GB201319548D0 - Amorphous magnesium-substituted calcium phosphate compositions and their uses - Google Patents

Amorphous magnesium-substituted calcium phosphate compositions and their uses

Info

Publication number
GB201319548D0
GB201319548D0 GBGB1319548.2A GB201319548A GB201319548D0 GB 201319548 D0 GB201319548 D0 GB 201319548D0 GB 201319548 A GB201319548 A GB 201319548A GB 201319548 D0 GB201319548 D0 GB 201319548D0
Authority
GB
United Kingdom
Prior art keywords
calcium phosphate
amorphous magnesium
phosphate compositions
substituted calcium
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1319548.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Research Council filed Critical Medical Research Council
Priority to GBGB1319548.2A priority Critical patent/GB201319548D0/en
Publication of GB201319548D0 publication Critical patent/GB201319548D0/en
Priority to EP14799845.4A priority patent/EP3065715B1/en
Priority to JP2016551077A priority patent/JP2016537408A/ja
Priority to BR112016009809A priority patent/BR112016009809A2/pt
Priority to AU2014345334A priority patent/AU2014345334B2/en
Priority to KR1020167014309A priority patent/KR20160079060A/ko
Priority to CA2929123A priority patent/CA2929123A1/en
Priority to CN201480060734.7A priority patent/CN105722504A/zh
Priority to US15/033,750 priority patent/US10596122B2/en
Priority to EA201690659A priority patent/EA201690659A1/ru
Priority to PCT/GB2014/053291 priority patent/WO2015067939A1/en
Priority to SG11201603261PA priority patent/SG11201603261PA/en
Priority to MX2016005415A priority patent/MX367473B/es
Priority to SG10201803562YA priority patent/SG10201803562YA/en
Priority to ES14799845T priority patent/ES2761559T3/es
Priority to ZA2016/02906A priority patent/ZA201602906B/en
Priority to IL245380A priority patent/IL245380B/en
Priority to JP2019173127A priority patent/JP2020073467A/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
GBGB1319548.2A 2013-11-05 2013-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses Ceased GB201319548D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB1319548.2A GB201319548D0 (en) 2013-11-05 2013-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses
ES14799845T ES2761559T3 (es) 2013-11-05 2014-11-05 Composiciones de fosfato de calcio sustituido con magnesio amorfo, y sus usos
US15/033,750 US10596122B2 (en) 2013-11-05 2014-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses
PCT/GB2014/053291 WO2015067939A1 (en) 2013-11-05 2014-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses
BR112016009809A BR112016009809A2 (pt) 2013-11-05 2014-11-05 composições de fosfato de cálcio amorfo substituído por magnésio e seus usos
AU2014345334A AU2014345334B2 (en) 2013-11-05 2014-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses
KR1020167014309A KR20160079060A (ko) 2013-11-05 2014-11-05 무정형의 마그네슘-치환된 인산칼슘 조성물 및 그의 용도
CA2929123A CA2929123A1 (en) 2013-11-05 2014-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses
CN201480060734.7A CN105722504A (zh) 2013-11-05 2014-11-05 无定形的镁取代磷酸钙组合物及其用途
EP14799845.4A EP3065715B1 (en) 2013-11-05 2014-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses
EA201690659A EA201690659A1 (ru) 2013-11-05 2014-11-05 Композиции аморфного магнийзамещенного фосфата кальция и их применение
JP2016551077A JP2016537408A (ja) 2013-11-05 2014-11-05 非晶質マグネシウム置換リン酸カルシウム組成物及びその使用
SG11201603261PA SG11201603261PA (en) 2013-11-05 2014-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses
MX2016005415A MX367473B (es) 2013-11-05 2014-11-05 Composiciones de fosfato de calcio sustituido con magnesio amorfo, y sus usos.
SG10201803562YA SG10201803562YA (en) 2013-11-05 2014-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses
ZA2016/02906A ZA201602906B (en) 2013-11-05 2016-04-29 Amorphous magnesium-substituted calcium phosphate compositions and their uses
IL245380A IL245380B (en) 2013-11-05 2016-05-01 Preparations of calcium phosphate transformed with amorphous magnesium and their uses
JP2019173127A JP2020073467A (ja) 2013-11-05 2019-09-24 非晶質マグネシウム置換リン酸カルシウム組成物及びその使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1319548.2A GB201319548D0 (en) 2013-11-05 2013-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses

Publications (1)

Publication Number Publication Date
GB201319548D0 true GB201319548D0 (en) 2013-12-18

Family

ID=49767709

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1319548.2A Ceased GB201319548D0 (en) 2013-11-05 2013-11-05 Amorphous magnesium-substituted calcium phosphate compositions and their uses

Country Status (16)

Country Link
US (1) US10596122B2 (https=)
EP (1) EP3065715B1 (https=)
JP (2) JP2016537408A (https=)
KR (1) KR20160079060A (https=)
CN (1) CN105722504A (https=)
AU (1) AU2014345334B2 (https=)
BR (1) BR112016009809A2 (https=)
CA (1) CA2929123A1 (https=)
EA (1) EA201690659A1 (https=)
ES (1) ES2761559T3 (https=)
GB (1) GB201319548D0 (https=)
IL (1) IL245380B (https=)
MX (1) MX367473B (https=)
SG (2) SG10201803562YA (https=)
WO (1) WO2015067939A1 (https=)
ZA (1) ZA201602906B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201319548D0 (en) 2013-11-05 2013-12-18 Medical Res Council Amorphous magnesium-substituted calcium phosphate compositions and their uses
FR3021045B1 (fr) * 2014-05-16 2020-02-21 Solvay Sa Procede de production d'un reactif phosphocalcique, reactif obtenu et son utilisation
KR101893110B1 (ko) * 2016-07-27 2018-08-31 삼일제약 주식회사 비페닐디메틸디카르복실레이트 및 마늘유를 포함하는 제제
EP3538659A4 (en) * 2016-11-09 2020-07-15 Engene, Inc. INTESTINAL EXPRESSION OF THE SCHEDULED DEATH LIGAND 1
CN110573455A (zh) * 2017-04-27 2019-12-13 武礼伟仁株式会社 羟基磷灰石、化妆品和食品及其生产方法
CN111417459B (zh) * 2019-07-05 2020-12-29 广州中大医疗器械有限公司 一种可载药微球及其制备方法
CN114615966B (zh) 2019-10-30 2025-10-10 皮斯洛克斯有限公司 稳定的非晶态钙镁磷酸盐颗粒组合物
CN116768175B (zh) * 2023-07-01 2025-12-19 常州市第二人民医院 高稳定性生物活性无定形磷酸钙镁的制备方法及应用
CN118929595A (zh) * 2024-08-30 2024-11-12 昆明理工大学 稳定型掺镁无定形磷酸钙纳米颗粒的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443832A (en) * 1990-04-16 1995-08-22 Institut Swisse De Recherches Experimentales Sur Le Cancer Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response
US6541037B1 (en) * 1995-05-19 2003-04-01 Etex Corporation Delivery vehicle
JP5097540B2 (ja) 2005-04-06 2012-12-12 株式会社サンギ 腸管吸収用抗腫瘍剤
CN101557720B (zh) 2006-12-12 2013-05-29 弗门尼舍有限公司 具有无定形金属盐作为载体的活性成分递送系统
WO2009135190A2 (en) * 2008-05-01 2009-11-05 Nod Pharmaceuticals, Inc. Therapeutic calcium phosphate particles and methods of making and using same
GB201319548D0 (en) 2013-11-05 2013-12-18 Medical Res Council Amorphous magnesium-substituted calcium phosphate compositions and their uses

Also Published As

Publication number Publication date
JP2016537408A (ja) 2016-12-01
JP2020073467A (ja) 2020-05-14
MX367473B (es) 2019-08-23
CA2929123A1 (en) 2015-05-14
SG11201603261PA (en) 2016-05-30
KR20160079060A (ko) 2016-07-05
MX2016005415A (es) 2017-03-01
US20160235683A1 (en) 2016-08-18
EP3065715B1 (en) 2019-10-02
EA201690659A1 (ru) 2016-10-31
IL245380B (en) 2019-02-28
WO2015067939A1 (en) 2015-05-14
AU2014345334A1 (en) 2016-05-19
ES2761559T3 (es) 2020-05-20
CN105722504A (zh) 2016-06-29
BR112016009809A2 (pt) 2017-12-05
EP3065715A1 (en) 2016-09-14
ZA201602906B (en) 2019-09-25
US10596122B2 (en) 2020-03-24
AU2014345334B2 (en) 2019-10-31
IL245380A0 (en) 2016-06-30
SG10201803562YA (en) 2018-06-28

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)