critical
Publication of FR2343482B1 publication Critical patent/FR2343482B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/5555—Muramyl dipeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
FR7606819A 1976-03-10 1976-03-10 LA 2- (2-ACETAMIDO-2-DEOXY-3-O-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE AND MEDICINES CONTAINING IT Granted FR2343482A1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR7606819A FR2343482A1 (en) 1976-03-10 1976-03-10 LA 2- (2-ACETAMIDO-2-DEOXY-3-O-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE AND MEDICINES CONTAINING IT
US05/775,215 US4153684A (en) 1976-03-10 1977-03-07 Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives
CA273,415A CA1107722A (en) 1976-03-10 1977-03-08 2-(2-acetamido2-deoxy-3-o-d-glucopyranosy)-d- propionyl-l-seryl-d-isoglutamine, 2-(2-acetamido-2- deoxy-3-o-d-glucopyranosyl)-d-propionyl-l-seryl-d- glutamic acid, ester and amidederivatives thereof, and medicaments containing them
JP2553077A JPS52116416A (en) 1976-03-10 1977-03-10 22*22acetamidee22dioxyy33oodd glucopyranosyl**ddpropionyllllceryll ddisoglutamine or glutamic acid or adjuvants composed of mainly its ester or amide derivatives and said compound
GB10111/77A GB1584791A (en) 1976-03-10 1977-03-10 Muromyl peptide immunological adjuvants
NL7702580A NL7702580A (en) 1976-03-10 1977-03-10 PROCESS FOR PREPARING 2- (2-ACEET-AMIDO-2-DESOXY-3-OD-GLUCOPYRANOSYL) - -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE, 2- (2-ACEETAMI-DO-2-DESOXY- 3-OD-GLUCOPYRANOSYL) -D-PROPIONYL-L-SE-RYL-D-GLUTAMIC ACID AND ITS AMIDATED AND Esterified Derivatives AND METHOD FOR PREPARING THE PREPARATIONS CONTAINING THESE COMPOUNDS.
DE19772710457 DE2710457A1 (en) 1976-03-10 1977-03-10 2- (2-ACETAMIDO-2-DESOXY-3-0-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-ISOGLUTAMINE, 2- (2-ACETAMIDO-2-DESOXY-3-0- D-GLUCOPYRANOSYL) - D-PROPIONYL-L-SERYL- D-GLUTAMIC ACID, THE AMIDE AND ESTER DERIVATIVES OF THESE COMPOUNDS, THE PROCESS FOR THEIR PRODUCTION AND THESE COMPOUNDS CONTAINING THESE COMPOUNDS AS ACTIVE SUBSTANCES
BE175700A BE852348A (en) 1976-03-10 1977-03-10 2- (2-ACETAMIDO-2-DEOXY-3-0-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE
CH305377A CH619470A5 (en) 1976-03-10 1977-03-10 Process for the preparation of 2-(2-acetamido-2-deoxy-3-O-D-glucopyranosyl)-D-propionyl-L-seryl-D-iso glutamine and 2-(2-acetamido-2-deoxy-3-O-D-glucopyranosyl)-D-propionyl-L-seryl-D-glu tamic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7606819A FR2343482A1 (en) 1976-03-10 1976-03-10 LA 2- (2-ACETAMIDO-2-DEOXY-3-O-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE AND MEDICINES CONTAINING IT

Publications (2)

Publication Number Publication Date
FR2343482A1 true FR2343482A1 (en) 1977-10-07
FR2343482B1 FR2343482B1 (en) 1978-12-08

Family

ID=9170212

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7606819A Granted FR2343482A1 (en) 1976-03-10 1976-03-10 LA 2- (2-ACETAMIDO-2-DEOXY-3-O-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE AND MEDICINES CONTAINING IT

Country Status (8)

Country Link
JP (1) JPS52116416A (en)
BE (1) BE852348A (en)
CA (1) CA1107722A (en)
CH (1) CH619470A5 (en)
DE (1) DE2710457A1 (en)
FR (1) FR2343482A1 (en)
GB (1) GB1584791A (en)
NL (1) NL7702580A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1138436A (en) * 1978-02-24 1982-12-28 Gerhard Baschang Process for the manufacture of novel antigens
FR2428050A1 (en) * 1978-06-05 1980-01-04 Anvar OLIGOMERS OF MURAMYL-PEPTIDE COMPOUNDS AND DRUGS CONTAINING THEM
US4256735A (en) 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
US4391800A (en) 1979-04-27 1983-07-05 Merck & Co., Inc. Immunologically active peptidyl disaccharides and methods of preparation
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160326B1 (en) * 1971-11-19 1975-02-07 Anvar
GB1426042A (en) * 1971-11-26 1976-02-25 Anvar water-soluble immunological adjuvants
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Also Published As

Publication number Publication date
NL7702580A (en) 1977-09-13
CA1107722A (en) 1981-08-25
FR2343482B1 (en) 1978-12-08
GB1584791A (en) 1981-02-18
DE2710457A1 (en) 1977-09-15
BE852348A (en) 1977-09-12
JPS52116416A (en) 1977-09-29
CH619470A5 (en) 1980-09-30

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