AU527549B2 - Antigen derivatives - Google Patents

Antigen derivatives

Info

Publication number
AU527549B2
AU527549B2 AU44546/79A AU4454679A AU527549B2 AU 527549 B2 AU527549 B2 AU 527549B2 AU 44546/79 A AU44546/79 A AU 44546/79A AU 4454679 A AU4454679 A AU 4454679A AU 527549 B2 AU527549 B2 AU 527549B2
Authority
AU
Australia
Prior art keywords
antigen derivatives
antigen
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU44546/79A
Other versions
AU4454679A (en
Inventor
Gerhard Dr. Baschang
Felix M. Dietrich
Roland Gisler
Albert Hartmann
Jaroslav Stanek
Lajos Tarcsay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27173419&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU527549(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU4454679A publication Critical patent/AU4454679A/en
Application granted granted Critical
Publication of AU527549B2 publication Critical patent/AU527549B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55583Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6062Muramyl peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU44546/79A 1978-02-24 1979-02-23 Antigen derivatives Expired AU527549B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH2035780 1978-02-24
CH203578 1978-02-24
CH3777785 1978-04-07
CH377778 1978-04-07
CH5394780 1978-05-18
CH539478 1978-05-18

Publications (2)

Publication Number Publication Date
AU4454679A AU4454679A (en) 1979-08-30
AU527549B2 true AU527549B2 (en) 1983-03-10

Family

ID=27173419

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44546/79A Expired AU527549B2 (en) 1978-02-24 1979-02-23 Antigen derivatives

Country Status (20)

Country Link
EP (1) EP0003833B2 (en)
JP (1) JPS54141718A (en)
AR (1) AR223833A1 (en)
AT (1) AT364718B (en)
AU (1) AU527549B2 (en)
CA (1) CA1138436A (en)
DD (1) DD141616A5 (en)
DK (1) DK161026C (en)
ES (2) ES477977A1 (en)
FI (1) FI66878C (en)
GB (1) GB2015534A (en)
GR (1) GR77615B (en)
HU (1) HU182011B (en)
IL (1) IL56724A (en)
NO (2) NO151201C (en)
NZ (1) NZ189756A (en)
PL (1) PL123315B1 (en)
PT (1) PT69281A (en)
SU (1) SU1055312A3 (en)
ZA (1) ZA79893B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU570405B2 (en) * 1982-03-15 1988-03-17 Claude Carelli Conjugates of muramyl-peptides and haptenes

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130516A (en) * 1978-03-31 1979-10-09 Yuuichi Yamamura Acyllnnacetylmuramylpeptide derivativeeantigen combination
FR2428050A1 (en) * 1978-06-05 1980-01-04 Anvar OLIGOMERS OF MURAMYL-PEPTIDE COMPOUNDS AND DRUGS CONTAINING THEM
FR2428051A1 (en) * 1978-06-05 1980-01-04 Anvar NOVEL MURAMYL-PEPTIDE COMPOUNDS AND MEDICAMENTS CONTAINING THEM
EP0013856B1 (en) 1978-12-22 1983-03-09 ANVAR Agence Nationale de Valorisation de la Recherche New compounds associating peptidyl or aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds
FR2446292A1 (en) * 1979-01-12 1980-08-08 Anvar MURAMYL-PEPTIDES FIXED ON PEPTIDE POLYMERS AND MEDICAMENTS CONTAINING THEM
FR2449697A1 (en) * 1979-02-20 1980-09-19 Anvar NOVEL MURAMYL-PEPTIDES SUBSTITUTED ON PEPTIDE NITROGEN AND MEDICAMENTS CONTAINING THEM
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
DK156252C (en) * 1979-07-31 1989-12-18 Fujisawa Pharmaceutical Co METHOD OF ANALOGUE FOR THE PREPARATION OF DI, TRIAL OR TETRAPEPTIDE DERIVATIVES OR SALTS THEREOF
US4406889A (en) 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
EP0038153A3 (en) * 1980-04-15 1982-12-22 Beecham Group Plc Modified allergens
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4497729A (en) * 1980-12-01 1985-02-05 Fujisawa Pharmaceutical Co., Ltd. Peptide, process for preparation thereof and use thereof
US4587046A (en) * 1982-05-18 1986-05-06 The Regents Of The University Of California Drug-carrier conjugates
FR2558165B1 (en) * 1984-01-17 1986-07-04 Anvar NOVEL CONJUGATES OF OLIGO-MURAMYLPEPTIDES AND BIOLOGICAL COMPOSITIONS CONTAINING THEM FOR THE ACTIVATION OF MACROPHAGES
FR2569984B1 (en) * 1984-09-12 1987-08-14 Anvar SYNTHETIC MOLECULE CONTAINING A PLURALITY OF SEPARATE EPITOPES, PROCESS FOR OBTAINING SAME AND APPLICATION TO THE PRODUCTION OF POLYVACCINES
JPWO2020111238A1 (en) * 2018-11-30 2021-10-21 中外製薬株式会社 Deprotection method for peptide compounds or amide compounds, resin removal method for solid-phase reaction, and method for producing peptide compounds.
AU2022239614A1 (en) 2021-03-19 2023-10-12 Icahn School Of Medicine At Mount Sinai Compounds for regulating trained immunity, and their methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538003A (en) * 1968-03-29 1973-01-31 Anvar Process for obtaining textile articles carrying enzymes
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
JPS52139018A (en) * 1976-03-10 1977-11-19 Anvar Immuno adjuvant and antiinfection adjuvant composed of mainly nnacetyll muramiccllalanyllddglutamic ester or nnacetyllmuramiccllalanylldd isoglutamic ester
FR2343482A1 (en) * 1976-03-10 1977-10-07 Anvar LA 2- (2-ACETAMIDO-2-DEOXY-3-O-D-GLUCOPYRANOSYL) -D-PROPIONYL-L-SERYL-D-ISOGLUTAMINE AND MEDICINES CONTAINING IT

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU570405B2 (en) * 1982-03-15 1988-03-17 Claude Carelli Conjugates of muramyl-peptides and haptenes

Also Published As

Publication number Publication date
NO151088C (en) 1985-02-06
PT69281A (en) 1979-03-01
HU182011B (en) 1983-12-28
ZA79893B (en) 1980-03-26
FI790584A (en) 1979-08-25
GR77615B (en) 1984-09-25
ES477977A1 (en) 1980-01-16
JPS54141718A (en) 1979-11-05
ES483558A1 (en) 1980-04-16
NO790626L (en) 1979-08-27
DK161026B (en) 1991-05-21
DK161026C (en) 1991-10-28
AR223833A1 (en) 1981-09-30
EP0003833B1 (en) 1983-07-20
FI66878C (en) 1984-12-10
NO151201B (en) 1984-11-19
GB2015534A (en) 1979-09-12
NO151088B (en) 1984-10-29
PL123315B1 (en) 1982-10-30
EP0003833B2 (en) 1990-12-19
DD141616A5 (en) 1980-05-14
JPH0130809B2 (en) 1989-06-22
FI66878B (en) 1984-08-31
AT364718B (en) 1981-11-10
AU4454679A (en) 1979-08-30
CA1138436A (en) 1982-12-28
IL56724A0 (en) 1979-05-31
NO151201C (en) 1985-02-27
EP0003833A2 (en) 1979-09-05
ATA142079A (en) 1981-04-15
DK79779A (en) 1979-08-25
EP0003833A3 (en) 1980-02-06
SU1055312A3 (en) 1983-11-15
IL56724A (en) 1982-12-31
NZ189756A (en) 1982-05-31
NO793993L (en) 1979-08-27
PL213696A1 (en) 1980-07-14

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