GB2012260B - 4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents - Google Patents

4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents

Info

Publication number
GB2012260B
GB2012260B GB7843032A GB7843032A GB2012260B GB 2012260 B GB2012260 B GB 2012260B GB 7843032 A GB7843032 A GB 7843032A GB 7843032 A GB7843032 A GB 7843032A GB 2012260 B GB2012260 B GB 2012260B
Authority
GB
United Kingdom
Prior art keywords
dihydroindoles
desacetoxy
hydroxyindole
pharmaceutical formulations
formulations containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7843032A
Other versions
GB2012260A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/848,837 external-priority patent/US4122082A/en
Priority claimed from US05/890,422 external-priority patent/US4195022A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB2012260A publication Critical patent/GB2012260A/en
Application granted granted Critical
Publication of GB2012260B publication Critical patent/GB2012260B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GB7843032A 1977-11-07 1978-11-02 4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents Expired GB2012260B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/848,837 US4122082A (en) 1977-11-07 1977-11-07 4-Desacetoxy-4-oxovinblastine
US05/890,422 US4195022A (en) 1978-03-27 1978-03-27 4-Desacetoxy-4α-hydroxyvinblastine and related compounds

Publications (2)

Publication Number Publication Date
GB2012260A GB2012260A (en) 1979-07-25
GB2012260B true GB2012260B (en) 1982-11-03

Family

ID=27126805

Family Applications (2)

Application Number Title Priority Date Filing Date
GB7843032A Expired GB2012260B (en) 1977-11-07 1978-11-02 4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents
GB8200664A Expired GB2089806B (en) 1977-11-07 1978-11-02 4-desacetoxy-oxo-indole-dyhydroindole intermediates

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB8200664A Expired GB2089806B (en) 1977-11-07 1978-11-02 4-desacetoxy-oxo-indole-dyhydroindole intermediates

Country Status (11)

Country Link
JP (1) JPS5473796A (en)
AR (1) AR227620A1 (en)
CH (1) CH638814A5 (en)
DK (1) DK147302C (en)
FR (1) FR2407935A1 (en)
GB (2) GB2012260B (en)
HU (1) HU184623B (en)
IE (1) IE47489B1 (en)
IL (1) IL55865A (en)
IT (1) IT1100920B (en)
LU (1) LU80474A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU185691B (en) * 1982-02-09 1985-03-28 Richter Gedeon Vegyeszet Process for preparing a new analgetic pharmaceutical composition
FR2894966B1 (en) * 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa NEW CRYSTALLINE FORM OF VINFLUNINE
USD973040S1 (en) * 2020-11-06 2022-12-20 Lite-On Electronics (Guangzhou) Limited Antenna monitoring tool box

Also Published As

Publication number Publication date
FR2407935B1 (en) 1981-06-26
JPS5473796A (en) 1979-06-13
LU80474A1 (en) 1979-03-19
IE47489B1 (en) 1984-04-04
CH638814A5 (en) 1983-10-14
AR227620A1 (en) 1982-11-30
DK494178A (en) 1979-05-08
IT1100920B (en) 1985-09-28
IT7829435A0 (en) 1978-11-03
IL55865A (en) 1982-11-30
IE782189L (en) 1979-05-07
FR2407935A1 (en) 1979-06-01
IL55865A0 (en) 1979-01-31
GB2089806A (en) 1982-06-30
GB2089806B (en) 1982-11-24
GB2012260A (en) 1979-07-25
DK147302C (en) 1985-01-02
DK147302B (en) 1984-06-12
HU184623B (en) 1984-09-28

Similar Documents

Publication Publication Date Title
NZ188872A (en) 9-(-heteroarylamino-alkylamino)-erthromycins and pharmaceutical compositions
PH11596A (en) 2'-4-dichloro-4'-benzoyureidodiphenyl ethers and their use as insecticides
NZ190966A (en) Prostanoid compounds and pharmaceutical compositions
NZ188170A (en) Propenylamines and pharmaceutical compositions
IL56407A (en) 4-amino-3-sulfamoylpyridyl derivatives and pharmaceutical compositions containing them
NZ187794A (en) 1-acyl-2-cynanoaziridines and immunestimulating pharmaceutical compositions
IL56076A (en) 2 alpha-cyano-4 alpha,5 alpha-epoxyandrostanes,their preparation and pharmaceutical compositions containing them
DE3069074D1 (en) 6-alpha-9-alpha-difluoro-16-beta-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
NZ194348A (en) Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions
NZ188531A (en) W-mercapto-propionamides and pharmaceutical compositions
IL57268A0 (en) Di-o-n-alkyl clycerol derivatives and pharmaceutical compositions containing them
IL54755A (en) Trans 2-substituted-5-phenyl-2,3,4,4a,5,9b-hexahydro-1h-pyrido(4,3-b)-indole derivatives and pharmaceutical compositions containing them
NZ187876A (en) Tetraline derivatives and pharmaceutical compositions
IL60376A (en) 3-diphenylmethyleneazetidines and pharmaceutical compositions containing them
IL54358A (en) 1-substituted-3-amino-6,7-dialkoxy-1h-1,2,4-benzothiadiazine-1-oxides,their preparation and pharmaceutical compositions containing them
NZ187851A (en) 3-substituted amino- 4-oxo-4h-1-benzopyranes and pharmaceutical compositions
JPS5517385A (en) Benzimidazolinone derivative and medical composition containing it
JPS5470255A (en) Nnbenzylanthracycline and pharmaceutical composition
GB2012260B (en) 4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents
IL59177A0 (en) Spiro-quinolylhydantoins and pharmaceutical compositions containing them
GB2010261B (en) Phenoxyalkanolamine derivatives the preparation thereof and pharmaceutical compositions containing them
JPS5535086A (en) Thazine derivative and medical composition
IL57882A0 (en) 2-thiophenecarboxamido-alkylmercaptans and pharmaceutical compositions containing them
NZ187337A (en) 5-phenyl-1h-3-benzazepines and pharmaceutical compositions
NZ189703A (en) N'-glucofuranosid-6-yl-n3-nitroso-ureas and pharmaceutical compositions

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee