GB201511512D0 - Use of cell-free nucleosomes as biomarkers - Google Patents

Use of cell-free nucleosomes as biomarkers

Info

Publication number
GB201511512D0
GB201511512D0 GBGB1511512.4A GB201511512A GB201511512D0 GB 201511512 D0 GB201511512 D0 GB 201511512D0 GB 201511512 A GB201511512 A GB 201511512A GB 201511512 D0 GB201511512 D0 GB 201511512D0
Authority
GB
United Kingdom
Prior art keywords
biomarkers
cell
free nucleosomes
nucleosomes
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1511512.4A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Singapore Volition Pte Ltd
Original Assignee
Singapore Volition Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Singapore Volition Pte Ltd filed Critical Singapore Volition Pte Ltd
Priority to GBGB1511512.4A priority Critical patent/GB201511512D0/en
Publication of GB201511512D0 publication Critical patent/GB201511512D0/en
Priority to JP2017568274A priority patent/JP7094700B2/ja
Priority to PCT/GB2016/051994 priority patent/WO2017001863A1/en
Priority to EP16736594.9A priority patent/EP3317671B1/en
Priority to CN201680050736.7A priority patent/CN108450000A/zh
Priority to HK18114236.5A priority patent/HK1255151B/en
Priority to US15/738,082 priority patent/US20180306804A1/en
Priority to ES16736594T priority patent/ES2772701T3/es
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875Nucleoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • G01N2800/122Chronic or obstructive airway disorders, e.g. asthma COPD
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB1511512.4A 2015-07-01 2015-07-01 Use of cell-free nucleosomes as biomarkers Ceased GB201511512D0 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GBGB1511512.4A GB201511512D0 (en) 2015-07-01 2015-07-01 Use of cell-free nucleosomes as biomarkers
JP2017568274A JP7094700B2 (ja) 2015-07-01 2016-07-01 喀痰試料中のバイオマーカーとしての細胞外遊離ヌクレオソームの使用
PCT/GB2016/051994 WO2017001863A1 (en) 2015-07-01 2016-07-01 Use of cell-free nucleosomes as biomarkers in sputum samples
EP16736594.9A EP3317671B1 (en) 2015-07-01 2016-07-01 Use of cell-free nucleosomes as biomarkers in sputum samples
CN201680050736.7A CN108450000A (zh) 2015-07-01 2016-07-01 痰液样本中无细胞的核小体作为生物标记的用途
HK18114236.5A HK1255151B (en) 2015-07-01 2016-07-01 Use of cell-free nucleosomes as biomarkers in sputum samples
US15/738,082 US20180306804A1 (en) 2015-07-01 2016-07-01 Use of cell-free nucleosomes as biomarkers in sputum samples
ES16736594T ES2772701T3 (es) 2015-07-01 2016-07-01 Uso de nucleosomas libres de células como biomarcadores en muestras de esputo

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1511512.4A GB201511512D0 (en) 2015-07-01 2015-07-01 Use of cell-free nucleosomes as biomarkers

Publications (1)

Publication Number Publication Date
GB201511512D0 true GB201511512D0 (en) 2015-08-12

Family

ID=53872486

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1511512.4A Ceased GB201511512D0 (en) 2015-07-01 2015-07-01 Use of cell-free nucleosomes as biomarkers

Country Status (7)

Country Link
US (1) US20180306804A1 (enExample)
EP (1) EP3317671B1 (enExample)
JP (1) JP7094700B2 (enExample)
CN (1) CN108450000A (enExample)
ES (1) ES2772701T3 (enExample)
GB (1) GB201511512D0 (enExample)
WO (1) WO2017001863A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3759249T3 (da) * 2018-03-01 2023-10-30 Epicypher Inc Kvantificering af nukleosommodifikationer ved anvendelse af kemisk definerede rekombinante nukleosomer
US11154240B2 (en) 2019-04-02 2021-10-26 Kpn Innovations Llc Methods and systems for utilizing diagnostics for informed vibrant constitutional guidance
GB201906199D0 (en) * 2019-05-02 2019-06-19 Belgian Volition Sprl Method for the detection of cancer
ES2988371T3 (es) * 2019-12-02 2024-11-20 Belgian Volition Srl Uso de nucleosomas libres de células como biomarcadores
US11289206B2 (en) 2020-06-02 2022-03-29 Kpn Innovations, Llc. Artificial intelligence methods and systems for constitutional analysis using objective functions
US12176108B2 (en) 2020-06-02 2024-12-24 Kpn Innovations Llc Artificial intelligence methods and systems for constitutional analysis using objective functions
US11211158B1 (en) 2020-08-31 2021-12-28 Kpn Innovations, Llc. System and method for representing an arranged list of provider aliment possibilities
GB202310137D0 (en) * 2023-07-03 2023-08-16 Belgian Volition Srl Method for the detection of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7229772B1 (en) * 1998-03-18 2007-06-12 Roche Diagnostics Gmbh Detection of apoptotic products
GB201012662D0 (en) 2010-07-28 2010-09-15 Valirx Plc Method for detecting the presence of a gynaecological growth
GB201115095D0 (en) 2011-09-01 2011-10-19 Singapore Volition Pte Ltd Method for detecting nucleosomes containing nucleotides
GB201115098D0 (en) * 2011-09-01 2011-10-19 Belgian Volition Sa Method for detecting nucleosomes containing histone variants
WO2013084002A2 (en) * 2011-12-07 2013-06-13 Singapore Volition Pte Limited Method for detecting nucleosome adducts
GB201303575D0 (en) * 2013-02-28 2013-04-10 Singapore Volition Pte Ltd Method for detecting histone modifications in nucleosomes
WO2015048535A1 (en) * 2013-09-27 2015-04-02 Natera, Inc. Prenatal diagnostic resting standards

Also Published As

Publication number Publication date
WO2017001863A1 (en) 2017-01-05
JP2018529931A (ja) 2018-10-11
CN108450000A (zh) 2018-08-24
ES2772701T3 (es) 2020-07-08
EP3317671B1 (en) 2019-11-13
HK1255151A1 (en) 2019-08-09
EP3317671A1 (en) 2018-05-09
US20180306804A1 (en) 2018-10-25
JP7094700B2 (ja) 2022-07-04

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)