GB2009732A - Disubstituted Piperazines - Google Patents

Disubstituted Piperazines

Info

Publication number
GB2009732A
GB2009732A GB7843885A GB7843885A GB2009732A GB 2009732 A GB2009732 A GB 2009732A GB 7843885 A GB7843885 A GB 7843885A GB 7843885 A GB7843885 A GB 7843885A GB 2009732 A GB2009732 A GB 2009732A
Authority
GB
United Kingdom
Prior art keywords
image
compounds
sulphur
sulphonyl
het
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7843885A
Other versions
GB2009732B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Priority to GB7843885A priority Critical patent/GB2009732B/en
Publication of GB2009732A publication Critical patent/GB2009732A/en
Application granted granted Critical
Publication of GB2009732B publication Critical patent/GB2009732B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides disubstituted piperazines of the general formula: <IMAGE> in which n is 1 or 2, X is oxygen and Y is sulphur or sulphonyl, or X and Y are both sulphur or sulphonyl, and Het is a 5- or 6-membered heterocyclic radical containing 1, 2 or 3 nitrogen and/or sulphur atoms, and which may be substituted by one or more alkyl radicals each having from 1 to 5 carbon atoms, and acid addition salts of such compounds. The invention also provides processes for preparing the compounds by condensing either <IMAGE> or Hal-Het with <IMAGE> Hal being chlorine or bromine, or by submitting to an alkylating reduction a mixture of <IMAGE> The invention further provides pharmaceutical compositions containing such compounds or their physiologically tolerable acid addition salts, especially for the treatment of central nervous system disorders and Parkinson's disease.
GB7843885A 1977-11-09 1978-11-09 Disubstituted piperazines processes for their preparation and pharmaceutical compositions containing them Expired GB2009732B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7843885A GB2009732B (en) 1977-11-09 1978-11-09 Disubstituted piperazines processes for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4664677 1977-11-09
GB7843885A GB2009732B (en) 1977-11-09 1978-11-09 Disubstituted piperazines processes for their preparation and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
GB2009732A true GB2009732A (en) 1979-06-20
GB2009732B GB2009732B (en) 1982-02-03

Family

ID=26265865

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7843885A Expired GB2009732B (en) 1977-11-09 1978-11-09 Disubstituted piperazines processes for their preparation and pharmaceutical compositions containing them

Country Status (1)

Country Link
GB (1) GB2009732B (en)

Also Published As

Publication number Publication date
GB2009732B (en) 1982-02-03

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee